Mingjiang Xu

Associate Professor

  • 4634 Citations
19982023

Research output per year

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Research Output

  • 4634 Citations
  • 95 Article
  • 5 Letter
  • 4 Review article
  • 3 Comment/debate
2020

The Role of ASXL1/2 and Their Associated Proteins in Malignant Hematopoiesis

Zhang, P., Xu, M. & Yang, F. C., Mar 1 2020, In : Current Stem Cell Reports. 6, 1, p. 6-15 10 p.

Research output: Contribution to journalReview article

2019

ASXL1 alteration cooperates with JAK2V617F to accelerate myelofibrosis

Guo, Y., Zhou, Y., Yamatomo, S., Yang, H., Zhang, P., Chen, S., Nimer, S. D., Zhao, Z. J., Xu, M., Bai, J. & Yang, F. C., May 1 2019, In : Leukemia. 33, 5, p. 1287-1291 5 p.

Research output: Contribution to journalLetter

5 Scopus citations

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216), (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., Jermakowicz, A. M., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D. G., Watts, J., Vega, F. & Nimer, S. D., Jan 14 2019, In : Cancer Cell. 35, 1, 1 p.

Research output: Contribution to journalComment/debate

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Luo, H., Zhu, G., Xu, J., Lai, Q., Yan, B., Guo, Y., Fung, T. K., Zeisig, B. B., Cui, Y., Zha, J., Cogle, C., Wang, F., Xu, B., Yang, F. C., Li, W., So, C. W. E., Qiu, Y., Xu, M. & Huang, S., Dec 9 2019, In : Cancer Cell. 36, 6, p. 645-659.e8

Research output: Contribution to journalArticle

1 Scopus citations

Six1 regulates leukemia stem cell maintenance in acute myeloid leukemia

Chu, Y., Chen, Y., Li, M., Shi, D., Wang, B., Lian, Y., Cheng, X., Wang, X., Xu, M., Cheng, T., Shi, J. & Yuan, W., Jul 1 2019, In : Cancer Science. 110, 7, p. 2200-2210 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

A novel ASXL1–OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies

Inoue, D., Fujino, T., Sheridan, P., Zhang, Y. Z., Nagase, R., Horikawa, S., Li, Z., Matsui, H., Kanai, A., Saika, M., Yamaguchi, R., Kozuka-Hata, H., Kawabata, K. C., Yokoyama, A., Goyama, S., Inaba, T., Imoto, S., Miyano, S., Xu, M., Yang, F-C. & 2 others, Oyama, M. & Kitamura, T., Mar 3 2018, (Accepted/In press) In : Leukemia. p. 1-11 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Cardiac Sca-1+ cells are not intrinsic stem cells for myocardial development, renewal, and repair

Zhang, L., Sultana, N., Yan, J., Yang, F., Chen, F., Chepurko, E., Yang, F. C., Du, Q., Zangi, L., Xu, M., Bu, L. & Cai, C. L., Jan 1 2018, In : Circulation. 138, 25, p. 2919-2930 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathais, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schuerer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F-C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Jun 11 2018, In : Cancer Cell. 33, 6, p. 1111-1127.e5

Research output: Contribution to journalArticle

8 Scopus citations

Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy

Zhang, P., He, F., Bai, J., Yamamoto, S., Chen, S., Zhang, L., Sheng, M., Zhang, L., Guo, Y., Man, N., Yang, H., Wang, S., Cheng, T., Nimer, S. D., Zhou, Y., Xu, M., Wang, Q. F. & Yang, F. C., Dec 3 2018, In : Journal of Clinical Investigation. 128, 12, p. 5383-5398 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML

Sayar, H., Liu, Y., Gao, R., Zaid, M. A., Cripe, L. D., Weisenbach, J., Sargent, K. J., Nassiri, M., Li, L., Konig, H., Suvannasankha, A., Pan, F., Shanmugam, R., Goswami, C., Kapur, R., Xu, M. & Scott Boswell, H., Jan 1 2018, In : Oncotarget. 9, 5, p. 5703-5715 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia

Luo, H., Wang, F., Zha, J., Li, H., Yan, B., Du, Q., Yang, F., Sobh, A., Vulpe, C., Drusbosky, L., Cogle, C., Chepelev, I., Xu, B., Nimer, S. D., Licht, J., Qiu, Y., Chen, B., Xu, M. & Huang, S., Aug 23 2018, In : Blood. 132, 8, p. 837-848 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216) (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Nov 12 2018, In : Cancer Cell. 34, 5, 1 p.

