Nirupa Chaudhari

Professor

  • 3855 Citations
1979 …2024
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Research Output 1979 2019

  • 3855 Citations
  • 63 Article
  • 4 Conference contribution
  • 1 Review article
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Article
2019
1 Citation (Scopus)

Cell-Based Therapy Restores Olfactory Function in an Inducible Model of Hyposmia

Kurtenbach, S., Goss, G. M., Goncalves, S., Choi, R., Hare, J. M., Chaudhari, N. & Goldstein, B. J., Jun 11 2019, In : Stem Cell Reports. 12, 6, p. 1354-1365 12 p.

Research output: Contribution to journalArticle

Open Access
Cell- and Tissue-Based Therapy
Stem cells
Neurons
Stem Cells
Electrophysiology

Oral thermosensing by murine trigeminal neurons: modulation by capsaicin, menthol and mustard oil

Leijon, S. C. M., Neves, A. F., Breza, J. M., Simon, S. A., Chaudhari, N. & Roper, S. D., Jan 1 2019, In : Journal of Physiology.

Research output: Contribution to journalArticle

Thermosensing
Menthol
Capsaicin
Hot Temperature
Neurons
5 Citations (Scopus)

Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals

Ohla, K., Yoshida, R., Roper, S. D., Di Lorenzo, P. M., Victor, J. D., Boughter, J. D., Fletcher, M., Katz, D. B. & Chaudhari, N., Apr 15 2019, In : Chemical senses. 44, 4, p. 237-247 11 p.

Research output: Contribution to journalArticle

Open Access
Mammals
Taste Buds
Neurons
Afferent Neurons
Rhombencephalon
3 Citations (Scopus)

The Role of the Anion in Salt (NaCl) Detection by Mouse Taste Buds

Roebber, J. K., Roper, S. D. & Chaudhari, N., Aug 7 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 32, p. 6224-6232 9 p.

Research output: Contribution to journalArticle

Taste Buds
Anions
Salts
Amiloride
Choline
4 Citations (Scopus)

Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells

Bray, E. R., Yungher, B. J., Levay, K., Ribeiro, M., Dvoryanchikov, G., Ayupe, A. C., Thakor, K., Marks, V., Randolph, M., Danzi, M. C., Schmidt, T. M., Chaudhari, N., Lemmon, V. P., Hattar, S. & Park, K. K., Aug 21 2019, In : Neuron. 103, 4, p. 642-657.e7

Research output: Contribution to journalArticle

Thrombospondin 1
Retinal Ganglion Cells
Axons
Regeneration
Syndecan-1
2017
6 Citations (Scopus)

Transcriptomes and neurotransmitter profiles of classes of gustatory and somatosensory neurons in the geniculate ganglion

Dvoryanchikov, G., Hernandez, D., Roebber, J. K., Hill, D. L., Roper, S. D. & Chaudhari, N., Dec 1 2017, In : Nature Communications. 8, 1, 760.

Research output: Contribution to journalArticle

Geniculate Ganglion
neurotransmitters
neurons
Transcriptome
Neurons
2016
10 Citations (Scopus)

Contribution of polycomb group proteins to olfactory basal stem cell self-renewal in a novel c-KIT+ culture model and in vivo

Goldstein, B. J., Goss, G. M., Choi, R., Saur, D., Seidler, B., Hare, J. M. & Chaudhari, N., Dec 1 2016, In : Development (Cambridge). 143, 23, p. 4394-4404 11 p.

Research output: Contribution to journalArticle

Polycomb-Group Proteins
Olfactory Mucosa
Stem Cells
Adult Stem Cells
Neurogenesis
12 Citations (Scopus)

Differentiation potential of individual olfactory c-Kit+ progenitors determined via multicolor lineage tracing

Goss, G. M., Chaudhari, N., Hare, J., Nwojo, R., Seidler, B., Saur, D. & Goldstein, B. J., Mar 1 2016, In : Developmental Neurobiology. 76, 3, p. 241-251 11 p.

