Norma S Kenyon

Professor

  • 4989 Citations
1987 …2020

Research output per year

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Research Output

2020

Transplantation of PEGylated islets enhances therapeutic efficacy in a diabetic nonhuman primate model

Stabler, C., Giraldo, J. A., Berman, D. M., Gattás-Asfura, K. M., Willman, M. A., Rabassa, A., Geary, J., Diaz, W., Kenyon, N. M. & Kenyon, N. S., Mar 1 2020, In : American Journal of Transplantation. 20, 3, p. 689-700 12 p.

Research output: Contribution to journalArticle

2019

MRI-Guided, noninvasive delivery of magneto-electric drug nanocarriers to the brain in a nonhuman primate

Kaushik, A., Rodriguez, J., Rothen, D., Bhardwaj, V., Jayant, R. D., Pattany, P., Fuentes, B., Chand, H., Kolishetti, N., El-Hage, N., Khalili, K., Kenyon, N. S. & Nair, M., Jan 1 2019, (Accepted/In press) In : ACS Applied Bio Materials.

Research output: Contribution to journalArticle

Operational immune tolerance towards transplanted allogeneic pancreatic islets in mice and a non-human primate

Abdulreda, M. H., Berman, D. M., Shishido, A., Martin, C., Hossameldin, M., Tschiggfrie, A., Hernandez, L. F., Hernandez, A., Ricordi, C., Parel, J. M., Jankowska-Gan, E., Burlingham, W. J., Arrieta-Quintero, E. A., Perez Quinones, V. L., Kenyon, N. S. & Berggren, P-O. Y., May 1 2019, In : Diabetologia. 62, 5, p. 811-821 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

We Could Use More Tolerance: Role of Intestinal-Allograft-Derived Human Stem Cells

Kenyon, N. S., Feb 7 2019, In : Cell Stem Cell. 24, 2, p. 197-198 2 p.

Research output: Contribution to journalShort survey

2018

Microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin-diabetic non-human primates

Safley, S. A., Kenyon, N. S., Berman-Weinberg, D., Barber, G. F., Willman, M., Duncanson, S., Iwakoshi, N., Holdcraft, R., Gazda, L., Thompson, P., Badell, I. R., Sambanis, A., Ricordi, C. & Weber, C. J., Jan 1 2018, (Accepted/In press) In : Xenotransplantation.

Research output: Contribution to journalArticle

17 Scopus citations

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

Rodriguez-Diaz, R., Molano, R., Weitz, J. R., Abdulreda, M. H., Berman, D. M., Leibiger, B., Leibiger, I. B., Kenyon, N. S., Ricordi, C., Pileggi, A., Caicedo, A. & Berggren, P-O. Y., Mar 6 2018, In : Cell Metabolism. 27, 3, p. 549-558.e4

Research output: Contribution to journalArticle

36 Scopus citations

Regenerative Medicine in the State of Florida: Letter Outlining the Florida Organization for Regenerative Medicine

Bruce, C. J., Bu, G., Centanni, J. M., Davis, M. D., Dobson, J., Hare, J. M., Fields, G. B., Jove, R., Kenyon, N., Khan, A., March, K., Matosevic, S., Mahmood, A., Pepine, C. J., Ricordi, C., Shapiro, S. A., Zylberberg, C. & Zylberberg, E., Jul 1 2018, In : Stem Cells Translational Medicine. 7, 7, p. 511-512 2 p.

Research output: Contribution to journalLetter

2017

Automatic glomerulus extraction in whole slide images towards computer aided diagnosis

Zhao, Y., Black, E. F., Marini, L., McHenry, K., Kenyon, N. S., Patil, R., Balla, A. & Bartholomew, A., Mar 3 2017, Proceedings of the 2016 IEEE 12th International Conference on e-Science, e-Science 2016. Institute of Electrical and Electronics Engineers Inc., p. 165-174 10 p. 7870897

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations
2016

Bioengineering the endocrine pancreas: Intraomental islet transplantation within a biologic resorbable scaffold

Berman, D. M., Molano, R., Fotino, C., Ulissi, U., Gimeno, J., Mendez, A. J., Kenyon, N. M., Kenyon, N. S., Andrews, D. M., Ricordi, C. & Pileggi, A., May 1 2016, In : Diabetes. 65, 5, p. 1350-1361 12 p.

Research output: Contribution to journalArticle

53 Scopus citations
2015

Clinical Aspects of Regenerative Medicine: Immune System

Szilagyi, E., Sundivakkam, P., Nunez, T., Premenand, K., Kenyon, N. & Bartholomew, A., Jan 1 2015, Translational Regenerative Medicine. Elsevier Inc., p. 507-526 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Using hidden Markov models to determine changes in subject data over time, studying the immunoregulatory effect of mesenchymal stem cells

Black, E. F., Marini, L., Vaidya, A., Berman, D., Willman, M., Salomon, D., Bartholomew, A., Kenyon, N. & McHenry, K., Dec 2 2014, Proceedings - 2014 IEEE 10th International Conference on eScience, eScience 2014. Institute of Electrical and Electronics Engineers Inc., p. 83-91 9 p. 6972252. (Proceedings - 2014 IEEE 10th International Conference on eScience, eScience 2014; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations
2013

Decision-making in diabetes mellitus type 1

Rustad, J. K., Musselman, D. L., Skyler, J. S., Matheson, D., Delamater, A., Kenyon, N. S., Cáceda, R. & Nemeroff, C. B., Sep 5 2013, In : Journal of Neuropsychiatry and Clinical Neurosciences. 25, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Macroporous three-dimensional PDMS scaffolds for Extrahepatic Islet Transplantation

Pedraza, E., Brady, A. C., Fraker, C. A., Molano, R. D., Sukert, S., Berman, D. M., Kenyon, N. S., Pileggi, A., Ricordi, C. & Stabler, C. L., 2013, In : Cell transplantation. 22, 7, p. 1123-1125 3 p.

Research output: Contribution to journalArticle

56 Scopus citations
2012
6 Scopus citations

Innate and adaptive immune gene expression profiles as biomarkers in human type 1 diabetes

Han, D., Cai, X., Wen, J., Matheson, D., Skyler, J. S., Kenyon, N. S. & Chen, Z., Nov 1 2012, In : Clinical and Experimental Immunology. 170, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2011

Immune profiling by multiple gene expression analysis in patients at-risk and with type 1 diabetes

Han, D., Leyva, C. A., Matheson, D., Mineo, D., Messinger, S., Blomberg, B. B., Hernandez, A., Meneghini, L. F., Allende, G., Skyler, J. S., Alejandro, R., Pugliese, A. & Kenyon, N. S., Jun 1 2011, In : Clinical Immunology. 139, 3, p. 290-301 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Mesenchymal stem cell labeling and in vitro MR characterization at 1.5 T of new SPIO contrast agent: Molday ION Rhodamine-B™

Addicott, B., Willman, M., Rodriguez, J., Padgett, K., Han, D., Berman, D., Hare, J. M. & Kenyon, N. S., Jan 1 2011, In : Contrast Media and Molecular Imaging. 6, 1, p. 7-18 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

The anterior chamber of the eye as a clinical transplantation site for the treatment of diabetes: A study in a baboon model of diabetes

Perez, V. L., Caicedo, A., Berman, D. M., Arrieta, E., Abdulreda, M. H., Rodriguez-Diaz, R., Pileggi, A., Hernandez, E., Dubovy, S. R., Parel, J. M., Ricordi, C., Kenyon, N. M., Kenyon, N. S. & Berggren, P-O. Y., May 1 2011, In : Diabetologia. 54, 5, p. 1121-1126 6 p.

Research output: Contribution to journalArticle

52 Scopus citations
2010

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic β cell

Jacques-Silva, M. C., Correa-Medina, M., Cabrera, O., Rodriguez-Diaz, R., Makeeva, N., Fachado, A., Diez, J., Berman, D. M., Kenyon, N. S., Ricordi, C., Pileggi, A., Molano, R. D., Berggren, P-O. Y. & Caicedo, A., Apr 6 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 14, p. 6465-6470 6 p.

Research output: Contribution to journalArticle

88 Scopus citations

Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients

Han, D., Berman, D. M., Willman, M., Buchwald, P., Rothen, D., Kenyon, N. M. & Kenyon, N. S., Dec 1 2010, In : Cell Transplantation. 19, 12, p. 1547-1561 15 p.

Research output: Contribution to journalArticle

10 Scopus citations
14 Scopus citations

Endotoxin deactivation by transient acidification

Ribeiro, M. M., Xu, X., Klein, D., Kenyon, N. S., Ricordi, C., Felipe, M. S. S. & Pastori, R. L., Nov 22 2010, In : Cell Transplantation. 19, 8, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Feasibility of localized immunosuppression: 1. Exploratory studies with glucocorticoids in a biohybrid device designed for cell transplantation

Buchwald, P., Bocca, N., Marzorati, S., Hochhaus, G., Bodor, N., Stabler, C., Kenyon, N. S., Inverardi, L., Molano, R. D., Ricordi, C. & Pileggi, A., Jun 1 2010, In : Pharmazie. 65, 6, p. 421-428 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Mesenchymal stem cells enhance allogeneic islet engraftment in nonhuman primates

Berman, D. M., Willman, M. A., Han, D., Kleiner, G., Kenyon, N. M., Cabrera, O., Karl, J. A., Wiseman, R. W., O'Connor, D. H., Bartholomew, A. M. & Kenyon, N. S., Oct 1 2010, In : Diabetes. 59, 10, p. 2558-2568 11 p.

