George Munson

Associate Professor

  • 890 Citations
1990 …2019
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Enterotoxigenic Escherichia coli Medicine & Life Sciences
Virulence Medicine & Life Sciences
Binding Sites Medicine & Life Sciences
Genes Medicine & Life Sciences
Hot Temperature Medicine & Life Sciences
Cyclic AMP Receptor Protein Medicine & Life Sciences
Enterotoxins Medicine & Life Sciences
Activator Appliances Medicine & Life Sciences

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Projects 1999 2019

Enterotoxigenic Escherichia coli
Virulence Factors
Enterotoxins
Diarrhea
Hot Temperature

Killing of intracellular bacteria by Perforin-2

Podack, E. R. & Munson, G.

National Institutes of Health

12/1/1411/30/19

Project: Research project

Bacteria
Phagocytes
perforin 2
Small Interfering RNA
Reactive Nitrogen Species
Virulence Factors
Virulence
Enterotoxigenic Escherichia coli
Gastrointestinal Tract
Diarrhea
Enterotoxigenic Escherichia coli
Virulence
Binding Sites
Transcription Initiation Site
Homeostasis

Research Output 1990 2018

  • 890 Citations
  • 27 Article
  • 1 Review article
1 Citation (Scopus)

Perforin-2 breaches the envelope of phagocytosed bacteria allowing antimicrobial effectors access to intracellular targets

Bai, F., McCormack, R. M., Hower, S., Plano, G. V., Lichtenheld, M. G. & Munson, G., Nov 1 2018, In : Journal of Immunology. 201, 9, p. 2710-2720 11 p.

Research output: Contribution to journalArticle

Phagocytosis
Bacteria
Peptide Hydrolases
Salmonella enterica
Phagocytes
7 Citations (Scopus)

Killing of microbes and cancer by the immune system with three mammalian pore-forming killer proteins

Podack, E. R. & Munson, G., Nov 3 2016, In : Frontiers in Immunology. 7, NOV, 464.

Research output: Contribution to journalReview article

Immune System
Biological Warfare
Porins
Perforin
Extracellular Fluid
2 Citations (Scopus)

The virulence regulator Rns activates the expression of CS14 Pili

Bodero, M. D. R. & Munson, G., Dec 8 2016, In : Genes. 7, 12, 120.

Research output: Contribution to journalArticle

Enterotoxigenic Escherichia coli
Virulence
Fimbriae Proteins
Transcription Initiation Site
Virulence Factors
14 Citations (Scopus)

Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2

McCormack, R. M., Lyapichev, K., Olsson, M. L., Podack, E. R. & Munson, G., Sep 29 2015, In : eLife. 4, September2015, e06505.

Research output: Contribution to journalArticle

Pathogens
Cell Cycle
Cells
Bacteria
Cullin Proteins
17 Citations (Scopus)

Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria

McCormack, R. M., de Armas, L. R., Shiratsuchi, M., Fiorentino, D. G., Olsson, M. L., Lichtenheld, M. G., Morales, A., Lyapichev, K., Gonzalez, L. E., Strbo, N., Sukumar, N., Stojadinovic, O., Plano, G. V., Munson, G., Tomic-Canic, M., Kirsner, R., Russell, D. G. & Podack, E. R., Sep 24 2015, In : eLife. 4, September2015, e06508.

Research output: Contribution to journalArticle

Phagocytes
Bacteria
perforin 2
Reactive Nitrogen Species
Salmonella