Research output: Contribution to journalArticle

Neurons
Neural Stem Cells
Stem Cells
Clone Cells
Maintenance
2015
16 Citations (Scopus)

A permeability barrier surrounds taste buds in lingual epithelia

Dando, R., Pereira, E., Kurian, M., Barro, R., Chaudhari, N. & Roper, S. D., Jan 1 2015, In : American Journal of Physiology - Cell Physiology. 308, 1, p. C21-C32

Research output: Contribution to journalArticle

Taste Buds
Tongue
Permeability
Epithelium
Aptitude
24 Citations (Scopus)

Breadth of tuning in taste afferent neurons varies with stimulus strength

Wu, A., Dvoryanchikov, G., Pereira, E., Chaudhari, N. & Roper, S. D., Sep 16 2015, In : Nature Communications. 6, 8171.

Research output: Contribution to journalArticle

taste
Afferent Neurons
neurons
stimuli
Neurons
1 Citation (Scopus)

Cocaine decreases saccharin preference without altering sweet taste sensitivity

Roebber, J. K., Izenwasser, S. E. & Chaudhari, N., Jun 1 2015, In : Pharmacology Biochemistry and Behavior. 133, p. 18-24 7 p.

Research output: Contribution to journalArticle

Saccharin
Cocaine
Reward
Motivation
Rodentia
10 Citations (Scopus)

Oxytocin decreases sweet taste sensitivity in mice

Sinclair, M. S., Perea-Martinez, I., Abouyared, M., St. John, S. J. & Chaudhari, N., Mar 5 2015, In : Physiology and Behavior. 141, p. 103-110 8 p.

Research output: Contribution to journalArticle

Oxytocin
Sucrose
Taste Buds
Saccharin
Inosine Monophosphate
2014
20 Citations (Scopus)

Synaptic communication and signal processing among sensory cells in taste buds

Chaudhari, N., Aug 15 2014, In : Journal of Physiology. 592, 16, p. 3387-3392 6 p.

Research output: Contribution to journalArticle

Taste Buds
Communication
Adenosine Triphosphate
gamma-Aminobutyric Acid
Serotonin
2013
194 Citations (Scopus)

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

Taruno, A., Vingtdeux, V., Ohmoto, M., Ma, Z., Dvoryanchikov, G., Li, A., Adrien, L., Zhao, H., Leung, S., Abernethy, M., Koppel, J., Davies, P., Civan, M. M., Chaudhari, N., Matsumoto, I., Hellekant, G., Tordoff, M. G., Marambaud, P. & Foskett, J. K., Mar 14 2013, In : Nature. 495, 7440, p. 223-226 4 p.

Research output: Contribution to journalArticle

Ion Channels
Synaptic Transmission
Homeostasis
Taste Buds
Calcium
67 Citations (Scopus)

Functional Cell Types in Taste Buds Have Distinct Longevities

Perea-Martinez, I., Nagai, T. & Chaudhari, N., Jan 8 2013, In : PLoS One. 8, 1, e53399.

Research output: Contribution to journalArticle

Taste Buds
Deoxyuridine
palps
cells
Labeling
9 Citations (Scopus)

Gustatory sensory cells express a receptor responsive to protein breakdown products (GPR92)

Haid, D., Widmayer, P., Voigt, A., Chaudhari, N., Boehm, U. & Breer, H., Aug 1 2013, In : Histochemistry and Cell Biology. 140, 2, p. 137-145 9 p.

Research output: Contribution to journalArticle

Proteins
Protein Hydrolysates
Amino Acid Receptors
Enteroendocrine Cells
Taste Buds
2 Citations (Scopus)

Sweet umami: The twain shall meet

Chaudhari, N., Apr 1 2013, In : Journal of Physiology. 591, 7, p. 1597-1597 1 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
G-Protein-Coupled Receptors
2012
41 Citations (Scopus)

Adenosine enhances sweet taste through A2B receptors inthe taste bud

Dando, R., Dvoryanchikov, G., Pereira, E., Chaudhari, N. & Roper, S. D., Jan 4 2012, In : Journal of Neuroscience. 32, 1, p. 322-330 9 p.

Research output: Contribution to journalArticle

Taste Buds
Adenosine
Adenosine Triphosphate
Reverse Transcriptase Polymerase Chain Reaction
Neurotransmitter Agents
2011
39 Citations (Scopus)

GABA, its receptors, and GABAergic inhibition in mouse taste buds

Dvoryanchikov, G., Huang, Y. A., Barro, R., Chaudhari, N. & Roper, S. D., Apr 13 2011, In : Journal of Neuroscience. 31, 15, p. 5782-5791 10 p.

