Guy Howard

Research Professor

  • 4451 Citations
1978 …2016

Research output per year

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Research Output

  • 4451 Citations
  • 83 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Review article
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Article

17β Estradiol stimulation of endosteal bone formation in the ovariectomized mouse: An animal model for the evaluation of bone-targeted estrogens

Edwards, M. W., Bain, S. D., Bailey, M. C., Lantry, M. M. & Howard, G. A., 1992, In : Bone. 13, 1, p. 29-34 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

24R,25-Dihydroxyvitamin D3 promotes the osteoblastic differentiation of human mesenchymal stem cells

Curtis, K. M., Aenlle, K. K., Roos, B. A. & Howard, G. A., May 2014, In : Molecular Endocrinology. 28, 5, p. 644-658 15 p.

Research output: Contribution to journalArticle

33 Scopus citations

2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer

Qadan, L. R., Perez-Stable, C. M., Anderson, C., D'Ippolito, G., Herron, A., Howard, G. A. & Roos, B. A., Jan 1 2001, In : Biochemical and biophysical research communications. 285, 5, p. 1259-1266 8 p.

Research output: Contribution to journalArticle

85 Scopus citations

Absence of androgen-mediated transcriptional effects in osteoblastic cells despite presence of androgen receptors

Czerwiec, F. S., Liaw, J. J., Liu, S. B., Perez-Stable, C., Grumbles, R., Howard, G. A., Roos, B. A. & Burnstein, K. L., Jul 1 1997, In : Bone. 21, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Acetate inhibition of chick bone cell proliferation and bone growth in vitro

Saitta, J. C., Lipkin, E. W. & Howard, G. A., Jun 1989, In : Journal of Bone and Mineral Research. 4, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow

D'Ippolito, G., Schiller, P. C., Ricordi, C., Roos, B. A. & Howard, G. A., Jul 17 1999, In : Journal of Bone and Mineral Research. 14, 7, p. 1115-1122 8 p.

Research output: Contribution to journalArticle

691 Scopus citations

Anabolic or catabolic responses of MC3T3-E1 osteoblastic cells to parathyroid hormone depend on time and duration of treatment

Schiller, P. C., D'Ippolito, G., Roos, B. A. & Howard, G. A., Sep 13 1999, In : Journal of Bone and Mineral Research. 14, 9, p. 1504-1512 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

An Assessment of the Anabolic Skeletal Actions of the Common‐Region Peptides Derived from the CGRP and Calcitonin Prohormones

BURNS, DOUGLAS. M., HOWARD, GUY. A. & Roos, B. A., Jun 1992, In : Annals of the New York Academy of Sciences. 657, 1, p. 50-62 13 p.

Research output: Contribution to journalArticle

8 Scopus citations
22 Scopus citations

An improved technique for rapid autoradiography of cells and tissue sections

Langager, J. M., Howard, G. A. & Baylink, D. J., Dec 1982, In : Histochemistry. 75, 4, p. 523-531 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Autosomal dominant hyperostosis/osteosclerosis with high serum alkaline phosphatase activity

Hernandez-Cassis, C., Vogel, C. K., Hernandez, T. P., Econs, M. J., Iglesias, M., Iglesias, A., Levis, S., Roos, B. A., Howard, G. A. & Gamarra, A. I., Jun 1 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2650-2655 6 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
30 Scopus citations

Bone‐cell changes in estrogen‐induced bone‐mass increase in mice: Dissociation of osteoclasts from bone surfaces

Liu, CC. C. & Howard, G. A., Feb 1991, In : The Anatomical Record. 229, 2, p. 240-250 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Bone cells, bone metabolism and cGMP.

Howard, G. A., Jan 1 1985, In : Progress in clinical and biological research. 187, p. 67-76 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Bone Cells on Microcarrier Spheres

Howard, G. A., Turner, R. T., Puzas, J. E., Nichols, F. & Baylink, D. J., Jan 14 1983, In : JAMA: The Journal of the American Medical Association. 249, 2, p. 258-259 2 p.

