Norma S Kenyon

Professor

  • 4888 Citations
1987 …2019

Research output per year

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Research Output

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Article
2002

Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors

Curran, M. A., Ochoa, M. S., Molano, R. D., Pileggi, A., Inverardi, L., Kenyon, N. S., Nolan, G. P., Ricordi, C. & Fenjves, E. S., Aug 2002, In : Transplantation. 74, 3, p. 299-306 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Elevation of cytotoxic lymphocyte gene expression is predictive of islet allograft rejection in nonhuman primates

Han, D., Xu, X., Pastori, R. L., Ricordi, C. & Kenyon, N. S., Jan 1 2002, In : Diabetes. 51, 3, p. 562-566 5 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations
2003

A novel micro-cell-mediated lympholytic assay for the evaluation of regulatory cells in human alloreactive CTL responses

Mathew, J. M., Blomberg, B., Fuller, L., Burke, G. W., Ciancio, G., Kenyon, N., Ricordi, C., Tzakis, A. G., Esquenazi, V. & Miller, J., Jan 15 2003, In : Journal of Immunological Methods. 272, 1-2, p. 67-80 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Human, nonhuman primate, and rat pancreatic islets express erythropoietin receptors

Fenjves, E. S., Ochoa, M. S., Cabrera, O., Mendez, A. J., Kenyon, N. S., Inverardi, L. & Ricordi, C., Apr 27 2003, In : Transplantation. 75, 8, p. 1356-1360 5 p.

Research output: Contribution to journalArticle

60 Scopus citations
2004
52 Scopus citations

Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets

Klein, D., Ribeiro, M. M., Mendoza, V., Jayaraman, S., Kenyon, N. S., Pileggi, A., Molano, R. D., Inverardi, L., Ricordi, C. & Pastori, R. L., Oct 15 2004, In : Biochemical and biophysical research communications. 323, 2, p. 473-478 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, and FTY720

Wijkstrom, M., Kenyon, N. S., Kirchhof, N., Kenyon, N. M., Mullon, C., Lake, P., Cottens, S., Ricordi, C. & Hering, B. J., Mar 27 2004, In : Transplantation. 77, 6, p. 827-835 9 p.

Research output: Contribution to journalArticle

66 Scopus citations

The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge

Ferrant, J. L., Benjamin, C. D., Cutler, A. H., Kalled, S. L., Hsu, Y. M., Garber, E. A., Hess, D. M., Shapiro, R. I., Kenyon, N. S., Harlan, D. M., Kirk, A. D., Burkly, L. C. & Taylor, F. R., Nov 1 2004, In : International Immunology. 16, 11, p. 1583-1594 12 p.

Research output: Contribution to journalArticle

39 Scopus citations
2005

Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival

Adams, A. B., Shirasugi, N., Jones, T. R., Durham, M. M., Strobert, E. A., Cowan, S., Rees, P., Hendrix, R., Price, K., Kenyon, N. S., Hagerty, D., Townsend, R., Hollenbaugh, D., Pearson, T. C. & Larsen, C. P., Jan 1 2005, In : Journal of Immunology. 174, 1, p. 542-550 9 p.

Research output: Contribution to journalArticle

Open Access
148 Scopus citations

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

Kent, S. C., Chen, Y., Bregoli, L., Clemmings, S. M., Kenyon, N. S., Ricordi, C., Hering, B. J. & Hafler, D. A., May 12 2005, In : Nature. 435, 7039, p. 224-228 5 p.

Research output: Contribution to journalArticle

314 Scopus citations

Immunology: Insulin auto-antigenicity in type 1 diabetes (Reply)

Hafler, D. A., Kent, S. C., Chen, Y., Bregoli, L., Clemmings, S. M., Bernhard, H., Norma Sue, K. & Camillo, R., Nov 24 2005, In : Nature. 438, 7067, p. E5-E6

Research output: Contribution to journalArticle

14 Scopus citations

Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience

Froud, T., Ricordi, C., Baidal, D. A., Hafiz, M. M., Ponte, G., Cure, P., Pileggi, A., Poggioli, R., Ichii, H., Khan, A., Ferreira, J. V., Pugliese, A., Esquenazi, V. V., Kenyon, N. S. & Alejandro, R., Aug 1 2005, In : American Journal of Transplantation. 5, 8, p. 2037-2046 10 p.

