Ramin Shiekhattar

Professor

  • 20677 Citations
1990 …2022
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  • 2 Similar Profiles
Long Noncoding RNA Medicine & Life Sciences
Histones Medicine & Life Sciences
Chromatin Medicine & Life Sciences
RNA Polymerase II Medicine & Life Sciences
Genes Chemical Compounds
MicroRNAs Medicine & Life Sciences
Transcription Chemical Compounds
Chromatin Assembly and Disassembly Medicine & Life Sciences

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Projects 1993 2022

Enhancer RNA Therapy

Shiekhattar, R.

National Institutes of Health

9/30/177/31/22

Project: Research project

RNA
Neoplasms
Mutation
Therapeutics
MAP Kinase Signaling System
Small Nuclear RNA
RNA Polymerase II
Cleavage And Polyadenylation Specificity Factor
Genes
Proteins
Mediator Complex
Untranslated RNA
Chromatin
Transcriptional Activation
Phosphotransferases
Epigenomics
Chromatin
Untranslated RNA
Bahamas
Research

Research Output 1990 2019

  • 20677 Citations
  • 114 Article

TAF1 plays a critical role in AML1-ETO driven leukemogenesis

Xu, Y., Man, N., Karl, D., Martinez, C., Liu, F., Sun, J., Martinez, C. J., Martin, G. M., Beckedorff, F., Lai, F., Yue, J., Roisman, A., Greenblatt, S., Duffort, S., Wang, L., Sun, X., Figueroa, M., Shiekhattar, R. & Nimer, S., Dec 1 2019, In : Nature communications. 10, 1, 4925.

Research output: Contribution to journalArticle

Open Access
TATA-Binding Protein Associated Factors
TATA-Box Binding Protein
boxes
leukemias
proteins
28 Citations (Scopus)

Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

Amaral, P. P., Leonardi, T., Han, N., Viré, E., Gascoigne, D. K., Arias-Carrasco, R., Büscher, M., Pandolfini, L., Zhang, A., Pluchino, S., Maracaja-Coutinho, V., Nakaya, H. I., Hemberg, M., Shiekhattar, R., Enright, A. J. & Kouzarides, T., Mar 15 2018, In : Genome Biology. 19, 1, 32.

Research output: Contribution to journalArticle

Long Noncoding RNA
anchor
RNA
genomics
chromatin
12 Citations (Scopus)

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms

Chan, H. L., Beckedorff, F., Zhang, Y., Garcia-Huidobro, J., Jiang, H., Colaprico, A., Bilbao, D., Figueroa, M., LaCava, J., Shiekhattar, R. & Morey, LL., Dec 1 2018, In : Nature Communications. 9, 1, 3377.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 1
Genes
cancer
Cells
Triple Negative Breast Neoplasms
5 Citations (Scopus)

Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs

Yue, J., Lai, F., Beckedorff, F., Zhang, A., Pastori, C. & Shiekhattar, R., Sep 1 2017, In : Genes and Development. 31, 17, p. 1809-1820 12 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Immediate-Early Genes
Mutation
Neoplasms
Mediator Complex
11 Citations (Scopus)

Loss of p300 accelerates MDS-associated leukemogenesis

Cheng, G., Liu, F., Asai, T., Lai, F., Man, N., Xu, H., Chen, S., Greenblatt, S., Hamard, P. J., Ando, K., Chen, X., Wang, L., Martinez, C., Tadi, M., Wang, L., Xu, M., Yang, F-C., Shiekhattar, R. & Nimer, S. D., Jan 6 2017, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

CREB-Binding Protein
Myelodysplastic Syndromes
Hematopoietic Stem Cells
Histone Code
Neoplasms