Ramin Shiekhattar

Professor

  • 19177 Citations
1990 …2022
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  • 3 Similar Profiles
Long Noncoding RNA Medicine & Life Sciences
Histones Medicine & Life Sciences
RNA Polymerase II Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Genes Chemical Compounds
MicroRNAs Medicine & Life Sciences
Transcription Chemical Compounds
Chromatin Assembly and Disassembly Medicine & Life Sciences

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Projects 1993 2022

Enhancer RNA Therapy

Shiekhattar, R.

National Institutes of Health

9/30/177/31/22

Project: Research projectNIH Director’s Pioneer Award (NDPA)

RNA
Neoplasms
Mutation
Therapeutics
MAP Kinase Signaling System
Mediator Complex
Untranslated RNA
Chromatin
Transcriptional Activation
Phosphotransferases

Elucidation of Integrator's Function

Shiekhattar, R.

National Institutes of Health

8/1/1012/31/19

Project: Research projectResearch Project

Small Nuclear RNA
RNA Polymerase II
Cleavage And Polyadenylation Specificity Factor
Genes
RNA

REGULATION OF DR1-A REPRESSOR OF CLASS II TRANSCRIPTION

Shiekhattar, R.

National Institutes of Health

9/30/93 → …

Project: Research projectPostdoctoral Individual National Research Service Award

Epigenomics
Chromatin
Untranslated RNA
Bahamas
Research

Research Output 1990 2018

  • 19177 Citations
  • 113 Article
12 Citations

Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

Amaral, P. P., Leonardi, T., Han, N., Viré, E., Gascoigne, D. K., Arias-Carrasco, R., Büscher, M., Pandolfini, L., Zhang, A., Pluchino, S., Maracaja-Coutinho, V., Nakaya, H. I., Hemberg, M., Shiekhattar, R., Enright, A. J. & Kouzarides, T., Mar 15 2018, In : Genome Biology. 19, 1, 32.

Research output: Contribution to journalArticle

Long Noncoding RNA
anchor
RNA
genomics
chromatin

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms

Chan, H. L., Beckedorff, F., Zhang, Y., Garcia-Huidobro, J., Jiang, H., Colaprico, A., Bilbao, D., Figueroa, M. E., LaCava, J., Shiekhattar, R. & Morey, L., Dec 1 2018, In : Nature communications. 9, 1, 3377.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 1
Gene expression
Genes
Cells
Transcription
3 Citations

Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs

Yue, J., Lai, F., Beckedorff, F., Zhang, A., Pastori, C. & Shiekhattar, R., Sep 1 2017, In : Genes and Development. 31, 17, p. 1809-1820 12 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Immediate-Early Genes
Mutation
Neoplasms
Mediator Complex
9 Citations

Loss of p300 accelerates MDS-associated leukemogenesis

Cheng, G., Liu, F., Asai, T., Lai, F., Man, N., Xu, H., Chen, S., Greenblatt, S., Hamard, P. J., Ando, K., Chen, X., Wang, L., Martinez, C., Tadi, M., Wang, L., Xu, M., Yang, F-C., Shiekhattar, R. & Nimer, S. D., Jan 6 2017, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

CREB-Binding Protein
Myelodysplastic Syndromes
Hematopoietic Stem Cells
Histone Code
Neoplasms
9 Citations

PAF1 regulation of promoter-proximal pause release via enhancer activation

Chen, F. X., Xie, P., Collings, C. K., Cao, K., Aoi, Y., Marshall, S. A., Rendleman, E. J., Ugarenko, M., Ozark, P. A., Zhang, A., Shiekhattar, R., Smith, E. R., Zhang, M. Q. & Shilatifard, A., Sep 22 2017, In : Science. 357, 6357, p. 1294-1298 5 p.

Research output: Contribution to journalArticle

Gene Expression
RNA Polymerase II
Genes