Mike Schmidt &ndash; Research Output

2019

3 Citations (Scopus)

A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease

Alzheimer's Disease Sequencing Project, Mar 1 2019, In : Alzheimer's and Dementia. 15, 3, p. 441-452 12 p.

Research output: Contribution to journal › Article

Open Access

Alzheimer Disease

Hispanic Americans

Genome-Wide Association Study

Case-Control Studies

Alzheimer disease type 2

2018

1 Citation (Scopus)

Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project

Alzheimer's Disease Sequencing Project (ADSP), Jan 1 2018, (Accepted/In press) In : Genomics.

Research output: Contribution to journal › Article

Quality Control

Alzheimer Disease

Genotype

Genome

Atlases

17 Citations (Scopus)

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

Alzheimer’s Disease Sequencing Project, Jan 1 2018, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journal › Article

Exome

Alzheimer Disease

Hispanic Americans

Genes

Long Noncoding RNA

2016

21 Citations (Scopus)

GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis

Hussman, J. P., Beecham, A. H., Schmidt, M., Martin, E. R., McCauley, J. L., Vance, J. M., Haines, J. L. & Pericak-Vance, M. A., Jun 9 2016, (Accepted/In press) In : Genes and Immunity.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Multiple Sclerosis

T-Lymphocytes

Genes

Noise

2015

20 Citations (Scopus)

Targeted massively parallel sequencing of autism spectrum disorder-associated genes in a case control cohort reveals rare loss-of-function risk variants

Griswold, A., Dueker, N. D., Van Booven, D., Rantus, J. A., Jaworski, J. M., Slifer, S. H., Schmidt, M., Hulme, W., Konidari, I., Whitehead, P. L., Cuccaro, M., Martin, E. R., Haines, J. L., Gilbert, J., Hussman, J. P. & Pericak-Vance, M. A., Jul 7 2015, In : Molecular Autism. 6, 1, 43.

Research output: Contribution to journal › Article

High-Throughput Nucleotide Sequencing

Genes

Genome-Wide Association Study

Autism Spectrum Disorder

Mutation

2014

93 Citations (Scopus)

Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders

Cukier, H. N., Dueker, N. D., Slifer, S. H., Lee, J. M., Whitehead, P. L., Lalanne, E., Leyva, N., Konidari, I., Gentry, R. C., Hulme, W. F., Booven, D. V., Mayo, V., Hofmann, N. K., Schmidt, M., Martin, E. R., Haines, J. L., Cuccaro, M., Gilbert, J. & Pericak-Vance, M. A., Jan 10 2014, In : Molecular Autism. 5, 1, 1.

Research output: Contribution to journal › Article

Exome

Autistic Disorder

Genes

Neurodevelopmental Disorders

Autism Spectrum Disorder

2013

18 Citations (Scopus)

Evaluating Mitochondrial DNA Variation in Autism Spectrum Disorders

Hadjixenofontos, A., Schmidt, M., Whitehead, P. L., Konidari, I., Hedges, D. J., Wright, H. H., Abramson, R. K., Menon, R., Williams, S. M., Cuccaro, M., Haines, J. L., Gilbert, J., Pericak-Vance, M. A., Martin, E. R. & McCauley, J. L., Jan 1 2013, In : Annals of Human Genetics. 77, 1, p. 9-21 13 p.

Research output: Contribution to journal › Article

Mitochondrial DNA

Autistic Disorder

Autism Spectrum Disorder

Genome-Wide Association Study

Fathers

7 Citations (Scopus)

Pathway-PDT: A flexible pathway analysis tool for nuclear families

Park, Y. S., Schmidt, M., Martin, E. R., Pericak-Vance, M. A. & Chung, R. H., Sep 4 2013, In : BMC Bioinformatics. 14, 1, 267.

Research output: Contribution to journal › Article

Pedigree

Nuclear Family

Pathway

Genes

Genome-Wide Association Study

2012

95 Citations (Scopus)

Evaluation of copy number variations reveals novel candidate genes in autism spectrum disorder-associated pathways

Griswold, A., Ma, D., Cukier, H. N., Nations, L. D., Schmidt, M., Chung, R. H., Jaworski, J. M., Salyakina, D., Konidari, I., Whitehead, P. L., Wright, H. H., Abramson, R. K., Williams, S. M., Menon, R., Martin, E. R., Haines, J. L., Gilbert, J., Cuccaro, M. & Pericak-Vance, M. A., Aug 1 2012, In : Human Molecular Genetics. 21, 15, p. 3513-3523 11 p., dds164.

Research output: Contribution to journal › Article

GABA Receptors

Genes

GABA Plasma Membrane Transport Proteins

Neural Pathways

Genetic Loci

2011

1 Citation (Scopus)

CAPL: An efficient association software package using family and case-control data and accounting for population stratification

Chung, R. H., Schmidt, M. & Martin, E. R., May 25 2011, In : BMC Bioinformatics. 12, 201.