Research output: Contribution to journalArticle

10 Scopus citations

Bone mineralization and metabolism of3H-25-hydroxyvitamin D3 in thyroparathyroidectomized rats treated with parathyroid extract

Rader, J. I., Howard, G. A., Feist, E., Turner, R. T. & Baylink, D. J., Dec 1 1979, In : Calcified Tissue International. 29, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Bone resorption in vitro: Effects of a physiologic dose of parathyroid hormone

Howard, G. A., Bottemiller, B. L. & Baylink, D. J., Jan 1 1979, In : Clinical Research. 27, 1, p. 46A

Research output: Contribution to journalArticle

Calcitonin gene-related peptide (cgrp) in the developing mouse limb

Bidegain, M., Roos, B. A., Hill, E. L., Howard, G. A. & Balkan, W., Jan 1995, In : Endocrine Research. 21, 4, p. 743-755 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Calcitonin gene-related peptide is an adipose-tissue neuropeptide with lipolytic actions

Chatzipanteli, K., Goldbergt, R. B., Howard, G. A. & Roos, B. A., Jan 1 1996, In : Endocrinology and Metabolism, Supplement. 3, 4, p. 235-242 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Calcitonin gene-related peptide rapidly inhibits calcium uptake in osteoblastic cell lines via activation of adenosine triphosphate-sensitive potassium channels

Kawase, T., Howard, G. A., Roos, B. A. & Burns, D. M., Jan 1 1996, In : Endocrinology. 137, 3, p. 984-990 7 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Calvarial Cells Synthesize 1α,25-Dihydroxyvitamin D3 from 25-Hydroxyvitamin D3

Turner, R. T., Turner, R. T., Knapp, D. R., Howard, G. A., Puzas, J. E. & Baylink, D. J., Jan 1 1983, In : Biochemistry. 22, 5, p. 1073-1076 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Cartilage metalloproteases in disuse atrophy

Grumbles, R. M., Howell, D. S., Howard, G. A., Roos, B. A., Setton, L. A., Mow, C., Ratcliffe, A., Muller, F. J. & Altman, R. D., Jan 1 1995, In : Journal of Rheumatology. 22, SUPPL. 43, p. 146-148 3 p.

Research output: Contribution to journalArticle

35 Scopus citations

Cells isolated from embryonic intestine synthesize 1,25-Dihydroxyvitamin-D3 and 24,25-dihydroxyvitamin-D3 in culture

Puzas, J. E., Turner, R. T., Howard, G. A. & Baylinko, D. J., Jan 1983, In : Endocrinology. 112, 1, p. 378-380 3 p.

Research output: Contribution to journalArticle

16 Scopus citations

Changes in the expression of genes associated with intraneuronal amyloid-β and tau in Alzheimer's disease

Fujimura, R. K., Reiner, T., Ma, F., Phillips, V., De Las Pozas, A., Dickson, D. W., Roos, B. A., Howard, G. A. & Perez-Stable, C., 2010, In : Journal of Alzheimer's Disease. 19, 1, p. 97-109 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
58 Scopus citations

Coupled bone metabolism in vitro: embryonic chick limbs in organ culture.

Howard, G. A., Carlson, C. A. & Baylink, D. J., Dec 1 1982, In : Progress in clinical and biological research. 101, p. 259-274 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Coupling factor.

Baylink, D., Farley, J., Howard, G., Drivdahl, R., Puzas, E., Masuda, T., Ivey, J. & Gruber, H., 1982, In : Advances in experimental medicine and biology. 151, p. 409-421 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Cyclosporin A affects extracellular matrix synthesis and degradation by mouse MC3T3-E1 osteoblasts in vitro

Fornoni, A., Cornacchia, F., Howard, G. A., Roos, B. A., Striker, G. E. & Striker, L. J., Jan 1 2001, In : Nephrology Dialysis Transplantation. 16, 3, p. 500-505 6 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Development and reversibility of aluminum-induced bone lesion in the rat

Ott, S. M., Feist, E., Andress, D. L., Liu, C. C., Sherrard, D. J., Alfrey, A. C., Slatopolsky, E. & Howard, G. A., Mar 17 1987, In : Journal of Laboratory and Clinical Medicine. 109, 1, p. 40-47 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Development and reversibility of aluminum-induced bone lesion in the rat

Ott, S. M., Feist, E., Andress, D. L., Liu, C. C., Sherrard, D. J., Alfrey, A. C., Slatopolsky, E. & Howard, G. A., Jan 1987, In : The Journal of Laboratory and Clinical Medicine. 109, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Diverse actions of calcitonin gene-related peptide on intracellular free Ca2+ concentrations in UMR 106 osteoblastic cells

Kawase, T., Howard, G. A., Roos, B. A. & Burns, D. M., Apr 1995, In : Bone. 16, 4 SUPPL., p. S379-S384

Research output: Contribution to journalArticle

24 Scopus citations
1 Scopus citations

Endogenous Inhibitor of Bone Cell Proliferation

Puzas, J. E., Drivdahl, R. H., Howard, G. A. & Baylink, D. J., Jan 1981, In : Proceedings of the Society for Experimental Biology and Medicine. 166, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Ethanol inhibits human bone cell proliferation and function in vitro

Friday, K. E. & Howard, G. A., Jun 1991, In : Metabolism. 40, 6, p. 562-565 4 p.

