Richard K Lee

Associate Professor

  • 2618 Citations
1991 …2019
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Research Output 1991 2019

2019
1 Citation (Scopus)

Association of a Primary Open-Angle Glaucoma Genetic Risk Score with Earlier Age at Diagnosis

Fan, B. J., Bailey, J. C., Igo, R. P., Kang, J. H., Boumenna, T., Brilliant, M. H., Budenz, D. L., Fingert, J. H., Gaasterland, T., Gaasterland, D., Hauser, M. A., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Moroi, S. E., Myers, J. S., Pericak-Vance, M. A., Realini, A., Rhee, D. J. & 13 others, Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Weinreb, R. N., Wollstein, G., Zack, D. J., Haines, J. L., Pasquale, L. R. & Wiggs, J. L., Oct 2019, In : JAMA ophthalmology. 137, 10, p. 1190-1194 5 p.

Research output: Contribution to journalArticle

Glaucoma
National Eye Institute (U.S.)
Medical Genetics
Primary Open Angle Glaucoma
Genes

Differential Gamma-Synuclein Expression in Acute and Chronic Retinal Ganglion Cell Death in the Retina and Optic Nerve

Liu, Y., Tapia, M. L., Yeh, J., He, R. C., Pomerleu, D. & Lee, R. K., Jan 1 2019, (Accepted/In press) In : Molecular Neurobiology.

Research output: Contribution to journalArticle

gamma-Synuclein
Retinal Ganglion Cells
Optic Nerve
Retina
Cell Death

Low-cost, smartphone-based frequency doubling technology visual field testing using a head-mounted display

Alawa, K. A. R., Nolan, R. P., Han, E., Arboleda, A., Durkee, H., Sayed, M. S., Aguilar, M. C. & Lee, R. K., Jan 1 2019, (Accepted/In press) In : British Journal of Ophthalmology.

Research output: Contribution to journalArticle

Visual Fields
Head
Technology
Costs and Cost Analysis
Visual Field Tests

Peripheral vaso-occlusive events following trauma in patients with sickle cell trait

Camp, A. S., Read, S. P. & Lee, R. K., Mar 1 2019, In : Ophthalmic Surgery Lasers and Imaging Retina. 50, 3, p. E84-E87

Research output: Contribution to journalArticle

Sickle Cell Trait
Intraocular Pressure
Wounds and Injuries
Hemoglobins
2018
5 Citations (Scopus)

Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma

Gharahkhani, P., Burdon, K. P., Cooke Bailey, J. N., Hewitt, A. W., Law, M. H., Pasquale, L. R., Kang, J. H., Haines, J. L., Souzeau, E., Zhou, T., Siggs, O. M., Landers, J., Awadalla, M., Sharma, S., Mills, R. A., Ridge, B., Lynn, D., Casson, R., Graham, S. L., Goldberg, I. & 45 others, White, A., Healey, P. R., Grigg, J., Lawlor, M., Mitchell, P., Ruddle, J., Coote, M., Walland, M., Best, S., Vincent, A., Gale, J., Radfordsmith, G., Whiteman, D. C., Montgomery, G. W., Martin, N. G., MacKey, D. A., Wiggs, J. L., MacGregor, S., Craig, J. E., Allingham, R. R., Brilliant, M., Budenz, D. L., Fingert, J. H., Gaasterland, D., Gaasterland, T., Hark, L., Hauser, M., Igo, R. P., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Moroi, S., Pericak-Vance, M. A., Realini, A., Rhee, D., Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G. & Zack, D. J., Dec 1 2018, In : Scientific Reports. 8, 1, 3124.

Research output: Contribution to journalArticle

Open Angle Glaucoma
Glaucoma
Genome-Wide Association Study
Eye Diseases
Chromosome Mapping

Corneal Biomechanical Properties and Their Role in Glaucoma Diagnosis and Management

Sayed, M. S. & Lee, R. K., Jan 1 2018, In : International Ophthalmology Clinics. 58, 3, p. 35-49 15 p.

Research output: Contribution to journalArticle

Glaucoma
6 Citations (Scopus)

