Ramiro E Verdun

Associate Professor

  • 1922 Citations
19982020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 1922 Citations
  • 30 Article
  • 1 Review article
2020

Estrogen induces dynamic ERα and RING1B recruitment to control gene and enhancer activities in luminal breast cancer

Zhang, Y., Zhang, Y., Chan, H. L., Chan, H. L., Garcia-Martinez, L., Garcia-Martinez, L., Karl, D. L., Weich, N., Weich, N., Slingerland, J. M., Slingerland, J. M., Slingerland, J. M., Slingerland, J. M., Verdun, R. E., Verdun, R. E., Morey, L. & Morey, L., Jun 2020, In : Science Advances. 6, 23, EAAZ7249.

Research output: Contribution to journalArticle

Open Access

Recent BCR stimulation induces a negative autoregulatory loop via FBXO10 mediated degradation of HGAL

Guo, F., Luo, Y., Jiang, X., Lu, X. Q., Roberti, D., Lossos, C., Kunkalla, K., Magistri, M., Rui, L., Verdun, R., Vega, F., Moy, V. T. & Lossos, I. S., Feb 1 2020, In : Leukemia. 34, 2, p. 553-566 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling

Jiang, X., Lu, X., Zhang, Y., Lacaria, L., Schuchardt, B. J., Mikles, D. C., Magistri, M., García-Ramírez, I., Sanchez-Garcia, I., Farooq, A., Verdun, R. E., Abdulreda, M. H., Moy, V. T. & Lossos, I. S., Aug 13 2019, In : Blood Advances. 3, 15, p. 2286-2297 12 p.

Research output: Contribution to journalArticle

Open Access

LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL

Parvin, S., Ramirez-Labrada, A., Aumann, S., Lu, X. Q., Weich, N., Santiago, G., Cortizas, E. M., Sharabi, E., Zhang, Y., Sanchez-Garcia, I., Gentles, A. J., Roberts, E., Bilbao-Cortes, D., Vega, F., Chapman, J. R., Verdun, R. E. & Lossos, I. S., Sep 16 2019, In : Cancer Cell. 36, 3, p. 237-249.e6

Research output: Contribution to journalArticle

6 Scopus citations
2018

A licensing step links AID to transcription elongation for mutagenesis in B cells

Methot, S. P., Litzler, L. C., Subramani, P. G., Eranki, A. K., Fifield, H., Patenaude, A. M., Gilmore, J. C., Santiago, G. E., Bagci, H., Côté, J. F., Larijani, M., Verdun, R. E. & Di Noia, J. M., Dec 1 2018, In : Nature Communications. 9, 1, 1248.

Research output: Contribution to journalArticle

6 Scopus citations

PRMT5 Regulates DNA Repair by Controlling the Alternative Splicing of Histone-Modifying Enzymes

Hamard, P. J., Santiago, G. E., Liu, F., Karl, D. L., Martinez, C., Man, N., Mookhtiar, A. K., Duffort, S., Greenblatt, S., Verdun, R. E. & Nimer, S. D., Sep 4 2018, In : Cell Reports. 24, 10, p. 2643-2657 15 p.

Research output: Contribution to journalArticle

28 Scopus citations
2017

Epstein-Barr virus-positive follicular lymphoma

Mackrides, N., Campuzano-Zuluaga, G., Maque-Acosta, Y., Moul, A., Hijazi, N., Ikpatt, F. O., Levy, R., Verdun, R. E., Kunkalla, K., Natkunam, Y., Lossos, I. S., Vega, F. & Chapman, J., Apr 1 2017, In : Modern Pathology. 30, 4, p. 519-529 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

Active IKKb promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma

Agarwal, N. K., Kim, C. H., Kunkalla, K., Konno, H., Tjendra, Y., Kwon, D., Blonska, M., Kozloski, G. A., Moy, V. T., Verdun, R. E., Barber, G. N., Lossos, I. S. & Vega, F., Feb 4 2016, In : Blood. 127, 5, p. 605-615 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Class-switch recombination in the absence of the igh 39 regulatory region

Kim, A., Han, L., Santiago, G. E., Verdun, R. E. & Yu, K., Oct 1 2016, In : Journal of Immunology. 197, 7, p. 2930-2935 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms

Asai, T., Hatlen, M. A., Lossos, C., Ndiaye-Lobry, D., Deblasio, A., Murata, K., Fleisher, M., Cortizas, E. M., Verdun, R. E., Petrini, J. & Nimer, S. D., Mar 10 2016, In : Scientific Reports. 6, 22760.

Research output: Contribution to journalArticle

3 Scopus citations

Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma

Matthews, J. M., Bhatt, S., Patricelli, M. P., Nomanbhoy, T. K., Jiang, X., Natkunam, Y., Gentles, A. J., Martinez, E., Zhu, D., Chapman, J. R., Cortizas, E., Shyam, R., Chinichian, S., Advani, R., Tan, L., Zhang, J., Choi, H. G., Tibshirani, R., Buhrlage, S. J., Gratzinger, D. & 3 others, Verdun, R., Gray, N. S. & Lossos, I. S., Jul 14 2016, In : Blood. 128, 2, p. 239-248 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

The microRNA-23b/-27b cluster suppresses prostate cancer metastasis via Huntingtin-interacting protein 1-related

Rice, M. A., Ishteiwy, R. A., Magani, F., Udayakumar, T., Reiner, T., Yates, T. J., Miller, P., Perez-Stable, C., Rai, P., Verdun, R., Dykxhoorn, D. M. & Burnstein, K. L., Sep 8 2016, In : Oncogene. 35, 36, p. 4752-4761 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

UNG protects B cells from AID-induced telomere loss

Cortizas, E. M., Zahn, A., Safavi, S., Reed, J. A., Vega, F., Di Noia, J. M. & Verdun, R. E., Oct 17 2016, In : Journal of Experimental Medicine. 213, 11, p. 2459-2472 14 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations
2015

Cyclin-dependent kinases regulate Ig class switching by controlling access of AID to the switch region

He, M., Cortizas, E. M., Verdun, R. E. & Severinson, E., May 1 2015, In : Journal of Immunology. 194, 9, p. 4231-4239 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination

Zahn, A., Eranki, A. K., Patenaude, A. M., Methot, S. P., Fifield, H., Cortizas, E. M., Foster, P., Imai, K., Durandy, A., Larijani, M., Verdun, R. E. & Di Noia, J. M., Mar 18 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 11, p. E988-E997

Research output: Contribution to journalArticle

34 Scopus citations

A novel mouse model for the hyper-IgM syndrome: A spontaneous activation-induced cytidine deaminase mutation leading to complete loss of Ig class switching and reduced somatic hypermutation

Dahlberg, C. I. M., He, M., Visnes, T., Torres, M. L., Cortizas, E. M., Verdun, R. E., Westerberg, L. S., Severinson, E. & Ström, L., Nov 1 2014, In : Journal of Immunology. 193, 9, p. 4732-4738 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2013

Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination

Cortizas, E. M., Zahn, A., Hajjar, M. E., Patenaude, A. M., Di Noia, J. M. & Verdun, R. E., Dec 1 2013, In : Journal of Immunology. 191, 11, p. 5751-5763 13 p.

Research output: Contribution to journalArticle

31 Scopus citations
2012

Severe heat shock induces nucleolar accumulation of mRNAs in Trypanosoma cruzi

Názer, E., Verdún, R. E. & Sánchez, D. O., Aug 27 2012, In : PloS one. 7, 8, e43715.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Nucleolar localization of RNA binding proteins induced by Actinomycin D and heat shock in Trypanosoma cruzi

Názer, E., Verdún, R. E. & Sánchez, D. O., 2011, In : PloS one. 6, 5, e19920.

Research output: Contribution to journalArticle

17 Scopus citations
2008

C. elegans Telomeres Contain G-Strand and C-Strand Overhangs that Are Bound by Distinct Proteins

Raices, M., Verdun, R. E., Compton, S. A., Haggblom, C. I., Griffith, J. D., Dillin, A. & Karlseder, J., Mar 7 2008, In : Cell. 132, 5, p. 745-757 13 p.

