Jaime R Merchan

Associate Professor

  • 5550 Citations
19982018
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  • 9 Similar Profiles
Neoplasms Medicine & Life Sciences
gemcitabine Medicine & Life Sciences
Measles virus Medicine & Life Sciences
Renal Cell Carcinoma Medicine & Life Sciences
Deoxyglucose Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Oncolytic Viruses Medicine & Life Sciences
15-hydroxyprostaglandin dehydrogenase Medicine & Life Sciences

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Projects 2006 2017

Oncolytic Viruses
Neoplasms
Viruses
Measles virus
Oncogenic Viruses
Kidney Neoplasms
Vascular Endothelial Growth Factor A
Renal Cell Carcinoma
Biomarkers
Therapeutics

Research Output 1998 2018

  • 5550 Citations
  • 44 Article
  • 1 Chapter
1 Citations (Scopus)

Notch pathway inhibition with LY3039478 in soft tissue sarcoma and gastrointestinal stromal tumours

Mir, O., Azaro, A., Merchan, J. R., Chugh, R., Trent, J., Rodon, J., Ohnmacht, U., Diener, J. T., Smith, C., Yuen, E., Oakley, G. J., Le Cesne, A., Soria, J. C., Benhadji, K. A. & Massard, C., Nov 1 2018, In : European Journal of Cancer. 103, p. 88-97 10 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Sarcoma
Leiomyosarcoma
Safety
Disease-Free Survival

The nab-paclitaxel/gemcitabine regimen for patients with refractory advanced pancreatic adenocarcinoma

Palacio, S., Hosein, P., Reis, I., Akunyili, I. I., Ernani, V., Pollack, T., Macintyre, J., Restrepo, M. H., Merchan, J. R. & Lima, C. M. R., Feb 1 2018, In : Journal of Gastrointestinal Oncology. 9, 1, p. 135-139 5 p.

Research output: Contribution to journalArticle

gemcitabine
Adenocarcinoma
Pancreatic Neoplasms
Disease-Free Survival
Survival
1 Citations (Scopus)

Molecular effects of stromal-selective targeting by uPAR-retargeted oncolytic virus in breast cancer

Jing, Y., Chavez, V., Ban, Y., Acquavella, N., El-Ashry, D., Pronin, A., Chen, X. & Merchan, J. R., Oct 1 2017, In : Molecular Cancer Research. 15, 10, p. 1410-1420 11 p.

Research output: Contribution to journalArticle

Oncolytic Viruses
Measles virus
Breast Neoplasms
Neoplasms
Viruses
15 Citations (Scopus)

Percutaneous Image-Guided Irreversible Electroporation for the Treatment of Unresectable, Locally Advanced Pancreatic Adenocarcinoma

Narayanan, G., Hosein, P., Beulaygue, I. C., Froud, T., Scheffer, H. J., Venkat, S., Echenique, A., Hevert, E. C., Livingstone, A., Rocha-Lima, C. M., Merchan, J. R., Levi, J., Yrizarry, J. & Lencioni, R., Mar 1 2017, In : Journal of Vascular and Interventional Radiology. 28, 3, p. 342-348 7 p.

Research output: Contribution to journalArticle

Electroporation
Adenocarcinoma
Survival
Safety
Therapeutics
11 Citations (Scopus)

2-deoxy-glucose downregulates endothelial AKT and ERK via interference with N-linked glycosylation, induction of endoplasmic reticulum stress, and GSK3β activation

Kovacs, K., Decatur, C., Toro, M., Pham, D. G., Liu, H., Jing, Y., Murray, T. G., Lampidis, T. & Merchan, J. R., Feb 1 2016, In : Molecular Cancer Therapeutics. 15, 2, p. 264-275 12 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Deoxyglucose
Glycosylation
Down-Regulation
Endothelial Cells