Peter Buchwald

Associate Professor

  • 2790 Citations
19972020

Research output per year

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Research Output

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2020

A Collagen Based Cryogel Bioscaffold that Generates Oxygen for Islet Transplantation

Razavi, M., Primavera, R., Kevadiya, B. D., Wang, J., Buchwald, P. & Thakor, A. S., Apr 1 2020, In : Advanced Functional Materials. 30, 15, 1902463.

Research output: Contribution to journalArticle

Longitudinal proteomics analysis in the immediate microenvironment of islet allografts during progression of rejection

Alcazar, O., Hernandez, L. F., Nakayasu, E. S., Piehowski, P. D., Ansong, C., Abdulreda, M. H. & Buchwald, P., Jul 15 2020, In : Journal of Proteomics. 223, 103826.

Research output: Contribution to journalArticle

2019

A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells

Qadir, M. M. F., Álvarez-Cubela, S., Belle, K., Sapir, T., Messaggio, F., Johnson, K. B., Umland, O., Hardin, D., Klein, D., Pérez-Álvarez, I., Sadiq, F., Alcázar, O., Inverardi, L. A., Ricordi, C., Buchwald, P., Fraker, C. A., Pastori, R. L. & Domínguez-Bendala, J., Mar 5 2019, In : Stem Cell Reports. 12, 3, p. 611-623 13 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
Open Access
2 Scopus citations
Open Access
3 Scopus citations

Feasibility of localized metabolomics in the study of pancreatic islets and diabetes

Alcazar, O., Hernandez, L. F., Tschiggfrie, A., Muehlbauer, M. J., Bain, J. R., Buchwald, P. & Abdulreda, M. H., Oct 2019, In : Metabolites. 9, 10, 207.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice

Abdulreda, M. H., Molano, R. D., Faleo, G., Lopez-Cabezas, M., Shishido, A., Ulissi, U., Fotino, C., Hernandez, L. F., Tschiggfrie, A., Aldrich, V. R., Tamayo-Garcia, A., Bayer, A. S., Ricordi, C., Caicedo, A., Buchwald, P., Pileggi, A. & Berggren, P. O., Jul 1 2019, In : Diabetologia. 62, 7, p. 1237-1250 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Design, synthesis, and evaluation of novel immunomodulatory small molecules targeting the CD40–CD154 costimulatory protein-protein interaction

Bojadzic, D., Chen, J., Alcazar, O. & Buchwald, P., 2018, In : Molecules. 23, 5, 1153.

Research output: Contribution to journalArticle

3 Scopus citations
2017
7 Scopus citations

Comprehensive metabolomics study to assess longitudinal biochemical changes and potential early biomarkers in nonobese diabetic mice that progress to diabetes

Buchwald, P., Tamayo-Garcia, A., Ramamoorthy, S., Garcia-Contreras, M., Mendez, A. J. & Ricordi, C., Oct 6 2017, In : Journal of Proteome Research. 16, 10, p. 3873-3890 18 p.

Research output: Contribution to journalArticle

5 Scopus citations

Glucose-stimulated insulin release: Parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets

Buchwald, P., Tamayo-Garcia, A., Manzoli, V., Tomei, A. A. & Stabler, C., 2017, (Accepted/In press) In : Biotechnology and Bioengineering.

Research output: Contribution to journalArticle

21 Scopus citations
6 Scopus citations

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

Garcia-Contreras, M., Tamayo-Garcia, A., Pappan, K. L., Michelotti, G. A., Stabler, C., Ricordi, C. & Buchwald, P., Jun 2 2017, In : Journal of Proteome Research. 16, 6, p. 2294-2306 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Resealable, optically accessible, PDMS-free fluidic platform for ex vivo interrogation of pancreatic islets

Lenguito, G., Chaimov, D., Weitz, J. R., Rodriguez-Diaz, R., Rawal, S. A. K., Tamayo-Garcia, A., Caicedo, A., Stabler, C., Buchwald, P. & Agarwal, A., 2017, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 17, 5, p. 772-781 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction

Chen, J., Song, Y., Bojadzic, D., Tamayo-Garcia, A., Landin, A. M., Blomberg, B. B. & Buchwald, P., Nov 9 2017, In : Journal of Medicinal Chemistry. 60, 21, p. 8906-8922 17 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Cell length growth patterns in fission yeast reveal a novel size control mechanism operating in late G2 phase

Horváth, A., Rácz-Mónus, A., Buchwald, P. & Sveiczer, Á., Sep 1 2016, In : Biology of the Cell. 108, 9, p. 259-277 19 p.

