Pedro J Salas, M.D., Ph.D.

Professor

  • 1763 Citations
1975 …2022
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Epithelial Cells Medicine & Life Sciences
Intermediate Filaments Medicine & Life Sciences
Madin Darby Canine Kidney Cells Medicine & Life Sciences
Cell Membrane Medicine & Life Sciences
Keratins Medicine & Life Sciences
Membrane Proteins Medicine & Life Sciences
Epithelium Medicine & Life Sciences
Membranes Medicine & Life Sciences

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Projects 1995 2022

NF-kappa B
Inflammation
Tight Junctions
Epithelial Cells
Anti-Inflammatory Agents

Microvillus Inclusion Disease: polarized traffic and signaling, a lead to therapy

Salas, P. J. & Ameen, N. A.

National Institutes of Health

9/22/158/31/16

Project: Research projectHigh Priority, Short Term Project Award

Diarrhea
Microvilli
Myosins
Therapeutics
Enterocytes

Acquisition of a Transmission Electron Microscope to Reactivate Facility

Salas, P. J.

National Institutes of Health

6/1/125/31/13

Project: Research projectBiomedical Research Support Shared Instrumentation Grants

electron
electron microscopy
medicine
train
instrumentation
Tight Junctions
Intermediate Filaments
Intestinal Mucosa
Keratins
Inflammatory Bowel Diseases
Cytoskeleton
Intestinal Mucosa
Epithelial Cells
Inflammation
Colitis

Research Output 1975 2016

  • 1763 Citations
  • 59 Article
  • 1 Comment/debate
3 Citations

Conditional knockout of polarity complex (atypical) PKCi reveals an anti-inflammatory function mediated by NF-κB

Forteza, R., Figueroa, Y., Mashukova, A., Dulam, V. & Salas, P. J., Jul 15 2016, In : Molecular Biology of the Cell. 27, 14, p. 2186-2197 12 p.

Research output: Contribution to journalArticle

Anti-Inflammatory Agents
Epithelium
Claudin-4
Caenorhabditis elegans
Intestinal Mucosa
2 Citations

Functional Analysis of Keratin-Associated Proteins in Intestinal Epithelia Heat-Shock Protein Chaperoning and Kinase Rescue

Mashukova, A., Forteza, R. & Salas, P. J., 2016, In : Methods in Enzymology. 569, p. 139-154 16 p.

Research output: Contribution to journalArticle

Functional analysis
Intermediate Filaments
Intestinal Mucosa
Keratins
Heat-Shock Proteins
10 Citations

Multiple roles for keratin intermediate filaments in the regulation of epithelial barrier function and apico-basal polarity

Salas, P. J., Forteza, R. & Mashukova, A., May 11 2016, (Accepted/In press) In : Tissue Barriers.

Research output: Contribution to journalArticle

Intermediate Filaments
Keratins
Genes
Vertebrates
Type I Keratin
16 Citations

Human intestinal epithelial cells express interleukin-10 through Toll-like receptor 4-mediated epithelial-macrophage crosstalk

Hyun, J., Romero, L., Riveron, R., Flores, C., Kanagavelu, S., Chung, K. D., Alonso, A., Sotolongo, J., Ruiz, J., Manukyan, A., Chun, S., Singh, G., Salas, P. J., Targan, S. R. & Fukata, M., Jan 1 2014, In : Journal of Innate Immunity. 7, 1, p. 87-101 15 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Interleukin-10
Epithelial Cells
Macrophages
Cyclooxygenase 2
16 Citations
Myosins
Phosphatidylinositols
Protein Kinases
Enterocytes
Phosphotransferases