Hans P Larsson

Professor

  • 2993 Citations
1993 …2020
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  • 4 Similar Profiles
Amino Acid Transport System X-AG Medicine & Life Sciences
Protons Medicine & Life Sciences
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Medicine & Life Sciences
Glutamic Acid Medicine & Life Sciences
Ion Channels Medicine & Life Sciences
Voltage-Gated Potassium Channels Medicine & Life Sciences
Fluorometry Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Projects 2002 2020

Anti-Arrhythmia Agents
Unsaturated Fatty Acids
Cardiac Myocytes
Long QT Syndrome
Action Potentials

Modulation of KCNQ1 channel activity

Larsson, H. P. & Kass, R.

National Institutes of Health

5/1/1412/31/18

Project: Research project

Mutation
KCNQ1 Potassium Channel
Cardiac Arrhythmias
Long QT Syndrome
Deafness
Protons
Asthma
Immune System
Blood Cells
Dimerization
Amino Acid Transport System X-AG
Glutamic Acid
Structural Models
Poisons
Synapses
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Ion Channels
Potassium Channels
Cysteine
Action Potentials

Research Output 1993 2018

  • 2993 Citations
  • 64 Article
  • 1 Comment/debate
1 Citation (Scopus)

Gating charge displacement in a monomeric voltage-gated proton (Hv1) channel

Carmona, E. M., Larsson, H. P., Neely, A., Alvarez, O., Latorre, R. & Gonzalez, C., Sep 11 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 37, p. 9240-9245 6 p.

Research output: Contribution to journalArticle

Protons
Insulator Elements
Ions
Physiological Phenomena
Arginine

KCNE1 tunes the sensitivity of Kv7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site

Larsson, J. E., Larsson, H. P. & Liin, S. I., Jul 17 2018, In : eLife. 7, e37257.

Research output: Contribution to journalArticle

Unsaturated Fatty Acids
Binding Sites
Protonation
Anti-Arrhythmia Agents
Essential Drugs
1 Citation (Scopus)

Mechanisms Underlying the Dual Effect of Polyunsaturated Fatty Acid Analogs on Kv7.1

Liin, S. I., Yazdi, S., Ramentol, R., Barro, R. & Larsson, H. P., Sep 11 2018, In : Cell Reports. 24, 11, p. 2908-2918 11 p.

Research output: Contribution to journalArticle

Unsaturated Fatty Acids
Anti-Arrhythmia Agents
Electric potential
KCNQ1 Potassium Channel
S 6
3 Citations (Scopus)

Mutations in ATP1A1 Cause Dominant Charcot-Marie-Tooth Type 2

Lassuthova, P., Rebelo, A. P., Ravenscroft, G., Lamont, P. J., Davis, M. R., Manganelli, F., Feely, S. M., Bacon, C., Brožková, D. Š., Haberlova, J., Mazanec, R., Tao, F., Saghira, C., Abreu, L., Courel, S., Powell, E., Buglo, E., Bis, D. M., Baxter, M. F., Ong, R. W. & 14 othersMarns, L., Lee, Y. C., Bai, Y., Isom, D., Barro, R., Chung, K. W., Scherer, S. S., Larsson, H. P., Laing, N. G., Choi, B. O., Seeman, P., Shy, M. E., Santoro, L. & Zuchner, S. L., Mar 1 2018, In : American Journal of Human Genetics. 102, 3, p. 505-514 10 p.

Research output: Contribution to journalArticle

Axons
Tooth
Mutation
Information Dissemination
Genetic Association Studies
1 Citation (Scopus)

ω-6 and ω-9 polyunsaturated fatty acids with double bonds near the carboxyl head have the highest affinity and largest effects on the cardiac IK s potassium channel

Bohannon, B. M., Perez, M. E., Liin, S. I. & Larsson, H. P., Jan 1 2018, (Accepted/In press) In : Acta Physiologica. e13186.

Research output: Contribution to journalArticle

Intermediate-Conductance Calcium-Activated Potassium Channels
Unsaturated Fatty Acids
Long QT Syndrome
Head
Action Potentials