Richard S Jope

Professor

  • 19170 Citations
1974 …2021
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Fingerprint Dive into the research topics where Richard S Jope is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Glycogen Synthase Kinase 3 Medicine & Life Sciences
Lithium Medicine & Life Sciences
Brain Medicine & Life Sciences
Phosphatidylinositols Medicine & Life Sciences
Choline Medicine & Life Sciences
Hydrolysis Medicine & Life Sciences
Cholinergic Agents Medicine & Life Sciences
Acetylcholine Medicine & Life Sciences

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Projects 1984 2021

Toll-Like Receptor 2
Toll-Like Receptor 4
Depression
Antidepressive Agents
Therapeutics
Immune System
Depression
Glycogen Synthase Kinase 3
T-Lymphocytes
Th17 Cells
Glycogen Synthase Kinases
Apoptosis
Neuronal Plasticity
Thapsigargin
Alzheimer Disease
Oxidants
Alzheimer Disease
Oxidative Stress
Glycogen Synthase Kinases
Muscarinic Receptors
lithium
seizures
calcium
testing
synaptosomes

Research Output 1974 2018

3 Citations (Scopus)

Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome

Kozikowski, A. P., Shen, S., Pardo, M., Tavares, M. T., Szarics, D., Benoy, V., Zimprich, C. A., Kutil, Z., Zhang, G., Bařinka, C., Robers, M. B., Van Den Bosch, L., Eubanks, J. H. & Jope, R. S., Jan 1 2018, (Accepted/In press) In : ACS Chemical Neuroscience.

Research output: Contribution to journalArticle

Fragile X Syndrome
Histone Deacetylase Inhibitors
Histone Deacetylases
Brain
Tubulin
3 Citations (Scopus)

Distinct characteristics of hippocampal pathogenic TH17 cells in a mouse model of depression

Beurel, E., Lowell, J. A. & Jope, R. S., Jan 1 2018, (Accepted/In press) In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

Th17 Cells
Depression
Learned Helplessness
Hippocampus
T-Lymphocytes
23 Citations (Scopus)

TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice

Cheng, Y., Desse, S., Martinez, A., Worthen, R. J., Jope, R. S. & Beurel, E., Jan 1 2018, (Accepted/In press) In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

Learned Helplessness
Blood-Brain Barrier
Tumor Necrosis Factor-alpha
Glycogen Synthase Kinase 3
Tight Junction Proteins
9 Citations (Scopus)

Cotinine administration improves impaired cognition in the mouse model of Fragile X syndrome

Pardo, M., Beurel, E. & Jope, R. S., Feb 1 2017, In : European Journal of Neuroscience. 45, 4, p. 490-498 9 p.

Research output: Contribution to journalArticle

Fragile X Syndrome
Cotinine
Glycogen Synthase Kinase 3
Cognition
Serine

Glycogen Synthase Kinase-3: Abnormalities and Therapeutic Potential in Fragile X Syndrome

Jope, R. S., May 26 2017, Fragile X Syndrome: From Genetics to Targeted Treatment. Elsevier, p. 261-275 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Glycogen Synthase Kinase 3
Fragile X Syndrome
Lithium
Knockout Mice
Therapeutics