Research output: Contribution to journalComment/debate

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Yang, H., Kurtenbach, S., Guo, Y., Lohse, I., Durante, M. A., Li, J., Li, Z., Al-Ali, H., Li, L., Chen, Z., Field, M. G., Zhang, P., Chen, S., Yamamoto, S., Li, Z., Zhou, Y., Nimer, S. D., William Harbour, J., Wahlestedt, C., Xu, M. & 1 others, Yang, F. C., Jan 18 2018, In : Blood. 131, 3, p. 328-341 14 p.

Research output: Contribution to journalArticle

37 Scopus citations

Idh1/2 mutations sensitize acute myeloid leukemia to parp inhibition and this is reversed by idh1/2-mutant inhibitors

Molenaar, R. J., Radivoyevitch, T., Nagata, Y., Khurshed, M., Przychodzen, B., Makishima, H., Xu, M., Bleeker, F. E., Wilmink, J. W., Carraway, H. E., Mukherjee, S., Sekeres, M. A., van Noorden, C. J. F. & Maciejewski, J. P., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1705-1715 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem and progenitor cell fates

Zhang, P., Chen, Z., Li, R., Guo, Y., Shi, H., Bai, J., Yang, H., Sheng, M., Li, Z., Li, Z., Li, J., Chen, S., Yuan, W., Cheng, T., Xu, M., Zhou, Y. & Yang, F. C., Dec 1 2018, In : Cell Discovery. 4, 1, 4.

Research output: Contribution to journalArticle

10 Scopus citations

Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway

Palam, L. R., Mali, R. S., Ramdas, B., Srivatsan, S. N., Visconte, V., Tiu, R. V., Vanhaesebroeck, B., Roers, A., Gerbaulet, A., Xu, M., Janga, S. C., Takemoto, C. M., Paczesny, S. & Kapur, R., Feb 22 2018, In : JCI Insight. 3, 4

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo

Guo, Y., Yang, H., Chen, S., Zhang, P., Li, R., Nimer, S. D., Harbour, J. W., Xu, M. & Yang, F. C., Aug 1 2018, In : Leukemia. 32, 8, p. 1834-1837 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells

Guallar, D., Bi, X., Pardavila, J. A., Huang, X., Saenz, C., Shi, X., Zhou, H., Faiola, F., Ding, J., Haruehanroengra, P., Yang, F., Li, D., Sanchez-Priego, C., Saunders, A., Pan, F., Valdes, V. J., Kelley, K., Blanco, M. G., Chen, L., Wang, H. & 5 others, Sheng, J., Xu, M., Fidalgo, M., Shen, X. & Wang, J., Mar 1 2018, In : Nature genetics. 50, 3, p. 443-451 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

TET2 Loss Dysregulates the Behavior of Bone Marrow Mesenchymal Stromal Cells and Accelerates Tet2−/−-Driven Myeloid Malignancy Progression

Li, R., Zhou, Y., Cao, Z., Liu, L., Wang, J., Chen, Z., Xing, W., Chen, S., Bai, J., Yuan, W., Cheng, T., Xu, M., Yang, F-C. & Zhao, Z., Jan 1 2018, In : Stem Cell Reports. 10, 1, p. 166-179 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)

Chu, Y., Zhao, Z., Sant, D. W., Zhu, G., Greenblatt, S. M., Liu, L., Wang, J., Cao, Z., Tho, J. C., Chen, S., Liu, X., Zhang, P., Maciejewski, J. P., Nimer, S., Wang, G., Yuan, W., Yang, F. C. & Xu, M., Jun 2018, In : Genomics, Proteomics and Bioinformatics. 16, 3, p. 172-186 15 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in fanconi anemia

Zhou, Y., He, Y., Xing, W., Zhang, P., Shi, H., Chen, S., Shi, J., Bai, J., Rhodes, S. D., Zhang, F., Yuan, J., Yang, X., Zhu, X., Li, Y., Hanenberg, H., Xu, M., Robertson, K. A., Yuan, W., Nalepa, G., Cheng, T. & 2 others, Clapp, D. W. & Yang, F. C., Jan 1 2017, In : Haematologica. 102, 6, p. 1017-1027 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis

Li, Z., Zhang, P., Yan, A., Guo, Z., Ban, Y., Li, J., Chen, S., Yang, H., He, Y., Li, J., Guo, Y., Zhang, W., Hajiramezanali, E., An, H., Fajardo, D., William Harbour, J., Ruan, Y., Nimer, S. D., Yu, P., Chen, X. & 2 others, Xu, M. & Yang, F. C., Jan 2017, In : Science Advances. 3, 1, e1601602.

