Robert B Levy

Professor

  • 2778 Citations
1976 …2019
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  • 26 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
Graft vs Host Disease Medicine & Life Sciences
Transplants Medicine & Life Sciences
T-cells Chemical Compounds
Perforin Medicine & Life Sciences
Haptens Medicine & Life Sciences
Major Histocompatibility Complex Medicine & Life Sciences
Bone Marrow Transplantation Medicine & Life Sciences

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Projects 1993 2019

Immune Mechanisms in Ocular Graft versus Host Disease

Perez Quinones, V. L., Levy, R. B., Perez Quinones, V. L. & Levy, R. B.

National Institutes of Health

5/1/144/30/19

Project: Research project

Graft vs Host Disease
T-Lymphocytes
Tissue Donors
Eye Pain
Corneal Perforation
Cell Survival
T-Lymphocytes
Transplants
Hematopoietic Stem Cells
Antigens
Allografts
Bone Marrow
Stem Cells
T-Lymphocytes
Perforin
Animal Models
Perforin
Minor Histocompatibility Antigens
Receptors, Tumor Necrosis Factor, Type II
Fas Ligand Protein
Muromegalovirus
Animal Models
T-Lymphocytes
Viruses
Transplants

Research Output 1976 2019

Modeling Chronic Graft-versus-Host Disease in MHC-Matched Mouse Strains: Genetics, Graft Composition, and Tissue Targets

Müller, A. M. S., Min, D., Wernig, G., Levy, R. B., Perez, V. L., Herretes, S., Florek, M., Burnett, C., Weinberg, K. & Shizuru, J. A., Jan 1 2019, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Graft vs Host Disease
Hematopoietic Stem Cells
T-Lymphocytes
Transplants
Th17 Cells

The promise of CD4+FoxP3+ regulatory T-cell manipulation in vivo: Applications for allogeneic hematopoietic stem cell transplantation

Copsel, S., Wolf, D., Komanduri, K. V. & Levy, R. B., Jun 30 2019, In : Haematologica. 104, 7, p. 1309-1321 13 p.

Research output: Contribution to journalArticle

Open Access
Hematopoietic Stem Cell Transplantation
Regulatory T-Lymphocytes
Interleukin-2
Autoimmune Diseases
Graft vs Host Disease
1 Citation (Scopus)

BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT

Copsel, S. N., Lightbourn, C. O., Barreras, H., Lohse, I., Wolf, D., Bader, C. S., Manov, J., Kale, B. J., Shah, D., Brothers, S. P., Perez, V. L., Komanduri, K. V., Wahlestedt, C. R. & Levy, R. B., Jan 1 2018, In : Frontiers in immunology. 9, 1 p.

Research output: Contribution to journalArticle

Open Access
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Interleukin-2
Regulatory T-Lymphocytes
Phenotype
3 Citations (Scopus)

Superior immune reconstitution using Treg-expanded donor cells versus PTCy treatment in preclinical HSCT models

Wolf, D., Bader, C. S., Barreras, H., Copsel, S., Pfeiffer, B., Lightbourn, C. O., Altman, N. H., Komanduri, K. V. & Levy, R. B., Oct 18 2018, In : JCI insight. 3, 20

Research output: Contribution to journalArticle

Open Access
Cyclophosphamide
Tissue Donors
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Transplants
5 Citations (Scopus)

Very Low Numbers of CD4+ FoxP3+ Tregs Expanded in Donors via TL1A-Ig and Low-Dose IL-2 Exhibit a Distinct Activation/Functional Profile and Suppress GVHD in a Preclinical Model

Copsel, S., Wolf, D., Kale, B., Barreras, H., Lightbourn, C. O., Bader, C. S., Alperstein, W., Altman, N. H., Komanduri, K. V. & Levy, R. B., Jan 1 2018, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Graft vs Host Disease
Interleukin-2
Hematopoietic Stem Cell Transplantation
Tumor Necrosis Factor Receptors
Immune Tolerance