Karoline Briegel

Research Associate Professor

  • 728 Citations
1991 …2020

Research output per year

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Research Output

  • 728 Citations
  • 22 Article
  • 2 Review article
  • 1 Comment/debate
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Article
2019

Loss of Limb-Bud-and-Heart (LBH) attenuates mammary hyperplasia and tumor development in MMTV-Wnt1 transgenic mice

Ashad-Bishop, K., Garikapati, K., Lindley, L. E., Jorda, M. & Briegel, K., Jan 8 2019, In : Biochemical and Biophysical Research Communications. 508, 2, p. 536-542 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

MicroRNA let-7 downregulates ligand-independent estrogen receptor–mediated male-predominant pulmonary fibrosis

Elliot, S., Periera-Simon, S., Xia, X., Catanuto, P., Rubio, G., Shahzeidi, S., El Salem, F., Shapiro, J., Briegel, K., Korach, K. S. & Glassberg, M. K., Nov 15 2019, In : American journal of respiratory and critical care medicine. 200, 10, p. 1246-1257 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

P27 transcriptionally coregulates cJun to drive programs of tumor progression

Yoon, H., Kim, M., Jang, K., Shin, M., Besser, A., Xiao, X., Zhao, D., Wander, S. A., Briegel, K., Morey, L., Minn, A. & Slingerland, J. M., Apr 2 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7005-7014 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2017

Regulation of the cell cycle and inflammatory arthritis by the transcription cofactor LBH gene

Matsuda, S., Hammaker, D., Topolewski, K., Briegel, K. J., Boyle, D. L., Dowdy, S., Wang, W. & Firestein, G. S., Oct 1 2017, In : Journal of Immunology. 199, 7, p. 2316-2322 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage

Lindley, L. E., Curtis, K. M., Sanchez-Mejias, A., Rieger, M. E., Robbins, D. J. & Briegel, K., 2015, In : Development (Cambridge). 142, 5, p. 893-904 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
2013

Generation of mice with a conditional Lbh null allele

Lindley, L. E. & Briegel, K. J., Jul 1 2013, In : Genesis. 51, 7, p. 491-497 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012

Hedgehog signaling regulates bladder cancer growth and tumorigenicity

Fei, D. L., Sanchez-Mejias, A., Wang, Z., Flaveny, C., Long, J., Singh, S., Rodriguez-Blanco, J., Tokhunts, R., Giambelli, C., Briegel, K. J., Schulz, W. A., Gandolfi, A. J., Karagas, M., Zimmers, T. A., Jorda, M., Bejarano, P., Capobianco, A. J. & Robbins, D. J., Sep 1 2012, In : Cancer Research. 72, 17, p. 4449-4458 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

The T box transcription factor TBX2 promotes epithelial-mesenchymal transition and invasion of normal and malignant breast epithelial cells

Wang, B., Lindley, L. E., Fernandez-Vega, V., Rieger, M. E., Sims, A. H. & Briegel, K. J., Jul 23 2012, In : PloS one. 7, 7, e41355.

Research output: Contribution to journalArticle

41 Scopus citations
2011

Hedgehog-producing cancer cells respond to and require autocrine hedgehog activity

Singh, S., Wang, Z., Fei, D. L., Black, K. E., Goetz, J. A., Tokhunts, R., Giambelli, C., Rodriguez-Blanco, J., Long, J., Lee, E., Briegel, K. J., Bejarano, P. A., Dmitrovsky, E., Capobianco, A. J. & Robbins, D. J., Jul 1 2011, In : Cancer Research. 71, 13, p. 4454-4463 10 p.

Research output: Contribution to journalArticle

32 Scopus citations
2010
18 Scopus citations
49 Scopus citations

The embryonic transcription cofactor LBH is a direct target of the Wnt signaling pathway in epithelial development and in aggressive basal subtype breast cancers

Rieger, M. E., Sims, A. H., Coats, E. R., Clarke, R. B. & Briegel, K. J., Sep 1 2010, In : Molecular and cellular biology. 30, 17, p. 4267-4279 13 p.

Research output: Contribution to journalArticle

50 Scopus citations
2006

Identification and analysis of Escherichia coli ribonuclease E dominant-negative mutants

Briegel, K. J., Baker, A. & Jain, C., Jan 1 2006, In : Genetics. 172, 1, p. 7-15 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
2005

Congenital heart disease reminiscent of partial trisomy 2p syndrome in mice transgenic for the transcription factor Lbh

Briegel, K. J., Baldwin, H. S., Epstein, J. A. & Joyner, A. L., Jul 1 2005, In : Development. 132, 14, p. 3305-3316 12 p.

Research output: Contribution to journalArticle

36 Scopus citations
2001

Identification and characterization of Lbh, a novel conserved nuclear protein expressed during early limb and heart development

Briegel, K. J. & Joyner, A. L., May 15 2001, In : Developmental Biology. 233, 2, p. 291-304 14 p.

Research output: Contribution to journalArticle

49 Scopus citations

Molecular cloning, expression and regulation of the avian tubby-like protein 1 (tulp1) gene

Heikenwälder, M. F., Koritschoner, N. P., Pajer, P., Chaboissier, M. C., Kurz, S. M., Briegel, K. J., Bartunek, P. & Zenke, M., Jul 25 2001, In : Gene. 273, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
2000

Dendritic cells conditionally transformed by v-relER oncogene express lymphoid marker genes

Madruga, J., Briegel, K., Diebold, S., Boehmelt, G., Vogel, F. & Zenke, M., Jan 1 2000, In : Immunobiology. 202, 4, p. 394-407 14 p.

Research output: Contribution to journalArticle

2 Scopus citations
1996

Regulation and function of transcription factor GATA-1 during red blood cell differentiation

Briegel, K., Bartunek, P., Stengl, G., Lim, K. C., Beug, H., Engel, J. D. & Zenke, M., Dec 1 1996, In : Development. 122, 12, p. 3839-3850 12 p.

Research output: Contribution to journalArticle

42 Scopus citations
1995

Dendritic cell progenitor is transformed by a conditional v-Rel estrogen receptor fusion protein v-ReIER

Boehmelt, G., Madruga, J., Ddrfler, P., Briegel, K., Schwarz, H., Enrietto, P. J. & Zenke, M., Jan 27 1995, In : Cell. 80, 2, p. 341-352 12 p.

Research output: Contribution to journalArticle

57 Scopus citations
1993

Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner

Briegel, K., Lim, K. C., Plank, C., Beug, H., Engel, J. D. & Zenke, M., Jun 1993, In : Genes and Development. 7, 6, p. 1097-1109 13 p.

Research output: Contribution to journalArticle

Open Access
163 Scopus citations
1992

cis and trans regulation of tissue-specific transcription

Engel, J. D., Beug, H., LaVail, J. H., Zenke, M. W., Mayo, K., Leonard, M. W., Foley, K. P., Yang, Z., Kornhauser, J. M., Ko, L. J., Lim, K. C., George, K. M. & Breigel, K., Dec 1 1992, In : Journal of Cell Science. 103, SUPPL. 16, p. 21-31 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
1991

One base pair change abolishes the T cell-restricted activity of a kB-like proto-enhancer element from the interleukin 2 promoter

Briegel, K., Hentsch, B., Pfeuffer, I. & Serfling, E., Nov 11 1991, In : Nucleic acids research. 19, 21, p. 5929-5936 8 p.

Research output: Contribution to journalArticle

45 Scopus citations