Konstantinos D. Sarantopoulos

Professor of Clinical

  • 2353 Citations
1991 …2020

Research output per year

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Research Output

2020

Individuals with migraine have a different dry eye symptom profile than individuals without migraine

Farhangi, M., Diel, R. J., Buse, D. C., Huang, A. M., Levitt, R. C., Sarantopoulos, C. D., Felix, E. R. & Galor, A., Feb 1 2020, In : British Journal of Ophthalmology. 104, 2, p. 260-264 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Oral Gabapentinoids and Nerve Blocks for the Treatment of Chronic Ocular Pain

Small, L. R., Galor, A., Felix, E. R., Horn, D. B., Levitt, R. C. & Sarantopoulos, C. D., May 1 2020, In : Eye & contact lens. 46, 3, p. 174-181 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Transcutaneous Electrical Nerve Stimulation for the Long-Term Treatment of Ocular Pain

Zayan, K., Aggarwal, S., Felix, E., Levitt, R., Sarantopoulos, K. & Galor, A., Jan 1 2020, (Accepted/In press) In : Neuromodulation.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Effect of non-invasive intranasal neurostimulation on tear volume, dryness and ocular pain

Farhangi, M., Cheng, A. M., Baksh, B., Sarantopoulos, C. D., Felix, E. R., Levitt, R. C. & Galor, A., Jan 1 2019, (Accepted/In press) In : British Journal of Ophthalmology. 315065.

Research output: Contribution to journalArticle

1 Scopus citations

Modification of the Neuropathic Pain Symptom Inventory for use in eye pain (NPSI-Eye)

Farhangi, M., Feuer, W. J., Galor, A., Bouhassira, D., Levitt, R. C., Sarantopoulos, C. D. & Felix, E. R., Jul 1 2019, In : Pain. 160, 7, p. 1541-1550 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL

Upadhyay, U., Zhuang, G. Z., Diatchenko, L., Parisien, M., Kang, Y., Sarantopoulos, K. D., Martin, E. R., Smithid, S. B., Maixner, W. & Levitt, R. C., Jun 2019, In : PLoS genetics. 15, 6, e1008226.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access
4 Scopus citations
2018

Botulinum Toxin A for the Treatment of Photophobia and Dry Eye

Diel, R. J., Kroeger, Z. A., Levitt, R. C., Sarantopoulos, K. D., Sered, H., Martinez-Barrizonte, J. & Galor, A., Jan 1 2018, In : Ophthalmology. 125, 1, p. 139-140 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Epidemiology of discordance between symptoms and signs of dry eye

Ong, E. S., Felix, E. R., Levitt, R. C., Feuer, W. J., Sarantopoulos, C. D. & Galor, A., May 1 2018, In : British Journal of Ophthalmology. 102, 5, p. 674-679 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Epidemiology of Persistent Dry Eye-Like Symptoms After Cataract Surgery

Iglesias, E., Sajnani, R., Levitt, R. C., Sarantopoulos, K. D. & Galor, A., Jul 1 2018, In : Cornea. 37, 7, p. 893-898 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Epidemiology of Persistent Postsurgical Pain Manifesting as Dry Eye-Like Symptoms after Cataract Surgery

Sajnani, R., Raia, S., Gibbons, A., Chang, V., Karp, C. L., Sarantopoulos, C. D., Levitt, R. C. & Galor, A., Jan 1 2018, In : Cornea. 37, 12, p. 1535-1541 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice

Zhuang, G. Z., Upadhyay, U., Tong, X., Kang, Y., Erasso, D. M., Fu, E., Sarantopoulos, K. D., Martin, E. R., Wiltshire, T., Diatchenko, L., Smith, S. B., Maixner, W. & Levitt, R. C., Apr 24 2018, (Accepted/In press) In : Gene Therapy. p. 1-15 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Neuropathic-Like Ocular Pain and Nonocular Comorbidities Correlate With Dry Eye Symptoms

Chang, V. S., Rose, T. P., Karp, C. L., Levitt, R. C., Sarantopoulos, C. & Galor, A., Nov 1 2018, In : Eye & contact lens. 44, p. S307-S313

Research output: Contribution to journalArticle

1 Scopus citations

Neuropathic pain and dry eye

Galor, A., Moein, H. R., Lee, C., Rodriguez, A., Felix, E., Sarantopoulos, K. D. & Levitt, R. C., Jan 1 2018, In : Ocular Surface. 16, 1, p. 31-44 14 p.