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Iglesias, A. I., Mishra, A., Vitart, V., Bykhovskaya, Y., Höhn, R., Springelkamp, H., Cuellar-Partida, G., Gharahkhani, P., Bailey, J. N. C., Willoughby, C. E., Li, X., Yazar, S., Nag, A., Khawaja, A. P., Polašek, O., Siscovick, D., Mitchell, P., Tham, Y. C., Haines, J. L., Kearns, L. S. & 124 others, Hayward, C., Shi, Y., Van Leeuwen, E. M., Taylor, K. D., Wang, J. J., Rochtchina, E., Attia, J., Scott, R., Holliday, E. G., Baird, P. N., Xie, J., Inouye, M., Viswanathan, A., Sim, X., Bonnemaijer, P., Rotter, J. I., Martin, N. G., Zeller, T., Mills, R. A., Staffieri, S. E., Jonas, J. B., Schmidtmann, I., Boutin, T., Kang, J. H., Lucas, S. E. M., Wong, T. Y., Beutel, M. E., Wilson, J. F., Allingham, R. R., Brilliant, M. H., Budenz, D. L., Christen, W. G., Fingert, J., Friedman, D. S., Gaasterland, D., Gaasterland, T., Hauser, M. A., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Loomis, S. J., Moroi, S. E., Pericak-Vance, M. A., Realini, A., Richards, J. E., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Weinreb, R. N., Wollstein, G., Zack, D. J., Zhang, K., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Uitterlinden, A. G., Vithana, E. N., Foster, P. J., Hysi, P. G., Hewitt, A. W., Khor, C. C., Pasquale, L. R., Montgomery, G. W., Klaver, C. C. W., Aung, T., Pfeiffer, N., MacKey, D. A., Hammond, C. J., Cheng, C. Y., Craig, J. E., Rabinowitz, Y. S., Wiggs, J. L., Burdon, K. P., Van Duijn, C. M. & MacGregor, S., Dec 1 2018, In : Nature Communications. 9, 1, 1864.

Research output: Contribution to journalArticle

eye diseases
Eye Diseases
genome
Genome-Wide Association Study
Keratoconus

Evaluating Self-Refraction and Ready-Made Spectacles for Treatment of Uncorrected Refractive Error

Camp, A. S., Shane, T. S., Kang, J., Thomas, B., Pole, C. & Lee, R. K., Jan 1 2018, (Accepted/In press) In : Ophthalmic Epidemiology.

Research output: Contribution to journalArticle

Refractive Errors
Visual Acuity
Spectinomycin
Therapeutics
Equipment and Supplies
1 Citation (Scopus)

Family-based genome-wide association study of south Indian pedigrees supports WNT7B as a central corneal thickness locus

Fan, B. J., Chen, X., Sondhi, N., Sharmila, P. F., Soumittra, N., Sripriya, S., Sacikala, S., Asokan, R., Friedman, D. S., Pasquale, L. R., Gao, X. R., Vijaya, L., Bailey, J. C., Vitart, V., Macgregor, S., Hammond, C. J., Khor, C. C., Haines, J. L., George, R., Wiggs, J. L. & 70 others, Allingham, R. R., Gao, X. R., Gauderman, J., Hauser, M., Rotter, J. I., Varma, R., Wiggs, J., Aung, T., Burdon, K. P., Cheng, C. Y., Craig, J. E., Cree, A. J., Gharahkhani, P., Hewitt, A. W., Höhn, R., Hysi, P., Iglesias Gonzalez, A. I., Jonas, J., Khawaja, A., Khor, C. C., Klaver, C. C. W., Pasutto, F., Macgregor, S., Mackey, D., Mitchell, P., Mishra, A., Pang, C., Pasquale, L. R., Pasutto, F., Springelkamp, H., Thorleifsson, G., Thorsteinsdottir, U., van Duijn, C. M., Viswanathan, A., Vitart, V., Wiggs, J. L., Wojciechowski, R., Wong, T., Young, T. L., Zeller, T., Allingham, R., Brilliant, M., Budenz, D., Bailey, J. C., Fingert, J., Gaasterland, D., Gaasterland, T., Haines, J. L., Hauser, M., Igo, R., Kang, J. H., Kraft, P., Lee, R., Lichter, P., Liu, Y., Moroi, S., Pasquale, L. R., Realini, A., Rhee, D., Richards, J. R., Ritch, R., Schuman, J., Scott, W. K., Singh, K., Sit, A., Vollrath, D., Weinreb, R. N., Wiggs, J. L., Wollstein, G. & Zack, D., May 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2495-2502 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pedigree
Single Nucleotide Polymorphism
Hispanic Americans
Population
4 Citations (Scopus)

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

International Glaucoma Genetics Consortium & NEIGHBORHOOD Consortium, Jan 1 2018, In : PLoS Genetics. 14, 1, e1007145.

Research output: Contribution to journalArticle

glaucoma
Glaucoma
genomics
risk factor
Quantitative Trait Loci
1 Citation (Scopus)

Phospholipid secretions of organ cultured ciliary body

Margolis, M. J., Martinez, M., Valencia, J., Lee, R. K. & Bhattacharya, S. K., Mar 1 2018, In : Journal of Cellular Biochemistry. 119, 3, p. 2556-2566 11 p.