Research output: Contribution to journalArticle

103 Scopus citations

Evidence for the coupling of bone formation to bone resorption in vitro

Howard, G. A., Bottemiller, B. L. & Baylink, D. J., 1980, In : Metabolic Bone Disease and Related Research. 2, 2, p. 131-135 5 p.

Research output: Contribution to journalArticle

65 Scopus citations

Extracts of bone contain a potent regulator of bone formation

Drivdahl, R. H., Howard, G. A. & Baylink, D. J., Jan 12 1982, In : BBA - General Subjects. 714, 1, p. 26-33 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by cAMP

Mehta, P. P., Lokeshwar, B. L., Schiller, P. C., Bendix, M. V., Ostenson, R. C., Howard, G. A. & Roos, B. A., Jan 1 1996, In : Molecular Carcinogenesis. 15, 1, p. 18-32 15 p.

Research output: Contribution to journalArticle

65 Scopus citations

Gap-junctional communication is required for the maturation process of osteoblastic cells in culture

Schiller, P. C., D'Ippolito, G., Balkan, W., Roos, B. A. & Howard, G. A., May 10 2001, In : Bone. 28, 4, p. 362-369 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

Gap-junctional communication mediates parathyroid hormone stimulation of mineralization in osteoblastic cultures

Schiller, P. C., D'Ippolito, G., Balkan, W., Roos, B. A. & Howard, G. A., Feb 13 2001, In : Bone. 28, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

67 Scopus citations

Glycosylation reduces the bioactivity of calcitonin

Gkonos, P. J., Charbonneau, H., Lawson, P. T., Howard, G. A., Birnbaum, R. S. & Roos, B. A., Jan 1 1989, In : Peptides. 10, 1, p. 137-143 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hepatocyte growth factor (HGF) and 1,25-dihydroxyvitamin D together stimulate human bone marrow-derived stem cells toward the osteogenic phenotype by HGF-induced up-regulation of VDR

Chen, K., Aenlle, K. K., Curtis, K. M., Roos, B. A. & Howard, G. A., Jul 1 2012, In : Bone. 51, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Hepatocyte growth factor and its actions in growth plate chondrocytes

Grumbles, R. M., Howell, D. S., Wenger, L., Altman, R. D., Howard, G. A. & Roos, B. A., Sep 1996, In : Bone. 19, 3, p. 255-261 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Hepatocyte growth factor and p38 promote osteogenic differentiation of human mesenchymal stem cells

Aenlle, K. K., Curtis, K. M., Roos, B. A. & Howard, G. A., May 2014, In : Molecular Endocrinology. 28, 5, p. 722-730 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hepatocyte growth factor and vitamin D cooperatively inhibit androgen-unresponsive prostate cancer cell lines

Qadan, L. R., Perez-Stable, C. M., Schwall, R. H., Burnstein, K. L., Ostenson, R. C., Howard, G. A. & Roos, B. A., Jan 1 2000, In : Endocrinology. 141, 7, p. 2567-2573 7 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Heterotopic bone formation after operation: A quantitative histologic and biochemical study

Puzas, J. E., Brand, J. S. & Howard, G. A., Jan 1 1984, In : Surgical forum. VOL. 35, p. 521-523 3 p.

Research output: Contribution to journalArticle

7 Scopus citations
Open Access
121 Scopus citations

Human bone cells in culture metabolize 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3

Howard, G. A., Turner, R. T., Sherrard, D. J. & Baylink, D. J., Dec 1 1981, In : Journal of Biological Chemistry. 256, 15, p. 7738-7740 3 p.

Research output: Contribution to journalArticle

183 Scopus citations

Human bone marrow-derived stem cell proliferation is inhibited by hepatocyte growth factor via increasing the cell cycle inhibitors p53, p21 and p27

Chen, K., Perez-Stable, C., D'Ippolito, G., Schiller, P. C., Roos, B. A. & Howard, G. A., Dec 1 2011, In : Bone. 49, 6, p. 1194-1204 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Identification of 1,25(OH)2D3 produced by bone cells in culture using mass spectrometry

Howard, G. A., Turner, R. T. & Puzas, J. E., Jan 1 1982, In : Clinical Research. 30, 2, p. 395A

Research output: Contribution to journalArticle

Identification of a low molecular weight inhibitor of osteoblast mitogenesis in uremic plasma

Andress, D. L., Howard, G. A. & Birnbaum, R. S., May 1991, In : Kidney international. 39, 5, p. 942-945 4 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations