Francisco Vega

Professor of Clinical

  • 3675 Citations
19962019

Research output per year

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Research Output

CRISPR genome editing of murine hematopoietic stem cells to create Npm1-Alk causes ALK1 lymphoma after transplantation

Rajan, S. S., Li, L., Kweh, M. F., Kunkalla, K., Amin, A. D., Agarwal, N. K., Vega, F. & Schatz, J. H., Jan 1 2019, In : Blood Advances. 3, 12, p. 1788-1794 7 p.

Research output: Contribution to journalReview article

Open Access

Disseminated cutaneous immunoglobulin M macroglobulinosis associated with cryoglobulinemia and minimal residual disease of Waldenström macroglobulinemia

Fayne, R., Rosenberg, M., White, K., Alencar, A., Kirsner, R. S., Vega, F. & Cho-Vega, J. H., Oct 2019, In : JAAD Case Reports. 5, 10, p. 918-922 5 p.

Research output: Contribution to journalArticle

Open Access

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216), (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., Jermakowicz, A. M., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D. G., Watts, J., Vega, F. & Nimer, S. D., Jan 14 2019, In : Cancer Cell. 35, 1, 1 p.

Research output: Contribution to journalComment/debate

LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL

Parvin, S., Ramirez-Labrada, A., Aumann, S., Lu, X. Q., Weich, N., Santiago, G., Cortizas, E. M., Sharabi, E., Zhang, Y., Sanchez-Garcia, I., Gentles, A. J., Roberts, E., Bilbao-Cortes, D., Vega, F., Chapman, J. R., Verdun, R. E. & Lossos, I. S., Sep 16 2019, In : Cancer Cell. 36, 3, p. 237-249.e6

Research output: Contribution to journalArticle

1 Scopus citations

Long-term overall- and progression-free survival after pentostatin, cyclophosphamide and rituximab therapy for indolent non-Hodgkin lymphoma

Khashab, T., Hagemeister, F., Romaguera, J. E., Fanale, M. A., Pro, B., McLaughlin, P., Rodriguez, M. A., Neelapu, S. S., Fayad, L., Younes, A., Feng, L., Vega, F., Kwak, L. W. & Samaniego, F., May 1 2019, In : British Journal of Haematology. 185, 4, p. 670-678 9 p.

Research output: Contribution to journalArticle

Mechanisms of lymphoma clearance induced by high-dose alkylating agents

Lossos, C., Liu, Y., Kolb, K. E., Christie, A. L., Van Scoyk, A., Prakadan, S. M., Shigemori, K., Stevenson, K. E., Morrow, S., Plana, O. D., Fraser, C., Jones, K. L., Liu, H., Pallasch, C. P., Modiste, R., Nguyen, Q. D., Craig, J. W., Morgan, E. A., Vega, F., Aster, J. C. & 4 others, Sarosiek, K. A., Shalek, A. K., Hemann, M. T. & Weinstock, D. M., Jul 1 2019, In : Cancer Discovery. 9, 7, p. 944-961 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

Recent BCR stimulation induces a negative autoregulatory loop via FBXO10 mediated degradation of HGAL

Guo, F., Luo, Y., Jiang, X., Lu, X. Q., Roberti, D., Lossos, C., Kunkalla, K., Magistri, M., Rui, L., Verdun, R., Vega, F., Moy, V. T. & Lossos, I. S., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Short survival and frequent transformation in extranodal marginal zone lymphoma with multiple mucosal sites presentation

Alderuccio, J. P., Zhao, W., Desai, A., Ramdial, J., Gallastegui, N., Kimble, E., De La Fuente, M. I., Husnain, M., Rosenblatt, J. D., Alencar, A. J., Schatz, J. H., Moskowitz, C., Chapman-Fredricks, J., Vega, F., Reis, I. & Lossos, I., Jan 1 2019, In : American Journal of Hematology.