Research output: Contribution to journalReview article

29 Scopus citations

Noninvasive Electrical Stimulation for the Treatment of Chronic Ocular Pain and Photophobia

Sivanesan, E., Levitt, R. C., Sarantopoulos, K. D., Patin, D. & Galor, A., Jan 1 2018, (Accepted/In press) In : Neuromodulation.

Research output: Contribution to journalArticle

9 Scopus citations

Photophobia and sensations of dryness in patients with migraine occur independent of baseline tear volume and improve following botulinum toxin A injections

Diel, R. J., Hwang, J., Kroeger, Z. A., Levitt, R. C., Sarantopoulos, C. D., Sered, H., Felix, E. R., Martinez-Barrizonte, J. & Galor, A., Jan 1 2018, (Accepted/In press) In : British Journal of Ophthalmology.

Research output: Contribution to journalArticle

6 Scopus citations

The Association of Dry Eye Symptom Severity and Comorbid Insomnia in US Veterans

Galor, A., Seiden, B. E., Park, J. J., Feuer, W. J., McClellan, A. L., Felix, E. R., Levitt, R. C., Sarantopoulos, C. D. & Wallace, D. M., Sep 1 2018, In : Eye & contact lens. 44, p. S118-S124

Research output: Contribution to journalArticle

12 Scopus citations

Traumatic brain injury, dry eye and comorbid pain diagnoses in US veterans

Lee, C. J., Felix, E. R., Levitt, R. C., Eddy, C., Vanner, E. A., Feuer, W. J., Sarantopoulos, C. D. & Galor, A., May 1 2018, In : British Journal of Ophthalmology. 102, 5, p. 667-673 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Bulbar conjunctival microvascular responses in dry eye

Chen, W., Batawi, H. I. M., Alava, J. R., Galor, A., Yuan, J., Sarantopoulos, K. D., McClellan, A. L., Feuer, W. J., Levitt, R. C. & Wang, J., Apr 1 2017, In : Ocular Surface. 15, 2, p. 193-201 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice

Levitt, R. C., Zhuang, G. Y., Kang, Y., Erasso, D. M., Upadhyay, U., Ozdemir, M., Fu, E., Sarantopoulos, K. D., Smith, S. B., Maixner, W., Diatchenko, L., Martin, E. R. & Wiltshire, T., May 25 2017, (Accepted/In press) In : Mammalian Genome. p. 1-9 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
24 Scopus citations

Evidence that dry eye is a comorbid pain condition in a U.S. veteran population

Lee, C. J., Levitt, R. C., Felix, E. R., Sarantopoulos, C. D. & Galor, A., Nov 1 2017, In : Pain Reports. 2, 6, e629.

Research output: Contribution to journalArticle

5 Scopus citations

Evidence that dry eye represents a chronic overlapping pain condition

Levitt, A. E., Galor, A., Chowdhury, A. R., Felix, E. R., Sarantopoulos, C. D., Zhuang, G. Y., Patin, D., Maixner, W., Smith, S. B., Martin, E. R. & Levitt, R. C., Sep 1 2017, In : Molecular Pain. 13