Research output: Contribution to journalArticle

Ciliary Body
Aqueous Humor
Phospholipids
Intraocular Pressure
Timolol

Recent Advances in the Surgical Management of Glaucoma in Exfoliation Syndrome

Sayed, M. S. & Lee, R. K., Jul 1 2018, In : Journal of glaucoma. 27, p. S95-S101

Research output: Contribution to journalArticle

Exfoliation Syndrome
Glaucoma
Trabeculectomy
Glaucoma Drainage Implants
Developed Countries
2 Citations (Scopus)

Testosterone pathway genetic polymorphisms in relation to primary open-angle glaucoma: An analysis in two large datasets

Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium, Feb 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 2, p. 629-636 8 p.

Research output: Contribution to journalArticle

Genetic Polymorphisms
Testosterone
Genes
Single Nucleotide Polymorphism
Low Tension Glaucoma
2017
2 Citations (Scopus)

Differences in Optical Coherence Tomography Assessment of Bruch Membrane Opening Compared to Stereoscopic Photography for Estimating Cup-to-Disc Ratio

Mwanza, J. C., Huang, L. Y., Budenz, D. L., Shi, W., Huang, G. & Lee, R. K., Dec 1 2017, In : American Journal of Ophthalmology. 184, p. 34-41 8 p.

Research output: Contribution to journalArticle

Bruch Membrane
Photography
Optical Coherence Tomography
Reading
Optic Disk
29 Citations (Scopus)

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Aung, T., Ozaki, M., Lee, M. C., Schlötzer-Schrehardt, U., Thorleifsson, G., Mizoguchi, T., Igo, R. P., Haripriya, A., Williams, S. E., Astakhov, Y. S., Orr, A. C., Burdon, K. P., Nakano, S., Mori, K., Abu-Amero, K., Hauser, M., Li, Z., Prakadeeswari, G., Bailey, J. N. C., Cherecheanu, A. P. & 269 others, Kang, J. H., Nelson, S., Hayashi, K., Manabe, S. I., Kazama, S., Zarnowski, T., Inoue, K., Irkec, M., Coca-Prados, M., Sugiyama, K., Järvelä, I., Schlottmann, P., Lerner, S. F., Lamari, H., Nilgün, Y., Bikbov, M., Park, K. H., Cha, S. C., Yamashiro, K., Zenteno, J. C., Jonas, J. B., Kumar, R. S., Perera, S. A., Chan, A. S. Y., Kobakhidze, N., George, R., Vijaya, L., Do, T., Edward, D. P., De Juan Marcos, L., Pakravan, M., Moghimi, S., Ideta, R., Bach-Holm, D., Kappelgaard, P., Wirostko, B., Thomas, S., Gaston, D., Bedard, K., Greer, W. L., Yang, Z., Chen, X., Huang, L., Sang, J., Jia, H., Jia, L., Qiao, C., Zhang, H., Liu, X., Zhao, B., Wang, Y. X., Xu, L., Leruez, S., Reynier, P., Chichua, G., Tabagari, S., Uebe, S., Zenkel, M., Berner, D., Mossböck, G., Weisschuh, N., Hoja, U., Welge-Luessen, U. C., Mardin, C., Founti, P., Chatzikyriakidou, A., Pappas, T., Anastasopoulos, E., Lambropoulos, A., Ghosh, A., Shetty, R., Porporato, N., Saravanan, V., Venkatesh, R., Shivkumar, C., Kalpana, N., Sarangapani, S., Kanavi, M. R., Beni, A. N., Yazdani, S., Lashay, A., Naderifar, H., Khatibi, N., Fea, A., Lavia, C., Dallorto, L., Rolle, T., Frezzotti, P., Paoli, D., Salvi, E., Manunta, P., Mori, Y., Miyata, K., Higashide, T., Chihara, E., Ishiko, S., Yoshida, A., Yanagi, M., Kiuchi, Y., Ohashi, T., Sakurai, T., Sugimoto, T., Chuman, H., Aihara, M., Inatani, M., Miyake, M., Gotoh, N., Matsuda, F., Yoshimura, N., Ikeda, Y., Ueno, M., Sotozono, C., Jeoung, J. W., Sagong, M., Park, K. H., Ahn, J., Cruz-Aguilar, M., Ezzouhairi, S. M., Rafei, A., Chong, Y. F., Ng, X. Y., Goh, S. R., Chen, Y., Yong, V. H. K., Khan, M. I., Olawoye, O. O., Ashaye, A. O., Ugbede, I., Onakoya, A., Kizor-Akaraiwe, N., Teekhasaenee, C., Suwan, Y., Supakontanasan, W., Okeke, S., Uche, N. J., Asimadu, I., Ayub, H., Akhtar, F., Kosior-Jarecka, E., Lukasik, U., Lischinsky, I., Castro, V., Grossmann, R. P., Megevand, G. S., Roy, S., Dervan, E., Silke, E., Rao, A., Sahay, P., Fornero, P., Cuello, O., Sivori, D., Zompa, T., Mills, R. A., Souzeau, E., Mitchell, P., Wang, J. J., Hewitt, A. W., Coote, M., Crowston, J. G., Astakhov, S. Y., Akopov, E. L., Emelyanov, A., Vysochinskaya, V., Kazakbaeva, G., Fayzrakhmanov, R., Al-Obeidan, S. A., Owaidhah, O., Aljasim, L. A., Chowbay, B., Foo, J. N., Soh, R. Q., Sim, K. S., Xie, Z., Cheong, A. W. O., Mok, S. Q., Soo, H. M., Chen, X. Y., Peh, S. Q., Heng, K. K., Husain, R., Ho, S. L., Hillmer, A. M., Cheng, C. Y., Escudero-Domínguez, F. A., González-Sarmiento, R., Martinon-Torres, F., Salas, A., Pathanapitoon, K., Hansapinyo, L., Wanichwecharugruang, B., Kitnarong, N., Sakuntabhai, A., Nguyn, H. X., Nguyn, G. T. T., Nguyn, T. V., Zenz, W., Binder, A., Klobassa, D. S., Hibberd, M. L., Davila, S., Herms, S., Nöthen, M. M., Moebus, S., Rautenbach, R. M., Ziskind, A., Carmichael, T. R., Ramsay, M., Álvarez, L., García, M., González-Iglesias, H., Rodríguez-Calvo, P. P., Cueto, L. F. V., Oguz, Ç., Tamcelik, N., Atalay, E., Batu, B., Aktas, D., Kaslm, B., Wilson, M. R., Coleman, A. L., Liu, Y., Challa, P., Herndon, L., Kuchtey, R. W., Kuchtey, J., Curtin, K., Chaya, C. J., Crandall, A., Zangwill, L. M., Wong, T. Y., Nakano, M., Kinoshita, S., Den Hollander, A. I., Vesti, E., Fingert, J. H., Lee, R. K., Sit, A. J., Shingleton, B. J., Wang, N., Cusi, D., Qamar, R., Kraft, P., Pericak-Vance, M. A., Raychaudhuri, S., Heegaard, S., Kivelä, T., Reis, A., Kruse, F. E., Weinreb, R. N., Pasquale, L. R., Haines, J. L., Thorsteinsdottir, U., Jonasson, F., Allingham, R. R., Milea, D., Ritch, R., Kubota, T., Tashiro, K., Vithana, E. N., Micheal, S., Topouzis, F., Craig, J. E., Dubina, M., Sundaresan, P., Stefansson, K., Wiggs, J. L., Pasutto, F. & Khor, C. C., Jul 1 2017, In : Nature Genetics. 49, 7, p. 993-1004 12 p.

