J. William Harbour

Professor

  • 9653 Citations
1988 …2022
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  • 5 Similar Profiles
Retinoblastoma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Melanoma Medicine & Life Sciences
Neoplasm Metastasis Medicine & Life Sciences
Uveal Neoplasms Medicine & Life Sciences
Mutation Medicine & Life Sciences
Uveal melanoma Medicine & Life Sciences
Retinoblastoma Protein Medicine & Life Sciences

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Projects 1998 2022

Molecular Predictive Testing in Ocular Melanoma

William Harbour, J.

National Institutes of Health

7/1/063/31/22

Project: Research projectResearch Project

Melanoma
Neoplasms
Neoplasm Micrometastasis
Biomarkers
Therapeutics

THE GENETICS OF OCULAR MELANOMA

William Harbour, J. & Bowcock, A. M.

National Institutes of Health

7/1/114/30/16

Project: Research projectResearch Project

Melanoma
Chromosomes, Human, Pair 3
Mutation
Neoplasms
Neoplasm Metastasis

THE ROLE OF RB IN THE RETINA &OTHER TISSUES

William Harbour, J.

National Institutes of Health

7/1/001/31/11

Project: Research projectResearch Project

Retina
Phosphorylation
Cell Death
Cell Proliferation
Melanocytes

FUNCTIONAL ANALYSIS OF THE RETINAL REGULATORY PROTEIN RB

William Harbour, J.

National Institutes of Health

1/1/9812/31/02

Project: Research projectClinical Investigator Award (CIA)

Retinoblastoma Protein
Retina
Retinal Neoplasms
E2F Transcription Factors
cdc Genes

Research Output 1988 2018

Are Risk Factors for Growth of Choroidal Nevi Associated With Malignant Transformation? Assessment With a Validated Genomic Biomarker

William Harbour, J., Paez-Escamilla, M., Cai, L., Walter, S. D., Augsburger, J. J. & Correa, Z. M., Jan 1 2018, (Accepted/In press) In : American journal of ophthalmology.

Research output: Contribution to journalArticle

Nevus
Biomarkers
Growth
Neoplasms
Transcriptome
Choroidal Neovascularization
Retinal Pigment Epithelium
Hypertrophy
Intravitreal Injections
San Francisco

Diagnosis of bilateral retinocytoma in an adolescent patient using multimodal imaging and genetic testing

Paez-Escamilla, M., Walter, S. D., Ramaiya, K. J. & William Harbour, J., Oct 1 2018, In : Ophthalmic Surgery Lasers and Imaging Retina. 49, 10, p. 812-814 3 p.

Research output: Contribution to journalArticle

Retinal Neoplasms
Multimodal Imaging
Genetic Testing
Retinoblastoma Genes
Tuberous Sclerosis
3 Citations

Familial and somatic BAP1 mutations inactivate ASXL1/2-mediated allosteric regulation of BAP1 deubiquitinase by targeting multiple independent domains

Peng, H., Prokop, J., Karar, J., Park, K., Cao, L., William Harbour, J., Bowcock, A. M., Malkowicz, S. B., Cheung, M., Testa, J. R. & Rauscher, F. J., Mar 1 2018, In : Cancer Research. 78, 5, p. 1200-1213 14 p.

Research output: Contribution to journalArticle

Allosteric Regulation
Mutation
Ubiquitin Thiolesterase
Polycomb-Group Proteins
Tumor Suppressor Proteins
11 Citations

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Yang, H., Kurtenbach, S., Guo, Y., Lohse, I., Durante, M. A., Li, J., Li, Z., Al-Ali, H., Li, L., Chen, Z., Field, M. G., Zhang, P., Chen, S., Yamamoto, S., Li, Z., Zhou, Y., Nimer, S. D., William Harbour, J., Wahlestedt, C. R., Xu, M. & 1 othersYang, F-C., Jan 18 2018, In : Blood. 131, 3, p. 328-341 14 p.

Research output: Contribution to journalArticle

Comb and Wattles
Stem cells
Liquid chromatography
Chromatin
Mass spectrometry