Research output: Contribution to journalArticle

15 Scopus citations

Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner

Man, N., Tan, Y., Sun, X. J., Liu, F., Cheng, G., Greenblatt, S. M., Martinez, C., Karl, D. L., Ando, K., Sun, M., Hou, D., Chen, B., Xu, M., Yang, F-C., Chen, Z., Chen, S., Nimer, S. D. & Wang, L., May 18 2017, In : Blood. 129, 20, p. 2782-2792 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Loss of Asxl2 leads to myeloid malignancies in mice

Li, J., He, F., Zhang, P., Chen, S., Shi, H., Sun, Y., Guo, Y., Yang, H., Man, N., Greenblatt, S., Li, Z., Guo, Z., Zhou, Y., Wang, L., Morey, L., Williams, S., Chen, X., Wang, Q. T., Nimer, S. D., Yu, P. & 3 others, Wang, Q. F., Xu, M. & Yang, F. C., Jun 8 2017, In : Nature communications. 8, 15456.

Research output: Contribution to journalArticle

10 Scopus citations

Loss of p300 accelerates MDS-associated leukemogenesis

Cheng, G., Liu, F., Asai, T., Lai, F., Man, N., Xu, H., Chen, S., Greenblatt, S., Hamard, P. J., Ando, K., Chen, X., Wang, L., Martinez, C., Tadi, M., Wang, L., Xu, M., Yang, F. C., Shiekhattar, R. & Nimer, S. D., Jan 6 2017, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

11 Scopus citations

PBX3 is essential for leukemia stem cell maintenance in MLL-rearranged leukemia

Guo, H., Chu, Y., Wang, L., Chen, X., Chen, Y., Cheng, H., Zhang, L., Zhou, Y., Yang, F. C., Cheng, T., Xu, M., Zhang, X., Zhou, J. & Yuan, W., Jul 15 2017, In : International Journal of Cancer. 141, 2, p. 324-335 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Cimmino, L., Dolgalev, I., Wang, Y., Yoshimi, A., Martin, G. H., Wang, J., Ng, V., Xia, B., Witkowski, M. T., Mitchell-Flack, M., Grillo, I., Bakogianni, S., Ndiaye-Lobry, D., Martín, M. T., Guillamot, M., Banh, R. S., Xu, M., Figueroa, M., Dickins, R. A., Abdel-Wahab, O. & 4 others, Park, C. Y., Tsirigos, A., Neel, B. G. & Aifantis, I., Sep 7 2017, In : Cell. 170, 6, p. 1079-1095.e20

Research output: Contribution to journalArticle

165 Scopus citations

Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis

Li, X., Yao, B., Chen, L., Kang, Y., Li, Y., Cheng, Y., Li, L., Lin, L., Wang, Z., Wang, M., Pan, F., Dai, Q., Zhang, W., Wu, H., Shu, Q., Qin, Z., He, C., Xu, M. & Jin, P., Jun 29 2017, In : Nature communications. 8, 15903.

Research output: Contribution to journalArticle

27 Scopus citations

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells

Pan, F., Wingo, T. S., Zhao, Z., Gao, R., Makishima, H., Qu, G., Lin, L., Yu, M., Ortega, J. R., Wang, J., Nazha, A., Chen, L., Yao, B., Liu, C., Chen, S., Weeks, O., Ni, H., Phillips, B. L., Huang, S., Wang, J. & 8 others, He, C., Li, G. M., Radivoyevitch, T., Aifantis, I., MacIejewski, J. P., Yang, F-C., Jin, P. & Xu, M., Jan 1 2017, In : Nature Communications. 8, 15102.

