Feng-Chun Yang

Professor

  • 4952 Citations
1993 …2023

Research output per year

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Research Output

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Article
2001

Biochemical and Biological Characterization of a Human Rac2 GTPase Mutant Associated with Phagocytic Immunodeficiency

Gu, Y., Jia, B., Yang, F-C., D'Souza, M., Harris, C. E., Derrow, C. W., Zheng, Y. & Williams, D. A., May 11 2001, In : Journal of Biological Chemistry. 276, 19, p. 15929-15938 10 p.

Research output: Contribution to journalArticle

72 Scopus citations

Evidence for the presence of murine primitive megakarycytopoiesis in the early yolk sac

Xu, M., Matsuoka, S., Yang, F-C., Ebihara, Y., Manabe, A., Tanaka, R., Eguchi, M., Asano, S., Nakahata, T. & Tsuji, K., Apr 1 2001, In : Blood. 97, 7, p. 2016-2022 7 p.

Research output: Contribution to journalArticle

74 Scopus citations

Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization

Yang, F-C., Atkinson, S. J., Gu, Y., Borneo, J. B., Roberts, A. W., Zheng, Y., Pennington, J. & Williams, D. A., May 8 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 10, p. 5614-5618 5 p.

Research output: Contribution to journalArticle

148 Scopus citations
2000

Cytokine requirement for the development of T-lymphoid lineage potential in clonal lymphohaematopoietic progenitors in vitro

Ma, F., Yang, F-C., Kaneko, A., Manabe, A., Tanaka, R., Asano, S., Nakahata, T. & Tsuji, K., 2000, In : British Journal of Haematology. 111, 4, p. 1170-1179 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency

Williams, D. A., Tao, W., Yang, F-C., Kim, C., Gu, Y., Mansfield, P., Levine, J. E., Petryniak, B., Derrow, C. W., Harris, C., Jia, B., Zheng, Y., Ambruso, D. R., Lowe, J. B., Atkinson, S. J., Dinauer, M. C. & Boxer, L., Sep 1 2000, In : Blood. 96, 5, p. 1646-1654 9 p.

Research output: Contribution to journalArticle

262 Scopus citations

Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo

Ingram, D. A., Yang, F-C., Travers, J. B., Wenning, M. J., Hiatt, K., New, S., Hood, A., Shannon, K., Williams, D. A. & Clapp, D. W., Jan 3 2000, In : Journal of Experimental Medicine. 191, 1, p. 181-187 7 p.

Research output: Contribution to journalArticle

146 Scopus citations

Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells

Yang, F-C., Kapur, R., King, A. J., Tao, W., Kim, C., Borneo, J., Breese, R., Marshall, M., Dinauer, M. C. & Williams, D. A., 2000, In : Immunity. 12, 5, p. 557-568 12 p.

Research output: Contribution to journalArticle

138 Scopus citations
1999

Differential effects of human granulocyte colony-stimulating factor (hG- CSF) and thrombopoietin on megakaryopoiesis and platelet function in hG-CSF receptor-transgenic mice

Yang, F-C., Tsuji, K., Oda, A., Ebihara, Y., Xu, M., Kaneko, A., Hanada, S., Mitsui, T., Kikuchi, A., Manabe, A., Watanabe, S., Ikeda, Y. & Nakahata, T., Aug 1 1999, In : Blood. 94, 3, p. 950-958 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
1998

Human granulocyte colony-stimulating factor (G-CSF) stimulates the in vitro and in vivo development but not commitment of primitive multipotential progenitors from transgenic mice expressing the human G-CSF receptor

Yang, F-C., Watanabe, S., Tsuji, K., Xu, M., Kaneko, A., Ebihara, Y. & Nakahata, T., Dec 15 1998, In : Blood. 92, 12, p. 4632-4640 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines

Xu, M., Tsuji, K., Ueda, T., Mukouyama, Y. S., Hara, T., Yang, F-C., Ebihara, Y., Matsuoka, S., Manabe, A., Kikuchi, A., Ito, M., Miyajima, A. & Nakahata, T., Sep 15 1998, In : Blood. 92, 6, p. 2032-2040 9 p.