Research output: Contribution to journalArticle

Unusual Variants of Follicular Lymphoma: Case-based Review

Chapman, J. R., Alvarez, J. P., White, K., Sanchez, S., Khanlari, M., Algashaamy, K., Cassidy, D., Peng, J. H., Fan, Y. S., Alencar, A., Alderuccio, J. P., Lossos, I. S. & Vega, F., Jan 1 2019, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

2018

Adult T-cell leukemia/lymphoma can be indistinguishable from other more common T-cell lymphomas. The University of Miami experience with a large cohort of cases

Khanlari, M., Carlos Ramos, J., Sanchez, S. P., Cho, J. H., Amador, A., Campuzano-Zuluaga, G., Vega, F. & Chapman-Fredricks, J., Feb 15 2018, (Accepted/In press) In : Modern Pathology. p. 1-18 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathais, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schuerer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F-C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Jun 11 2018, In : Cancer Cell. 33, 6, p. 1111-1127.e5

Research output: Contribution to journalArticle

7 Scopus citations

CD4+/CD8+ immunophenotype switching as a marker for intraocular and CNS involvement in mycosis fungoides

Husnain, M., Mackrides, N., Vega, F., Paez-Escamilla, M., Markoe, A., William Harbour, J. & Lossos, I., Jan 1 2018, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

2 Scopus citations
3 Scopus citations

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216) (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Nov 12 2018, In : Cancer Cell. 34, 5, 1 p.

Research output: Contribution to journalComment/debate

Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study

Swords, R. T., Azzam, D., Al-Ali, H., Lohse, I., Volmar, C. H., Watts, J., Perez, A., Rodriguez, A., Vargas, F., Elias, R., Vega, F., Zelent, A. Z., Brothers, S. P., Abbasi, T., Trent, J., Rangwala, S., Deutsch, Y., Conneally, E., Drusbosky, L., Cogle, C. R. & 1 others, Wahlestedt, C. R., Jan 1 2018, In : Leukemia Research. 64, p. 34-41 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Intracytoplasmic azurophilic inclusions in prolymphocytes

Mackrides, N., Lossos, I. & Vega, F., Dec 1 2018, In : International Journal of Hematology. 108, 6, 1 p.

Research output: Contribution to journalComment/debate

Myeloid neoplasms with features intermediate between primary myelofibrosis and chronic myelomonocytic leukemia

Chapman-Fredricks, J., Geyer, J. T., Khanlari, M., Moul, A., Casas, C., Connor, S. T., Fan, Y-S., Watts, J., Swords, R. T., Vega, F. & Orazi, A., Mar 1 2018, In : Modern Pathology. 31, 3, p. 429-441 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prevalence, clinical characteristics and prognosis of EBV-positive follicular lymphoma

Mackrides, N., Chapman, J., Larson, M. C., Ramos, J. C., Toomey, N., Lin, P., Maurer, M. J., Rafaelle, M., Tan, Y., Ikpatt, O., Syrbu, S., Ansell, S. M., Habermann, T. M., Link, B. K., Feldman, A. L., Lossos, I. S., Cerhan, J. R. & Vega, F., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

2 Scopus citations
2 Scopus citations

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

Lu, X., Fernando, T. M., Lossos, C., Yusufova, N., Liu, F., Fontán, L., Durant, M., Geng, H., Melnick, J., Luo, Y., Vega, F., Moy, V. T., Inghirami, G., Nimer, S. D., Melnick, A. M. & Lossos, I., Nov 8 2018, In : Blood. 132, 19, p. 2026-2039 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Rapid complete response to blinatumomab as a successful bridge to allogeneic stem cell transplantation in a case of refractory Richter syndrome

Alderuccio, J. P., Mackrides, N., Chapman-Fredricks, J., Vega, F. & Lossos, I., Apr 18 2018, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-4 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Risk factors for transformation to higher-grade lymphoma and its impact on survival in a large cohort of patients with marginal zone lymphoma from a single institution

Alderuccio, J. P., Zhao, W., Desai, A., Gallastegui, N., Ramdial, J., Kimble, E., De La Fuente, M. I., Rosenblatt, J. D., Chapman-Fredricks, J., Vega, F., Reis, I. & Lossos, I., Dec 1 2018, In : Journal of Clinical Oncology. 36, 34, p. 3370-3380 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role of smoothened with implications in lymphoma biology

Qu, C., Kunkalla, K., Vaghefi, A., Frederiksen, J. K., Liu, Y., Chapman-Fredricks, J., Blonska, M., Bernal-Mizrachi, L., Alderuccio, J. P., Lossos, I., Landgraf, R. & Vega, F., Nov 1 2018, In : Cancer Letters. 436, p. 149-158 10 p.

Research output: Contribution to journalArticle

Target-based screening against eIF4A1 reveals the marine natural product elatol as a novel inhibitor of translation initiation with in vivo antitumor activity

Peters, T. L., Tillotson, J., Yeomans, A. M., Wilmore, S., Lemm, E., Jimenez-Romero, C., Amador, L. A., Li, L., Amin, A. D., Pongtornpipat, P., Zerio, C. J., Ambrose, A. J., Paine-Murrieta, G., Greninger, P., Vega, F., Benes, C. H., Packham, G., Rodríguez, A. D., Chapman, E. & Schatz, J. H., Sep 1 2018, In : Clinical Cancer Research. 24, 17, p. 4256-4270 15 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

A case of AML characterized by a novel t(4;15)(q31;q22) translocation that confers a growth-stimulatory response to retinoid-based therapy

Watts, J., Perez, A., Pereira, L., Fan, Y-S., Brown, G., Vega, F., Petrie, K., Swords, R. T. & Zelent, A. Z., Jul 11 2017, In : International Journal of Molecular Sciences. 18, 7, 1492.

Research output: Contribution to journalArticle

1 Scopus citations

Anti-CD20-interleukin-21 fusokine targets malignant B cells via direct apoptosis and NK-cell–dependent cytotoxicity

Bhatt, S., Parvin, S., Zhang, Y., Cho, H. M., Kunkalla, K., Vega, F., Timmerman, J. M., Shin, S-U., Rosenblatt, J. D. & Lossos, I., Apr 20 2017, In : Blood. 129, 16, p. 2246-2256 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Clusters of paracortical plasmacytoid dendritic cells in lupus lymphadenitis

Villada, G. & Vega, F., Mar 30 2017, In : Blood. 129, 13, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Decreased survival in hepatitis C patients with monomorphic post-transplant lymphoproliferative disorder after liver transplantation treated with frontline immunochemotherapy

Alderuccio, J. P., Stefanovic, A., Dammrich, D., Chapman-Fredricks, J., Vega, F., Selvaggi, G., Tzakis, A. & Lossos, I., Dec 19 2017, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-9 9 p.

Research output: Contribution to journalArticle

Epstein-Barr virus-positive follicular lymphoma

Mackrides, N., Campuzano-Zuluaga, G., Maque-Acosta, Y., Moul, A., Hijazi, N., Ikpatt, O., Levy, R., Verdun, R. E., Kunkalla, K., Natkunam, Y., Lossos, I., Vega, F. & Chapman-Fredricks, J., Apr 1 2017, In : Modern Pathology. 30, 4, p. 519-529 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Hepatosplenic T-cell lymphoma associated with membranoproliferative glomerulonephritis

Wu, S. C., Chapman-Fredricks, J., Vega, F., Abrahams, N., Lossos, I. & Alderuccio, J. P., Mar 28 2017, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-4 4 p.

Research output: Contribution to journalArticle

Incidental brown adipose tissue in bone marrow biopsy

Chapman-Fredricks, J. & Vega, F., Aug 17 2017, In : Blood. 130, 7, 1 p.

Research output: Contribution to journalArticle

Long-term course of patients with primary ocular adnexal MALT lymphoma: a large single-institution cohort study

Desai, A., Joag, M. G., Lekakis, L., Chapman-Fredricks, J., Vega, F., Tibshirani, R., Tse, D., Markoe, A. & Lossos, I., Jan 19 2017, In : Blood. 129, 3, p. 324-332 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2016

Active IKKb promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma

Agarwal, N. K., Kim, C. H., Kunkalla, K., Konno, H., Tjendra, Y., Kwon, D., Blonska, M., Kozloski, G. A., Moy, V. T., Verdun, R. E., Barber, G. N., Lossos, I. & Vega, F., Feb 4 2016, In : Blood. 127, 5, p. 605-615 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Characteristics and outcomes of lymphoblastic lymphoma – the University of Miami experience

Alderuccio, J. P., Amarapurkar, P., Chapman-Fredricks, J., Vega, F. & Lossos, I., Jun 1 2016, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-4 4 p.

