Roy C Levitt

Professor of Clinical

  • 6695 Citations
1975 …2020

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2019

Effect of non-invasive intranasal neurostimulation on tear volume, dryness and ocular pain

Farhangi, M., Cheng, A. M., Baksh, B., Sarantopoulos, C. D., Felix, E. R., Levitt, R. C. & Galor, A., Jan 1 2019, (Accepted/In press) In : British Journal of Ophthalmology. 315065.

Research output: Contribution to journalArticle

Modification of the Neuropathic Pain Symptom Inventory for use in eye pain (NPSI-Eye)

Farhangi, M., Feuer, W., Galor, A., Bouhassira, D., Levitt, R. C., Sarantopoulos, C. D. & Felix, E. R., Jul 1 2019, In : Pain. 160, 7, p. 1541-1550 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL

Upadhyay, U., Zhuang, G. Z., Diatchenko, L., Parisien, M., Kang, Y., Sarantopoulos, K. D., Martin, E. R., Smithid, S. B., Maixner, W. & Levitt, R. C., Jun 1 2019, In : PLoS genetics. 15, 6, e1008226.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access
2 Scopus citations
2018

Epidemiology of discordance between symptoms and signs of dry eye

Ong, E. S., Felix, E., Levitt, R. C., Feuer, W. J., Sarantopoulos, K. D. & Galor, A., May 1 2018, In : British Journal of Ophthalmology. 102, 5, p. 674-679 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Epidemiology of Persistent Dry Eye-Like Symptoms After Cataract Surgery

Iglesias, E., Sajnani, R., Levitt, R. C., Sarantopoulos, K. D. & Galor, A., Jul 1 2018, In : Cornea. 37, 7, p. 893-898 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Epidemiology of Persistent Postsurgical Pain Manifesting as Dry Eye-Like Symptoms After Cataract Surgery

Sajnani, R., Raia, S., Gibbons, A., Chang, V., Karp, C., Sarantopoulos, K. D., Levitt, R. C. & Galor, A., Dec 1 2018, In : Cornea. 37, 12, p. 1535-1541 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice

Zhuang, G. Z., Upadhyay, U., Tong, X., Kang, Y., Erasso, D. M., Fu, E., Sarantopoulos, K. D., Martin, E. R., Wiltshire, T., Diatchenko, L., Smith, S. B., Maixner, W. & Levitt, R. C., Apr 24 2018, (Accepted/In press) In : Gene Therapy. p. 1-15 15 p.

Research output: Contribution to journalArticle

2 Scopus citations
1 Scopus citations

Noninvasive Electrical Stimulation for the Treatment of Chronic Ocular Pain and Photophobia

Sivanesan, E., Levitt, R. C., Sarantopoulos, K. D., Patin, D. & Galor, A., Jan 1 2018, (Accepted/In press) In : Neuromodulation.

Research output: Contribution to journalArticle

6 Scopus citations

Traumatic brain injury, dry eye and comorbid pain diagnoses in US veterans

Lee, C. J., Felix, E., Levitt, R. C., Eddy, C., Vanner, E. A., Feuer, W. J., Sarantopoulos, K. D. & Galor, A., May 1 2018, In : British Journal of Ophthalmology. 102, 5, p. 667-673 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Bulbar conjunctival microvascular responses in dry eye

Chen, W., Batawi, H. I. M., Alava, J. R., Galor, A., Yuan, J., Sarantopoulos, K. D., McClellan, A. L., Feuer, W. J., Levitt, R. C. & Wang, J., Apr 1 2017, In : Ocular Surface. 15, 2, p. 193-201 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Evidence that dry eye is a comorbid pain condition in a U.S. veteran population

Lee, C. J., Levitt, R. C., Felix, E. R., Sarantopoulos, C. D. & Galor, A., Nov 1 2017, In : Pain Reports. 2, 6, e629.

Research output: Contribution to journalArticle

4 Scopus citations

Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice

Fu, E., Erasso, D. M., Zhuang, G. Z., Upadhyay, U., Ozdemir, M., Wiltshire, T., Sarantopoulos, K. D., Smith, S. B., Maixner, W., Martin, E. R. & Levitt, R. C., Jan 1 2017, In : NeuroReport. 28, 18, p. 1215-1220 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Longitudinal examination of frequency of and risk factors for severe dry eye symptoms in us veterans

Ong, E. S., Alghamdi, Y. A., Levitt, R. C., McClellan, A. L., Lewis, G., Sarantopoulos, K. D., Felix, E. & Galor, A., Feb 1 2017, In : JAMA Ophthalmology. 135, 2, p. 116-123 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
4 Scopus citations
2016

Assessment of somatosensory function in patients with idiopathic dry eye symptoms

Galor, A., Levitt, R. C., McManus, K. T., Kalangara, J. P., Seiden, B. E., Park, J. J., Covington, D. B., Sarantopoulos, K. D. & Felix, E., Nov 1 2016, In : JAMA Ophthalmology. 134, 11, p. 1290-1298 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Characteristics of Ocular Pain Complaints in Patients With Idiopathic Dry Eye Symptoms

Kalangara, J. P., Galor, A., Levitt, R. C., Covington, D. B., McManus, K. T., Sarantopoulos, K. D. & Felix, E., Feb 29 2016, (Accepted/In press) In : Eye and Contact Lens.