Research output: Contribution to journalArticle

274 Scopus citations

Loss of IL-4 secretion from human type 1a diabetic pancreatic draining lymph node NKT cells

Kent, S. C., Chen, Y., Clemmings, S. M., Viglietta, V., Kenyon, N. S., Ricordi, C., Hering, B. & Hafler, D. A., Oct 1 2005, In : Journal of Immunology. 175, 7, p. 4458-4464 7 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations

Omental anatomy of non-human primates

Chaffanjon, P. C. J., Kenyon, N. M., Ricordi, C. & Kenyon, N. S., Nov 1 2005, In : Surgical and Radiologic Anatomy. 27, 4, p. 287-291 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Peripheral blood cytotoxic lymphocyte gene transcript levels differ in patients with long-term type 1 diabetes compared to normal controls

Han, D., Leith, J., Alejandro, R., Bolton, W., Ricordi, C. & Kenyon, N. S., Jan 1 2005, In : Cell Transplantation. 14, 6, p. 403-409 7 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2006

CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets

Barbé-Tuana, F. M., Klein, D., Ichii, H., Berman, D. M., Coffey, L., Kenyon, N. S., Ricordi, C. & Pastori, R. L., Sep 1 2006, In : Diabetes. 55, 9, p. 2437-2445 9 p.

Research output: Contribution to journalArticle

44 Scopus citations
679 Scopus citations
2007

Allosensitization of islet allograft recipients

Cardani, R., Pileggi, A., Ricordi, C., Gomez, C., Baidal, D. A., Ponte, G. G., Mineo, D., Faradji, R. N., Froud, T., Ciancio, G., Esquenazi, V., Burke, G. W., Selvaggi, G., Miller, J., Kenyon, N. S. & Alejandro, R., Dec 1 2007, In : Transplantation. 84, 11, p. 1413-1427 15 p.

Research output: Contribution to journalArticle

40 Scopus citations

Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model

Berman, D. M., Cabrera, O., Kenyon, N. M., Miller, J., Tam, S. H., Khandekar, V. S., Picha, K. M., Soderman, A. R., Jordan, R. E., Bugelski, P. J., Horninger, D., Lark, M., Davis, J. E., Alejandro, R., Berggren, P. O., Zimmerman, M., O'Neil, J. J., Ricordi, C. & Kenyon, N. S., Aug 1 2007, In : Transplantation. 84, 3, p. 308-315 8 p.

Research output: Contribution to journalArticle

55 Scopus citations
3 Scopus citations
2008

Automated, high-throughput assays for evaluation of human pancreatic islet function

Cabrera, O., Jacques-Silva, M. C., Berman, D. M., Fachado, A., Echeverri, F., Poo, R., Khan, A., Kenyon, N. S., Ricordi, C., Berggren, P. O. & Caicedo, A., May 30 2008, In : Cell Transplantation. 16, 10, p. 1039-1048 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Combined islet and hematopoietic stem cell allotransplantation: A clinical pilot trial to induce chimerism and graft tolerance

Mineo, D., Ricordi, C., Xu, X., Pileggi, A., Garcia-Morales, R., Khan, A., Baidal, D. A., Han, D., Monroy, K., Miller, J., Pugliese, A., Froud, T., Inverardi, L., Kenyon, N. S. & Alejandro, R., Jun 1 2008, In : American Journal of Transplantation. 8, 6, p. 1262-1274 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Glutamate Is a Positive Autocrine Signal for Glucagon Release

Cabrera, O., Jacques-Silva, M. C., Speier, S., Yang, S. N., Köhler, M., Fachado, A., Vieira, E., Zierath, J. R., Kibbey, R., Berman, D. M., Kenyon, N. S., Ricordi, C., Caicedo, A. & Berggren, P. O., Jun 4 2008, In : Cell Metabolism. 7, 6, p. 545-554 10 p.

Research output: Contribution to journalArticle

105 Scopus citations

Hepatocyte growth factor enhances engraftment and function of nonhuman primate islets

Fiaschi-Taesch, N. M., Berman-Weinberg, D., Sicari, B. M., Takane, K. K., Garcia-Ocaña, A., Ricordi, C., Kenyon, N. S. & Stewart, A. F., Oct 1 2008, In : Diabetes. 57, 10, p. 2745-2754 10 p.

