Karen Young

Associate Professor of Clinical

  • 368 Citations
20022020

Research output per year

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Research Output

  • 368 Citations
  • 26 Article
  • 1 Chapter
  • 1 Comment/debate
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Article
2020

Effects of Klotho supplementation on hyperoxia-induced renal injury in a rodent model of postnatal nephrogenesis

Ali, M. F., Venkatarayappa, S. K. B., Benny, M., Rojas, C., Yousefi, K., Shehadeh, L. A., Kulandavelu, S., Sharma, M., Da Silva, N., Freundlich, M., Abitbol, C. L., DeFreitas, M. J. & Young, K. C., Jan 1 2020, (Accepted/In press) In : Pediatric Research.

Research output: Contribution to journalArticle

Neonatal hyperoxia exposure induces aortic biomechanical alterations and cardiac dysfunction in juvenile rats

Benny, M., Hernandez, D. R., Sharma, M., Yousefi, K., Kulandavelu, S., Batlahally, S., Zambrano, R., Chen, P., Martinez, E. C., Schmidt, A. F., Shehadeh, L. A., Vasquez-Padron, R. I., Wu, S., Velazquez, O. C. & Young, K. C., Jan 1 2020, In : Physiological Reports. 8, 1, e14334.

Research output: Contribution to journalArticle

Open Access
2019

Caspase-1 Inhibition Attenuates Hyperoxia-induced Lung and Brain Injury in Neonatal Mice

Dapaah-Siakwan, F., Zambrano, R., Luo, S., Duncan, M. R., Kerr, N., Donda, K., De Rivero Vaccari, J. P., Keane, R. W., Dalton Dietrich, W., Benny, M., Young, K. & Wu, S., Jan 1 2019, In : American journal of respiratory cell and molecular biology. 61, 3, p. 341-354 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Intra-tracheal administration of a naked plasmid expressing stromal derived factor-1 improves lung structure in rodents with experimental bronchopulmonary dysplasia

Guerra, K., Bryan, C., Dapaah-Siakwan, F., Sammour, I., Drummond, S., Zambrano, R., Chen, P., Huang, J., Sharma, M., Shrager, S., Benny, M., Wu, S. & Young, K. C., Nov 12 2019, In : Respiratory research. 20, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

TNFα-stimulated protein 6 (TSG-6) reduces lung inflammation in an experimental model of bronchopulmonary dysplasia

Bryan, C., Sammour, I., Guerra, K., Sharma, M., Dapaah-Siakwan, F., Huang, J., Zambrano, R., Benny, M., Wu, S. & Young, K., Feb 1 2019, In : Pediatric Research. 85, 3, p. 390-397 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth

Donda, K., Zambrano, R., Moon, Y., Percival, J., Vaidya, R., Dapaah-Siakwan, F., Luo, S., Duncan, M. R., Bao, Y., Wang, L., Qin, L., Benny, M., Young, K. & Wu, S., Jul 2018, In : PloS one. 13, 7, e0199927.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Inhibition of Rac1 Signaling Downregulates Inflammasome Activation and Attenuates Lung Injury in Neonatal Rats Exposed to Hyperoxia

Hummler, J. K., Dapaah-Siakwan, F., Vaidya, R., Zambrano, R., Luo, S., Chen, S., Kerr, N., de Rivero Vaccari, J. P. P., Keane, R., Dalton Dietrich, W., Bancalari, E., Young, K. & Wu, S., Mar 1 2017, In : Neonatology. 111, 3, p. 280-288 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Intra-amniotic soluble endoglin impairs lung development in neonatal rats

Somashekar, S. T., Sammour, I., Huang, J., Dominguez-Bendala, J., Pastori, R., Alvarez-Cubela, S., Torres, E., Wu, S. & Young, K., Oct 1 2017, In : American Journal of Respiratory Cell and Molecular Biology. 57, 4, p. 468-476 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Recombinant CCN1 prevents hyperoxia-induced lung injury in neonatal rats

Vaidya, R., Zambrano, R., Hummler, J. K., Luo, S., Duncan, M. R., Young, K., Lau, L. F. & Wu, S., Nov 1 2017, In : Pediatric Research. 82, 5, p. 863-871 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Stromal derived factor-1 mediates the lung regenerative effects of mesenchymal stem cells in a rodent model of bronchopulmonary dysplasia

Reiter, J., Drummond, S., Sammour, I., Huang, J., Florea, V., Dornas, P., Hare, J. M., Rodrigues, C. O. & Young, K. C., Jul 12 2017, In : Respiratory research. 18, 1, 137.

Research output: Contribution to journalArticle

16 Scopus citations
2016

Antagonism of stem cell factor/c-kit signaling attenuates neonatal chronic hypoxia-induced pulmonary vascular remodeling

Young, K., Torres, E., Hehre, D., Wu, S., Suguihara, C. & Hare, J., Apr 1 2016, In : Pediatric Research. 79, 4, p. 637-646 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

The effect of gender on mesenchymal stem cell (MSC) efficacy in neonatal hyperoxia-induced lung injury

Sammour, I., Somashekar, S., Huang, J., Batlahally, S., Breton, M., Valasaki, K., Khan, A., Wu, S. & Young, K. C., Oct 2016, In : PloS one. 11, 10, e0164269.