Research output: Contribution to journalArticle

22 Scopus citations

Corneal mechanical thresholds negatively associate with dry eye and ocular pain symptoms

Spierer, O., Felix, E., McClellan, A. L., Parel, J-M. A., Gonzalez, A., Feuer, W. J., Sarantopoulos, K. D., Levitt, R. C., Ehrmann, K. & Galor, A., Feb 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 2, p. 617-625 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Dry Eye Profiles in Patients with a Positive Elevated Surface Matrix Metalloproteinase 9 Point-of-Care Test Versus Negative Patients

Lanza, N. L., McClellan, A. L., Batawi, H., Felix, E., Sarantopoulos, K. D., Levitt, R. C. & Galor, A., Apr 1 2016, In : Ocular Surface. 14, 2, p. 216-223 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
14 Scopus citations
23 Scopus citations

ω-3 tear film lipids correlate with clinical measures of dry eye

Walter, S. D., Gronert, K., McClellan, A. L., Levitt, R. C., Sarantopoulos, K. D. & Galor, A., May 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 6, p. 2472-2478 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
2015

Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway

Zhuang, G. Z., Keeler, B., Grant, J., Bianchi, L., Fu, E., Zhang, Y. P., Erasso, D. M., Cui, J. G., Wiltshire, T., Li, Q., Hao, S., Sarantopoulos, K. D., Candiotti, K. A., Wishnek, S. M., Smith, S. B., Maixner, W., Diatchenko, L., Martin, E. R. & Levitt, R. C., Mar 3 2015, In : PLoS One. 10, 3, e0118273.

Research output: Contribution to journalArticle

13 Scopus citations
45 Scopus citations

Dry eye symptoms align more closely to non-ocular conditions than to tear film parameters

Galor, A., Felix, E., Feuer, W. J., Shalabi, N., Martin, E. R., Margolis, T. P., Sarantopoulos, K. D. & Levitt, R. C., Aug 1 2015, In : British Journal of Ophthalmology. 99, 8, p. 1126-1129 4 p.

Research output: Contribution to journalArticle

42 Scopus citations
40 Scopus citations

Human Tear Serotonin Levels Correlate with Symptoms and Signs of Dry Eye

Chhadva, P., Lee, T., Sarantopoulos, K. D., Hackam, A. S., McClellan, A. L., Felix, E., Levitt, R. C. & Galor, A., Aug 1 2015, In : Ophthalmology. 122, 8, p. 1675-1680 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Neuropathic ocular pain: An important yet underevaluated feature of dry eye

Galor, A., Levitt, R. C., Felix, E., Martin, E. R. & Sarantopoulos, K. D., Mar 15 2015, In : Eye (Basingstoke). 29, 3, p. 301-312 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

Neuropathic Ocular Pain due to Dry Eye Is Associated With Multiple Comorbid Chronic Pain Syndromes

Galor, A., Covington, D., Levitt, A. E., McManus, K. T., Seiden, B., Felix, E., Kalangara, J., Feuer, W. J., Patin, D., Martin, E. R., Sarantopoulos, K. D. & Levitt, R. C., Aug 10 2015, (Accepted/In press) In : Journal of Pain.

Research output: Contribution to journalArticle

34 Scopus citations

Understanding the true burden of dry eye disease

Galor, A., Levitt, R. C., Felix, E. & Sarantopoulos, K. D., Sep 3 2015, In : Expert Review of Ophthalmology. 10, 5, p. 403-405 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Agrin requires specific proteins to selectively activate γ-aminobutyric acid neurons for pain suppression

Erasso, D., Tender, G., Levitt, R. C. & Cui, J. G., Jan 1 2014, In : Experimental Neurology. 261, p. 646-653 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

HSV-mediated p55TNFSR reduces neuropathic pain induced by HIV gp120 in rats through CXCR4 activity

Huang, W., Zheng, W., Liu, S., Zeng, W., Levitt, R. C., Candiotti, K. A., Lubarsky, D. & Hao, S., Mar 1 2014, In : Gene Therapy. 21, 3, p. 328-336 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

IL-10 mediated by herpes simplex virus vector reduces neuropathic pain induced by HIV gp120 combined with ddC in rats

Zheng, W., Huang, W., Liu, S., Levitt, R. C., Candiotti, K. A., Lubarsky, D. & Hao, S., Jul 30 2014, In : Molecular Pain. 10, 1, 49.

Research output: Contribution to journalArticle

22 Scopus citations

Mechanical allodynia induced by nucleoside reverse transcriptase inhibitor is suppressed by p55TNFSR mediated by herpes simplex virus vector through the SDF1 alpha/CXCR4 system in rats

Huang, W., Zheng, W., Ouyang, H., Yi, H., Liu, S., Zeng, W., Levitt, R. C., Candiotti, K. A., Lubarsky, D. & Hao, S., Mar 1 2014, In : Anesthesia and Analgesia. 118, 3, p. 671-680 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2013
28 Scopus citations

Prophylactic and antinociceptive effects of coenzyme q10 on diabetic neuropathic pain in a mouse model of type 1 diabetes

Zhang, Y. P., Eber, A., Yuan, Y., Yang, Z., Rodriguez, Y., Levitt, R. C., Takacs, P. & Candiotti, K. A., Apr 1 2013, In : Anesthesiology. 118, 4, p. 945-954 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2012

An emerging new paradigm in opioid withdrawal: A critical role for glia-neuron signaling in the periaqueductal gray

Ouyang, H., Liu, S., Zeng, W., Levitt, R. C., Candiotti, K. A. & Hao, S., Sep 18 2012, In : The Scientific World Journal. 2012, 940613.

Research output: Contribution to journalArticle

13 Scopus citations

Crosstalk between JNK and NF-κB in the KDO2-mediated production of TNFα in HAPI cells.

Zheng, X., Zheng, W., Liu, S., Patel, H. M., Xia, X., Ouyang, H., Levitt, R. C., Candiotti, K. A. & Hao, S., 2012, In : Cellular and Molecular Neurobiology. 32, 8, p. 1375-1383 9 p.

Research output: Contribution to journalArticle

4 Scopus citations