Research output: Contribution to journalArticle

Taste Buds
GABA Receptors
gamma-Aminobutyric Acid
GABA-A Receptors
Inhibition (Psychology)
38 Citations (Scopus)

Knocking out P2X receptors reduces transmitter secretion in taste buds

Huang, Y. A., Stone, L. M., Pereira, E., Yang, R., Kinnamon, J. C., Dvoryanchikov, G., Chaudhari, N., Finger, T. E., Kinnamon, S. C. & Roper, S. D., Sep 21 2011, In : Journal of Neuroscience. 31, 38, p. 13654-13661 8 p.

Research output: Contribution to journalArticle

Taste Buds
Adenosine Triphosphate
Purinergic P2X2 Receptors
Purinergic P2X3 Receptors
Knockout Mice
2010
27 Citations (Scopus)

Oxytocin signaling in mouse taste buds

Sinclair, M. S., Perea-Martinez, I., Dvoryanchikov, G., Yoshida, M., Nishimori, K., Roper, S. D. & Chaudhari, N., Oct 15 2010, In : PLoS One. 5, 8, e11980.

Research output: Contribution to journalArticle

Taste Buds
oxytocin
palps
Oxytocin
mice
384 Citations (Scopus)

The cell biology of taste

Chaudhari, N. & Roper, S. D., Aug 9 2010, In : Journal of Cell Biology. 190, 3, p. 285-296 12 p.

Research output: Contribution to journalArticle

Taste Buds
Cell Biology
Neuroepithelial Cells
Gene Expression
Food
2 Citations (Scopus)
Cell Biology
2009
28 Citations (Scopus)

Interaction between the second messengers cAMP and Ca2+ in mouse presynaptic taste cells

Roberts, C. D., Dvoryanchikov, G., Roper, S. D. & Chaudhari, N., Apr 15 2009, In : Journal of Physiology. 587, 8, p. 1657-1668 12 p.

Research output: Contribution to journalArticle

Second Messenger Systems
Cyclic AMP
Glutamate Decarboxylase
Taste Buds
Neuroglia
41 Citations (Scopus)

Inward rectifier channel, ROMK, is localized to the apical tips of glial-like cells in mouse taste buds

Dvoryanchilov, G., Sinclair, M. S., Perea-Martinez, I., Wang, T. & Chaudhari, N., Oct 15 2009, In : Journal of Comparative Neurology. 517, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

Taste Buds
Neuroglia
Kidney
Reverse Transcription
Tight Junctions
105 Citations (Scopus)

Taste receptors for umami: The case for multiple receptors

Chaudhari, N., Pereira, E. & Roper, S. D., Sep 1 2009, In : American Journal of Clinical Nutrition. 90, 3

Research output: Contribution to journalArticle

Taste Buds
Nucleotides
Glutamic Acid
Amino Acids
Guanosine Monophosphate
2008
56 Citations (Scopus)

Expression of Galpha14 in sweet-transducing taste cells of the posterior tongue

Tizzano, M., Dvoryanchikov, G., Barrows, J. K., Kim, S., Chaudhari, N. & Finger, T. E., Nov 13 2008, In : BMC Neuroscience. 9, 110.

Research output: Contribution to journalArticle

Tongue
Taste Buds
Gene Expression Profiling
Immune Sera
Immunohistochemistry
23 Citations (Scopus)

Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice

Kim, J. W., Roberts, C. D., Berg, S. A., Caicedo-Vierkant, D. A., Roper, S. D. & Chaudhari, N., May 7 2008, In : PLoS One. 3, 5, e2127.

Research output: Contribution to journalArticle

islets of Langerhans
cyclic AMP
Islets of Langerhans
Cyclic AMP
Transgenic Mice
48 Citations (Scopus)

Tonic activity of Gα-gustducin regulates taste cell responsivity

Clapp, T. R., Trubey, K. R., Vandenbeuch, A., Stone, L. M., Margolskee, R. F., Chaudhari, N. & Kinnamon, S. C., Nov 12 2008, In : FEBS Letters. 582, 27, p. 3783-3787 5 p.

