Norma S Kenyon

Professor

  • 4873 Citations
1987 …2019
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Research Output 1987 2019

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3 Citations (Scopus)

Allogeneic hematopoietic stem cell transplantation in recipients of cellular or solid organ allografts.

Kenyon, N. S., Chatzipetrou, M., Tzakis, A., Miller, J., Alejandro, R. & Ricordi, C., Jan 1 1999, In : Cancer Treatment and Research. 101, p. 109-132 24 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Homologous Transplantation
Organ Transplantation
Immunosuppression
Allografts
40 Citations (Scopus)

Allosensitization of islet allograft recipients

Cardani, R., Pileggi, A., Ricordi, C., Gomez, C., Baidal, D., Ponte, G. G., Mineo, D., Faradji, R. N., Froud, T., Ciancio, G., Esquenazi, V., Burke, G. W., Selvaggi, G., Miller, J., Kenyon, N. S. & Alejandro, R., Dec 1 2007, In : Transplantation. 84, 11, p. 1413-1427 15 p.

Research output: Contribution to journalArticle

Allografts
Antibodies
Immunosuppression
Transplants
Graft Survival
6 Citations (Scopus)

Alternatives to immunosuppressive drugs in human islet transplantation.

Cotterell, A. A. & Kenyon, N. S., Aug 1 2002, In : Curr Diab Rep. 2, 4, p. 377-382 6 p.

Research output: Contribution to journalArticle

Islets of Langerhans Transplantation
Immunosuppressive Agents
Hypoglycemia
Pharmaceutical Preparations
Poisons
10 Citations (Scopus)

Analysis of post-transplant immune status in recipients of liver/bone marrow allografts

Chatzipetrou, M. A., Mathew, J. M., Kenyon, N. S., Esquenazi, V., Miller, J., Ricordi, C. & Tzakis, A. G., Dec 1 1999, In : Human Immunology. 60, 12, p. 1281-1288 8 p.

Research output: Contribution to journalArticle

Allografts
Bone Marrow
Tissue Donors
Transplants
Liver
1 Citation (Scopus)

An automated method for flow-cytometric analysis of human vertebral body marrow

Knapp, J. C., Kenyon, N. S., Russell, T. R. & Ricordi, C., Jul 7 1997, In : Transplantation Proceedings. 29, 4

Research output: Contribution to journalArticle

CD Antigens
Cell Separation
Automation
Hematopoietic Stem Cells
Human Body
7 Citations (Scopus)

A novel micro-cell-mediated lympholytic assay for the evaluation of regulatory cells in human alloreactive CTL responses

Mathew, J. M., Blomberg, B. B., Fuller, L., Burke, G. W., Ciancio, G., Kenyon, N. S., Ricordi, C., Tzakis, A. G., Esquenazi, V. & Miller, J., Jan 15 2003, In : Journal of Immunological Methods. 272, 1-2, p. 67-80 14 p.

Research output: Contribution to journalArticle

Cell Count
Tissue Donors
Bone Marrow Cells
Cadaver
Immune System
2 Citations (Scopus)

A simple method for depletion of bone fragments from human vertebral body marrow

Kong, S. S., Selvaggi, G., Kenyon, N. S., Bottino, R., Linetsky, E. & Ricordi, C., Dec 1 1995, In : Transplantation Proceedings. 27, 6

Research output: Contribution to journalArticle

Immunologic Graft Enhancement
Colony-Forming Units Assay
Cell Separation
Bone Marrow Transplantation
Centrifugation
52 Citations (Scopus)
Allografts
Lymphocytes
Gene Expression
Insulin
Genes
87 Citations (Scopus)

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic β cell

Jacques-Silva, M. C., Correa-Medina, M., Cabrera, O., Rodriguez Diaz, R., Makeeva, N., Fachado, A., Diez, J., Berman-Weinberg, D., Kenyon, N. S., Ricordi, C., Pileggi, A., Molano, R., Berggren, P. O. & Caicedo-Vierkant, D. A., Apr 6 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 14, p. 6465-6470 6 p.

Research output: Contribution to journalArticle

Purinergic P2X3 Receptors
Adenosine Triphosphate
Insulin
Glucose
Cell Membrane
34 Citations (Scopus)

Automated, high-throughput assays for evaluation of human pancreatic islet function

Cabrera, O., Jacques-Silva, M. C., Berman-Weinberg, D., Fachado, A., Echeverri, F., Poo, R., Khan, A., Kenyon, N. S., Ricordi, C., Berggren, P. O. & Caicedo-Vierkant, D. A., May 30 2008, In : Cell Transplantation. 16, 10, p. 1039-1048 10 p.