Research output: Contribution to journalArticle

5 Scopus citations

Dose-escalation study of octanoic acid in patients with essential tremor

Voller, B., Lines, E., McCrossin, G., Tinaz, S., Lungu, C., Grimes, G., Starling, J., Potti, G., Buchwald, P., Haubenberger, D. & Hallett, M., Apr 1 2016, In : Journal of Clinical Investigation. 126, 4, p. 1451-1457 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Fully automated islet cell counter (ICC) for the assessment of islet mass, purity, and size distribution by digital image analysis

Buchwald, P., Bernal, A., Echeverri, F., Tamayo-Garcia, A., Linetsky, E. & Ricordi, C., 2016, In : Cell Transplantation. 25, 10, p. 1747-1761 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer

Thakkar, A., Wang, B., Picon-Ruiz, M., Buchwald, P. & Ince, T. A., May 1 2016, In : Breast cancer research and treatment. 157, 1, p. 77-90 14 p.

Research output: Contribution to journalArticle

27 Scopus citations
2015

Biphasic decline of β-cell function with age in euglycemic nonobese diabetic mice parallels diabetes onset

Cechin, S. R., Lopez-Ocejo, O., Karpinsky-Semper, D. & Buchwald, P., Aug 1 2015, In : IUBMB Life. 67, 8, p. 634-644 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

Ince, T. A., Sousa, A. D., Jones, M. A., Harrell, J. C., Agoston, E. S., Krohn, M., Selfors, L. M., Liu, W., Chen, K., Yong, M., Buchwald, P., Wang, B., Hale, K. S., Cohick, E., Sergent, P., Witt, A., Kozhekbaeva, Z., Gao, S., Agoston, A. T., Merritt, M. A. & 5 others, Foster, R., Rueda, B. R., Crum, C. P., Brugge, J. S. & Mills, G. B., Jun 17 2015, In : Nature communications. 6, 7419.

Research output: Contribution to journalArticle

79 Scopus citations

Controlled Release of Dexamethasone from Organosilicone Constructs for Local Modulation of Inflammation in Islet Transplantation

Weaver, J. D., Song, Y., Yang, E. Y., Ricordi, C., Pileggi, A., Buchwald, P. & Stabler, C., Aug 1 2015, In : Tissue Engineering - Part A. 21, 15-16, p. 2250-2261 12 p.

Research output: Contribution to journalArticle

12 Scopus citations
16 Scopus citations

Phosphorylation-dependent inhibition of Cdc42 GEF Gef1 by 14-3-3 protein Rad24 spatially regulates Cdc42 GTPase activity and oscillatory dynamics during cell morphogenesis

Das, M., Nuñeza, I., Rodriguez, M., Wiley, D. J., Rodriguez, J., Sarkeshik, A., Yates, J. R., Buchwald, P. & Verde, F., Oct 1 2015, In : Molecular biology of the cell. 26, 19, p. 3520-3534 15 p.

Research output: Contribution to journalArticle

22 Scopus citations

TNF superfamily protein-protein interactions: Feasibility of small-molecule modulation

Song, Y. & Buchwald, P., Jan 1 2015, In : Current Drug Targets. 16, 4, p. 393-408 16 p.

Research output: Contribution to journalArticle

14 Scopus citations
2014
4 Scopus citations

Bilinear model for the size-dependency of the CYP3A4 inhibitory activity of structurally diverse compounds

Buchwald, P. & Yamashita, F., Jan 1 2014, In : Molecular Informatics. 33, 1, p. 8-14 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of representative glucocorticoids on TNFα- and CD40L-induced NF-κB activation in sensor cells

Cechin, S. R. & Buchwald, P., Jul 2014, In : Steroids. 85, p. 36-43 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Small-molecule modulators of the OX40OX40 ligand co-stimulatory proteinprotein interaction

Song, Y., Margolles-Clark, E., Bayer, A. & Buchwald, P., Nov 2014, In : British Journal of Pharmacology. 171, 21, p. 4955-4969 15 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Cell length growth in fission yeast: An analysis of its bilinear character and the nature of its rate change transition

Horváth, A., Rácz-Mónus, A., Buchwald, P. & Sveiczer, Á., Nov 1 2013, In : FEMS Yeast Research. 13, 7, p. 635-649 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Octanoic acid in alcohol-responsive essential tremor: A randomized controlled study

Haubenberger, D., McCrossin, G., Lungu, C., Considine, E., Toro, C., Nahab, F. B., Auh, S., Buchwald, P., Grimes, G. J., Starling, J., Potti, G., Scheider, L., Kalowitz, D., Bowen, D., Carnie, A. & Hallett, M., Mar 5 2013, In : Neurology. 80, 10, p. 933-940 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

The promiscuous protein binding ability of erythrosine B studied by metachromasy (metachromasia)

Ganesan, L. & Buchwald, P., Apr 1 2013, In : Journal of Molecular Recognition. 26, 4, p. 181-189 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Exploratory computational assessment of possible binding modes for small molecule inhibitors of the CD40-CD154 co-stimulatory interaction

