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Mathias G Lichtenheld

Associate Professor

  • 2696 Citations
1988 …2018
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  • 2 Similar Profiles
Perforin Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
tipifarnib Medicine & Life Sciences
Interleukin-2 Medicine & Life Sciences
Complement C9 Medicine & Life Sciences
Natural Killer Cells Medicine & Life Sciences
Cytotoxic T-Lymphocytes Medicine & Life Sciences
Granzymes Medicine & Life Sciences

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Projects 1992 2004

MOLECULAR CHARACTERIZATION OF PERFORIN GENE REGULATION

Lichtenheld, M. G.

National Institutes of Health

9/1/92 → 3/31/04

Project: Research project

Perforin
Cytotoxic T-Lymphocytes
Genes
Natural Killer Cells
Reporter Genes

Research Output 1988 2018

  • 2696 Citations
  • 40 Article

Perforin-2 breaches the envelope of phagocytosed bacteria allowing antimicrobial effectors access to intracellular targets

Bai, F., McCormack, R. M., Hower, S., Plano, G. V., Lichtenheld, M. G. & Munson, G., Nov 1 2018, In : Journal of Immunology. 201, 9, p. 2710-2720 11 p.

Research output: Contribution to journal › Article

Phagocytosis
Bacteria
Peptide Hydrolases
Salmonella enterica
Phagocytes
16 Citations (Scopus)

Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria

McCormack, R. M., de Armas, L. R., Shiratsuchi, M., Fiorentino, D. G., Olsson, M. L., Lichtenheld, M. G., Morales, A., Lyapichev, K., Gonzalez, L. E., Strbo, N., Sukumar, N., Stojadinovic, O., Plano, G. V., Munson, G., Tomic-Canic, M., Kirsner, R., Russell, D. G. & Podack, E. R., Sep 24 2015, In : eLife. 4, September2015, e06508.

Research output: Contribution to journal › Article

Phagocytes
Bacteria
perforin 2
Reactive Nitrogen Species
Salmonella
51 Citations (Scopus)

HIV Nef, Paxillin, and Pak1/2 Regulate Activation and Secretion of TACE/ADAM10 Proteases

Lee, J. H., Wittki, S., Bräu, T., Dreyer, F. S., Krätzel, K., Dindorf, J., Johnston, I. C. D., Gross, S., Kremmer, E., Zeidler, R., Schlötzer-Schrehardt, U., Lichtenheld, M. G., Saksela, K., Harrer, T., Schuler, G., Federico, M. & Baur, A. S., Feb 21 2013, In : Molecular Cell. 49, 4, p. 668-679 12 p.

Research output: Contribution to journal › Article

Paxillin
Peptide Hydrolases
HIV
Integrins
Human Immunodeficiency Virus nef Gene Products
4 Citations (Scopus)

Understanding the biology of ex vivo-expanded CD8 T cells for adoptive cell therapy: Role of CD62L

Díaz-Montero, C. M., Zidan, A. A., Pallin, M. F., Anagnostopoulos, V., Salem, M. L., Wieder, E., Komanduri, K. V., Montero, A. J. & Lichtenheld, M. G., Dec 1 2013, In : Immunologic Research. 57, 1-3, p. 23-33 11 p.

Research output: Contribution to journal › Article

Cell- and Tissue-Based Therapy
T-Lymphocytes
Neoplasms
Lymph Nodes
Animal Structures
30 Citations (Scopus)

Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells

Parmigiani, A., Pallin, M. F., Schmidtmayerova, H., Lichtenheld, M. G. & Pahwa, S. G., Feb 1 2011, In : Human Immunology. 72, 2, p. 115-123 9 p.

Research output: Contribution to journal › Article

Human Activities
Antiviral Agents
Cytokines
T-Lymphocytes
Interleukin-21 Receptors