Karina Galoian

Research Associate Professor

  • 355 Citations
19962020

Research output per year

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Research Output

  • 355 Citations
  • 24 Article
  • 2 Review article
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Article
2020

Morpho-functional study of the hypothalamic proline-rich polypeptide apoptotic activity against mouse Ehrlich ascites carcinoma

Abrahamyan, S., Sahakyan, I., Tumasyan, N., Kocharyan, N., Simonyan, A., Aroutiounian, R., Chailyan, G., Chailyan, S., Davtyan, T. & Galoian, K., Jul 2020, In : Oncology Reports. 44, 1, p. 196-212 17 p.

Research output: Contribution to journalArticle

Open Access

Mutant idh1 depletion downregulates integrins and impairs chondrosarcoma growth

Li, L., Hu, X., Eid, J. E., Rosenberg, A. E., Wilky, B. A., Ban, Y., Sun, X., Galoian, K., Desalvo, J., Yue, J., Chen, X. S., Blonska, M. & Trent, J., Jan 2020, In : Cancers. 12, 1, 141.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Proline-rich polypeptide-1 decreases cancer stem cell population by targeting BAFF chromatin-remodeling complexes in human chondrosarcoma JJ012 cells

Moran, A., Hoyt, A., Sedani, A., Granger, C., Saigh, S., Blonska, M., Zhao-Ju, L., Conway, S. A., Pretell, J., Brown, J. & Galoian, K., Jul 2020, In : Oncology Reports. 44, 1, p. 393-403 11 p.

Research output: Contribution to journalArticle

2019

PRP-1 significantly decreases the ALDHhigh cancer stem cell population and regulates the aberrant Wnt/β-catenin pathway in human chondrosarcoma JJ012 cells

Hoyt, A. K., Moran, A., Granger, C., Sedani, A., Saigh, S., Brown, J. & Galoian, K. A., Jul 2019, In : Oncology Reports. 42, 1, p. 103-114 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Analysis of IL6-protein complexes in chondrosarcoma

Galoian, K., Luo, S. & Patel, P., Jan 2018, In : Biomedical Reports. 8, 1, p. 91-98 8 p.

Research output: Contribution to journalArticle

Toll like receptors TLR1/2, TLR6 and MUC5B as binding interaction partners with cytostatic proline rich polypeptide 1 in human chondrosarcoma

Galoian, K., Abrahamyan, S., Chailyan, G., Qureshi, A., Patel, P. H., Metser, G., Moran, A., Sahakyan, I., Tumasyan, N., Lee, A., Davtyan, T., Chailyan, S. & Galoyan, A., Jan 2018, In : International journal of oncology. 52, 1, p. 139-154 16 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1

Galoian, K., Qureshi, A., D'Ippolito, G., Schiller, P. C., Molinari, M., Johnstone, A. L., Brothers, S. P., Paz, A. C. & Temple, H. T., Aug 1 2015, In : International journal of oncology. 47, 2, p. 465-472 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Treatment with a small molecule mutant IDH1 inhibitor suppresses tumorigenic activity and decreases production of the oncometabolite 2-hydroxyglutarate in human chondrosarcoma cells

Li, L., Paz, A. C., Wilky, B. A., Johnson, B., Galoian, K., Rosenberg, A., Hu, G., Tinoco, G., Bodamer, O. & Trent, J. C., Sep 14 2015, In : PloS one. 10, 9, e0133813.

Research output: Contribution to journalArticle

53 Scopus citations
2014

Genome-wide mRNA and miRNA expression data analysis to screen for markers involved in sarcomagenesis in human chondrosarcoma cell lines

Issac, B., Galoian, K., Guettouche, T., Navarro, L. & Temple, H. T., Jan 1 2014, In : Genomics Data. 2, p. 320-324 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Lost miRNA surveillance of Notch, IGFR pathway-road to sarcomagenesis

Galoian, K., Guettouche, T., Issac, B., Navarro, L. & Temple, H. T., Jan 1 2014, In : Tumor Biology. 35, 1, p. 483-492 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Regulation of onco and tumor suppressor MiRNAs by mTORC1 inhibitor PRP-1 in human chondrosarcoma

Galoian, K. A., Guettouche, T., Issac, B., Qureshi, A. & Temple, H. T., Jan 1 2014, In : Tumor Biology. 35, 3, p. 2335-2341 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2012

mTORC1 inhibition and ECM-cell adhesion-independent drug resistance via PI3K-AKT and PI3K-RAS-MAPK feedback loops

