Rong G Zhai

Associate Professor

  • 2701 Citations
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Nicotinamide-Nucleotide Adenylyltransferase Medicine & Life Sciences
Drosophila Medicine & Life Sciences
Synapses Medicine & Life Sciences
Synaptic Vesicles Medicine & Life Sciences
Nicotinamide Mononucleotide Medicine & Life Sciences
Proteins Medicine & Life Sciences
Diptera Medicine & Life Sciences
Tauopathies Medicine & Life Sciences

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Projects 2008 2018

Enhance Neuroprotection through post-transcriptional regulations

Zhai, R. G.

National Institutes of Health


Project: Research projectHigh Priority, Short Term Project Award

Protein Isoforms
Alternative Splicing

Functional Interaction of GBAS and SLC41A2 in Drosophila models for UDP_755

Zhai, R. G.

National Institutes of Health


Project: Research projectExploratory/Developmental Grants

Uridine Diphosphate

Mechanisms of Neuronal Maintenance and Protection.

Zhai, R. G.

National Institutes of Health


Project: Research projectResearch Project, High Priority, Short Term Project Award


Research Output 1997 2019

  • 2701 Citations
  • 41 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Review article

Discovery, synthesis of novel fusidic acid derivatives possessed amino-terminal groups at the 3-hydroxyl position with anticancer activity

Ni, J., Guo, M., Cao, Y., Lei, L., Liu, K., Wang, B., Lu, F., Zhai, R. G., Gao, X., Yan, C., Wang, H. & Bi, Y., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 122-131 10 p.

Research output: Contribution to journalArticle

Fusidic Acid
Hydroxyl Radical

Dysfunction of GRAP, encoding the GRB2-related adaptor protein, is linked to sensorineural hearing loss

Li, C., Bademci, G., Subasioglu, A., Diaz-Horta, O., Zhu, Y., Liu, J., Mitchell, T. G., Abad, C., Seyhan, S., Duman, D., Cengiz, F. B., Tokgoz-Yilmaz, S., Blanton, S. H., Farooq, A., Walz, K., Zhai, R. G. & Tekin, M., Jan 22 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 4, p. 1347-1352 6 p.

Research output: Contribution to journalArticle

GRB2 Adaptor Protein
Sensorineural Hearing Loss
Auditory Hair Cells

Synthesis and biological evaluation of novel H6 analogues as drug resistance reversal agents

Wang, X., Ren, Q. W., Liu, X. X., Yang, Y. T., Wang, B. H., Zhai, R. G., Qi, J. G., Tian, J. W., Wang, H. B. & Bi, Y., Jan 1 2019, In : European Journal of Medicinal Chemistry. 161, p. 364-377 14 p.

Research output: Contribution to journalArticle

Drug Resistance
Pharmaceutical Preparations
G2 Phase

Erratum: Publisher Correction: Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome (Nature communications (2017) 8 1 (1257))

Li, C., Brazill, J. M., Liu, S., Bello, C., Zhu, Y., Morimoto, M., Cascio, L., Pauly, R., Diaz-Perez, Z., Malicdan, M. C. V., Wang, H., Boccuto, L., Schwartz, C. E., Gahl, W. A., Boerkoel, C. F. & Zhai, R. G., Jan 18 2018, In : Nature communications. 9, 1, 1 p.

Research output: Contribution to journalComment/debate

Spermine Synthase
Oxidative stress
Oxidative Stress
8 Citations

H6, a novel hederagenin derivative, reverses multidrug resistance in vitro and in vivo

Yang, Y., Guan, D., Lei, L., Lu, J., Liu, J. Q., Yang, G., Yan, C., Zhai, R. G., Tian, J., Bi, Y., Fu, F. & Wang, H., Feb 15 2018, In : Toxicology and Applied Pharmacology. 341, p. 98-105 8 p.

Research output: Contribution to journalArticle

Multiple Drug Resistance
Rhodamine 123