Research output: Contribution to journalArticle

Hepatocyte growth factor enhances engraftment and function of nonhuman primate islets

Fiaschi-Taesch, N. M., Berman-Weinberg, D., Sicari, B. M., Takane, K. K., Garcia-Ocaña, A., Ricordi, C., Kenyon, N. S. & Stewart, A. F., Jan 1 2008, In : Diabetes. 57, 10, p. 2745-2754 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes

Froud, T., Baidal, D. A., Faradji, R., Cure, P., Mineo, D., Selvaggi, G., Kenyon, N. S., Ricordi, C. & Alejandro, R., Dec 27 2008, In : Transplantation. 86, 12, p. 1695-1701 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
2009

Immune cell populations in nonhuman primate islets

Coffey, L. C. K., Berman, D. M., Willman, M. A. & Kenyon, N. S., Dec 1 2009, In : Cell Transplantation. 18, 10-11, p. 1213-1222 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold

Berman, D. M., O'Neil, J. J., Coffey, L. C. K., Chaffanjon, P. C. J., Kenyon, N. M., Ruiz, P., Pileggi, A., Ricordi, C. & Kenyon, N. S., Jan 1 2009, In : American Journal of Transplantation. 9, 1, p. 91-104 14 p.

Research output: Contribution to journalArticle

85 Scopus citations

Small-molecule costimulatory blockade: Organic dye inhibitors of the CD40-CD154 interaction

Margolles-Clark, E., Umland, O., Kenyon, N. S., Ricordi, C. & Buchwald, P., Nov 1 2009, In : Journal of Molecular Medicine. 87, 11, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Suramin inhibits the CD40-CD154 costimulatory interaction: A possible mechanism for immunosuppressive effects

Margolles-Clark, E., Jacques-Silva, M. C., Ganesan, L., Umland, O., Kenyon, N. S., Ricordi, C., Berggren, P. O. & Buchwald, P., Apr 1 2009, In : Biochemical Pharmacology. 77, 7, p. 1236-1245 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2010

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic β cell

Jacques-Silva, M. C., Correa-Medina, M., Cabrera, O., Rodriguez-Diaz, R., Makeeva, N., Fachado, A., Diez, J., Berman, D. M., Kenyon, N. S., Ricordi, C., Pileggi, A., Molano, R. D., Berggren, P. O. & Caicedo, A., Apr 6 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 14, p. 6465-6470 6 p.

Research output: Contribution to journalArticle

87 Scopus citations

Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients

Han, D., Berman, D. M., Willman, M., Buchwald, P., Rothen, D., Kenyon, N. M. & Kenyon, N. S., Dec 1 2010, In : Cell Transplantation. 19, 12, p. 1547-1561 15 p.

Research output: Contribution to journalArticle

10 Scopus citations
14 Scopus citations

Endotoxin deactivation by transient acidification

Ribeiro, M. M., Xu, X., Klein, D., Kenyon, N. S., Ricordi, C., Felipe, M. S. S. & Pastori, R. L., Nov 22 2010, In : Cell Transplantation. 19, 8, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Feasibility of localized immunosuppression: 1. Exploratory studies with glucocorticoids in a biohybrid device designed for cell transplantation

Buchwald, P., Bocca, N., Marzorati, S., Hochhaus, G., Bodor, N., Stabler, C., Kenyon, N. S., Inverardi, L., Molano, R. D., Ricordi, C. & Pileggi, A., Jun 1 2010, In : Pharmazie. 65, 6, p. 421-428 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Mesenchymal stem cells enhance allogeneic islet engraftment in nonhuman primates

Berman, D. M., Willman, M. A., Han, D., Kleiner, G., Kenyon, N. M., Cabrera, O., Karl, J. A., Wiseman, R. W., O'Connor, D. H., Bartholomew, A. M. & Kenyon, N. S., Oct 1 2010, In : Diabetes. 59, 10, p. 2558-2568 11 p.

Research output: Contribution to journalArticle

126 Scopus citations
10 Scopus citations
2011

Immune profiling by multiple gene expression analysis in patients at-risk and with type 1 diabetes

Han, D., Leyva, C. A., Matheson, D., Mineo, D., Messinger, S., Blomberg, B. B., Hernandez, A., Meneghini, L. F., Allende, G., Skyler, J. S., Alejandro, R., Pugliese, A. & Kenyon, N. S., Jun 1 2011, In : Clinical Immunology. 139, 3, p. 290-301 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Mesenchymal stem cell labeling and in vitro MR characterization at 1.5 T of new SPIO contrast agent: Molday ION Rhodamine-B™

Addicott, B., Willman, M., Rodriguez, J., Padgett, K., Han, D., Berman, D., Hare, J. M. & Kenyon, N. S., Jan 1 2011, In : Contrast Media and Molecular Imaging. 6, 1, p. 7-18 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

The anterior chamber of the eye as a clinical transplantation site for the treatment of diabetes: A study in a baboon model of diabetes

Perez, V. L., Caicedo, A., Berman, D. M., Arrieta, E., Abdulreda, M. H., Rodriguez-Diaz, R., Pileggi, A., Hernandez, E., Dubovy, S. R., Parel, J. M., Ricordi, C., Kenyon, N. M., Kenyon, N. S. & Berggren, P. O., May 1 2011, In : Diabetologia. 54, 5, p. 1121-1126 6 p.

