Feng-Chun Yang

Professor

  • 4952 Citations
1993 …2023

Research output per year

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Research Output

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Article

Ras dependent paracrine secretion of osteopontin by nf1 +/- osteoblasts promote osteodast activation in a neurofibromatosis type i murine model

Li, H., Liu, Y., Zhang, Q., Jing, Y., Chen, S., Song, Z., Yan, J., Li, Y., Wu, X., Zhang, X., Zhang, Y., Case, J., Yu, M., Ingram, D. A. & Yang, F-C., Jun 2009, In : Pediatric Research. 65, 6, p. 613-618 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo

Guo, Y., Yang, H., Chen, S., Zhang, P., Li, R., Nimer, S. D., William Harbour, J., Xu, M. & Yang, F-C., Apr 2 2018, (Accepted/In press) In : Leukemia. p. 1-4 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Skeletal abnormalities in neurofibromatosis type 1: Approaches to therapeutic options

Elefteriou, F., Kolanczyk, M., Schindeler, A., Viskochil, D. H., Hock, J. M., Schorry, E. K., Crawford, A. H., Friedman, J. M., Little, D., Peltonen, J., Carey, J. C., Feldman, D., Yu, X., Armstrong, L., Birch, P., Kendler, D. L., Mundlos, S., Yang, F-C., Agiostratidou, G., Hunter-Schaedle, K. & 1 others, Stevenson, D. A., Oct 2009, In : American Journal of Medical Genetics, Part A. 149, 10, p. 2327-2338 12 p.

Research output: Contribution to journalArticle

79 Scopus citations

Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines

Xu, M., Tsuji, K., Ueda, T., Mukouyama, Y. S., Hara, T., Yang, F-C., Ebihara, Y., Matsuoka, S., Manabe, A., Kikuchi, A., Ito, M., Miyajima, A. & Nakahata, T., Sep 15 1998, In : Blood. 92, 6, p. 2032-2040 9 p.

Research output: Contribution to journalArticle

131 Scopus citations

TET1 plays an essential oncogenic role in MLL-rearranged leukemia

Huang, H., Jiang, X., Li, Z., Li, Y., Song, C. X., He, C., Sun, M., Chen, P., Gurbuxani, S., Wang, J., Hong, G. M., Elkahloun, A. G., Arnovitz, S., Wang, J., Szulwach, K., Lin, L., Street, C., Wunderlich, M., Dawlaty, M., Neilly, M. B. & 9 others, Jaenisch, R., Yang, F-C., Mulloy, J. C., Jin, P., Liu, P. P., Rowley, J. D., Xu, M., He, C. & Chen, J., Jul 16 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 29, p. 11994-11999 6 p.

Research output: Contribution to journalArticle

113 Scopus citations

TET2 Loss Dysregulates the Behavior of Bone Marrow Mesenchymal Stromal Cells and Accelerates Tet2−/−-Driven Myeloid Malignancy Progression

Li, R., Zhou, Y., Cao, Z., Liu, L., Wang, J., Chen, Z., Xing, W., Chen, S., Bai, J., Yuan, W., Cheng, T., Xu, M., Yang, F-C. & Zhao, Z., Jan 1 2018, In : Stem Cell Reports. 10, 1, p. 166-179 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells

Pan, F., Wingo, T. S., Zhao, Z., Gao, R., Makishima, H., Qu, G., Lin, L., Yu, M., Ortega, J. R., Wang, J., Nazha, A., Chen, L., Yao, B., Liu, C., Chen, S., Weeks, O., Ni, H., Phillips, B. L., Huang, S., Wang, J. & 8 others, He, C., Li, G. M., Radivoyevitch, T., Aifantis, I., MacIejewski, J. P., Yang, F-C., Jin, P. & Xu, M., Jan 1 2017, In : Nature Communications. 8, 15102.