Research output: Contribution to journalReview article

9 Scopus citations

Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice

Fu, E. S., Erasso, D. M., Zhuang, G. Z., Upadhyay, U., Ozdemir, M., Wiltshire, T., Sarantopoulos, K. D., Smith, S. B., Maixner, W., Martin, E. R. & Levitt, R. C., Jan 1 2017, In : Neuroreport. 28, 18, p. 1215-1220 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Longitudinal examination of frequency of and risk factors for severe dry eye symptoms in us veterans

Ong, E. S., Alghamdi, Y. A., Levitt, R. C., McClellan, A. L., Lewis, G., Sarantopoulos, C. D., Felix, E. R. & Galor, A., Feb 1 2017, In : JAMA ophthalmology. 135, 2, p. 116-123 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
5 Scopus citations
2016

Assessment of somatosensory function in patients with idiopathic dry eye symptoms

Galor, A., Levitt, R. C., McManus, K. T., Kalangara, J. P., Seiden, B. E., Park, J. J., Covington, D. B., Sarantopoulos, K. D. & Felix, E., Nov 1 2016, In : JAMA Ophthalmology. 134, 11, p. 1290-1298 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Burning Eye Syndrome: Do Neuropathic Pain Mechanisms Underlie Chronic Dry Eye?

Kalangara, J. P., Galor, A., Levitt, R. C., Felix, E., Alegret, R. & Sarantopoulos, K. D., Apr 1 2016, In : Pain medicine (Malden, Mass.). 17, 4, p. 746-755 10 p.

Research output: Contribution to journalReview article

15 Scopus citations

Characteristics of Ocular Pain Complaints in Patients With Idiopathic Dry Eye Symptoms

Kalangara, J. P., Galor, A., Levitt, R. C., Covington, D. B., McManus, K. T., Sarantopoulos, K. D. & Felix, E., Feb 29 2016, (Accepted/In press) In : Eye and Contact Lens.

Research output: Contribution to journalArticle

27 Scopus citations

Corneal mechanical thresholds negatively associate with dry eye and ocular pain symptoms

Spierer, O., Felix, E. R., McClellan, A. L., Parel, J. M., Gonzalez, A., Feuer, W. J., Sarantopoulos, C. D., Levitt, R. C., Ehrmann, K. & Galor, A., Feb 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 2, p. 617-625 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Dry Eye Profiles in Patients with a Positive Elevated Surface Matrix Metalloproteinase 9 Point-of-Care Test Versus Negative Patients

Lanza, N. L., McClellan, A. L., Batawi, H., Felix, E., Sarantopoulos, K. D., Levitt, R. C. & Galor, A., Apr 1 2016, In : Ocular Surface. 14, 2, p. 216-223 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
25 Scopus citations

What can photophobia tell us about dry eye?

Galor, A., Levitt, R. C., Felix, E. R. & Sarantopoulos, C. D., Aug 25 2016, In : Expert Review of Ophthalmology. 11, 5, p. 321-324 4 p.

Research output: Contribution to journalEditorial

3 Scopus citations

ω-3 tear film lipids correlate with clinical measures of dry eye

Walter, S. D., Gronert, K., McClellan, A. L., Levitt, R. C., Sarantopoulos, K. D. & Galor, A., May 2016, In : Investigative Ophthalmology and Visual Science. 57, 6, p. 2472-2478 7 p.

Research output: Contribution to journalArticle

34 Scopus citations
2015

Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway

Zhuang, G. Z., Keeler, B., Grant, J., Bianchi, L., Fu, E. S., Zhang, Y. P., Erasso, D. M., Cui, J. G., Wiltshire, T., Li, Q., Hao, S., Sarantopoulos, K. D., Candiotti, K., Wishnek, S. M., Smith, S. B., Maixner, W., Diatchenko, L., Martin, E. R. & Levitt, R. C., Mar 3 2015, In : PloS one. 10, 3, e0118273.

Research output: Contribution to journalArticle

15 Scopus citations
51 Scopus citations

Dry eye symptoms align more closely to non-ocular conditions than to tear film parameters

Galor, A., Felix, E. R., Feuer, W. J., Shalabi, N., Martin, E. R., Margolis, T. P., Sarantopoulos, C. D. & Levitt, R. C., Aug 1 2015, In : British Journal of Ophthalmology. 99, 8, p. 1126-1129 4 p.

Research output: Contribution to journalArticle

44 Scopus citations

Dry eye symptom severity and persistence are associated with symptoms of neuropathic pain

Galor, A., Zlotcavitch, L., Walter, S. D., Felix, E. R., Feuer, W. J., Martin, E. R., Margolis, T. P., Sarantopoulos, K. D. & Levitt, R. C., May 1 2015, In : British Journal of Ophthalmology. 99, 5, p. 665-668 4 p.

Research output: Contribution to journalArticle

43 Scopus citations

Human Tear Serotonin Levels Correlate with Symptoms and Signs of Dry Eye

Chhadva, P., Lee, T., Sarantopoulos, C. D., Hackam, A. S., McClellan, A. L., Felix, E. R., Levitt, R. C. & Galor, A., Aug 1 2015, In : Ophthalmology. 122, 8, p. 1675-1680 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Incomplete response to artificial tears is associated with features of neuropathic ocular pain

Galor, A., Batawi, H., Felix, E., Margolis, T. P., Sarantopoulos, K. D., Martin, E. R. & Levitt, R. C., Sep 16 2015, (Accepted/In press) In : British Journal of Ophthalmology.

Research output: Contribution to journalArticle

32 Scopus citations

Neuropathic ocular pain: An important yet underevaluated feature of dry eye

Galor, A., Levitt, R. C., Felix, E., Martin, E. R. & Sarantopoulos, K. D., Mar 15 2015, In : Eye (Basingstoke). 29, 3, p. 301-312 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

Neuropathic Ocular Pain due to Dry Eye Is Associated With Multiple Comorbid Chronic Pain Syndromes

Galor, A., Covington, D., Levitt, A. E., McManus, K. T., Seiden, B., Felix, E. R., Kalangara, J., Feuer, W. J., Patin, D. J., Martin, E. R., Sarantopoulos, K. D. & Levitt, R. C., Aug 10 2015, (Accepted/In press) In : Journal of Pain.

Research output: Contribution to journalArticle

38 Scopus citations

Understanding the true burden of dry eye disease

Galor, A., Levitt, R. C., Felix, E. & Sarantopoulos, K. D., Sep 3 2015, In : Expert Review of Ophthalmology. 10, 5, p. 403-405 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2013
4 Scopus citations
2012

Transdermal buprenorphine controls central neuropathic pain

Weiner, M., Sarantopoulos, C. & Gordon, E., Nov 1 2012, In : Journal of Opioid Management. 8, 6, p. 414-415 2 p.

Research output: Contribution to journalArticle

11 Scopus citations
2010

KATP channel subunits in rat dorsal root ganglia: Alterations by painful axotomy

Zoga, V., Kawano, T., Liang, M. Y., Bienengraeber, M., Weihrauch, D., McCallum, B., Gemes, G., Hogan, Q. & Sarantopoulos, C., Jan 26 2010, In : Molecular Pain. 6, 6.

Research output: Contribution to journalArticle

42 Scopus citations
2009

ATP-sensitive potassium currents in rat primary afferent neurons: biophysical, pharmacological properties, and alterations by painful nerve injury

Kawano, T., Zoga, V., McCallum, J. B., Wu, H. E., Gemes, G., Liang, M. Y., Abram, S., Kwok, W. M., Hogan, Q. H. & Sarantopoulos, C. D., Aug 18 2009, In : Neuroscience. 162, 2, p. 431-443 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

Channels of preconditioning: Potassium drain that protects the brain

Bosnjak, Z. J. & Sarantopoulos, C. D., May 2009, In : Anesthesiology. 110, 5, p. 961-963 3 p.

Research output: Contribution to journalEditorial

2 Scopus citations