Research output: Contribution to journal › Article

Case-control Data

Stratification

Software Package

Software packages

Genome

2010

15 Citations (Scopus)

CAPL: A novel association test using case-control and family data and accounting for population stratification

Chung, R. H., Schmidt, M., Morris, R. W. & Martin, E. R., Nov 1 2010, In : Genetic Epidemiology. 34, 7, p. 747-755 9 p.

Research output: Contribution to journal › Article

Population

Sample Size

Siblings

Genotype

Genome-Wide Association Study

50 Citations (Scopus)

SeqEM: An adaptive genotype-calling approach for next-generation sequencing studies

Martin, E. R., Kinnamon, D. D., Schmidt, M., Powell, E. H., Zuchner, S. L. & Morris, R. W., Nov 1 2010, In : Bioinformatics. 26, 22, p. 2803-2810 8 p., btq526.

Research output: Contribution to journal › Article

Genotype

Sequencing

Nucleotides

Classifiers

Error Rate

2009

63 Citations (Scopus)

Exome sequencing of a multigenerational human pedigree

Hedges, D., Burges, D., Powell, E., Almonte, C., Huang, J., Young, S., Boese, B., Schmidt, M., Pericak-Vance, M. A., Martin, E. R., Zhang, X., Harkins, T. T. & Zuchner, S. L., Dec 1 2009, In : PLoS One. 4, 12, e8232.

Research output: Contribution to journal › Article

Exome

Pedigree

pedigree

Genotype

genotype

2008

The future is now - Will the real disease gene please stand up?

Martin, E. R. & Schmidt, M., Mar 1 2008, In : Human Heredity. 66, 2, p. 127-135 9 p.

Research output: Contribution to journal › Article

Genes

Pedigree

Alleles

Genome

Viverridae

2007

4 Citations (Scopus)

Increased efficiency of case-control association analysis by using allele-sharing and covariate information

Schmidt, S., Schmidt, M., Qin, X., Martin, E. R. & Hauser, E. R., Dec 1 2007, In : Human Heredity. 65, 3, p. 154-165 12 p.

Research output: Contribution to journal › Article

Information Dissemination

Quantitative Trait Loci

Alleles

Gene-Environment Interaction

Case-Control Studies

6 Citations (Scopus)

Interpreting analyses of continuous covariates in affected sibling pair linkage studies

Schmidt, S., Qin, X., Schmidt, M., Martin, E. R. & Hauser, E. R., Sep 1 2007, In : Genetic Epidemiology. 31, 6, p. 541-552 12 p.

Research output: Contribution to journal › Article

Quantitative Trait Loci

Disease Susceptibility

Lod Score

Macular Degeneration

Genes

2006

5 Citations (Scopus)

Linkage analysis with gene-environment interaction: Model illustration and performance of ordered subset analysis

Schmidt, S., Schmidt, M., Qin, X., Martin, E. R. & Hauser, E. R., Jul 1 2006, In : Genetic Epidemiology. 30, 5, p. 409-422 14 p.

Research output: Contribution to journal › Article

Gene-Environment Interaction

Genotype

Lod Score

Genetic Heterogeneity

Genetic Models

2005

37 Citations (Scopus)

Extension of the SIMLA package for generating pedigrees with complex inheritance patterns: Environmental covariates, gene-gene and gene-environment interaction

Schmidt, M., Martin, E. R., Hauser, E. R. & Schmidt, S., Jun 6 2005, In : Statistical Applications in Genetics and Molecular Biology. 4, 1, 15.

Research output: Contribution to journal › Article

Gene-environment Interaction

Inheritance Patterns

Gene-Environment Interaction

Pedigree

Linkage

66 Citations (Scopus)

Linkage disequilibrium inflates type I error rates in multipoint linkage analysis when parental genotypes are missing

Boyles, A. L., Scott, W. K., Martin, E. R., Schmidt, S., Li, Y. J., Ashley-Koch, A., Bass, M. P., Schmidt, M., Pericak-Vance, M. A., Speer, M. C. & Hauser, E. R., Aug 1 2005, In : Human Heredity. 59, 4, p. 220-227 8 p.

Research output: Contribution to journal › Article

Linkage Disequilibrium

Genotype

Economic Inflation

Gene Frequency

Haplotypes

5 Citations (Scopus)

Searching for epistatic interactions in nuclear families using conditional linkage analysis

Shah, S. H., Schmidt, M., Mei, H., Scott, W. K., Hauser, E. R. & Schmidt, S., Dec 30 2005, In : BMC Genetics. 6, SUPPL.1, S148.

Research output: Contribution to journal › Article

Nuclear Family

Chromosomes

Single Nucleotide Polymorphism

Siblings

Education