Research output: Contribution to journalArticle

31 Scopus citations

Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)

Chu, Y., Zhao, Z., Sant, D. W., Zhu, G., Greenblatt, S. M., Liu, L., Wang, J., Cao, Z., Tho, J. C., Chen, S., Liu, X., Zhang, P., Maciejewski, J. P., Nimer, S. D., Wang, G., Yuan, W., Yang, F-C. & Xu, M., Jan 1 2018, (Accepted/In press) In : Genomics, Proteomics and Bioinformatics.

Research output: Contribution to journalArticle

5 Scopus citations

The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1

Wu, X., Chen, S., He, Y., Rhodes, S. D., Mohammad, K. S., Li, X., Yang, X., Jiang, L., Nalepa, G., Snider, P., Robling, A. G., Clapp, D. W., Conway, S. J., Guise, T. A. & Yang, F-C., Sep 29 2011, In : PLoS One. 6, 9, e24917.

Research output: Contribution to journalArticle

22 Scopus citations

The musculoskeletal phenotype of the RASopathies

Stevenson, D. A. & Yang, F-C., May 15 2011, In : American Journal of Medical Genetics, Part A. 157, 2, p. 90-103 14 p.

Research output: Contribution to journalArticle

29 Scopus citations

The p85α subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration

Munugalavadla, V., Vemula, S., Sims, E. C., Krishnan, S., Chen, S., Yan, J., Li, H., Niziolek, P. J., Takemoto, C., Robling, A. G., Yang, F-C. & Kapur, R., Dec 2008, In : Molecular and Cellular Biology. 28, 23, p. 7182-7198 17 p.

Research output: Contribution to journalArticle

28 Scopus citations

The Plexiform Neurofibroma Microenvironment

Yang, F-C., Staser, K. & Clapp, D. W., 2012, (Accepted/In press) In : Cancer Microenvironment. p. 1-4 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes

Croker, B. A., Tarlinton, D. M., Cluse, L. A., Tuxen, A. J., Light, A., Yang, F-C., Williams, D. A. & Roberts, A. W., Apr 1 2002, In : Journal of Immunology. 168, 7, p. 3376-3386 11 p.

Research output: Contribution to journalArticle

91 Scopus citations

Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia

Li, Y., Zhang, M., Sheng, M., Zhang, P., Chen, Z., Xing, W., Bai, J., Cheng, T., Yang, F-C. & Zhou, Y., Mar 28 2018, (Accepted/In press) In : Journal of Cancer Research and Clinical Oncology. p. 1-13 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

The TET2 interactors and their links to hematological malignancies

Pan, F., Weeks, O., Yang, F-C. & Xu, M., Jun 1 2015, In : IUBMB Life. 67, 6, p. 438-445 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

The tumor suppressor CDKN3 controls mitosis

Nalepa, G., Barnholtz-Sloan, J., Enzor, R., Dey, D., He, Y., Gehlhausen, J. R., Lehmann, A. S., Park, S. J., Yang, Y., Yang, X., Chen, S., Guan, X., Chen, Y., Renbarger, J., Yang, F-C., Parada, L. F. & Clapp, W., Jun 2013, In : Journal of Cell Biology. 201, 7, p. 997-1012 16 p.

Research output: Contribution to journalArticle

43 Scopus citations

Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion

Si, X., Zhang, X., Hao, X., Li, Y., Chen, Z., Ding, Y., Shi, H., Bai, J., Gao, Y., Cheng, T., Yang, F-C. & Zhou, Y., 2016, In : Oncotarget. 7, 47, p. 78095-78109 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Whole exome sequencing reveals concomitant mutations of multiple FA genes in individual Fanconi anemia patients

Chang, L., Yuan, W., Zeng, H., Zhou, Q., Wei, W., Zhou, J., Li, M., Wang, X., Xu, M., Yang, F-C., Yang, Y., Cheng, T. & Zhu, X., May 15 2014, In : BMC Medical Genomics. 7, 1, 24.

Research output: Contribution to journalArticle

6 Scopus citations