Research output: Contribution to journalArticle

33 Scopus citations

Tyrosine kinase inhibitors targeting FLT3 in the treatment of acute myeloid leukemia

Chen, Y., Pan, Y., Guo, Y., Zhao, W., Ho, W. T., Wang, J., Xu, M., Yang, F-C. & Zhao, Z. J., Jun 1 2017, In : Stem Cell Investigation. 4, 6, 48.

Research output: Contribution to journalReview article

16 Scopus citations
2016

ASXL1 plays an important role in erythropoiesis

Shi, H., Yamamoto, S., Sheng, M., Bai, J., Zhang, P., Chen, R., Chen, S., Shi, L., Abdel-Wahab, O., Xu, M., Zhou, Y. & Yang, F. C., Jun 29 2016, In : Scientific reports. 6, 28789.

Research output: Contribution to journalArticle

19 Scopus citations

Loss of Asxl1 alters self-renewal and cell fate of bone marrow stromal cell, leading to bohring-opitz-like syndrome in mice

Zhang, P., Xing, C., Rhodes, S. D., He, Y., Deng, K., Li, Z., He, F., Zhu, C., Nguyen, L., Zhou, Y., Chen, S., Mohammad, K. S., Guise, T. A., Abdel-Wahab, O., Xu, M., Wang, Q. F. & Yang, F. C., Jun 14 2016, In : Stem Cell Reports. 6, 6, p. 914-925 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

Zhang, F., Hammack, C., Ogden, S. C., Cheng, Y., Lee, E. M., Wen, Z., Qian, X., Nguyen, H. N., Li, Y., Yao, B., Xu, M., Xu, T., Chen, L., Wang, Z., Feng, H., Huang, W. K., Yoon, K. J., Shan, C., Huang, L., Qin, Z. & 10 others, Christian, K. M., Shi, P. Y., Xu, M., Xia, M., Zheng, W., Wu, H., Song, H., Tang, H., Ming, G. L. & Jin, P., Oct 14 2016, In : Nucleic Acids Research. 44, 18, p. 8610-8620 11 p.

Research output: Contribution to journalArticle

80 Scopus citations

Research advances in the mutation of TET2 gene in myeloid maligancies

Li, R., Xu, M., Yang, F-C. & Zhou, Y., Oct 30 2016, In : Acta Academiae Medicinae Sinicae. 38, 5, p. 583-588 6 p.

Research output: Contribution to journalReview article

Rheb1 promotes tumor progression through mTORC1 in MLL-AF9- initiated murine acute myeloid leukemia

Gao, Y., Gao, J., Li, M., Zheng, Y., Wang, Y., Zhang, H., Wang, W., Chu, Y., Wang, X., Xu, M., Cheng, T., Ju, Z. & Yuan, W., Jan 1 2016, In : Journal of Hematology and Oncology. 9, 1, 36.

Research output: Contribution to journalArticle

8 Scopus citations

The catalytic activity of TET2 is essential for its myeloid malignancy-suppressive function in hematopoietic stem/progenitor cells

Zhao, Z., Chen, S., Zhu, X., Pan, F., Li, R., Zhou, Y., Yuan, W., Ni, H., Yang, F-C. & Xu, M., Aug 1 2016, In : Leukemia. 30, 8, p. 1784-1788 5 p.

Research output: Contribution to journalLetter

12 Scopus citations
2015

Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice

Zhao, Z., Chen, L., Dawlaty, M. M., Pan, F., Weeks, O., Zhou, Y., Cao, Z., Shi, H., Wang, J., Lin, L., Chen, S., Yuan, W., Qin, Z., Ni, H., Nimer, S. D., Yang, F. C., Jaenisch, R., Jin, P. & Xu, M., Nov 24 2015, In : Cell Reports. 13, 8, p. 1692-1704 13 p.

Research output: Contribution to journalArticle

47 Scopus citations

Hyperactive RAS/PI3-K/MAPK signaling cascade in migration and adhesion of Nf1 haploinsufficient mesenchymal stem/progenitor cells

Zhou, Y., He, Y., Sharma, R., Xing, W., Estwick, S. A., Wu, X., Rhodes, S. D., Xu, M. & Yang, F. C., Jan 1 2015, In : International journal of molecular sciences. 16, 6, p. 12345-12359 15 p., A031.