Research output: Contribution to journalArticle

Exfoliation Syndrome
Genome-Wide Association Study
Genetic Association Studies
Blindness
Glaucoma
4 Citations (Scopus)

Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: A multi-cohort analysis

Aschard, H., Kang, J. H., Iglesias, A. I., Hysi, P., Cooke Bailey, J. N., Khawaja, A. P., Allingham, R. R., Ashley-Koch, A., Lee, R. K., Moroi, S. E., Brilliant, M. H., Wollstein, G., Schuman, J. S., Fingert, J. H., Budenz, D. L., Realini, T., Gaasterland, T., Scott, W. K., Singh, K., Sit, A. J. & 25 others, Igo, R. P., Song, Y. E., Hark, L., Ritch, R., Rhee, D. J., Gulati, V., Haven, S., Vollrath, D., Zack, D. J., Medeiros, F., Weinreb, R. N., Cheng, C. Y., Chasman, D. I., Christen, W. G., Pericak-Vance, M. A., Liu, Y., Kraft, P., Richards, J. E., Rosner, B. A., Hauser, M. A., Klaver, C. C. W., Vanduijn, C. M., Haines, J., Wiggs, J. L. & Pasquale, L. R., Nov 1 2017, In : European Journal of Human Genetics. 25, 11, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Cohort Studies
Blood Pressure
Genome
Linkage Disequilibrium
6 Citations (Scopus)

Green disease in optical coherence tomography diagnosis of glaucoma

Sayed, M. S., Margolis, M. & Lee, R. K., Mar 1 2017, In : Current Opinion in Ophthalmology. 28, 2, p. 139-153 15 p.

Research output: Contribution to journalReview article

Optical Coherence Tomography
Glaucoma
Nerve Fibers
Color
Optic Disk

In Reply

Sayed, M. S. & Lee, R. K., Jan 1 2017, In : Journal of Glaucoma. 26, 11, p. e260

Research output: Contribution to journalLetter

18 Citations (Scopus)

Ocular histopathologic features of congenital Zika syndrome

Fernandez, M. P., Parra Saad, E., Ospina Martinez, M., Corchuelo, S., Mercado Reyes, M., Herrera, M. J., Parra Saavedra, M., Rico, A., Fernandez, A. M., Lee, R. K., Ventura, C. V., Berrocal, A. & Dubovy, S., Nov 1 2017, In : JAMA Ophthalmology. 135, 11, p. 1163-1169 7 p.

