Feng-Chun Yang


  • 4952 Citations
1993 …2023

Research output per year

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Research Output


TET2 Loss Dysregulates the Behavior of Bone Marrow Mesenchymal Stromal Cells and Accelerates Tet2−/−-Driven Myeloid Malignancy Progression

Li, R., Zhou, Y., Cao, Z., Liu, L., Wang, J., Chen, Z., Xing, W., Chen, S., Bai, J., Yuan, W., Cheng, T., Xu, M., Yang, F-C. & Zhao, Z., Jan 1 2018, In : Stem Cell Reports. 10, 1, p. 166-179 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells

Pan, F., Wingo, T. S., Zhao, Z., Gao, R., Makishima, H., Qu, G., Lin, L., Yu, M., Ortega, J. R., Wang, J., Nazha, A., Chen, L., Yao, B., Liu, C., Chen, S., Weeks, O., Ni, H., Phillips, B. L., Huang, S., Wang, J. & 8 others, He, C., Li, G. M., Radivoyevitch, T., Aifantis, I., MacIejewski, J. P., Yang, F-C., Jin, P. & Xu, M., Jan 1 2017, In : Nature Communications. 8, 15102.

Research output: Contribution to journalArticle

31 Scopus citations

Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)

Chu, Y., Zhao, Z., Sant, D. W., Zhu, G., Greenblatt, S. M., Liu, L., Wang, J., Cao, Z., Tho, J. C., Chen, S., Liu, X., Zhang, P., Maciejewski, J. P., Nimer, S. D., Wang, G., Yuan, W., Yang, F-C. & Xu, M., Jan 1 2018, (Accepted/In press) In : Genomics, Proteomics and Bioinformatics.

Research output: Contribution to journalArticle

5 Scopus citations

The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1

Wu, X., Chen, S., He, Y., Rhodes, S. D., Mohammad, K. S., Li, X., Yang, X., Jiang, L., Nalepa, G., Snider, P., Robling, A. G., Clapp, D. W., Conway, S. J., Guise, T. A. & Yang, F. C., Sep 29 2011, In : PloS one. 6, 9, e24917.

Research output: Contribution to journalArticle

22 Scopus citations

The musculoskeletal phenotype of the RASopathies

Stevenson, D. A. & Yang, F. C., May 15 2011, In : American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 157, 2, p. 90-103 14 p.

Research output: Contribution to journalArticle

29 Scopus citations

The p85α subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration

Munugalavadla, V., Vemula, S., Sims, E. C., Krishnan, S., Chen, S., Yan, J., Li, H., Niziolek, P. J., Takemoto, C., Robling, A. G., Yang, F. C. & Kapur, R., Dec 1 2008, In : Molecular and cellular biology. 28, 23, p. 7182-7198 17 p.

Research output: Contribution to journalArticle

28 Scopus citations

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes

Croker, B. A., Tarlinton, D. M., Cluse, L. A., Tuxen, A. J., Light, A., Yang, F. C., Williams, D. A. & Roberts, A. W., Apr 1 2002, In : Journal of Immunology. 168, 7, p. 3376-3386 11 p.

Research output: Contribution to journalArticle

Open Access
91 Scopus citations

Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia

Li, Y., Zhang, M., Sheng, M., Zhang, P., Chen, Z., Xing, W., Bai, J., Cheng, T., Yang, F-C. & Zhou, Y., Mar 28 2018, (Accepted/In press) In : Journal of Cancer Research and Clinical Oncology. p. 1-13 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

The TET2 interactors and their links to hematological malignancies

Pan, F., Weeks, O., Yang, F-C. & Xu, M., Jun 1 2015, In : IUBMB Life. 67, 6, p. 438-445 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

The tumor suppressor CDKN3 controls mitosis

Nalepa, G., Barnholtz-Sloan, J., Enzor, R., Dey, D., He, Y., Gehlhausen, J. R., Lehmann, A. S., Park, S. J., Yang, Y., Yang, X., Chen, S., Guan, X., Chen, Y., Renbarger, J., Yang, F. C., Parada, L. F. & Clapp, W., Jun 1 2013, In : Journal of Cell Biology. 201, 7, p. 997-1012 16 p.

Research output: Contribution to journalArticle

43 Scopus citations

Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion

Si, X., Zhang, X., Hao, X., Li, Y., Chen, Z., Ding, Y., Shi, H., Bai, J., Gao, Y., Cheng, T., Yang, F-C. & Zhou, Y., 2016, In : Oncotarget. 7, 47, p. 78095-78109 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Whole exome sequencing reveals concomitant mutations of multiple FA genes in individual Fanconi anemia patients

Chang, L., Yuan, W., Zeng, H., Zhou, Q., Wei, W., Zhou, J., Li, M., Wang, X., Xu, M., Yang, F., Yang, Y., Cheng, T. & Zhu, X., May 15 2014, In : BMC Medical Genomics. 7, 1, 24.

Research output: Contribution to journalArticle

6 Scopus citations