Feng-Chun Yang

Professor

  • 4907 Citations
1993 …2023
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Research Output 1993 2019

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Article
6 Citations (Scopus)
Mesenchymal Stromal Cells
Bone Marrow
Density Gradient Centrifugation
Chondrocytes
Centrifugation
1 Citation (Scopus)

Aberrant Myeloid Differentiation Contributes to the Development of Osteoporosis in Neurofibromatosis Type 1

Rhodes, S. D. & Yang, F-C., Feb 1 2016, In : Current Osteoporosis Reports. 14, 1, p. 10-15 6 p.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Osteoporosis
Neurofibromin 1
Metabolic Bone Diseases
Osteoclasts
2 Citations (Scopus)
Recycling
Natural Killer Cells
Interferons
Interleukin-2
Infectious Mononucleosis
63 Citations (Scopus)

A killing defect of natural killer cells as an underlying immunologic abnormality in childhood systemic lupus erythematosus

Yabuhara, A., Yang, F-C., Nakazawa, T., Iwasaki, Y., Mori, T., Koike, K., Kawai, H. & Komiyama, A., 1996, In : Journal of Rheumatology. 23, 1, p. 171-177 7 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Systemic Lupus Erythematosus
Juvenile Arthritis
Recycling
Lymphocyte Subsets
1 Citation (Scopus)

Alteration in the cytokine secretion of bone marrow stromal cells from patients with chronic myelomonocytic leukemia contribute to impaired hematopoietic supportive activity

Shi, H., Wang, Y., Li, R., Xing, W., Yang, F-C., Bai, J. & Zhou, Y., Jan 1 2018, In : Stem Cells International. 2018, 5921392.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Mesenchymal Stromal Cells
Cytokines
Fetal Blood
Blood Cells
22 Citations (Scopus)

Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow

Lim, M., Pang, Y., Ma, S., Hao, S., Shi, H., Zheng, Y., Hua, C., Gu, X., Yang, F-C., Yuan, W. & Cheng, T., Jan 1 2016, In : Leukemia. 30, 1, p. 154-162 9 p.

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Hematopoietic Stem Cells
Mesenchymal Stromal Cells
Bone Marrow
Hematopoietic System
27 Citations (Scopus)

AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice

Pulliam, A. C., Hobson, M. J., Ciccone, S. L., Li, Y., Chen, S., Srour, E. F., Yang, F-C., Broxmeyer, H. E. & Clapp, D. W., Sep 2008, In : Experimental Hematology. 36, 9, p. 1084-1090 7 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Granulocyte Colony-Stimulating Factor
Knockout Mice
Stem Cells
Bone Marrow
29 Citations (Scopus)

A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation

Gehlhausen, J. R., Park, S. J., Hickox, A. E., Shew, M., Staser, K., Rhodes, S. D., Menon, K., Lajiness, J. D., Mwanthi, M., Yang, X., Yuan, J., Territo, P., Hutchins, G., Nalepa, G., Yang, F-C., Conway, S. J., Heinz, M. G., Stemmer-Rachamimov, A., Yates, C. W. & Clapp, D. W., Jan 1 2015, In : Human Molecular Genetics. 24, 1, p. 1-8 8 p., ddu414.

Research output: Contribution to journalArticle

Neurofibromatosis 2
Neurilemmoma
Vestibulocochlear Nerve
Neurofibromatosis 2 Genes
Cranial Nerves
14 Citations (Scopus)

An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in fanconi anemia

Zhou, Y., He, Y., Xing, W., Zhang, P., Shi, H., Chen, S., Shi, J., Bai, J., Rhodes, S. D., Zhang, F., Yuan, J., Yang, X., Zhu, X., Li, Y., Hanenberg, H., Xu, M., Robertson, K. A., Yuan, W., Nalepa, G., Cheng, T. & 2 others, Clapp, D. W. & Yang, F-C., 2017, In : Haematologica. 102, 6, p. 1017-1027 11 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Mesenchymal Stromal Cells
Bone Marrow
Inborn Genetic Diseases
Hematopoietic Stem Cells

Analysis of hemopoietic stem cell proliferation and differentiation using hg-csf receptor transgenic mice

Yang, F-C., Watanabeü, S., Ebihara, Y., Azusa Kaneko Mmg-Jiang, X. U., Kohichiro, T. S. U. J. I. & Nakahata, T., 1997, In : Experimental Hematology. 25, 8, p. 839 1 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor Receptors
Transgenic Mice
Cell Differentiation
Stem Cells
Cell Proliferation
9 Citations (Scopus)

A novel ASXL1–OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies

Inoue, D., Fujino, T., Sheridan, P., Zhang, Y. Z., Nagase, R., Horikawa, S., Li, Z., Matsui, H., Kanai, A., Saika, M., Yamaguchi, R., Kozuka-Hata, H., Kawabata, K. C., Yokoyama, A., Goyama, S., Inaba, T., Imoto, S., Miyano, S., Xu, M., Yang, F-C. & 2 others, Oyama, M. & Kitamura, T., Mar 3 2018, (Accepted/In press) In : Leukemia. p. 1-11 11 p.

Research output: Contribution to journalArticle

Methylation
Transcriptional Activation
Neoplasms
Histone Code
Proteins

Anti-mouse CD122 antibody promotes the hematopoietic repopulating capacity of cord blood CD34⁺ cells in NOD/SCID mice

Sheng, M. Y., Shi, H., Xing, W., Wang, W. J., Si, X. H., Bai, J., Yuan, W. P., Zhou, Y. & Yang, F-C., Dec 1 2014, In : Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology. 22, 6, p. 1673-1677 5 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Fetal Blood
Blood Cells
Antibodies
Natural Killer Cells
18 Citations (Scopus)

A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells

Staser, K., Shew, M. A., Michels, E. G., Mwanthi, M. M., Yang, F-C., Clapp, D. W. & Park, S. J., Jan 2013, In : Experimental Hematology. 41, 1

Research output: Contribution to journalArticle

p21-Activated Kinases
Protein Phosphatase 2
Mast Cells
Actins
Cell Degranulation
31 Citations (Scopus)

Approaches to treating NF1 tibial pseudarthrosis: Consensus from the children's tumor foundation NF1 bone abnormalities consortium

Stevenson, D. A., Little, D., Armstrong, L., Crawford, A. H., Eastwood, D., Friedman, J. M., Greggi, T., Gutierrez, G., Hunter-Schaedle, K., Kendler, D. L., Kolanczyk, M., Monsell, F., Oetgen, M., Richards, B. S., Schindeler, A., Schorry, E. K., Wilkes, D., Viskochil, D. H., Yang, F-C. & Elefteriou, F., Apr 2013, In : Journal of Pediatric Orthopaedics. 33, 3, p. 269-275 7 p.

Research output: Contribution to journalArticle

Pseudarthrosis
Neurofibromatosis 1
Consensus
Bone and Bones
Neoplasms
3 Citations (Scopus)

ASXL1 alteration cooperates with JAK2V617F to accelerate myelofibrosis

Guo, Y., Zhou, Y., Yamatomo, S., Yang, H., Zhang, P., Chen, S., Nimer, S. D., Zhao, Z. J., Xu, M., Bai, J. & Yang, F-C., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Primary Myelofibrosis
13 Citations (Scopus)

ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis

Li, Z., Zhang, P., Yan, A., Guo, Z., Ban, Y., Li, J., Chen, S., Yang, H., He, Y., Li, J., Guo, Y., Zhang, W., Hajiramezanali, E., An, H., Fajardo, D., William Harbour, J., Ruan, Y., Nimer, S. D., Yu, P., Chen, X. & 2 others, Xu, M. & Yang, F-C., Jan 1 2017, In : Science advances. 3, 1, e1601602.

Research output: Contribution to journalArticle

Chromatids
Hematopoiesis
Gene Expression
Telophase
Chromatin Immunoprecipitation
18 Citations (Scopus)

ASXL1 plays an important role in erythropoiesis

Shi, H., Yamamoto, S., Sheng, M., Bai, J., Zhang, P., Chen, R., Chen, S., Shi, L., Abdel-Wahab, O., Xu, M., Zhou, Y. & Yang, F-C., Jun 29 2016, In : Scientific Reports. 6, 28789.

Research output: Contribution to journalArticle

Erythropoiesis
Myelodysplastic Syndromes
Erythroblasts
Leukemia, Myelomonocytic, Chronic
Erythrocytes
228 Citations (Scopus)

B cell subpopulations separated by CD27 and crucial collaboration of CD27 + B cells and helper T cells in immunoglobulin production

Agematsu, K., Nagumo, H., Yang, F-C., Nakazawa, T., Fukushima, K., Ito, S., Sugita, K., Mori, T., Kobata, T., Morimoto, C. & Komiyama, A., Aug 1997, In : European Journal of Immunology. 27, 8, p. 2073-2079 7 p.

Research output: Contribution to journalArticle

Helper-Inducer T-Lymphocytes
Immunoglobulins
B-Lymphocytes
Immunoglobulin D
Blood Cells
72 Citations (Scopus)

Biochemical and Biological Characterization of a Human Rac2 GTPase Mutant Associated with Phagocytic Immunodeficiency

Gu, Y., Jia, B., Yang, F-C., D'Souza, M., Harris, C. E., Derrow, C. W., Zheng, Y. & Williams, D. A., May 11 2001, In : Journal of Biological Chemistry. 276, 19, p. 15929-15938 10 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Cells
Guanine Nucleotide Exchange Factors
Guanosine Triphosphate
Bone
53 Citations (Scopus)

Bone resorption in syndromes of the Ras/MAPK pathway

Stevenson, D., Schwarz, E., Carey, J., Viskochil, D., Hanson, H., Bauer, S., Cindy Weng, H. Y., Greene, T., Reinker, K., Swensen, J., Chan, R., Yang, F-C., Senbanjo, L., Yang, Z., Mao, R. & Pasquali, M., Dec 2011, In : Clinical Genetics. 80, 6, p. 566-573 8 p.

Research output: Contribution to journalArticle

Bone Resorption
Mitogen-Activated Protein Kinases
Bone and Bones
Urine
Costello Syndrome
5 Citations (Scopus)

Cardiac Sca-1+ Cells Are Not Intrinsic Stem Cells for Myocardial Development, Renewal, and Repair

Zhang, L., Sultana, N., Yan, J., Yang, F., Chen, F., Chepurko, E., Yang, F-C., Du, Q., Zangi, L., Xu, M., Bu, L. & Cai, C. L., Dec 18 2018, In : Circulation. 138, 25, p. 2919-2930 12 p.

Research output: Contribution to journalArticle

Stem Cells
Endothelial Cells
Genetic Models
Cardiac Myocytes
Population
7 Citations (Scopus)

CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathais, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schuerer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F-C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Jun 11 2018, In : Cancer Cell. 33, 6, p. 1111-1127.e5

Research output: Contribution to journalArticle

Hematopoiesis
Acute Myeloid Leukemia
Cell Cycle
Protein-Arginine N-Methyltransferases
Apoptosis
9 Citations (Scopus)

Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner

Man, N., Tan, Y., Sun, X. J., Liu, F., Cheng, G., Greenblatt, S. M., Martinez, C., Karl, D. L., Ando, K., Sun, M., Hou, D., Chen, B., Xu, M., Yang, F-C., Chen, Z., Chen, S., Nimer, S. D. & Wang, L., May 18 2017, In : Blood. 129, 20, p. 2782-2792 11 p.

Research output: Contribution to journalArticle

Autophagy
Caspase 3
Modulation
Acute Myeloid Leukemia
Leukemia
75 Citations (Scopus)

CD27/CD70 interaction directly drives B cell IgG and IgM synthesis

Agematsu, K., Kobata, T., Yang, F-C., Nakazawa, T., Fukushima, K., Kitahara, M., Mori, T., Sugita, K., Morimoto, C. & Komiyama, A., Oct 1995, In : European Journal of Immunology. 25, 10, p. 2825-2829 5 p.

Research output: Contribution to journalArticle

Immunoglobulin M
B-Lymphocytes
Immunoglobulin G
Interleukin-2
T-Lymphocytes
52 Citations (Scopus)

CD27/CD70 interaction directly induces natural killer cell killing activity

Yang, F-C., Agematsu, K., Nakazawa, T., Mori, T., Ito, S., Kobata, T., Morimoto, C. & Komiyama, A., 1996, In : Immunology. 88, 2, p. 289-293 5 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Interleukin-12
Coculture Techniques
Interleukin-2
Flow Cytometry
14 Citations (Scopus)

c-Fms Signaling Mediates Neurofibromatosis Type-1 Osteoclast Gain-In-Functions

He, Y., Rhodes, S. D., Chen, S., Wu, X., Yuan, J., Yang, X., Jiang, L., Li, X., Takahashi, N., Xu, M., Mohammad, K. S., Guise, T. A. & Yang, F-C., Nov 7 2012, In : PLoS One. 7, 11, e46900.

Research output: Contribution to journalArticle

osteoclasts
Neurofibromatosis 1
Osteoclasts
macrophage colony-stimulating factor
Macrophage Colony-Stimulating Factor
4 Citations (Scopus)

Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy

Zhang, P., He, F., Bai, J., Yamamoto, S., Chen, S., Zhang, L., Sheng, M., Zhang, L., Guo, Y., Man, N., Yang, H., Wang, S., Cheng, T., Nimer, S. D., Zhou, Y., Xu, M., Wang, Q. F. & Yang, F-C., Dec 3 2018, In : Journal of Clinical Investigation. 128, 12, p. 5383-5398 16 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Chromatin
Mutation
Hematopoietic Stem Cells
Genes
150 Citations (Scopus)

Collection, cryopreservation, and characterization of human dental pulp-derived mesenchymal stem cells for banking and clinical use

Perry, B. C., Zhou, D., Wu, X., Yang, F-C., Byers, M. A., Chu, T. M. G., Hockema, J. J., Woods, E. J. & Goebel, W. S., 2008, In : Tissue Engineering - Part C: Methods. 14, 2, p. 149-156 8 p.

Research output: Contribution to journalArticle

Dental Pulp
Cryopreservation
Stem cells
Mesenchymal Stromal Cells
Pulp
47 Citations (Scopus)

Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice

Zhao, Z., Chen, L., Dawlaty, M. M., Pan, F., Weeks, O., Zhou, Y., Cao, Z., Shi, H., Wang, J., Lin, L., Chen, S., Yuan, W., Qin, Z., Ni, H., Nimer, S. D., Yang, F-C., Jaenisch, R., Jin, P. & Xu, M., Nov 24 2015, In : Cell Reports. 13, 8, p. 1692-1704 13 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Cells
Dioxygenases
Hematologic Neoplasms
Neoplasms
34 Citations (Scopus)

Continuous in vivo infusion of interferon-gamma (IFN-γ) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg -/- mice

Si, Y., Ciccone, S., Yang, F-C., Yuan, J., Zeng, D., Chen, S., Van De Vrugt, H. J., Critser, J., Arwert, F., Haneline, L. S. & Clapp, D. W., Dec 15 2006, In : Blood. 108, 13, p. 4283-4287 5 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Interferon-gamma
Stem cells
Bone
Stem Cells
10 Citations (Scopus)

CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia

Luo, H., Wang, F., Zha, J., Li, H., Yan, B., Du, Q., Yang, F., Sobh, A., Vulpe, C., Drusbosky, L., Cogle, C., Chepelev, I., Xu, B., Nimer, S. D., Licht, J., Qiu, Y., Chen, B., Xu, M. & Huang, S., Aug 23 2018, In : Blood. 132, 8, p. 837-848 12 p.

Research output: Contribution to journalArticle

Transcription
Acute Myeloid Leukemia
Gene expression
Chromatin
Genes
15 Citations (Scopus)

Cul4A is required for hematopoietic stem-cell engraftment and self-renewal

Li, B., Jia, N., Waning, D. L., Yang, F-C., Haneline, L. S. & Chun, K. T., Oct 1 2007, In : Blood. 110, 7, p. 2704-2707 4 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Ubiquitin
Stem cells
Ligases
Proteolysis
8 Citations (Scopus)

Cytokine requirement for the development of T-lymphoid lineage potential in clonal lymphohaematopoietic progenitors in vitro

Ma, F., Yang, F-C., Kaneko, A., Manabe, A., Tanaka, R., Asano, S., Nakahata, T. & Tsuji, K., 2000, In : British Journal of Haematology. 111, 4, p. 1170-1179 10 p.

Research output: Contribution to journalArticle

Cytokines
T-Lymphocytes
Stem Cell Factor
Organ Culture Techniques
Fluorouracil
343 Citations (Scopus)

Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies

Li, Z., Cai, X., Cai, C. L., Wang, J., Zhang, W., Petersen, B. E., Yang, F-C. & Xu, M., Oct 27 2011, In : Blood. 118, 17, p. 4509-4518 10 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
5-Methylcytosine
Neoplasms
Tumors
23 Citations (Scopus)

Differential effects of human granulocyte colony-stimulating factor (hG- CSF) and thrombopoietin on megakaryopoiesis and platelet function in hG-CSF receptor-transgenic mice

Yang, F-C., Tsuji, K., Oda, A., Ebihara, Y., Xu, M., Kaneko, A., Hanada, S., Mitsui, T., Kikuchi, A., Manabe, A., Watanabe, S., Ikeda, Y. & Nakahata, T., Aug 1 1999, In : Blood. 94, 3, p. 950-958 9 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor Receptors
Thrombopoietin
Granulocyte Colony-Stimulating Factor
Platelets
Transgenic Mice
6 Citations (Scopus)

Differential role of Id1 in MLL-AF9-driven leukemia based on cell of origin

Man, N., Sun, X. J., Tan, Y., García-Cao, M., Liu, F., Cheng, G., Hatlen, M., Xu, H., Shah, R., Chastain, N., Liu, N., Huang, G., Zhou, Y., Sheng, M., Song, J., Yang, F-C., Benezra, R., Nimer, S. D. & Wang, L., 2016, In : Blood. 127, 19, p. 2322-2326 5 p.

Research output: Contribution to journalArticle

Leukemia
DNA
Liver
Bone
Bone Marrow Cells
262 Citations (Scopus)

Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency

Williams, D. A., Tao, W., Yang, F-C., Kim, C., Gu, Y., Mansfield, P., Levine, J. E., Petryniak, B., Derrow, C. W., Harris, C., Jia, B., Zheng, Y., Ambruso, D. R., Lowe, J. B., Atkinson, S. J., Dinauer, M. C. & Boxer, L., Sep 1 2000, In : Blood. 96, 5, p. 1646-1654 9 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Phagocytes
Cells
Mutation
Neutrophils
4 Citations (Scopus)

Dystrophic spinal deformities in a neurofibromatosis type 1 murine model

Rhodes, S. D., Zhang, W., Yang, D., Yang, H., Chen, S., Wu, X., Li, X., Yang, X., Mohammad, K. S., Guise, T. A., Bergner, A. L., Stevenson, D. A. & Yang, F-C., Mar 18 2015, In : PLoS One. 10, 3, e0119093.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Fusion reactions
animal models
intervertebral disks
Intervertebral Disc
20 Citations (Scopus)

Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle

Li, B., Yang, F-C., Clapp, D. W. & Chun, K. T., Mar 1 2003, In : Blood. 101, 5, p. 1769-1776 8 p.

Research output: Contribution to journalArticle

Cullin Proteins
Cell Cycle
Cells
Hematopoiesis
Myeloid Cells
53 Citations (Scopus)

Erk1 positively regulates osteoclast differentiation and bone resorptive activity

He, Y., Staser, K., Rhodes, S. D., Liu, Y., Wu, X., Park, S. J., Yuan, J., Yang, X., Li, X., Jiang, L., Chen, S. & Yang, F-C., Sep 22 2011, In : PLoS One. 6, 9, e24780.

Research output: Contribution to journalArticle

osteoclasts
Osteoclasts
Bone
bones
Bone and Bones

Erratum: Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1 (Human Molecular Genetics (2008) vol. 17(7) (936-948) 10.1093/hmg/ddm366)

Yan, J., Chen, S., Zhang, Y., Li, X., Li, Y., Wu, X., Yuan, J., Robling, A. G., Kapur, R., Chan, R. J. & Yang, F-C., Jun 15 2008, In : Human Molecular Genetics. 17, 12, p. 1876 1 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Medical Genetics
Osteoclasts
Molecular Biology
74 Citations (Scopus)

Evidence for the presence of murine primitive megakarycytopoiesis in the early yolk sac

Xu, M., Matsuoka, S., Yang, F-C., Ebihara, Y., Manabe, A., Tanaka, R., Eguchi, M., Asano, S., Nakahata, T. & Tsuji, K., Apr 1 2001, In : Blood. 97, 7, p. 2016-2022 7 p.

Research output: Contribution to journalArticle

Yolk Sac
Megakaryocytes
Platelets
Thrombopoietin
Stem Cell Factor
55 Citations (Scopus)

Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy

Li, X., Le Beau, M. M., Ciccone, S., Yang, F-C., Freie, B., Chen, S., Yuan, J., Hong, P., Orazi, A., Haneline, L. S. & Clapp, D. W., May 1 2005, In : Blood. 105, 9, p. 3465-3471 7 p.

Research output: Contribution to journalArticle

Stem cells
Cell culture
Chromosome Aberrations
Stem Cells
Apoptosis
7 Citations (Scopus)

Frequent natural killer cell abnormality in children in an area highly contaminated by the Chernobyl accident

Koike, K., Yabuhara, A., Yang, F-C., Shiohara, M., Sawai, N., Sugenoya, A., Iida, F., Koyama, Y., Takano, K., Takahashi, T., Kamata, M., Koizumi, Y., Anatoliebna, A. T., Skidanenko, G. I. & Komiyama, A., Apr 1995, In : International Journal of Hematology. 61, 3, p. 139-145 7 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Accidents
Radioisotopes
Radioactive Fallout
Republic of Belarus

Functional abnormalities of natural killer cells in childhood hemophagocytic syndrome

Yang, F-C., Yabuhara, A., Koike, K. & Komiyama, A., Feb 1995, In : Nihon Rinsho Men"eki Gakkai kaishi = Japanese journal of clinical immunology. 18, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

Hemophagocytic Lymphohistiocytosis
Natural Killer Cells
Recycling
Lymphokines
Interleukin-2
27 Citations (Scopus)

Functional p85α gene is required for normal murine fetal erythropoiesis

Huddleston, H., Tan, B., Yang, F-C., White, H., Wenning, M. J., Orazi, A., Yoder, M. C., Kapur, R. & Ingram, D. A., Jul 1 2003, In : Blood. 102, 1, p. 142-145 4 p.

Research output: Contribution to journalArticle

Erythroid Precursor Cells
Erythropoiesis
Phosphotransferases
Genes
Liver
31 Citations (Scopus)

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Yang, H., Kurtenbach, S., Guo, Y., Lohse, I., Durante, M. A., Li, J., Li, Z., Al-Ali, H., Li, L., Chen, Z., Field, M. G., Zhang, P., Chen, S., Yamamoto, S., Li, Z., Zhou, Y., Nimer, S. D., William Harbour, J., Wahlestedt, C. R., Xu, M. & 1 others, Yang, F-C., Jan 18 2018, In : Blood. 131, 3, p. 328-341 14 p.

Research output: Contribution to journalArticle

Comb and Wattles
Stem cells
Chromatin
Mass spectrometry
Neoplasms
146 Citations (Scopus)

Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo

Ingram, D. A., Yang, F-C., Travers, J. B., Wenning, M. J., Hiatt, K., New, S., Hood, A., Shannon, K., Williams, D. A. & Clapp, D. W., Jan 3 2000, In : Journal of Experimental Medicine. 191, 1, p. 181-187 7 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Neurofibromatosis 1
Melanocytes
Tumor Suppressor Genes
Mast Cells
31 Citations (Scopus)

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia

Pulliam-Leath, A. C., Ciccone, S. L., Nalepa, G., Li, X., Si, Y., Miravalle, L., Smith, D., Yuan, J., Li, J., Anur, P., Orazi, A., Vance, G. H., Yang, F-C., Hanenberg, H., Bagby, G. C. & Clapp, D. W., Oct 21 2010, In : Blood. 116, 16, p. 2915-2920 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Acute Myeloid Leukemia
Bone
Fanconi Anemia Complementation Group Proteins
Bone Marrow
1 Citation (Scopus)

Genetic disruption of the scaffolding protein, Kinase Suppressor of Ras 1 (KSR1), differentially regulates GM-CSF-stimulated hyperproliferation in hematopoietic progenitors expressing activating PTPN11 mutants D61Y and E76K

Yang, Z., Chen, M., Sitarski, S. A., Saadatzadeh, T., Yin, F., Yu, M., Yang, F-C. & Chan, R. J., Jul 2011, In : Leukemia Research. 35, 7, p. 961-964 4 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Protein Kinases
Hypersensitivity
Bone Marrow
KSR-1 protein kinase