Research output: Contribution to journalArticle

51 Scopus citations
2012

Innate and adaptive immune gene expression profiles as biomarkers in human type 1 diabetes

Han, D., Cai, X., Wen, J., Matheson, D., Skyler, J. S., Kenyon, N. S. & Chen, Z., Nov 1 2012, In : Clinical and Experimental Immunology. 170, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Decision-making in diabetes mellitus type 1

Rustad, J. K., Musselman, D. L., Skyler, J. S., Matheson, D., Delamater, A., Kenyon, N. S., Cáceda, R. & Nemeroff, C. B., Sep 5 2013, In : Journal of Neuropsychiatry and Clinical Neurosciences. 25, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Macroporous three-dimensional PDMS scaffolds for Extrahepatic Islet Transplantation

Pedraza, E., Brady, A. C., Fraker, C. A., Molano, R. D., Sukert, S., Berman, D. M., Kenyon, N. S., Pileggi, A., Ricordi, C. & Stabler, C. L., Jul 5 2013, In : Cell Transplantation. 22, 7, p. 1123-1125 3 p.

Research output: Contribution to journalArticle

50 Scopus citations
2016

Bioengineering the endocrine pancreas: Intraomental islet transplantation within a biologic resorbable scaffold

Berman-Weinberg, D., Molano, R., Fotino, C., Ulissi, U., Gimeno, J., Mendez, A. J., Kenyon, N. M., Kenyon, N. S., Andrews, D., Ricordi, C. & Pileggi, A., May 1 2016, In : Diabetes. 65, 5, p. 1350-1361 12 p.

Research output: Contribution to journalArticle

46 Scopus citations
2018

Microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin-diabetic non-human primates

Safley, S. A., Kenyon, N. S., Berman-Weinberg, D., Barber, G. F., Willman, M., Duncanson, S., Iwakoshi, N., Holdcraft, R., Gazda, L., Thompson, P., Badell, I. R., Sambanis, A., Ricordi, C. & Weber, C. J., Jan 1 2018, (Accepted/In press) In : Xenotransplantation.

Research output: Contribution to journalArticle

13 Scopus citations

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

Rodriguez Diaz, R., Molano, R., Weitz, J. R., Abdulreda, M. H., Berman-Weinberg, D., Leibiger, B., Leibiger, I. B., Kenyon, N. S., Ricordi, C., Pileggi, A., Caicedo-Vierkant, D. A. & Berggren, P. O., Mar 6 2018, In : Cell Metabolism. 27, 3, p. 549-558.e4

Research output: Contribution to journalArticle

27 Scopus citations
2019

MRI-Guided, noninvasive delivery of magneto-electric drug nanocarriers to the brain in a nonhuman primate

Kaushik, A., Rodriguez, J., Rothen, D., Bhardwaj, V., Jayant, R. D., Pattany, P., Fuentes, B., Chand, H., Kolishetti, N., El-Hage, N., Khalili, K., Kenyon, N. S. & Nair, M., Jan 1 2019, (Accepted/In press) In : ACS Applied Bio Materials.

Research output: Contribution to journalArticle

Operational immune tolerance towards transplanted allogeneic pancreatic islets in mice and a non-human primate

Abdulreda, M. H., Berman, D. M., Shishido, A., Martin, C., Hossameldin, M., Tschiggfrie, A., Hernandez, L. F., Hernandez, A., Ricordi, C., Parel, J. M., Jankowska-Gan, E., Burlingham, W. J., Arrieta-Quintero, E. A., Perez, V. L., Kenyon, N. S. & Berggren, P. O., May 1 2019, In : Diabetologia. 62, 5, p. 811-821 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Transplantation of PEGylated islets enhances therapeutic efficacy in a diabetic nonhuman primate model

Stabler, C. L., Giraldo, J. A., Berman, D. M., Gattás-Asfura, K. M., Willman, M. A., Rabassa, A., Geary, J., Diaz, W., Kenyon, N. S. & Kenyon, N. S., Jan 1 2019, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle