Lina Shehadeh

Asst. Professor

  • 884 Citations
20022022
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Projects 2006 2022

The Role of Osteopontin-OGDHL Axis in HFpEF

Shehadeh, L.

National Institutes of Health

2/1/181/31/22

Project: Research projectResearch Project

Ketoglutarate Dehydrogenase Complex
Osteopontin
Heart Failure
Phenotype
Renal Hypertension

Osteopontin Signals between Myocytes and Fibroblasts to Regulate Cardiac Remodeling

Shehadeh, L.

National Institutes of Health

9/15/168/31/18

Project: Research projectHigh Priority, Short Term Project Award

Osteopontin
Muscle Cells
Fibroblasts
Heart Failure
Ventricular Remodeling

Mechanisms for miR-30e Regulated Atherogenic Pathways with Age

Shehadeh, L.

National Institutes of Health

9/30/128/31/15

Project: Research projectResearch Scientist Development Award - Research & Training

Mentors
Research
Mesenchymal Stromal Cells
Blood Vessels
Hares

Transcription Factor Networks in Cardiac Hypertrophy

Shehadeh, L.

National Institutes of Health

4/8/064/7/09

Project: Research projectPostdoctoral Individual National Research Service Award

Cardiomegaly
Transcription Factors
Hypertrophy
Genes
Gene Regulatory Networks

Research Output 2002 2018

Isolation, characterization, and high throughput extracellular flux analysis of mouse primary renal tubular epithelial cells

Ding, W., Yousefi, K. & Shehadeh, L., Jun 20 2018, In : Journal of Visualized Experiments. 2018, 136, e57718.

Research output: Contribution to journalArticle

Epithelial Cells
Throughput
Fluxes
Kidney
Purification

Differential expression of microRNAs among cell populations in the regenerating adult mouse olfactory epithelium

Kurtenbach, S., Ding, W., Goss, G. M., Hare, J., Goldstein, B. J. & Shehadeh, L., Nov 1 2017, In : PLoS One. 12, 11, e0187576.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-kit
MicroRNAs
Animals
Cells
Cell culture

New incriminating evidence against IGF2

Ding, W. & Shehadeh, L., Aug 1 2017, In : Translational Cancer Research. 6, p. S949-S952

Research output: Contribution to journalEditorial

3 Citations

Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure

Li, J., Yousefi, K., Ding, W., Singh, J. & Shehadeh, L., May 1 2017, In : Cardiovascular Research. 113, 6, p. 633-643 11 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Osteopontin
Heart Failure
Pressure
Fibrosis
141 Citations

Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy

Grabner, A., Amaral, A. P., Schramm, K., Singh, S., Sloan, A., Yanucil, C., Li, J., Shehadeh, L., Hare, J., David, V., Martin, A., Fornoni, A., Di Marco, G. S., Kentrup, D., Reuter, S., Mayer, A. B., Pavenstädt, H., Stypmann, J., Kuhn, C., Hille, S. & 11 othersFrey, N., Leifheit-Nestler, M., Richter, B., Haffner, D., Abraham, R., Bange, J., Sperl, B., Ullrich, A., Brand, M., Wolf, M. & Faul, C. H., Jan 23 2015, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 4
Left Ventricular Hypertrophy
Chronic Renal Insufficiency
Calcineurin
Cardiomegaly