Research output: Contribution to journalArticle

Islets of Langerhans
Assays
Throughput
Technology
Biological Phenomena
1 Citation (Scopus)
Immunologic Graft Enhancement
CD34 Antigens
Colony-Forming Units Assay
Cell Separation
Hematopoietic Stem Cells
45 Citations (Scopus)

Bioengineering the endocrine pancreas: Intraomental islet transplantation within a biologic resorbable scaffold

Berman-Weinberg, D., Molano, R., Fotino, C., Ulissi, U., Gimeno, J., Mendez, A. J., Kenyon, N. M., Kenyon, N. S., Andrews, D., Ricordi, C. & Pileggi, A., May 1 2016, In : Diabetes. 65, 5, p. 1350-1361 12 p.

Research output: Contribution to journalArticle

Bioengineering
Islets of Langerhans Transplantation
Islets of Langerhans
Macroglobulins
Phase II Clinical Trials
132 Citations (Scopus)

Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates

Adams, A. B., Shirasugi, N., Durham, M. M., Strobert, E., Andersen, D., Rees, P., Cowan, S., Xu, H., Blinder, Y., Cheung, M., Hollenbaugh, D., Kenyon, N. S., Pearson, T. C. & Larsen, C. P., Jul 24 2002, In : Diabetes. 51, 2, p. 265-270 6 p.

Research output: Contribution to journalArticle

Primates
Immunosuppressive Agents
Sirolimus
Immunosuppression
Allografts
44 Citations (Scopus)

CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets

Barbé-Tuana, F. M., Klein, D., Ichii, H., Berman-Weinberg, D., Coffey, L., Kenyon, N. S., Ricordi, C. & Pastori, R., Sep 1 2006, In : Diabetes. 55, 9, p. 2437-2445 9 p.

Research output: Contribution to journalArticle

CD40 Ligand
Islets of Langerhans
Macrophage Inflammatory Proteins
Inflammation
Interleukin-8
33 Citations (Scopus)

Cell cycle regulated expression of nucleolar antigen P120 in normal and transformed human fibroblasts

Fonagy, A., Swiderski, C., Wilson, A., Bolton, W., Kenyon, N. S. & Freeman, J. W., Jan 1 1993, In : Journal of Cellular Physiology. 154, 1, p. 16-27 12 p.

Research output: Contribution to journalArticle

Fibroblasts
Cell Cycle
Cells
Antigens
Proteins
21 Citations (Scopus)

Cellular immune responses of human cadaver donor bone marrow cells and their susceptibility to commonly used immunosuppressive drugs in transplantation

Mathew, J. M., Carreno, M., Zucker, K., Fuller, L., Kenyon, N. S., Esquenazi, V., Ricordi, C., Tzakis, A. G. & Miller, J., Apr 15 1998, In : Transplantation. 65, 7, p. 947-955 9 p.

Research output: Contribution to journalArticle

Immunosuppressive Agents
Cadaver
Cellular Immunity
Bone Marrow Cells
Transplantation
1 Citation (Scopus)

Characterization of baboon vertebral body marrow

Kenyon, N. S., Knapp, J. C., Xu, X. M., Selvaggi, G., Fernandez, L., McMannis, J. & Ricordi, C., Jul 7 1997, In : Transplantation Proceedings. 29, 4

Research output: Contribution to journalArticle

CD34 Antigens
Cell Separation
Papio
Differentiation Antigens
Hematopoietic Stem Cells
1 Citation (Scopus)

Characterization of pediatric vertebral bone marrow

Kong, S. S., Knapp, J., Selvaggi, G., Kenyon, N. S. & Ricordi, C., Jul 7 1997, In : Transplantation Proceedings. 29, 4

Research output: Contribution to journalArticle

CD Antigens
CD34 Antigens
Colony-Forming Units Assay
Immunophenotyping
HLA-DR Antigens
10 Citations (Scopus)

Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients

Han, D., Berman-Weinberg, D., Willman, M., Buchwald, P., Rothen, D. E., Kenyon, N. M. & Kenyon, N. S., Dec 1 2010, In : Cell Transplantation. 19, 12, p. 1547-1561 15 p.

Research output: Contribution to journalArticle

Macaca fascicularis
Cytomegalovirus
Lymphocytes
Immunosuppression
Allografts
37 Citations (Scopus)

Combined islet and hematopoietic stem cell allotransplantation: A clinical pilot trial to induce chimerism and graft tolerance

Mineo, D., Ricordi, C., Xu, X., Pileggi, A., Garcia-Morales, R., Khan, A., Baidal, D., Han, D., Monroy, K., Miller, J., Pugliese, A., Froud, T., Inverardi, L. A., Kenyon, N. S. & Alejandro, R., Jun 1 2008, In : American Journal of Transplantation. 8, 6, p. 1262-1274 13 p.