Ganesan, L., Vidović, D., Schürer, S. C. & Buchwald, P., Jun 21 2012, In : Pharmazie. 67, 5, p. 374-379 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Feasibility of localized immunosuppression: 3. Preliminary evaluation of organosilicone constructs designed for sustained drug release in a cell transplant environment using dexamethasone

Song, Y., Margolles-Clark, E., Fraker, C. A., Weaver, J. D., Ricordi, C., Pileggi, A., Stabler, C. & Buchwald, P., Jun 21 2012, In : Pharmazie. 67, 5, p. 394-399 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Oscillatory dynamics of Cdc42 GTPase in the control of polarized growth

Das, M., Drake, T., Wiley, D. J., Buchwald, P., Vavylonis, D. & Verde, F., Jul 13 2012, In : Science. 337, 6091, p. 239-243 5 p.

Research output: Contribution to journalArticle

87 Scopus citations
2011
60 Scopus citations

An Open-Label, Single-Dose, Crossover Study of the Pharmacokinetics and Metabolism of Two Oral Formulations of 1-Octanol in Patients with Essential Tremor

Nahab, F. B., Wittevrongel, L., Ippolito, D., Toro, C., Grimes, G. J., Starling, J., Potti, G., Haubenberger, D., Bowen, D., Buchwald, P., Dong, C., Kalowitz, D. & Hallett, M., Oct 2011, In : Neurotherapeutics. 8, 4, p. 753-762 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Quantification of the islet product: Presentation of a standardized current good manufacturing practices compliant system with minimal variability

Friberg, A. S., Brandhorst, H., Buchwald, P., Goto, M., Ricordi, C., Brandhorst, D. & Korsgren, O., Mar 27 2011, In : Transplantation. 91, 6, p. 677-683 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

The food colorant erythrosine is a promiscuous protein-protein interaction inhibitor

Ganesan, L., Margolles-Clark, E., Song, Y. & Buchwald, P., Mar 15 2011, In : Biochemical Pharmacology. 81, 6, p. 810-818 9 p.

Research output: Contribution to journalArticle

39 Scopus citations
2010

Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients

Han, D., Berman, D. M., Willman, M., Buchwald, P., Rothen, D., Kenyon, N. M. & Kenyon, N. S., Dec 1 2010, In : Cell Transplantation. 19, 12, p. 1547-1561 15 p.

Research output: Contribution to journalArticle

10 Scopus citations
14 Scopus citations

Feasibility of localized immunosuppression: 2. PLA microspheres for the sustained local delivery of a soft immunosuppressant

Pinto, E., Zhang, B., Song, S., Bodor, N., Buchwald, P. & Hochhaus, G., Jun 1 2010, In : Pharmazie. 65, 6, p. 429-435 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Feasibility of localized immunosuppression: 1. Exploratory studies with glucocorticoids in a biohybrid device designed for cell transplantation

Buchwald, P., Bocca, N., Marzorati, S., Hochhaus, G., Bodor, N., Stabler, C., Kenyon, N. S., Inverardi, L., Molano, R. D., Ricordi, C. & Pileggi, A., Jun 1 2010, In : Pharmazie. 65, 6, p. 421-428 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gβ5-RGS7

Sandiford, S. L., Wang, Q., Levay, K., Buchwald, P. & Slepak, V. Z., Jun 22 2010, In : Biochemistry. 49, 24, p. 4998-5006 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
10 Scopus citations

Pharmacokinetics and Δ1-cortienic acid excretion after intravenous administration of prednisolone and loteprednol etabonate in rats

Wu, W. M., Tang, Y., Buchwald, P. & Bodor, N., Jun 1 2010, In : Pharmazie. 65, 6, p. 412-416 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
2009
77 Scopus citations

Quantitative assessment of islet cell products: Estimating the accuracy of the existing protocol and accounting for islet size distribution

Buchwald, P., Wang, X., Khan, A., Bernal, A., Fraker, C., Inverardi, L. & Ricordi, C., Dec 1 2009, In : Cell Transplantation. 18, 10-11, p. 1223-1235 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

Small-molecule costimulatory blockade: Organic dye inhibitors of the CD40-CD154 interaction

Margolles-Clark, E., Umland, O., Kenyon, N. S., Ricordi, C. & Buchwald, P., Nov 1 2009, In : Journal of Molecular Medicine. 87, 11, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Suramin inhibits the CD40-CD154 costimulatory interaction: A possible mechanism for immunosuppressive effects

Margolles-Clark, E., Jacques-Silva, M. C., Ganesan, L., Umland, O., Kenyon, N. S., Ricordi, C., Berggren, P-O. Y. & Buchwald, P., Apr 1 2009, In : Biochemical Pharmacology. 77, 7, p. 1236-1245 10 p.

Research output: Contribution to journalArticle

24 Scopus citations