Projects per year
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- 1 Similar Profiles
Pancreatic Neoplasms
Medicine & Life Sciences
Cathepsin B
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Goats
Medicine & Life Sciences
Mouth Neoplasms
Medicine & Life Sciences
Cells
Chemical Compounds
Epithelial-Mesenchymal Transition
Medicine & Life Sciences
gemcitabine
Medicine & Life Sciences
Network
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Projects 2016 2018
- 1 Finished
Targeting cytokine mediated CREB activation in pancreatic cancer
7/5/16 → 6/30/18
Project: Research project › Exploratory/Developmental Grants
Response Elements
Pancreatic Neoplasms
Cyclic AMP
Cytokines
Adenocarcinoma
Research Output 2001 2017
Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth
Messaggio, F., Mendonsa, A. M., Castellanos, J., Nagathihalli, N. S., Gorden, L., Merchant, N. B. & VanSaun, M. N. Oct 17 2017 In : Oncotarget. 8, 49, p. 85378-85391 14 p.Research output: Contribution to journal › Article
Adiponectin Receptors
Adipokines
Adiponectin
Leptin
Pancreatic Neoplasms
9
Citations
Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells
Nagathihalli, N. S., Castellanos, J. A., Van Saun, M. N., Dai, X., Ambrose, M., Guo, Q., Xiong, Y. & Merchant, N. B. 2016 In : Oncotarget. 7, 40, p. 65982-65992 11 p.Research output: Contribution to journal › Article
Pancreatic Stellate Cells
STAT3 Transcription Factor
Interleukin-6
Adenocarcinoma
Neoplasms
14
Citations
Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response
Walsh, A. J., Castellanos, J. A., Nagathihalli, N. S., Merchant, N. B. & Skala, M. C. Oct 22 2015 (Accepted/In press) In : Pancreas.Research output: Contribution to journal › Article
Organoids
Optical Imaging
Pancreatic Neoplasms
Pharmaceutical Preparations
Pharmacological Biomarkers
37
Citations
Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer
Nagathihalli, N. S., Castellanos, J. A., Shi, C., Beesetty, Y., Reyzer, M. L., Caprioli, R., Chen, X., Walsh, A. J., Skala, M. C., Moses, H. L. & Merchant, N. B. Dec 1 2015 In : Gastroenterology. 149, 7, p. 1932-1943 12 p.Research output: Contribution to journal › Article
STAT3 Transcription Factor
Tumor Microenvironment
Pancreatic Neoplasms
gemcitabine
Pharmaceutical Preparations
Altered SignaLing Pathways and Potential Therapeutic Targets in Pancreatic Cancer
Castellanos, J., NagathihalLi, N. & Merchant, N. Jan 1 2014 Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 2265-2273 9 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
gemcitabine
Neoplastic Stem Cells
Pancreatic Neoplasms
Transforming Growth Factor beta
Adenocarcinoma