Galoian, K., Temple, H. T. & Galoyan, A., Jun 1 2012, In : Tumor Biology. 33, 3, p. 885-890 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

The protective and immunomodulatory effects of hypothalamic proline-rich polypeptide galarmin against methicillin-resistant Staphylococcus aureus infection in mice

Durgaryan, A. A., Matevosyan, M. B., Seferyan, Y., Sargsyan, M. A., Grigoryan, S. L., Galoyan, A. A. & Galoian, K. A., Sep 1 2012, In : European Journal of Clinical Microbiology and Infectious Diseases. 31, 9, p. 2153-2165 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2011

Cytostatic effect of novel mTOR inhibitor, PRP-1 (galarmin) in MDA 231 (ER?) breast carcinoma cell line. PRP-1 inhibits mesenchymal tumors

Galoian, K. A., Temple, T. H. & Galoyan, A., Aug 1 2011, In : Tumor Biology. 32, 4, p. 745-751 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Cytostatic effect of the hypothalamic cytokine prp-1 is mediated by mTOR and cMYc inhibition in high grade chondrosarcoma

Galoian, K., Temple, T. H. & Galoyan, A., May 1 2011, In : Neurochemical Research. 36, 5, p. 812-818 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Proline rich polypeptide (prp-1) increases the superoxide-producing and ferrihemoglobin reducing activities of cytochrome b558 isoforms from human lymphosarcoma tissue cells

Simonyan, G. M., Galoian, K. A., Simonyan, R. M., Simonyan, M. A. & Galoyan, A. A., May 1 2011, In : Neurochemical Research. 36, 5, p. 739-745 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2010

Antioxidant and electron donating function of hypothalamic polypeptides: Galarmin and Gx-NH2

Tavadyan, L. A., Galoian, K. A., Harutunyan, L. A., Tonikyan, H. G. & Galoyan, A. A., Jun 1 2010, In : Neurochemical Research. 35, 6, p. 947-952 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Utility of quantitative computerized pain drawings in a sample of spinal stenosis patients

Felix, E. R., Galoian, K. A., Aarons, C., Brown, M. D., Kearing, S. A. & Heiss, U., Mar 2010, In : Pain Medicine. 11, 3, p. 382-389 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2009

Antitumorigenic effect of brain proline rich polypeptide-1 in human chondrosarcoma

Galoian, K., Scully, S., McNamara, G., Flynn, P. & Galoyan, A., Dec 1 2009, In : Neurochemical Research. 34, 12, p. 2117-2121 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Myc-oncogene inactivating effect by Proline Rich Polypeptide (PRP-1) in chondrosarcoma JJ012 cells

Galoian, K., Scully, S. & Galoyan, A., Feb 1 2009, In : Neurochemical Research. 34, 2, p. 379-385 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2007

Effect of hypothalamic proline-rich peptide (PRP-1) on neuronal and bone marrow cell apoptosis

Galoyan, A. A., Krieglstein, J., Klumpp, S., Danielian, K. E., Galoian, K. A., Kremers, W., Bezirganyan, K. B. & Davtyan, T. K., Nov 1 2007, In : Neurochemical Research. 32, 11, p. 1898-1905 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Molecular mechanism of tenascin-C action on matrix metalloproteinase-1 invasive potential

Galoian, K. A., Garamszegi, N., Garamszegi, S. P. & Scully, S. P., Apr 1 2007, In : Experimental Biology and Medicine. 232, 4, p. 515-522 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2003

Dimerization of MLL fusion proteins immortalizes hematopoietic cells

Martin, M. E., Milne, T. A., Bloyer, S., Galoian, K., Shen, W., Gibbs, D., Brock, H. W., Slany, R. & Hess, J. L., Sep 1 2003, In : Cancer Cell. 4, 3, p. 197-207 11 p.

Research output: Contribution to journalArticle

130 Scopus citations
1996

Molecular and pharmacological identity of the α2D-adrenergic receptor subtype in bovine retina and its photoreceptors

Venkataraman, V., Duda, T., Galoian, K. & Sharma, R. K., Jan 1 1996, In : Molecular and Cellular Biochemistry. 159, 2, p. 129-138 10 p.

Research output: Contribution to journalArticle

13 Scopus citations