Research output: Contribution to journalArticle

131 Scopus citations
1997

Analysis of hemopoietic stem cell proliferation and differentiation using hg-csf receptor transgenic mice

Yang, F-C., Watanabeü, S., Ebihara, Y., Azusa Kaneko Mmg-Jiang, X. U., Kohichiro, T. S. U. J. I. & Nakahata, T., 1997, In : Experimental Hematology. 25, 8, p. 839 1 p.

Research output: Contribution to journalArticle

B cell subpopulations separated by CD27 and crucial collaboration of CD27 + B cells and helper T cells in immunoglobulin production

Agematsu, K., Nagumo, H., Yang, F-C., Nakazawa, T., Fukushima, K., Ito, S., Sugita, K., Mori, T., Kobata, T., Morimoto, C. & Komiyama, A., Aug 1997, In : European Journal of Immunology. 27, 8, p. 2073-2079 7 p.

Research output: Contribution to journalArticle

229 Scopus citations

Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells

Umemoto, Y., Tsuji, K., Yang, F-C., Ebihara, Y., Kaneko, A., Furukawa, S. & Nakahata, T., 1997, In : Blood. 90, 9, p. 3438-3443 6 p.

Research output: Contribution to journalArticle

148 Scopus citations
1996

A killing defect of natural killer cells as an underlying immunologic abnormality in childhood systemic lupus erythematosus

Yabuhara, A., Yang, F-C., Nakazawa, T., Iwasaki, Y., Mori, T., Koike, K., Kawai, H. & Komiyama, A., 1996, In : Journal of Rheumatology. 23, 1, p. 171-177 7 p.

Research output: Contribution to journalArticle

63 Scopus citations

CD27/CD70 interaction directly induces natural killer cell killing activity

Yang, F-C., Agematsu, K., Nakazawa, T., Mori, T., Ito, S., Kobata, T., Morimoto, C. & Komiyama, A., 1996, In : Immunology. 88, 2, p. 289-293 5 p.

Research output: Contribution to journalArticle

53 Scopus citations
1995

CD27/CD70 interaction directly drives B cell IgG and IgM synthesis

Agematsu, K., Kobata, T., Yang, F-C., Nakazawa, T., Fukushima, K., Kitahara, M., Mori, T., Sugita, K., Morimoto, C. & Komiyama, A., Oct 1995, In : European Journal of Immunology. 25, 10, p. 2825-2829 5 p.

Research output: Contribution to journalArticle

75 Scopus citations

Frequent natural killer cell abnormality in children in an area highly contaminated by the Chernobyl accident

Koike, K., Yabuhara, A., Yang, F-C., Shiohara, M., Sawai, N., Sugenoya, A., Iida, F., Koyama, Y., Takano, K., Takahashi, T., Kamata, M., Koizumi, Y., Anatoliebna, A. T., Skidanenko, G. I. & Komiyama, A., Apr 1995, In : International Journal of Hematology. 61, 3, p. 139-145 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Functional abnormalities of natural killer cells in childhood hemophagocytic syndrome

Yang, F-C., Yabuhara, A., Koike, K. & Komiyama, A., Feb 1995, In : Nihon Rinsho Men"eki Gakkai kaishi = Japanese journal of clinical immunology. 18, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

1994
2 Scopus citations
1993

Hemophagocytic syndrome with high level of interferon-gamma in the advanced stage

Shiohara, M., Koike, K., Sawai, N., Kasai, S., Yang, F-C., Yabuhara, A., Nakahata, T. & Komiyama, A., Dec 1993, In : [Rinsho ketsueki] The Japanese journal of clinical hematology. 34, 12, p. 1573-1578 6 p.

Research output: Contribution to journalArticle

3 Scopus citations