Karen Young

Associate Professor of Clinical

  • 270 Citations
20022018
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  • 6 Similar Profiles
Hyperoxia Medicine & Life Sciences
Lung Injury Medicine & Life Sciences
Pulmonary Hypertension Medicine & Life Sciences
Bronchopulmonary Dysplasia Medicine & Life Sciences
Lung Medicine & Life Sciences
Blood Vessels Medicine & Life Sciences
Placebos Medicine & Life Sciences
Right Ventricular Hypertrophy Medicine & Life Sciences

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Projects 2009 2014

Pulmonary Hypertension
Stem Cells
Lung
Hares
Medicine

Research Output 2002 2018

  • 270 Citations
  • 22 Article
  • 1 Chapter
  • 1 Comment/debate
1 Citation (Scopus)

Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth

Donda, K., Zambrano, R., Moon, Y., Percival, J., Vaidya, R., Dapaah-Siakwan, F., Luo, S., Duncan, M. R., Bao, Y., Wang, L., Qin, L., Benny, M., Young, K. & Wu, S., Jul 1 2018, In : PLoS One. 13, 7, e0199927.

Research output: Contribution to journalArticle

hyperoxia
Hyperoxia
Bone Development
Lung Injury
Pulmonary Hypertension

TNFα-stimulated protein 6 (TSG-6) reduces lung inflammation in an experimental model of bronchopulmonary dysplasia

Bryan, C., Sammour, I., Guerra, K., Sharma, M., Dapaah-Siakwan, F., Huang, J., Zambrano, R., Benny, M., Wu, S. & Young, K., Jan 1 2018, (Accepted/In press) In : Pediatric Research.

Research output: Contribution to journalArticle

Bronchopulmonary Dysplasia
Adenoviridae
Pneumonia
Theoretical Models
Hyperoxia
7 Citations (Scopus)

Inhibition of Rac1 Signaling Downregulates Inflammasome Activation and Attenuates Lung Injury in Neonatal Rats Exposed to Hyperoxia

Hummler, J. K., Dapaah-Siakwan, F., Vaidya, R., Zambrano, R., Luo, S., Chen, S., Kerr, N., de Rivero Vaccari, J. P. P., Keane, R., Dalton Dietrich, W., Bancalari, E., Young, K. & Wu, S., Mar 1 2017, In : Neonatology. 111, 3, p. 280-288 9 p.

Research output: Contribution to journalArticle

Inflammasomes
Hyperoxia
Lung Injury
Bronchopulmonary Dysplasia
Down-Regulation
6 Citations (Scopus)

Intra-amniotic soluble endoglin impairs lung development in neonatal rats

Somashekar, S. T., Sammour, I., Huang, J., Dominguez-Bendala, J., Pastori, R., Alvarez-Cubela, S., Torres, E., Wu, S. & Young, K., Oct 1 2017, In : American Journal of Respiratory Cell and Molecular Biology. 57, 4, p. 468-476 9 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Rats
Adenoviridae
Lung
Amniotic Fluid
4 Citations (Scopus)

Recombinant CCN1 prevents hyperoxia-induced lung injury in neonatal rats

Vaidya, R., Zambrano, R., Hummler, J. K., Luo, S., Duncan, M. R., Young, K., Lau, L. F. & Wu, S., Nov 1 2017, In : Pediatric Research. 82, 5, p. 863-871 9 p.

Research output: Contribution to journalArticle

Hyperoxia
Lung Injury
Right Ventricular Hypertrophy
CCN Intercellular Signaling Proteins
Blood Vessels