Research output: Contribution to journalArticle

Choroid
Optic Nerve
Retinal Pigment Epithelium
Retina
Fetus
1 Citation (Scopus)

Rapid Intraocular Tube Trimming for Glaucoma Drainage Implant Devices

Baciu, P., Moster, S. J. & Lee, R. K., 2017, In : Journal of Glaucoma. 26, 5, p. e174-e176

Research output: Contribution to journalArticle

Glaucoma Drainage Implants
Glaucoma
Drainage
Equipment and Supplies
Silicones
4 Citations (Scopus)

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

Chintalapudi, S. R., Maria, D., Di Wang, X., Bailey, J. N. C., Allingham, R., Brilliant, M., Budenz, D., Fingert, J., Gaasterland, D., Gaasterland, T., Haines, J. L., Hark, L., Hauser, M., Igo, R., Hee Kang, J., Kraft, P., Lee, R. K., Lichter, P., Liu, Y., Moroi, S. & 43 others, Pasquale, L. R., Pericak-Vance, M. A., Realini, A., Rhee, D., Richards, J. R., Ritch, R., Schuman, J., Scott, W. K., Singh, K., Sit, A., Vollrath, D., Wollstein, G., Zack, D., Aung, T., Bonnemaijer, P., Cheng, C. Y., Craig, J., Van Duijn, C., Gharahkhani, P., Iglesias Gonzalez, A., Hammond, C. J., Hewitt, A., Hoehn, R., Jonansson, F., Khawaja, A., Chuen Khor, C., Klaver, C. C. W., Lotery, A., MacKey, D., MacGregor, S., Pang, C., Pasutto, F., Stefansson, K., Thorleifsson, G., Thorsteinsdottir, U., Vitart, V., Vithana, E., Young, T., Zeller, T., Hysi, P. G., Wiggs, J. L., Williams, R. W. & Jablonski, M. M., Dec 1 2017, In : Nature Communications. 8, 1, 1755.

Research output: Contribution to journalArticle

intraocular pressure
glaucoma
Intraocular Pressure
Glaucoma
magnetic permeability
2016
13 Citations (Scopus)

A common variant in MIR182 is associated with primary open-angle glaucoma in the NEIGHBORHOOD consortium

Liu, Y., Bailey, J. C., Helwa, I., Dismuke, W. M., Cai, J., Drewry, M., Brilliant, M. H., Budenz, D. L., Christen, W. G., Chasman, D. I., Fingert, J. H., Gaasterland, D., Gaasterland, T., Gordon, M. O., Igo, R. P., Kang, J. H., Kass, M. A., Kraft, P., Lee, R. K., Lichter, P. & 25 others, Moroi, S. E., Realini, A., Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Song, Y. E., Vollrath, D., Weinreb, R., Medeiros, F., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M. A., Gonzalez, P., Stamer, W. D., Kuchtey, J., Kuchtey, R. W., Allingham, R. R., Hauser, M. A., Pasquale, L. R., Haines, J. L. & Wiggs, J. L., Aug 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 10, p. 4528-4535 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Trabecular Meshwork
Glaucoma
Aqueous Humor
Exosomes
2 Citations (Scopus)

Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample

Pasquale, L. R., Aschard, H., Kang, J. H., Bailey, J. N. C., Lindström, S., Chasman, D. I., Christen, W. G., Allingham, R. R., Ashley-Koch, A., Lee, R. K., Moroi, S. E., Brilliant, M. H., Wollstein, G., Schuman, J. S., Fingert, J., Budenz, D. L., Realini, T., Gaasterland, T., Gaasterland, D., Scott, W. K. & 21 others, Singh, K., Sit, A. J., Igo, R. P., Song, Y. E., Hark, L., Ritch, R., Rhee, D. J., Gulati, V., Havens, S., Vollrath, D., Zack, D. J., Medeiros, F., Weinreb, R. N., Pericak-Vance, M. A., Liu, Y., Kraft, P., Richards, J. E., Rosner, B. A., Hauser, M. A., Haines, J. L. & Wiggs, J. L., Oct 10 2016, (Accepted/In press) In : Menopause.

Research output: Contribution to journalArticle

Menopause
Odds Ratio
Confidence Intervals
Licensure
National Eye Institute (U.S.)

