Glen N Barber

Professor

  • 15418 Citations
1986 …2020
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Projects 1997 2020

Vesicular Stomatitis
Virus Replication
Viruses
Interferons
Glioblastoma

Host Defense and the Regulation of Interferon Production

Barber, G. N.

National Institutes of Health

8/1/0810/31/19

Project: Research projectResearch Project, High Priority, Short Term Project Award

Innate Immunity
Interferons
Toll-Like Receptors
Interferon Type I
Virus Diseases

Regulation of Innate Immune Responses

Barber, G. N., Harhaj, E., Rosenblatt, J. D., Ruiz, P. & Guettouche, T.

National Institutes of Health

7/1/097/31/14

Project: Research projectResearch Program Projects

Human T-lymphotropic virus 1
Melanoma-Specific Antigens
Innate Immunity
Differentiation Antigens
Carcinogenesis

Innate Intracellular Mechanisms

Barber, G. N.

National Institutes of Health

5/22/094/30/11

Project: Research projectResearch Project

Receptor-Interacting Protein Serine-Threonine Kinases
Death Domain Receptors
Virus Diseases
Protein Kinases
Microbial Genes

Evaluation of Novel DExD/H Helicases in Innate Immune Signaling

Barber, G. N.

National Institutes of Health

5/1/094/30/14

Project: Research projectResearch Project--Cooperative Agreements

Fas-Associated Death Domain Protein
Virus Diseases
Interferons
Melanoma-Specific Antigens
Differentiation Antigens

Research Output 1986 2018

7 Citations

Brucella abortus Triggers a cGAS-Independent STING Pathway to Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation

Franco, M. M. C., Marim, F., Guimarães, E. S., Assis, N. R. G., Cerqueira, D. M., Alves-Silva, J., Harms, J., Splitter, G., Smith, J., Kanneganti, T. D., De Queiroz, N. M. G. P., Gutman, D., Barber, G. N. & Oliveira, S. C., Jan 15 2018, In : Journal of Immunology. 200, 2, p. 607-622 16 p.

Research output: Contribution to journalArticle

GMP synthase (glutamine-hydrolyzing)
Inflammasomes
Brucella abortus
Brucella
Carrier Proteins

Combating herpesvirus encephalitis by potentiating a TLR3–mTORC2 axis

Sato, R., Kato, A., Chimura, T., Saitoh, S. I., Shibata, T., Murakami, Y., Fukui, R., Liu, K., Zhang, Y., Arii, J., Sun-Wada, G. H., Wada, Y., Ikenoue, T., Barber, G. N., Manabe, T., Kawaguchi, Y. & Miyake, K., Oct 1 2018, In : Nature Immunology. 19, 10, p. 1071-1082 12 p.

Research output: Contribution to journalArticle

Herpesviridae
Human Herpesvirus 1
Encephalitis
Infection
Herpes Simplex Encephalitis
5 Citations

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

Takahashi, A., Loo, T. M., Okada, R., Kamachi, F., Watanabe, Y., Wakita, M., Watanabe, S., Kawamoto, S., Miyata, K., Barber, G. N., Ohtani, N. & Hara, E., Dec 1 2018, In : Nature Communications. 9, 1, 1249.

Research output: Contribution to journalArticle

phenotype
Deoxyribonucleases
Down-Regulation
deoxyribonucleic acid
Phenotype
1 Citations

Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells

Ahn, J., Xia, T., Rabasa Capote, A., Betancourt, D. & Barber, G. N., Jan 1 2018, (Accepted/In press) In : Cancer Cell.

Research output: Contribution to journalArticle

Phagocytes
Interferons
Antigen-Presenting Cells
Cross-Priming
Genes
4 Citations

Oncolytic Viruses as Antigen-Agnostic Cancer Vaccines

Russell, S. J. & Barber, G. N., Apr 9 2018, In : Cancer Cell. 33, 4, p. 599-605 7 p.

Research output: Contribution to journalReview article

Oncolytic Viruses
Cancer Vaccines
Antigens
Cytotoxic T-Lymphocytes
Immunity