Research output: Contribution to journalArticle

2 Scopus citations

Nf1 haploinsufficiency alters myeloid lineage commitment and function, leading to deranged skeletal homeostasis

Rhodes, S. D., Yang, H., Dong, R., Menon, K., He, Y., Li, Z., Chen, S., Staser, K. W., Jiang, L., Wu, X., Yang, X., Peng, X., Mohammad, K. S., Guise, T. A., Xu, M. & Yang, F. C., Oct 1 2015, In : Journal of Bone and Mineral Research. 30, 10, p. 1840-1851 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Phosphoinositide-dependent kinase 1 regulates leukemia stem cell maintenance in MLL-AF9-induced murine acute myeloid leukemia

Hu, T., Li, C., Zhang, Y., Wang, L., Peng, L., Cheng, H., Wang, W., Chu, Y., Xu, M., Cheng, T. & Yuan, W., Apr 17 2015, In : Biochemical and Biophysical Research Communications. 459, 4, p. 692-698 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Resident c-kit + cells in the heart are not cardiac stem cells

Sultana, N., Zhang, L., Yan, J., Chen, J., Cai, W., Razzaque, S., Jeong, D., Sheng, W., Bu, L., Xu, M., Huang, G. Y., Hajjar, R. J., Zhou, B., Moon, A. & Cai, C. L., Oct 30 2015, In : Nature communications. 6, 8701.

Research output: Contribution to journalArticle

150 Scopus citations

The TET2 interactors and their links to hematological malignancies

Pan, F., Weeks, O., Yang, F-C. & Xu, M., Jun 1 2015, In : IUBMB Life. 67, 6, p. 438-445 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice

Wang, J., Li, Z., He, Y., Pan, F., Chen, S., Rhodes, S., Nguyen, L., Yuan, J., Jiang, L., Yang, X., Weeks, O., Liu, Z., Zhou, J., Ni, H., Cai, C. L., Xu, M. & Yang, F. C., Jan 23 2014, In : Blood. 123, 4, p. 541-553 13 p.

Research output: Contribution to journalArticle

84 Scopus citations

Rictor/mammalian target of rapamycin 2 regulates the development of notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3

Hua, C., Guo, H., Bu, J., Zhou, M., Cheng, H., He, F., Wang, J., Wang, X., Zhang, Y., Wang, Q., Zhou, J., Cheng, T., Xu, M. & Yuan, W., Dec 1 2014, In : Experimental Hematology. 42, 12, p. 1031-1040.e4

Research output: Contribution to journalArticle

6 Scopus citations

Whole exome sequencing reveals concomitant mutations of multiple FA genes in individual Fanconi anemia patients

Chang, L., Yuan, W., Zeng, H., Zhou, Q., Wei, W., Zhou, J., Li, M., Wang, X., Xu, M., Yang, F., Yang, Y., Cheng, T. & Zhu, X., May 15 2014, In : BMC Medical Genomics. 7, 1, 24.

Research output: Contribution to journalArticle

7 Scopus citations
2013
6 Scopus citations

Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development

Dawlaty, M. M., Breiling, A., Le, T., Raddatz, G., Barrasa, M. I., Cheng, A. W., Gao, Q., Powell, B. E., Li, Z., Xu, M., Faull, K. F., Lyko, F. & Jaenisch, R., Feb 11 2013, In : Developmental Cell. 24, 3, p. 310-323 14 p.

Research output: Contribution to journalArticle

260 Scopus citations

Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurobromin-decient mice

Sharma, R., Wu, X., Rhodes, S. D., Chen, S., He, Y., Yuan, J., Li, J., Yang, X., Li, X., Jiang, L., Kim, E. T., Stevenson, D. A., Viskochil, D., Xu, M. & Yang, F. C., Dec 1 2013, In : Human molecular genetics. 22, 23, p. 4818-4828 11 p., ddt333.

Research output: Contribution to journalArticle

26 Scopus citations

Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model

Rhodes, S. D., Wu, X., He, Y., Chen, S., Yang, H., Staser, K. W., Wang, J., Zhang, P., Jiang, C., Yokota, H., Dong, R., Peng, X., Yang, X., Murthy, S., Azhar, M., Mohammad, K. S., Xu, M., Guise, T. A. & Yang, F. C., Dec 1 2013, In : Journal of Bone and Mineral Research. 28, 12, p. 2476-2489 14 p.

Research output: Contribution to journalArticle

28 Scopus citations