Anterior segment trauma

Lee, R. K. & Sayed, M. S., Jan 1 2016, Mechanical Ocular Trauma: Current Consensus and Controversy. Springer Singapore, p. 7-38 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Wounds and Injuries
Limbus Corneae
Ciliary Body
Conjunctiva
Anterior Chamber
13 Citations (Scopus)

Assessing the association of mitochondrial genetic variation with primary open-angle glaucoma using gene-set analyses

Khawaja, A. P., Cooke Bailey, J. N., Kang, J. H., Rand Allingham, R., Hauser, M. A., Brilliant, M., Budenz, D. L., Christen, W. G., Fingert, J., Gaasterland, D., Gaasterland, T., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Medeiros, F., Moroi, S. E., Richards, J. E., Realini, T., Ritch, R. & 13 others, Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M. A., Weinreb, R. N., Haines, J. L., Pasquale, L. R. & Wiggs, J. L., Sep 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 11, p. 5046-5052 7 p.

Research output: Contribution to journalArticle

Low Tension Glaucoma
Mitochondrial Proteins
Encyclopedias
Genes
Carbohydrate Metabolism
15 Citations (Scopus)

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium

eMERGE Network & NEIGHBOR Consortium, Sep 1 2016, In : PLoS Genetics. 12, 9, e1006186.

Research output: Contribution to journalArticle

Genetic Epistasis
glaucoma
Electronic Health Records
epistasis
Genomics
7 Citations (Scopus)

Genetic networks in mouse retinal ganglion cells

Struebing, F. L., Lee, R. K., Williams, R. W. & Geisert, E. E., Sep 28 2016, In : Frontiers in Genetics. 7, SEP, 169.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Gene Regulatory Networks
Glaucoma
Optic Nerve Injuries
Inbred Strains Mice
91 Citations (Scopus)

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

Bailey, J. N. C., Loomis, S. J., Kang, J. H., Allingham, R. R., Gharahkhani, P., Khor, C. C., Burdon, K. P., Aschard, H., Chasman, D. I., Igo, R. P., Hysi, P. G., Glastonbury, C. A., Ashley-Koch, A., Brilliant, M., Brown, A. A., Budenz, D. L., Buil, A., Cheng, C. Y., Choi, H., Christen, W. G. & 60 others, Curhan, G., De Vivo, I., Fingert, J. H., Foster, P. J., Fuchs, C., Gaasterland, D., Gaasterland, T., Hewitt, A. W., Hu, F., Hunter, D. J., Khawaja, A. P., Lee, R. K., Li, Z., Lichter, P. R., Mackey, D. A., McGuffin, P., Mitchell, P., Moroi, S. E., Perera, S. A., Pepper, K. W., Qi, Q., Realini, T., Richards, J. E., Ridker, P. M., Rimm, E., Ritch, R., Ritchie, M., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Song, Y. E., Tamimi, R. M., Topouzis, F., Viswanathan, A. C., Verma, S. S., Vollrath, D., Wang, J. J., Weisschuh, N., Wissinger, B., Wollstein, G., Wong, T. Y., Yaspan, B. L., Zack, D. J., Zhang, K., Weinreb, R. N., Pericak-Vance, M. A., Small, K., Hammond, C. J., Aung, T., Liu, Y., Vithana, E. N., MacGregor, S., Craig, J. E., Kraft, P., Howell, G., Hauser, M. A., Pasquale, L. R., Haines, J. L. & Wiggs, J. L., Feb 1 2016, In : Nature Genetics. 48, 2, p. 189-194 6 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Odds Ratio
Single Nucleotide Polymorphism
Meta-Analysis
Retinal Ganglion Cells

Glaucomas: Pseudoexfoliation glaucoma

Lee, R. K., Jan 1 2016, Pearls of Glaucoma Management: Second Edition. Springer Berlin Heidelberg, p. 411-418 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

17 Citations (Scopus)

Long-term outcomes of neovascular glaucoma treated with and without intravitreal bevacizumab

Olmos, L. C., Sayed, M. S., Moraczewski, A. L., Gedde, S. J., Rosenfeld, P. J., Shi, W., Feuer, W. J. & Lee, R. K., Mar 1 2016, In : Eye (Basingstoke). 30, 3, p. 463-472 10 p.

Research output: Contribution to journalArticle

Neovascular Glaucoma
Intraocular Pressure
Visual Acuity
Fingers
Light Coagulation
1 Citation (Scopus)

Neuro-rejuvenation for neuronal function

Liu, Y. & Lee, R. K., Oct 1 2016, In : Neural Regeneration Research. 11, 10, p. 1560-1563 4 p.

Research output: Contribution to journalReview article

Rejuvenation
Neurodegenerative Diseases
Regeneration
Eye Diseases
Medical Economics

Procedural treatments: Bleb needling

JoAnn, G. & Lee, R. K., Jan 1 2016, Pearls of Glaucoma Management: Second Edition. Springer Berlin Heidelberg, p. 339-347 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Reply to 'Comment on: Long-term outcomes of neovascular glaucoma treated with and without intravitreal bevacizumab'

Olmos, L. C., Sayed, M. S. & Lee, R. K., Jun 1 2016, In : Eye (Basingstoke). 30, 6, p. 897-898 2 p.