Research output: Contribution to journalArticle

Transducin
Phosphoric Diester Hydrolases
Protein Kinase Inhibitors
Cyclic AMP-Dependent Protein Kinases
GTP-Binding Proteins
2007
68 Citations (Scopus)

Biogenic amine synthesis and uptake in rodent taste buds

Dvoryanchikov, G., Tomchik, S. M. & Chaudhari, N., Nov 20 2007, In : Journal of Comparative Neurology. 505, 3, p. 302-313 12 p.

Research output: Contribution to journalArticle

Taste Buds
Biogenic Amines
Rodentia
Norepinephrine
Serotonin
153 Citations (Scopus)

Breadth of tuning and taste coding in mammalian taste buds

Tomchik, S. M., Berg, S., Joung, W. K., Chaudhari, N. & Roper, S. D., Oct 3 2007, In : Journal of Neuroscience. 27, 40, p. 10840-10848 9 p.

Research output: Contribution to journalArticle

Taste Buds
Presynaptic Receptors
405 Citations (Scopus)

The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds

Huang, Y. J., Maruyama, Y., Dvoryanchikov, G., Pereira, E., Chaudhari, N. & Roper, S. D., Apr 10 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 15, p. 6436-6441 6 p.

Research output: Contribution to journalArticle

Taste Buds
Cell Communication
Adenosine Triphosphate
Purinergic P2 Receptors
Neurotransmitter Receptor
2006
42 Citations (Scopus)

Faithful expression of GFP from the PLCβ2 promoter in a functional class of taste receptor cells

Kim, J. W., Roberts, C., Maruyama, Y., Berg, S., Roper, S. D. & Chaudhari, N., Mar 1 2006, In : Chemical Senses. 31, 3, p. 213-219 7 p.

Research output: Contribution to journalArticle

phospholipase C
Type C Phospholipases
Protein C
Green Fluorescent Proteins
green fluorescent protein
209 Citations (Scopus)

Separate populations of receptor cells and presynaptic cells in mouse taste buds

DeFazio, R. A., Dvoryanchikov, G., Maruyama, Y., Kim, J. W., Pereira, E., Roper, S. D. & Chaudhari, N., Sep 7 2006, In : Journal of Neuroscience. 26, 15, p. 3971-3980 10 p.

Research output: Contribution to journalArticle

Taste Buds
Presynaptic Receptors
Population
Synaptosomal-Associated Protein 25
Phospholipases
35 Citations (Scopus)

Tastants evoke cAMP signal in taste buds that is independent of calcium signaling

Trubey, K. R., Culpepper, S., Maruyama, Y., Kinnamon, S. C. & Chaudhari, N., Aug 4 2006, In : American Journal of Physiology - Cell Physiology. 291, 2

Research output: Contribution to journalArticle

Taste Buds
Calcium Signaling
Calcium
Adenylyl Cyclases
Sucrose
100 Citations (Scopus)

Umami responses in mouse taste cells indicate more than one receptor

Maruyama, Y., Pereira, E., Margolskee, R. F., Chaudhari, N. & Roper, S. D., Feb 22 2006, In : Journal of Neuroscience. 26, 8, p. 2227-2234 8 p.

Research output: Contribution to journalArticle

Glutamic Acid
Taste Buds
Inosine Monophosphate
Type C Phospholipases
Nucleotides
2005
Taste Buds
Neurophysiology
Potassium Channels
Acids
4 Citations (Scopus)

Liposome-mediated transfection of mature taste cells

Landin, A. M., Kim, J. W. & Chaudhari, N., Oct 1 2005, In : Journal of Neurobiology. 65, 1, p. 12-21 10 p.

