Karina Galoian

Research Associate Professor

  • 322 Citations
19962019
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Research Output 1996 2019

  • 322 Citations
  • 21 Article
  • 2 Review article
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Article
2019

PRP-1 significantly decreases the ALDHhigh cancer stem cell population and regulates the aberrant Wnt/β-catenin pathway in human chondrosarcoma JJ012 cells

Hoyt, A. K., Moran, A., Granger, C., Sedani, A., Saigh, S., Brown, J. & Galoian, K., Jul 1 2019, In : Oncology Reports. 42, 1, p. 103-114 12 p.

Research output: Contribution to journalArticle

Open Access
PRP-1 peptide
Catenins
Chondrosarcoma
Wnt Signaling Pathway
Neoplastic Stem Cells
2018

Analysis of IL6-protein complexes in chondrosarcoma

Galoian, K., Luo, S. & Patel, P., Jan 1 2018, In : Biomedical Reports. 8, 1, p. 91-98 8 p.

Research output: Contribution to journalArticle

Chondrosarcoma
Interleukin-6
Ubiquitination
Proteins
Down-Regulation
3 Citations (Scopus)

Toll like receptors TLR1/2, TLR6 and MUC5B as binding interaction partners with cytostatic proline rich polypeptide 1 in human chondrosarcoma

Galoian, K., Abrahamyan, S., Chailyan, G., Qureshi, A., Patel, P. H., Metser, G., Moran, A., Sahakyan, I., Tumasyan, N., Lee, A., Davtyan, T., Chailyan, S. & Galoyan, A., Jan 1 2018, In : International Journal of Oncology. 52, 1, p. 139-154 16 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Toll-Like Receptor 2
Chondrosarcoma
Cytostatic Agents
Neoplasms
2015
6 Citations (Scopus)

Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1

Galoian, K., Qureshi, A., D'Ippolito, G., Schiller, P. C., Molinari, M., Johnstone, A. L., Brothers, S. P., Paz, A. C. & Thomas Temple, H., Aug 1 2015, In : International Journal of Oncology. 47, 2, p. 465-472 8 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Chondrosarcoma
Embryonic Stem Cells
Epigenomics
MicroRNAs
49 Citations (Scopus)

Treatment with a small molecule mutant IDH1 inhibitor suppresses tumorigenic activity and decreases production of the oncometabolite 2-hydroxyglutarate in human chondrosarcoma cells

Li, L., Paz, A. C., Wilky, B. A., Johnson, B., Galoian, K., Rosenberg, A., Hu, G., Tinoco, G., Bodamer, O. & Trent, J., Sep 14 2015, In : PLoS One. 10, 9, e0133813.

Research output: Contribution to journalArticle

Chondrosarcoma
mutation
mutants
Molecules
Mutation
2014
2 Citations (Scopus)

Genome-wide mRNA and miRNA expression data analysis to screen for markers involved in sarcomagenesis in human chondrosarcoma cell lines

Issac, B., Galoian, K., Guettouche, T., Navarro, L. & Thomas Temple, H., Jan 1 2014, In : Genomics Data. 2, p. 320-324 5 p.

Research output: Contribution to journalArticle

Chondrosarcoma
MicroRNAs
Genes
Cells
Genome
4 Citations (Scopus)

Lost miRNA surveillance of Notch, IGFR pathway-road to sarcomagenesis

Galoian, K., Guettouche, T., Issac, B., Navarro, L. & Thomas Temple, H., Jan 1 2014, In : Tumor Biology. 35, 1, p. 483-492 10 p.

Research output: Contribution to journalArticle

Somatomedin Receptors
MicroRNAs
Testicular Neoplasms
Chondrosarcoma
Genes
14 Citations (Scopus)

Regulation of onco and tumor suppressor MiRNAs by mTORC1 inhibitor PRP-1 in human chondrosarcoma

Galoian, K., Guettouche, T., Issac, B., Qureshi, A. & Thomas Temple, H., Jan 1 2014, In : Tumor Biology. 35, 3, p. 2335-2341 7 p.

Research output: Contribution to journalArticle

Chondrosarcoma
MicroRNAs
PRP-1 peptide
Neoplasms
Mesenchymal Chondrosarcoma
2012
21 Citations (Scopus)

mTORC1 inhibition and ECM-cell adhesion-independent drug resistance via PI3K-AKT and PI3K-RAS-MAPK feedback loops

Galoian, K., Thomas Temple, H. & Galoyan, A., Jun 1 2012, In : Tumor Biology. 33, 3, p. 885-890 6 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Sirolimus
Mitogen-Activated Protein Kinases
Phosphatidylinositol 3-Kinases
Drug Resistance
2 Citations (Scopus)

The protective and immunomodulatory effects of hypothalamic proline-rich polypeptide galarmin against methicillin-resistant Staphylococcus aureus infection in mice

Durgaryan, A. A., Matevosyan, M. B., Seferyan, Y., Sargsyan, M. A., Grigoryan, S. L., Galoyan, A. A. & Galoian, K., Sep 1 2012, In : European Journal of Clinical Microbiology and Infectious Diseases. 31, 9, p. 2153-2165 13 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Methicillin-Resistant Staphylococcus aureus
Proline
Peptides
Infection
2011
7 Citations (Scopus)