Research output: Contribution to journalLetter

Neovascular Glaucoma
Bevacizumab
1 Citation (Scopus)

Treatment of Recalcitrant Cyclitic Neovascular Pupillary Membranes

Spratt, A., Blieden, L. S., Dubovy, S., Berrocal, A. & Lee, R. K., Aug 26 2016, (Accepted/In press) In : Journal of Glaucoma.

Research output: Contribution to journalArticle

Retinal Diseases
Aptitude
Membranes
Lasers
Therapeutics
2015
5 Citations (Scopus)

Current management approaches for uveitic glaucoma

Sayed, M. S. & Lee, R. K., Jul 9 2015, In : International Ophthalmology Clinics. 55, 3, p. 141-160 20 p.

Research output: Contribution to journalArticle

Ophthalmologic Surgical Procedures
Glaucoma Drainage Implants
Mydriatics
Ocular Hypertension
Uveitis
31 Citations (Scopus)

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

NEIGHBORHOOD Consortium, Mar 1 2015, In : Genetic Epidemiology. 39, 3, p. 207-216 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Optic Disk
Glaucoma
Meta-Analysis
Optic Nerve Diseases
7 Citations (Scopus)

Prevalence and risk factors of primary open-angle glaucoma in a city of Eastern China: A population-based study in Pudong New District, Shanghai

He, J., Zou, H., Lee, R. K., Tong, X., Tang, W., Zhang, Y., Zhao, R. & Ge, L., Oct 13 2015, In : BMC Ophthalmology. 15, 1, 134.

Research output: Contribution to journalArticle

China
Population
Intraocular Pressure
Gonioscopy
Primary Open Angle Glaucoma
33 Citations (Scopus)

Residual and dynamic range of retinal nerve fiber layer thickness in glaucoma: Comparison of three OCT platforms

Mwanza, J. C., Kim, H. Y., Budenz, D. L., Warren, J. L., Margolis, M., Lawrence, S. D., Jani, P. D., Thompson, G. S. & Lee, R. K., 2015, In : Investigative Ophthalmology and Visual Science. 56, 11, p. 6344-6351 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Nerve Fibers
Glaucoma
Visual Fields
Linear Models
2014
48 Citations (Scopus)

Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss

Loomis, S. J., Kang, J. H., Weinreb, R. N., Yaspan, B. L., Cooke Bailey, J. N., Gaasterland, D., Gaasterland, T., Lee, R. K., Lichter, P. R., Budenz, D. L., Liu, Y., Realini, T., Friedman, D. S., McCarty, C. A., Moroi, S. E., Olson, L., Schuman, J. S., Singh, K., Vollrath, D., Wollstein, G. & 14 others, Zack, D. J., Brilliant, M., Sit, A. J., Christen, W. G., Fingert, J., Kraft, P., Zhang, K., Allingham, R. R., Pericak-Vance, M. A., Richards, J. E., Hauser, M. A., Haines, J. L., Pasquale, L. R. & Wiggs, J. L., Feb 1 2014, In : Ophthalmology. 121, 2, p. 508-516 9 p.

Research output: Contribution to journalArticle

Caveolin 2
Caveolin 1
Visual Fields
Single Nucleotide Polymorphism
Glaucoma
60 Citations (Scopus)

Diagnostic performance of optical coherence tomography ganglion cell-inner plexiform layer thickness measurements in early glaucoma

Mwanza, J. C., Budenz, D. L., Godfrey, D. G., Neelakantan, A., Sayyad, F. E., Chang, R. T. & Lee, R. K., Jan 1 2014, In : Ophthalmology. 121, 4, p. 849-854 6 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Nerve Fibers
Ganglia
Glaucoma
Optic Disk
45 Citations (Scopus)

Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma

Ulmer Carnes, M., Liu, Y. P., Allingham, R. R., Whigham, B. T., Havens, S., Garrett, M. E., Qiao, C., Katsanis, N., Wiggs, J. L., Pasquale, L. R., Ashley-Koch, A., Oh, E. C., Hauser, M. A., Allingham, R. R., Brilliant, M., Budenz, D. L., Chin, H. R., Cooke Bailey, J., Fingert, J., Friedman, D. S. & 26 others, Gaasterland, D., Gaasterland, T., Haines, J., Hauser, M. A., Lee, R. K., Lee, R. K., Lichter, P. R., Liu, Y., Loomis, S., McCarty, C. E., Moroi, S. E., Pericak-Vance, M. A., Pericak-Vance, M., Realini, A., Richards, J. E., Scott, W. K., Scott, W. K., Singh, K., Sit, A., Vollrath, D., Weinreb, R. N., Wiggs, J. L., Wollstein, G., Yaspan, B. L., Zack, D. & Zhang, K., Jan 1 2014, In : PLoS Genetics. 10, 5, e1004372.

