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Nagi Ayad

Associate Professor

  • 1464 Citations
19952019
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Anaphase-Promoting Complex-Cyclosome Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Cell Cycle Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Medulloblastoma Medicine & Life Sciences
Mitosis Medicine & Life Sciences

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Projects 2006 2019

Epigenetic and Kinase Pathway Interactions in Medulloblastoma

Ayad, N.

National Institutes of Health

8/1/17 → 7/31/19

Project: Research project

Medulloblastoma
Epigenomics
Phosphotransferases
Hedgehogs
Chromatin

The Anaphase Promoting Complex and Cell Cycle Exit

Ayad, N.

National Institutes of Health

9/1/10 → 5/31/15

Project: Research project

Anaphase-Promoting Complex-Cyclosome
Cell Cycle
Ubiquitin
Proteolysis
Ligases

Small-molecule Inhibitors of Wee1 Degradation and Mitotic Entry

Ayad, N.

National Institutes of Health

6/15/06 → 6/14/09

Project: Research project

Cell Proliferation
Mitosis
Cell Cycle
Neoplasms
Proteasome Inhibitors

Research Output 1995 2019

A CK1a Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma

Rodriguez-Blanco, J., Li, B., Long, J., Shen, C., Yang, F., Orton, D., Collins, S., Kasahara, N., Ayad, N., McCrea, H. J., Roussel, M. F., Weiss, W. A., Capobianco, A. J. & Robbins, D. J., Feb 15 2019, In : Clinical Cancer Research. 25, 4, p. 1379-1388 10 p.

Research output: Contribution to journal › Article

Casein Kinases
Medulloblastoma
Hedgehogs
Brain
Pharmaceutical Preparations

Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner 06 Biological Sciences 0604 Genetics 11 Medical and Health Sciences 1114 Paediatrics and Reproductive Medicine

Winterbottom, E. F., Moroishi, Y., Halchenko, Y., Armstrong, D. A., Beach, P. J., Nguyen, Q. P., Capobianco, A. J., Ayad, N., Marsit, C. J., Li, Z., Karagas, M. R. & Robbins, D. J., Feb 28 2019, In : Environmental Health: A Global Access Science Source. 18, 1, 18.

Research output: Contribution to journal › Article

Open Access
Reproductive Medicine
Biological Science Disciplines
Medical Genetics
Arsenic
Epigenomics
2 Citations (Scopus)

Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury

Rudman, M. D., Choi, J. S., Lee, H. E., Tan, S. K., Ayad, N. & Lee, J., Nov 1 2018, In : Experimental Neurology. 309, p. 181-192 12 p.

Research output: Contribution to journal › Article

Spinal Cord Injuries
Inflammation
Epigenomics
Spinal Cord
Cytokines
2 Citations (Scopus)

Drug and disease signature integration identifies synergistic combinations in glioblastoma

Stathias, V., Jermakowicz, A. M., Maloof, M. E., Forlin, M., Walters, W., Suter, R. K., Durante, M. A., Williams, S. L., William Harbour, J., Volmar, C. H., Lyons, N. J., Wahlestedt, C. R., Graham, R. M., Ivan, M. E., Komotar, R. J., Sarkaria, J. N., Subramanian, A., Golub, T. R., Schuerer, S. C. & Ayad, N., Dec 1 2018, In : Nature Communications. 9, 1, 5315.

Research output: Contribution to journal › Article

Glioblastoma
drugs
signatures
Gene expression
Genes
8 Citations (Scopus)

Drug repositioning in glioblastoma: A pathway perspective

Tan, S. K., Jermakowicz, A., Mookhtiar, A. K., Nemeroff, C., Schuerer, S. C. & Ayad, N., Mar 16 2018, In : Frontiers in Pharmacology. 9, MAR, 218.

Research output: Contribution to journal › Review article

Drug Repositioning
Glioblastoma
Cell Death
Therapeutics
Drug Delivery Systems