Research output: Contribution to journalArticle

72 Scopus citations
2007

Replication and protection of telomeres

Verdun, R. E. & Karlseder, J., Jun 21 2007, In : Nature. 447, 7147, p. 924-931 8 p.

Research output: Contribution to journalReview article

351 Scopus citations
2006

The DNA Damage Machinery and Homologous Recombination Pathway Act Consecutively to Protect Human Telomeres

Verdun, R. E. & Karlseder, J., Nov 17 2006, In : Cell. 127, 4, p. 709-720 12 p.

Research output: Contribution to journalArticle

250 Scopus citations
2005

Functional human telomeres are recognized as DNA damage in G2 of the cell cycle

Verdun, R. E., Crabbe, L., Haggblom, C. & Karlseder, J., Nov 23 2005, In : Molecular Cell. 20, 4, p. 551-561 11 p.

Research output: Contribution to journalArticle

218 Scopus citations
2004

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity

Crabbe, L., Verdun, R. E., Haggblom, C. I. & Karlseder, J., Dec 10 2004, In : Science. 306, 5703, p. 1951-1953 3 p.

Research output: Contribution to journalArticle

448 Scopus citations
2003

p53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage

Espinosa, J. M., Verdun, R. E. & Emerson, B. M., Oct 2003, In : Molecular Cell. 12, 4, p. 1015-1027 13 p.

Research output: Contribution to journalArticle

204 Scopus citations
2001

Gene discovery through genomic sequencing of brucella abortus

Sánchez, D. O., Zandomeni, R. O., Cravero, S., Verdún, R. E., Pierrou, E., Faccio, P., Diaz, G., Lanzavecchia, S., Agüero, F., Frasch, A. C. C., Andersson, S. G. E., Rossetti, O. L., Grau, O. & Ugalde, R. A., 2001, In : Infection and immunity. 69, 2, p. 865-868 4 p.

Research output: Contribution to journalArticle

33 Scopus citations
2000

A random sequencing approach for the analysis of the Trypanosoma cruzi genome: General structure, large gene and repetitive DNA families, and gene discovery

Agüero, F., Verdún, R. E., Frasch, A. C. C. & Sánchez, D. O., 2000, In : Genome Research. 10, 12, p. 1996-2005 10 p.

Research output: Contribution to journalArticle

44 Scopus citations
1999

GB virus C/hepatitis G virus groups and subgroups: Classification by a restriction fragment length polymorphism method based on phylogenetic analysis of the 5' untranslated region

Quarleri, J. F., Mathet, V. L., Feld, M., Ferrario, D., Della Latta, M. P., Verdun, R., Sánchez, D. O. & Oubiña, J. R., 1999, In : Journal of Clinical Microbiology. 37, 5, p. 1340-1347 8 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Genetic diversity of GBV-C/HGV strains among HIV infected-IVDU and blood donors from Buenos Aires, Argentina

Oubiña, J. R., Mathet, V., Feld, M., Della Latta, M. P., Ferrario, D., Verdun, R., Libonatti, O., Fernández, J., Carballal, G., Sánchez, D. O. & Quarleri, J. F., Dec 15 1999, In : Virus Research. 65, 2, p. 121-129 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Organizacion de la red para el estudio del genoma de Trypanosoma cruzi

Translated title of the contribution: Organization of the parasite genome programme networkFrasch, A. C. C., Verdun, R. E. & Sanchez, D. O., Dec 1 1999, In : Medicina. 59, SUPPL. 2, p. 4-6 3 p.

Research output: Contribution to journalArticle

1998

Gene discovery through expressed sequence tag sequencing in Trypanosoma cruzi

Verdun, R. E., Di Paolo, N., Urmenyi, T. P., Rondinelli, E., Frasch, A. C. C. & Sanchez, D. O., Dec 1 1998, In : Infection and Immunity. 66, 11, p. 5393-5398 6 p.

Research output: Contribution to journalArticle

55 Scopus citations