Research output: Contribution to journalArticle

31 Scopus citations
2015

Bone marrow-derived c-kit+ cells attenuate neonatal hyperoxia-induced lung injury

Ramachandran, S., Suguihara, C., Drummond, S., Chatzistergos, K., Klim, J., Torres, E., Huang, J., Hehre, D., Rodrigues, C. D., McNiece, I. K., Hare, J. & Young, K., Jan 1 2015, In : Cell Transplantation. 24, 1, p. 85-95 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

CXCR4 blockade attenuates hyperoxia-induced lung injury in neonatal rats

Drummond, S., Ramachandran, S., Torres, E., Huang, J., Hehre, D., Suguihara, C. & Young, K. C., Jun 9 2015, In : Neonatology. 107, 4, p. 304-311 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Long-term reparative effects of mesenchymal stem cell therapy following neonatal hyperoxia-induced lung injury

Sutsko, R. P., Young, K. C., Ribeiro, A., Torres, E., Rodriguez, M., Hehre, D., Devia, C., McNiece, I. & Suguihara, C., Jan 1 2013, In : Pediatric Research. 73, 1, p. 46-53 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Stem cell factor improves lung recovery in rats following neonatal hyperoxia-induced lung injury

Miranda, L. F., Rodrigues, C. O., Ramachandran, S., Torres, E., Huang, J., Klim, J., Hehre, D., McNiece, I., Hare, J. M., Suguihara, C. Y. & Young, K. C., Dec 1 2013, In : Pediatric Research. 74, 6, p. 682-688 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2012

Antagonism of CXCR7 attenuates chronic hypoxia-induced pulmonary hypertension

Sartina, E., Suguihara, C., Ramchandran, S., Nwajei, P., Rodriguez, M., Torres, E., Hehre, D., Devia, C., Walters, M. J., Penfold, M. E. T. & Young, K. C., Jun 1 2012, In : Pediatric Research. 71, 6, p. 682-688 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
2010

Toll-like receptor 4deficient mice are resistant to chronic hypoxia-induced pulmonary hypertension

Young, K. C., Hussein, S. M. A., Dadiz, R., Demello, D., Devia, C., Hehre, D. & Suguihara, C., Mar 15 2010, In : Experimental Lung Research. 36, 2, p. 111-119 9 p.

Research output: Contribution to journalArticle

27 Scopus citations
2009

Inhibition of the SDF-1/CXCR4 axis attenuates neonatal hypoxia-induced pulmonary hypertension

Young, K. C., Torres, E., Hatzistergos, K. E., Hehre, D., Suguihara, C. & Hare, J. M., Jun 5 2009, In : Circulation research. 104, 11, p. 1293-1301 9 p.

Research output: Contribution to journalArticle

68 Scopus citations
2008

Newborn Girl with Massive Hepatomegaly, Anemia, and Thrombocytopenia

Thompson, S. M., Dadiz, R., Young, K., Teomete, U., Toledano, S. & Rodriguez, M. M., Jan 1 2008, In : Journal of Pediatrics. 152, 1, p. 129-132 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
2005

Effects of a nebulized NONOate, DPTA/NO, on group B Streptococcus-induced pulmonary hypertension in newborn piglets

Dabrowska, K., Hehre, D., Young, K. C., Navarette, C., Ladino, J. F., Bancalari, E. & Suguihara, C., Mar 1 2005, In : Pediatric Research. 57, 3, p. 378-383 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

The association between early tracheal colonization and bronchopulmonary dysplasia

Young, K. C., del Moral, T., Claure, N., Vanbuskirk, S. & Bancalari, E., Jun 1 2005, In : Journal of Perinatology. 25, 6, p. 403-407 5 p.

Research output: Contribution to journalArticle

19 Scopus citations
2004

The effect of a nebulized NO donor, DPTA/NO, on acute hypoxic pulmonary hypertension in newborn piglets

Young, K. C., Ladino, J., Navarrete, C., Dabrowska, K., Hehre, D., Bancalari, E. & Suguihara, C., Apr 16 2004, In : Biology of the Neonate. 85, 3, p. 195-202 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
2003

The role of endothelin converting enzyme inhibition during group B Streptococcus-induced pulmonary hypertension in newborn piglets

Navarrete, C. T., Devia, C., Lessa, A. C., Hehre, D., Young, K., Martinez, O., Bancalari, E. & Suguihara, C., Sep 1 2003, In : Pediatric Research. 54, 3, p. 387-392 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2002

Reye's syndrome in a 17-year-old male: Is this disease really disappearing?

Da Silveira, E. B. V., Young, K., Rodriguez, M. & Ameen, N., Sep 1 2002, In : Digestive Diseases and Sciences. 47, 9, p. 1959-1961 3 p.

Research output: Contribution to journalArticle

3 Scopus citations