Research output: Contribution to journalArticle

glaucoma
allele
blindness
Zebrafish
Optic Nerve
14 Citations (Scopus)

DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma

Liu, Y., Garrett, M. E., Yaspan, B. L., Bailey, J. C., Loomis, S. J., Brilliant, M., Budenz, D. L., Christen, W. G., Fingert, J. H., Gaasterland, D., Gaasterland, T., Kang, J. H., Lee, R. K., Lichter, P., Moroi, S. E., Realini, A., Richards, J. E., Schuman, J. S., Scott, W. K., Singh, K. & 13 others, Sit, A. J., Vollrath, D., Weinreb, R., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M. A., Haines, J. L., Pasquale, L. R., Wiggs, J. L., Allingham, R. R., Ashley-Koch, A. E. & Hauser, M. A., Nov 20 2014, In : Investigative Ophthalmology and Visual Science. 55, 12, p. 8251-8258 8 p.

Research output: Contribution to journalArticle

DNA Copy Number Variations
Glaucoma
Genes
DNA
Gene Frequency
107 Citations (Scopus)

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

NEIGHBORHOOD Consortium, BMES GWAS Group & Wellcome Trust Case Control Consortium 2, Jan 1 2014, In : Nature Genetics. 46, 10, p. 1126-1130 5 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Glaucoma
Genome
Meta-Analysis
Chromosomes
5 Citations (Scopus)

Genomic and proteomic pathophysiology of pseudoexfoliation glaucoma

Vazquez, L. E. & Lee, R. K., 2014, In : International Ophthalmology Clinics. 54, 4, p. 1-13 13 p.

Research output: Contribution to journalArticle

Eye Proteins
Exfoliation Syndrome
Proteome
Genetic Predisposition to Disease
Glaucoma
8 Citations (Scopus)

Glaucoma screening in the Haitian Afro-Caribbean population of South Florida

Bokman, C. L., Pasquale, L. R., Parrish, R. K. & Lee, R. K., Dec 30 2014, In : PLoS One. 9, 12, e115942.

Research output: Contribution to journalArticle

glaucoma
Glaucoma
Screening
eyes
screening
8 Citations (Scopus)

Human trabecular meshwork sphingolipid and ceramide profiles and potential latent fungal commensalism

Aljohani, A. J., Edwards, G., Guerra, Y., Dubovy, S., Miller, D., Lee, R. K. & Bhattacharya, S. K., May 1 2014, In : Investigative Ophthalmology and Visual Science. 55, 6, p. 3413-3422 10 p.

Research output: Contribution to journalArticle

Trabecular Meshwork
Sphingolipids
Symbiosis
Ceramides
Fusarium
12 Citations (Scopus)

Hypothesis-independent pathway analysis implicates GABA and Acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma

Bailey, J. N. C., Yaspan, B. L., Pasquale, L. R., Hauser, M. A., Kang, J. H., Loomis, S. J., Brilliant, M., Budenz, D. L., Christen, W. G., Fingert, J., Gaasterland, D., Gaasterland, T., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., McCarty, C. A., Moroi, S. E., Richards, J. E., Realini, T. & 13 others, Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M. A., Allingham, R. R., Weinreb, R. N., Haines, J. L. & Wiggs, J. L., Jul 19 2014, (Accepted/In press) In : Human Genetics.

Research output: Contribution to journalArticle

Acetyl Coenzyme A
Glaucoma
gamma-Aminobutyric Acid
Pressure
National Eye Institute (U.S.)
50 Citations (Scopus)

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

Blue Mountains Eye Study-GWAS groupw, NEIGHBORHOOD Consortiumz, Wellcome Trust Case Control Consortium 2 (WTCCC2), Data and Analysis Group, DNA, Genotyping, Data QC and Informatics Group & Publications Committee, 2014, In : Nature Communications. 5, 4883.

Research output: Contribution to journalArticle

glaucoma
genome
Genome-Wide Association Study
loci
Glaucoma
15 Citations (Scopus)

Nerve fiber layer thinning lags retinal ganglion cell density following crush axonopathy

Munguba, G. C., Galeb, S., Liu, Y., Landy, D. C., Lam, D., Camp, A., Samad, S., Tapia, M. L. & Lee, R. K., Jan 1 2014, In : Investigative Ophthalmology and Visual Science. 55, 10, p. 6505-6513 9 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Nerve Fibers
Carisoprodol
Ophthalmoscopy
Cell Count
Exfoliation Syndrome
Glaucoma
Proteomics