Research output: Contribution to journalArticle

Transplantation Tolerance
Chimerism
Hematopoietic Stem Cells
Immunosuppression
Clinical Trials
55 Citations (Scopus)

Continuing observations on the regulatory effects of donor-specific bone marrow cell infusions and chimerism in kidney transplant recipients

Garcia-Morales, R., Carreno, M., Mathew, J., Cirocco, R., Zucker, K., Ciancio, G., Burke, G. W., Roth, D., Temple, D., Fuller, L., Esquenazi, V., Eskind, L., Kenyon, N. S., Ricordi, C., Tzakis, A. & Miller, J., Apr 15 1998, In : Transplantation. 65, 7, p. 956-965 10 p.

Research output: Contribution to journalArticle

Chimerism
Bone Marrow Cells
Tissue Donors
Kidney
Bone Marrow
124 Citations (Scopus)

Current advances and travails in islet transplantation

Harlan, D. M., Kenyon, N. S., Korsgren, O. & Roep, B. O., Oct 1 2009, In : Diabetes. 58, 10, p. 2175-2184 10 p.

Research output: Contribution to journalArticle

Immunologic Monitoring
Islets of Langerhans Transplantation
Homologous Transplantation
Insulin-Secreting Cells
Graft Survival
7 Citations (Scopus)

Current indications and limits of pancreatic islet transplantation in diabetic nephropathy

Masetti, M., Inverardi, L. A., Ranuncoli, A., Iaria, G., Lupo, F., Vizzardelli, C., Kenyon, N. S., Alejandro, R. & Ricordi, C., Sep 1 1997, In : Journal of Nephrology. 10, 5, p. 245-252 8 p.

Research output: Contribution to journalArticle

Islets of Langerhans Transplantation
Diabetic Nephropathies
Insulin
Transplants
Tissue Donors
10 Citations (Scopus)

Decision-making in diabetes mellitus type 1

Rustad, J. K., Musselman, D., Skyler, J. S., Matheson, D., Delamater, A. M., Kenyon, N. S., Cáceda, R. & Nemeroff, C., Sep 5 2013, In : Journal of Neuropsychiatry and Clinical Neurosciences. 25, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Decision Making
Depression
Visual Perception
Aptitude
67 Citations (Scopus)

Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets

Klein, D., Ribeiro, M. M., Mendoza, V., Jayaraman, S., Kenyon, N. S., Pileggi, A., Molano, R., Inverardi, L. A., Ricordi, C. & Pastori, R., Oct 15 2004, In : Biochemical and Biophysical Research Communications. 323, 2, p. 473-478 6 p.

Research output: Contribution to journalArticle

Apoptosis
bcl-X Protein
Cell-Penetrating Peptides
Islets of Langerhans Transplantation
Insulinoma
1 Citation (Scopus)

Depletion of infiltrating leukocytes and identification of normal fibroblasts prior to the proliferative assessment of rare event tumor cells

Schmittling, R., Siiman, O., Kenyon, N. S. & Bolton, W., Jun 16 1993, In : Annals of the New York Academy of Sciences. 677, p. 447-449 3 p.

Research output: Contribution to journalArticle

Magnetics
Lymphocyte Depletion
CD45 Antigens
Cultured Tumor Cells
Tumor-Infiltrating Lymphocytes
148 Citations (Scopus)

Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival

Adams, A. B., Shirasugi, N., Jones, T. R., Durham, M. M., Strobert, E. A., Cowan, S., Rees, P., Hendrix, R., Price, K., Kenyon, N. S., Hagerty, D., Townsend, R., Hollenbaugh, D., Pearson, T. C. & Larsen, C. P., Jan 1 2005, In : Journal of Immunology. 174, 1, p. 542-550 9 p.

Research output: Contribution to journalArticle

Allografts
Monoclonal Antibodies
Islets of Langerhans Transplantation
Cell- and Tissue-Based Therapy
Primates
11 Citations (Scopus)

Donor peripheral blood stem cell infusions in recipients of living- related liver allografts

Tsaroucha, A. K., Ricordi, C., Noto, T. A., Kenyon, N. S., Garcia-Morales, R., Nery, J. R., Miller, J. & Tzakis, A. G., Jul 27 1997, In : Transplantation. 64, 2, p. 362-364 3 p.

Research output: Contribution to journalArticle

Allografts
Tissue Donors
Liver
Leukapheresis
Transplants
7 Citations (Scopus)

Downregulation of antidonor cytotoxic lymphocyte responses in recipients of donor-specific transfusions

Hadley, G. A., Kenyon, N. S., Anderson, C. B. & Mohanakumar, T., Dec 1 1990, In : Transplantation. 50, 6, p. 1064-1066 3 p.

Research output: Contribution to journalArticle

Transplantation Immunology
Cytotoxic T-Lymphocytes
Blood Transfusion
Kidney Transplantation
Down-Regulation
14 Citations (Scopus)
Derivatives
Transplants
CD40 Ligand
Acids
T-cells
Immunologic Graft Enhancement
CD34 Antigens
Colony-Forming Units Assay
Islets of Langerhans Transplantation
Cell Separation
32 Citations (Scopus)

Effect of living-related donor bone marrow infusion on chimerism and in vitro immunoregulatory activity in kidney transplant recipients

Ciancio, G., Burke, G. W., Garcia-Morales, R., Suzart, K., Rosen, A., Ricordi, C., Kenyon, N. S., Mathew, J. M., Tzakis, A. G., Esquenazi, V. & Miller, J., Aug 27 2002, In : Transplantation. 74, 4, p. 488-496 9 p.

Research output: Contribution to journalArticle

Chimerism
Living Donors
Bone Marrow
Tissue Donors
Bone Marrow Cells
1 Citation (Scopus)

Effect of preservation conditions on human vertebral body marrow

Kong, S. S., Kenyon, N. S., Brendel, M., Tzakis, A. G., Miller, J. & Ricordi, C., Dec 1 1995, In : Transplantation Proceedings. 27, 6

Research output: Contribution to journalArticle

Immunologic Graft Enhancement
Colony-Forming Units Assay
Tissue Preservation
Hematopoietic Stem Cells
Bone Marrow Transplantation
49 Citations (Scopus)

Effects of cyclosporin on insulin and C-peptide secretion in healthy beagles

Alejandro, R., Feldman, E. C., Bloom, A. D. & Kenyon, N. S., Dec 1 1989, In : Diabetes. 38, 6, p. 698-703 6 p.

Research output: Contribution to journalArticle

C-Peptide
Cyclosporine
Insulin
Glucose Tolerance Test
Glucagon
18 Citations (Scopus)

Effects of ketamine sedation on glucose clearance, insulin secretion and counterregulatory hormone production in baboons (Papio hamadryas)

Lehmann, R., Wagner, J. L., Fernandez, L. A., Bourgoignie, J. J., Ricordi, C., Alejandro, R. & Kenyon, N. S., Dec 1 1997, In : Journal of Medical Primatology. 26, 6, p. 312-321 10 p.

Research output: Contribution to journalArticle

Papio hamadryas
Papio
insulin secretion
Ketamine
sedation
29 Citations (Scopus)

Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors

Curran, M. A., Ochoa, M. S., Molano, R., Pileggi, A., Inverardi, L. A., Kenyon, N. S., Nolan, G. P., Ricordi, C. & Fenjves, E. S., Aug 1 2002, In : Transplantation. 74, 3, p. 299-306 8 p.

Research output: Contribution to journalArticle

Feline Immunodeficiency Virus
Islets of Langerhans
Green Fluorescent Proteins
Murine Leukemia Viruses
HIV
29 Citations (Scopus)

Elevation of cytotoxic lymphocyte gene expression is predictive of islet allograft rejection in nonhuman primates

Han, D., Xu, X., Pastori, R., Ricordi, C. & Kenyon, N. S., Jul 23 2002, In : Diabetes. 51, 3, p. 562-566 5 p.

Research output: Contribution to journalArticle

Primates
Allografts
Lymphocytes
Gene Expression
Macaca mulatta
11 Citations (Scopus)

Endotoxin contamination of reagents used during isolation and purification of human pancreatic islets

Linetsky, E., Inverardi, L. A., Kenyon, N. S., Alejandro, R. & Ricordi, C., May 18 1998, In : Transplantation Proceedings. 30, 2, p. 345-346 2 p.

Research output: Contribution to journalArticle

Drug Contamination
Islets of Langerhans Transplantation
Macrophage Activation
Cell Separation
Homologous Transplantation
6 Citations (Scopus)

Endotoxin deactivation by transient acidification

Ribeiro, M. M., Xu, X., Klein, D., Kenyon, N. S., Ricordi, C., Felipe, M. S. S. & Pastori, R., Nov 22 2010, In : Cell Transplantation. 19, 8, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

Acidification
Recombinant proteins
Endotoxins
Proteins
Recombinant Proteins
3 Citations (Scopus)

Enhanced assessment of DNA/Proliferative index by depletion of tumor infiltrating leukocytes prior to monoclonal antibody gated analysis of tumor cell DNA

Kenyon, N. S., Schmittling, R. J., Siiman, O., Burshteyn, A. & Bolton, W. E., Jun 24 1994, In : Cytometry. 16, 2, p. 175-183 9 p.