Research output: Contribution to journalArticle

Liposomes
Transfection
Taste Buds
Neuronal Cell Adhesion Molecules
Hydrolases
4 Citations (Scopus)

Multiple pathways for signaling glutamate taste in rodents

Chaudhari, N., Maruyama, Y., Roper, S. D. & Trubey, K., Jan 1 2005, In : Chemical Senses. 30 SUPPL. 1

Research output: Contribution to journalArticle

umami
electrophysiology
palps
transfection
glutamic acid
2004
57 Citations (Scopus)

Acid-Sensing Ion Channel-2 Is Not Necessary for Sour Taste in Mice

Richter, T. A., Dvoryanchikov, G. A., Roper, S. D. & Chaudhari, N., Apr 21 2004, In : Journal of Neuroscience. 24, 16, p. 4088-4091 4 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Taste Buds
Acids
Reverse Transcriptase Polymerase Chain Reaction
Ion Channels
81 Citations (Scopus)

Acid-sensitive two-pore domain potassium (K2P) channels in mouse taste buds

Richter, T. A., Dvoryanchikov, G. A., Chaudhari, N. & Roper, S. D., Sep 1 2004, In : Journal of Neurophysiology. 92, 3, p. 1928-1936 9 p.

Research output: Contribution to journalArticle

Taste Buds
Potassium Channels
Acids
Transducers
Ion Channels
2003
43 Citations (Scopus)

Adenylyl cyclase expression and modulation of cAMP in rat taste cells

Abaffy, T., Trubey, K. R. & Chaudhari, N., Jun 1 2003, In : American Journal of Physiology - Cell Physiology. 284, 6 53-6

Research output: Contribution to journalArticle

Adenylyl Cyclases
Rats
Modulation
Glutamic Acid
Proteins
2001
6 Citations (Scopus)

Molecular basis of the sweet tooth?

Chaudhari, N. & Kinnamon, S. C., Dec 22 2001, In : Lancet. 358, 9299, p. 2101-2102 2 p.

Research output: Contribution to journalArticle

2000
423 Citations (Scopus)

A metabotropic glutamate receptor variant functions as a taste receptor

Chaudhari, N., Landin, A. M. & Roper, S. D., Feb 1 2000, In : Nature Neuroscience. 3, 2, p. 113-119 7 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Sodium Glutamate
G-Protein-Coupled Receptors
Taste Buds
Dietary Proteins
1999
153 Citations (Scopus)

An optimized method for in situ hybridization with signal amplification that allows the detection of rare mRNAs

Yang, H., Wanner, I. B., Roper, S. D. & Chaudhari, N., Jan 1 1999, In : Journal of Histochemistry and Cytochemistry. 47, 4, p. 431-445 15 p.

Research output: Contribution to journalArticle

In Situ Hybridization
Messenger RNA
Alkaline Phosphatase
Transducin
RNA Probes
1998
63 Citations (Scopus)
Taste Buds
G-Protein-Coupled Receptors
Glutamic Acid
Sodium Glutamate
Adenosine
1997
62 Citations (Scopus)

Responses to glutamate in rat taste cells

Bigiani, A., Delay, R. J., Chaudhari, N., Kinnamon, S. C. & Roper, S. D., Jul 23 1997, In : Journal of Neurophysiology. 77, 6, p. 3048-3059 12 p.

Research output: Contribution to journalArticle

Glutamic Acid
Cations
Membranes
Taste Threshold
Taste Buds
1996
209 Citations (Scopus)

The taste of monosodium glutamate: Membrane receptors in taste buds

Chaudhari, N., Yang, H., Lamp, C., Delay, E., Cartford, C., Than, T. & Roper, S. D., Jun 20 1996, In : Journal of Neuroscience. 16, 12, p. 3817-3826 10 p.

Research output: Contribution to journalArticle

Taste Buds
Sodium Glutamate
Glutamate Receptors
Membranes
Tongue
1995
2 Citations (Scopus)

Muscular dysgenesis the role of calcium channels in muscle development.

Chaudhari, N., Jan 1 1995, In : Society of General Physiologists Series. 50, p. 115-123 9 p.

Research output: Contribution to journalArticle

electrophysiology
complementary DNA
calcium channels
Muscle Development
muscle development
1993
58 Citations (Scopus)

mRNA for cardiac calcium channel is expressed during development of skeletal muscle

Chaudhari, N. & Beam, K. G., Dec 1 1993, In : Developmental Biology. 155, 2, p. 507-515 9 p.

Research output: Contribution to journalArticle

Calcium Channels
Skeletal Muscle
Messenger RNA
Contractile Proteins
Skeletal Muscle Fibers