Cytostatic effect of novel mTOR inhibitor, PRP-1 (galarmin) in MDA 231 (ER?) breast carcinoma cell line. PRP-1 inhibits mesenchymal tumors

Galoian, K., Thomas Temple, H. & Galoyan, A., Aug 1 2011, In : Tumor Biology. 32, 4, p. 745-751 7 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Cytostatic Agents
Breast Neoplasms
Cell Line
Neoplasms
11 Citations (Scopus)

Cytostatic effect of the hypothalamic cytokine prp-1 is mediated by mTOR and cMYc inhibition in high grade chondrosarcoma

Galoian, K., Thomas Temple, H. & Galoyan, A., May 1 2011, In : Neurochemical Research. 36, 5, p. 812-818 7 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Chondrosarcoma
Cytostatic Agents
Sirolimus
Cytokines
2 Citations (Scopus)

Proline rich polypeptide (prp-1) increases the superoxide-producing and ferrihemoglobin reducing activities of cytochrome b558 isoforms from human lymphosarcoma tissue cells

Simonyan, G. M., Galoian, K., Simonyan, R. M., Simonyan, M. A. & Galoyan, A. A., May 1 2011, In : Neurochemical Research. 36, 5, p. 739-745 7 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Methemoglobin
Proline
Superoxides
Non-Hodgkin's Lymphoma
2010
10 Citations (Scopus)

Antioxidant and electron donating function of hypothalamic polypeptides: Galarmin and Gx-NH2

Tavadyan, L. A., Galoian, K., Harutunyan, L. A., Tonikyan, H. G. & Galoyan, A. A., Jun 1 2010, In : Neurochemical Research. 35, 6, p. 947-952 6 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Antioxidants
Electrons
Peptides
Voltammetry
8 Citations (Scopus)

Utility of quantitative computerized pain drawings in a sample of spinal stenosis patients

Felix, E., Galoian, K., Aarons, C., Brown, M., Kearing, S. A. & Heiss, U., Mar 1 2010, In : Pain Medicine. 11, 3, p. 382-389 8 p.

Research output: Contribution to journalArticle

Spinal Stenosis
Pain
Hypesthesia
2009
8 Citations (Scopus)

Antitumorigenic effect of brain proline rich polypeptide-1 in human chondrosarcoma

Galoian, K., Scully, S., McNamara, G., Flynn, P. & Galoyan, A., Dec 1 2009, In : Neurochemical Research. 34, 12, p. 2117-2121 5 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Neurophysins
Chondrosarcoma
Cartilage
Neuropeptides
12 Citations (Scopus)

Myc-oncogene inactivating effect by Proline Rich Polypeptide (PRP-1) in chondrosarcoma JJ012 cells

Galoian, K., Scully, S. & Galoyan, A., Feb 1 2009, In : Neurochemical Research. 34, 2, p. 379-385 7 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Chondrosarcoma
myc Genes
Proline
Bone
2007
5 Citations (Scopus)

Effect of hypothalamic proline-rich peptide (PRP-1) on neuronal and bone marrow cell apoptosis

Galoyan, A. A., Krieglstein, J., Klumpp, S., Danielian, K. E., Galoian, K., Kremers, W., Bezirganyan, K. B. & Davtyan, T. K., Nov 1 2007, In : Neurochemical Research. 32, 11, p. 1898-1905 8 p.

Research output: Contribution to journalArticle

PRP-1 peptide
Proline
Bone Marrow Cells
Bone
Staurosporine
12 Citations (Scopus)

Molecular mechanism of tenascin-C action on matrix metalloproteinase-1 invasive potential

Galoian, K., Garamszegi, N., Garamszegi, S. P. & Scully, S. P., Apr 1 2007, In : Experimental Biology and Medicine. 232, 4, p. 515-522 8 p.

Research output: Contribution to journalArticle

Tenascin
Matrix Metalloproteinase 1
Chemical activation
Cultured Cells
Bovine Serum Albumin
2003
123 Citations (Scopus)

Dimerization of MLL fusion proteins immortalizes hematopoietic cells

Martin, M. E., Milne, T. A., Bloyer, S., Galoian, K., Shen, W., Gibbs, D., Brock, H. W., Slany, R. & Hess, J. L., Sep 1 2003, In : Cancer Cell. 4, 3, p. 197-207 11 p.

Research output: Contribution to journalArticle

Dimerization
Exons
Up-Regulation
CpG Islands
Proteins
1996
13 Citations (Scopus)

Molecular and pharmacological identity of the α2D-adrenergic receptor subtype in bovine retina and its photoreceptors

Venkataraman, V., Duda, T., Galoian, K. & Sharma, R. K., Dec 1 1996, In : Molecular and Cellular Biochemistry. 159, 2, p. 129-138 10 p.

Research output: Contribution to journalArticle

Adrenergic Receptors
Retina
Genes
Pharmacology
Rats