Research output: Contribution to journalArticle

Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice

Gil, V. S., Bhagat, G., Howell, L., Zhang, J., Kim, C. H., Stengel, S., Vega, F., Zelent, A. Z. & Petrie, K., Dec 1 2016, In : DMM Disease Models and Mechanisms. 9, 12, p. 1483-1495 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Marginal zone dural lymphoma: the Memorial Sloan Kettering Cancer Center and University of Miami experiences

De La Fuente, M. I., Haggiagi, A., Moul, A., Young, R. J., Sidani, C., Markoe, A., Vega, F., DeAngelis, L. M. & Lossos, I., Sep 20 2016, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-7 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

MiR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis

Kozloski, G. A., Jiang, X., Bhatt, S., Ruiz, J., Vega, F., Shaknovich, R., Melnick, A. & Lossos, I., Jun 9 2016, In : Blood. 127, 23, p. 2856-2866 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Primary mediastinal large B-Cell lymphoma with translocations involving BCL6 and MYC (Double-Hit Lymphoma)

Campuzano-Zuluaga, G., Ortiz, D., Peng, J. H., Ikpatt, O., Fan, Y-S., Barredo, J., Vega, F. & Chapman-Fredricks, J., May 1 2016, In : American Journal of Clinical Pathology. 145, 5, p. 710-716 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Prognostic factors of hepatosplenic T-cell lymphoma clinicopathologic study of 28 cases

Yabe, M., Medeiros, L. J., Tang, G., Wang, S. A., Ahmed, S., Nieto, Y., Hu, S., Bhagat, G., Oki, Y., Patel, K. P., Routbort, M., Luthra, R., Fanale, M. A., Bueso-Ramos, C. E., Jorgensen, J. L., Vega, F., Chen, W., Hoehn, D., Konoplev, S., Milton, D. R. & 5 others, Wistuba, I., Li, S., You, M. J., Young, K. H. & Miranda, R. N., 2016, In : American Journal of Surgical Pathology. 40, 5, p. 676-688 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Routine interim disease assessment in patients undergoing induction chemotherapy for acute myeloid leukemia: Can we do better?

Campuzano-Zuluaga, G., Deutsch, Y., Salzberg, M., Gomez, A., Vargas, F., Elias, R., Kwon, D., Goodman, M., Ikpatt, O., Chapman-Fredricks, J., Watts, J., Vega, F. & Swords, R. T., 2016, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

6 Scopus citations

UNG protects B cells from AID-induced telomere loss

Cortizas, E. M., Zahn, A., Safavi, S., Reed, J. A., Vega, F., Di Noia, J. M. & Verdun, R. E., Oct 17 2016, In : The Journal of experimental medicine. 213, 11, p. 2459-2472 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

Chlamydophila psittaci-negative ocular adnexal marginal zone lymphomas express self polyreactive B-cell receptors

Zhu, D., Bhatt, S., Lu, X., Guo, F., Veelken, H., Hsu, D. K., Liu, F. T., Alvarez Cubela, S., Kunkalla, K., Vega, F., Chapman-Fredricks, J. & Lossos, I., Jul 13 2015, In : Leukemia. 29, 7, p. 1587-1599 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Gene expression analysis of plasmablastic lymphoma identifies downregulation of B-cell receptor signaling and additional unique transcriptional programs

Chapman-Fredricks, J., Gentles, A. J., Sujoy, V., Vega, F., Dumur, C. I., Blevins, T. L., Bernal-Mizrachi, L., Mosunjac, M., Pimentel, A., Zhu, D. & Lossos, I., Nov 1 2015, In : Leukemia. 29, 11, p. 2270-2273 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

Hematolymphoid neoplasms associated with rearrangements of PDGFRA, PDGFRB, and FGFR1

Vega, F., Medeiros, L. J., Bueso-Ramos, C. E., Arboleda, P. & Miranda, R. N., Sep 1 2015, In : American Journal of Clinical Pathology. 144, 3, p. 377-392 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

Introduction to the 2013 workshop of the society for hematopathology/european association for haematopathology

Ramos, C. E. B., Medeiros, L. J. & Vega, F., Jul 1 2015, In : American Journal of Clinical Pathology. 144, 1, p. 4-5 2 p.

Research output: Contribution to journalArticle

Jun-regulated genes promote interaction of diffuse large B-cell lymphoma with the microenvironment

Blonska, M., Zhu, Y., Chuang, H. H., You, M. J., Kunkalla, K., Vega, F. & Lin, X., Feb 5 2015, In : Blood. 125, 6, p. 981-991 11 p.

Research output: Contribution to journalArticle

30 Scopus citations