Research output: Contribution to journalArticle

Leukocytes
Monoclonal Antibodies
DNA
Neoplasms
Breast Neoplasms
5 Citations (Scopus)

Enhanced in vitro bone marrow cell migration and T-lymphocyte responses in aged mice given subcutaneous thymic epithelial cell grafts

Haar, J. L., Taubenberger, J. K., Doane, L. & Kenyon, N. S., Jan 1 1989, In : Mechanisms of Ageing and Development. 47, 3, p. 207-219 13 p.

Research output: Contribution to journalArticle

T-cells
Grafts
Bone Marrow Cells
Cell Movement
Bone
1 Citation (Scopus)

Enrichment of hematopoietic stem cells from human vertebral body marrow

Kenyon, N. S., Russell, T. R., Xu, X. M., Knapp, J. & Ricordi, C., Jul 7 1997, In : Transplantation Proceedings. 29, 4

Research output: Contribution to journalArticle

CD Antigens
CD34 Antigens
Colony-Forming Units Assay
Growth Substances
Cell Separation
4 Citations (Scopus)
Homologous Transplantation
Cytotoxic T-Lymphocytes
HLA-DR Antigens
Kidney Transplantation
Allografts
3 Citations (Scopus)
Papio hamadryas
Chimerism
Papio
Bone Marrow Transplantation
15 Citations (Scopus)

Evaluation of islet isolation by a new automated method (Coulter Multisizer IIe) and manual counting

Lehmann, R., Fernandez, L. A., Bottino, R., Szabo, S., Ricordi, C., Alejandro, R. & Kenyon, N. S., Jan 1 1998, In : Transplantation Proceedings. 30, 2, p. 373-374 2 p.

Research output: Contribution to journalArticle

314 Citations (Scopus)

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

Kent, S. C., Chen, Y., Bregoli, L., Clemmings, S. M., Kenyon, N. S., Ricordi, C., Hering, B. J. & Hafler, D. A., May 12 2005, In : Nature. 435, 7039, p. 224-228 5 p.

Research output: Contribution to journalArticle

Epitopes
Type 1 Diabetes Mellitus
Lymph Nodes
Insulin
T-Lymphocytes
1 Citation (Scopus)

Experience with islet immunoalteration in dogs: In vitro and in vivo studies

Kenyon, N. S., Alejandro, R. & Mintz, D. H., Dec 1 1990, In : Hormone and Metabolic Research. 25, SUPPL., p. 119-122 4 p.

Research output: Contribution to journalArticle

Allografts
Dogs
Cyclosporine
Transplantation
Ultraviolet Rays
33 Citations (Scopus)

Expression of proliferation-associated antigens (PCNA, P120, P145) during the reentry of G0 cells into the cell cycle

Bolton, W. E., Freeman, J. W., Mikulka, W. R., Healy, C. G., Schmittling, R. J. & Kenyon, N. S., Sep 8 1994, In : Cytometry. 17, 1, p. 66-74 9 p.

Research output: Contribution to journalArticle

Cell Cycle
Proliferating Cell Nuclear Antigen
Antigens
CHO Cells
DNA
67 Citations (Scopus)

Expression of proliferation associated antigens in the cell cycle of synchronized mammalian cells

Bolton, W. E., Mikulka, W. R., Healy, C. G., Schmittling, R. J. & Kenyon, N. S., Jan 1 1992, In : Cytometry. 13, 2, p. 117-126 10 p.

Research output: Contribution to journalArticle

Cell Cycle
Antigens
Proliferating Cell Nuclear Antigen
DNA
Cell Cycle Resting Phase
15 Citations (Scopus)

Feasibility of localized immunosuppression: 1. Exploratory studies with glucocorticoids in a biohybrid device designed for cell transplantation

Buchwald, P., Bocca, N., Marzorati, S., Hochhaus, G., Bodor, N., Stabler, C., Kenyon, N. S., Inverardi, L. A., Molano, R., Ricordi, C. & Pileggi, A., Jun 1 2010, In : Pharmazie. 65, 6, p. 421-428 8 p.

Research output: Contribution to journalArticle

Cell Transplantation
Immunosuppression
Glucocorticoids
Equipment and Supplies
dexamethasone 21-phosphate