Research output: Contribution to journalArticle

130 Scopus citations
10 Scopus citations
2009

Current advances and travails in islet transplantation

Harlan, D. M., Kenyon, N. S., Korsgren, O. & Roep, B. O., Oct 1 2009, In : Diabetes. 58, 10, p. 2175-2184 10 p.

Research output: Contribution to journalReview article

127 Scopus citations

Immune cell populations in nonhuman primate islets

Coffey, L. C. K., Berman, D. M., Willman, M. A. & Kenyon, N. S., Dec 1 2009, In : Cell Transplantation. 18, 10-11, p. 1213-1222 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold

Berman, D. M., O'Neil, J. J., Coffey, L. C. K., Chaffanjon, P. C. J., Kenyon, N. M., Ruiz, P., Pileggi, A., Ricordi, C. & Kenyon, N. S., Jan 1 2009, In : American Journal of Transplantation. 9, 1, p. 91-104 14 p.

Research output: Contribution to journalArticle

88 Scopus citations

Mesenchymal stem cells in the induction of transplantation tolerance.

Bartholomew, A., Polchert, D., Szilagyi, E., Douglas, G. W. & Kenyon, N., May 15 2009, In : Transplantation. 87, 9 Suppl, p. S55-57

Research output: Contribution to journalReview article

19 Scopus citations

Pretransplant immune parameters associate with islet allograft outcome: Implications for transplant strategy?

Kenyon, N. S. & Ricordi, C., Oct 1 2009, In : Diabetes. 58, 10, p. 2187-2188 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Small-molecule costimulatory blockade: Organic dye inhibitors of the CD40-CD154 interaction

Margolles-Clark, E., Umland, O., Kenyon, N. S., Ricordi, C. & Buchwald, P., Nov 1 2009, In : Journal of Molecular Medicine. 87, 11, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Suramin inhibits the CD40-CD154 costimulatory interaction: A possible mechanism for immunosuppressive effects

Margolles-Clark, E., Jacques-Silva, M. C., Ganesan, L., Umland, O., Kenyon, N. S., Ricordi, C., Berggren, P-O. Y. & Buchwald, P., Apr 1 2009, In : Biochemical Pharmacology. 77, 7, p. 1236-1245 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2008

Automated, high-throughput assays for evaluation of human pancreatic islet function

Cabrera, O., Jacques-Silva, M. C., Berman, D. M., Fachado, A., Echeverri, F., Poo, R., Khan, A., Kenyon, N. S., Ricordi, C., Berggren, P-O. Y. & Caicedo, A., May 30 2008, In : Cell Transplantation. 16, 10, p. 1039-1048 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Combined islet and hematopoietic stem cell allotransplantation: A clinical pilot trial to induce chimerism and graft tolerance

Mineo, D., Ricordi, C., Xu, X., Pileggi, A., Garcia-Morales, R., Khan, A., Baidal, D. A., Han, D., Monroy, K., Miller, J., Pugliese, A., Froud, T., Inverardi, L., Kenyon, N. S. & Alejandro, R., Jun 1 2008, In : American Journal of Transplantation. 8, 6, p. 1262-1274 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

Glutamate Is a Positive Autocrine Signal for Glucagon Release

Cabrera, O., Jacques-Silva, M. C., Speier, S., Yang, S. N., Köhler, M., Fachado, A., Vieira, E., Zierath, J. R., Kibbey, R., Berman, D. M., Kenyon, N. S., Ricordi, C., Caicedo, A. & Berggren, P-O. Y., Jun 4 2008, In : Cell Metabolism. 7, 6, p. 545-554 10 p.

Research output: Contribution to journalArticle

110 Scopus citations

Hepatocyte growth factor enhances engraftment and function of nonhuman primate islets

Fiaschi-Taesch, N. M., Berman-Weinberg, D., Sicari, B. M., Takane, K. K., Garcia-Ocaña, A., Ricordi, C., Kenyon, N. S. & Stewart, A. F., Jan 1 2008, In : Diabetes. 57, 10, p. 2745-2754 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Hepatocyte growth factor enhances engraftment and function of nonhuman primate islets

Fiaschi-Taesch, N. M., Berman-Weinberg, D., Sicari, B. M., Takane, K. K., Garcia-Ocaña, A., Ricordi, C., Kenyon, N. S. & Stewart, A. F., Oct 1 2008, In : Diabetes. 57, 10, p. 2745-2754 10 p.

Research output: Contribution to journalArticle

Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes

Froud, T., Baidal, D. A., Faradji, R., Cure, P., Mineo, D., Selvaggi, G., Kenyon, N. S., Ricordi, C. & Alejandro, R., Dec 27 2008, In : Transplantation. 86, 12, p. 1695-1701 7 p.

Research output: Contribution to journalArticle

37 Scopus citations
2007

Allosensitization of islet allograft recipients

Cardani, R., Pileggi, A., Ricordi, C., Gomez, C., Baidal, D. A., Ponte, G. G., Mineo, D., Faradji, R. N., Froud, T., Ciancio, G., Esquenazi, V., Burke, G. W., Selvaggi, G., Miller, J., Kenyon, N. S. & Alejandro, R., Dec 1 2007, In : Transplantation. 84, 11, p. 1413-1427 15 p.

Research output: Contribution to journalArticle

41 Scopus citations

Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model

Berman, D. M., Cabrera, O., Kenyon, N. M., Miller, J., Tam, S. H., Khandekar, V. S., Picha, K. M., Soderman, A. R., Jordan, R. E., Bugelski, P. J., Horninger, D., Lark, M., Davis, J. E., Alejandro, R., Berggren, P-O. Y., Zimmerman, M., O'Neil, J. J., Ricordi, C. & Kenyon, N. S., Aug 1 2007, In : Transplantation. 84, 3, p. 308-315 8 p.

Research output: Contribution to journalArticle

56 Scopus citations
3 Scopus citations

The Miami results on porcine islet-Sertoli cell xenotransplantation [1]

Mendez, A. J., Inverardi, L., Ricordi, C. & Kenyon, N. S., Jan 1 2007, In : Xenotransplantation. 14, 1, 1 p.

Research output: Contribution to journalLetter

4 Scopus citations
2006

CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets

Barbé-Tuana, F. M., Klein, D., Ichii, H., Berman, D. M., Coffey, L., Kenyon, N. S., Ricordi, C. & Pastori, R. L., Sep 1 2006, In : Diabetes. 55, 9, p. 2437-2445 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
697 Scopus citations
2005

Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival

Adams, A. B., Shirasugi, N., Jones, T. R., Durham, M. M., Strobert, E. A., Cowan, S., Rees, P., Hendrix, R., Price, K., Kenyon, N. S., Hagerty, D., Townsend, R., Hollenbaugh, D., Pearson, T. C. & Larsen, C. P., Jan 1 2005, In : Journal of Immunology. 174, 1, p. 542-550 9 p.

Research output: Contribution to journalArticle

Open Access
149 Scopus citations

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

Kent, S. C., Chen, Y., Bregoli, L., Clemmings, S. M., Kenyon, N. S., Ricordi, C., Hering, B. J. & Hafler, D. A., May 12 2005, In : Nature. 435, 7039, p. 224-228 5 p.

Research output: Contribution to journalArticle

323 Scopus citations

Immunology: Insulin auto-antigenicity in type 1 diabetes (Reply)

Hafler, D. A., Kent, S. C., Chen, Y., Bregoli, L., Clemmings, S. M., Bernhard, H., Norma Sue, K. & Camillo, R., Nov 24 2005, In : Nature. 438, 7067, p. E5-E6

Research output: Contribution to journalArticle

14 Scopus citations

Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience

Froud, T., Ricordi, C., Baidal, D. A., Hafiz, M. M., Ponte, G., Cure, P., Pileggi, A., Poggioli, R., Ichii, H., Khan, A., Ferreira, J. V., Pugliese, A., Esquenazi, V. V., Kenyon, N. S. & Alejandro, R., Aug 1 2005, In : American Journal of Transplantation. 5, 8, p. 2037-2046 10 p.

Research output: Contribution to journalArticle

277 Scopus citations

Loss of IL-4 secretion from human type 1a diabetic pancreatic draining lymph node NKT cells

Kent, S. C., Chen, Y., Clemmings, S. M., Viglietta, V., Kenyon, N. S., Ricordi, C., Hering, B. & Hafler, D. A., Oct 1 2005, In : Journal of Immunology. 175, 7, p. 4458-4464 7 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations