Eugene Fu

Associate Professor of Clinical

  • 1226 Citations
19942018
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Research Output 1994 2018

  • 1226 Citations
  • 36 Article
  • 1 Chapter
2018
2 Citations (Scopus)

Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice

Zhuang, G. Z., Upadhyay, U., Tong, X., Kang, Y., Erasso, D. M., Fu, E., Sarantopoulos, K. D., Martin, E. R., Wiltshire, T., Diatchenko, L., Smith, S. B., Maixner, W. & Levitt, R. C., Apr 24 2018, (Accepted/In press) In : Gene Therapy. p. 1-15 15 p.

Research output: Contribution to journalArticle

Carbonic Anhydrases
Hyperalgesia
Nerve Growth Factor
Inositol
Genetic Therapy

Iatrogenic spinal epidural hematoma in the acute postoperative period

Rasekhi, R., Viswanath, O., Fu, E. & Cordova, C., Sep 1 2018, In : Ochsner Journal. 18, 3, p. 268-270 3 p.

Research output: Contribution to journalArticle

Spinal Epidural Hematoma
Postoperative Period
Neurologic Manifestations
Lower Extremity
Motor Evoked Potentials
2017
5 Citations (Scopus)

Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice

Levitt, R. C., Zhuang, G. Y., Kang, Y., Erasso, D. M., Upadhyay, U., Ozdemir, M., Fu, E., Sarantopoulos, K. D., Smith, S. B., Maixner, W., Diatchenko, L., Martin, E. R. & Wiltshire, T., May 25 2017, (Accepted/In press) In : Mammalian Genome. p. 1-9 9 p.

Research output: Contribution to journalArticle

Spinal Ganglia
Morphine
Analgesics
Calcium
Inositol
3 Citations (Scopus)

Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice

Fu, E., Erasso, D. M., Zhuang, G. Z., Upadhyay, U., Ozdemir, M., Wiltshire, T., Sarantopoulos, K. D., Smith, S. B., Maixner, W., Martin, E. R. & Levitt, R. C., Jan 1 2017, In : NeuroReport. 28, 18, p. 1215-1220 6 p.

Research output: Contribution to journalArticle

Spinal Ganglia
Morphine
Hot Temperature
Virion
Analgesia
2015
13 Citations (Scopus)

Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway

Zhuang, G. Z., Keeler, B., Grant, J., Bianchi, L., Fu, E., Zhang, Y. P., Erasso, D. M., Cui, J. G., Wiltshire, T., Li, Q., Hao, S., Sarantopoulos, K. D., Candiotti, K. A., Wishnek, S. M., Smith, S. B., Maixner, W., Diatchenko, L., Martin, E. R. & Levitt, R. C., Mar 3 2015, In : PLoS One. 10, 3, e0118273.

Research output: Contribution to journalArticle

Carbonic Anhydrases
carbonate dehydratase
Inositol
pain
Calcium
2012

Head injury

Fu, E., Jagid, J. & Harris, L. T., Jan 18 2012, Yao & Artusio's Anesthesiology: Problem-Oriented Patient Management: Seventh Edition. Wolters Kluwer Health Adis (ESP), p. 530-551 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Craniocerebral Trauma
5 Citations (Scopus)

Unexpected behaviour of the bispectral index (BIS) after brain injury

Theiler, L., Elf, R., Fu, E., Mendoza, C. & Fuhrman, T., Jul 1 2012, In : Anaesthesia. 67, 7, p. 799-800 2 p.

Research output: Contribution to journalArticle

Cognition Disorders
Cardiac Surgical Procedures
Brain Injuries
Anesthesia
Inflammation
2011
11 Citations (Scopus)

Glial NF-kappa B inhibition alters neuropeptide expression after sciatic nerve injury in mice

Zhang, Y. P., Fu, E., Sagen, J., Levitt, R. C., Candiotti, K. A., Bethea, J. R. & Brambilla, R., Apr 18 2011, In : Brain Research. 1385, p. 38-46 9 p.

Research output: Contribution to journalArticle

NF-kappa B
Glial Fibrillary Acidic Protein
Sciatic Nerve
Neuropeptides
Neuroglia
2010
86 Citations (Scopus)

Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury

Fu, E., Zhang, Y. P., Sagen, J., Candiotti, K. A., Morton, P. D., Liebl, D. J., Bethea, J. R. & Brambilla, R., Mar 1 2010, In : Pain. 148, 3, p. 509-518 10 p.

Research output: Contribution to journalArticle

Peripheral Nerve Injuries
NF-kappa B
Glial Fibrillary Acidic Protein
Neuroglia
Inflammation
2009
11 Citations (Scopus)

Does the systolic pressure variation change in the prone position?

Marks, R., Silverman, R., Fernandez, R., Candiotti, K. A. & Fu, E., Jul 24 2009, In : Journal of Clinical Monitoring and Computing. 23, 5, p. 279-282 4 p.

Research output: Contribution to journalArticle

Prone Position
Blood Pressure
Lung Compliance
Supine Position
Hypovolemia
2007
18 Citations (Scopus)

Transgenic glial nuclear factor-kappa B inhibition decreases formalin pain in mice

Fu, E., Zhang, Y. P., Sagen, J., Yang, Z. Q. & Bethea, J. R., May 1 2007, In : NeuroReport. 18, 7, p. 713-717 5 p.

Research output: Contribution to journalArticle

NF-kappa B
Glial Fibrillary Acidic Protein
Neuroglia
Formaldehyde
Pain
2006

Role of glial nf-κb inhibition on pain behavior after sciatic constriction nerve injury in mice

Fu, E., Zhang, Y. P., Sagen, J. & Bethea, J. R., 2006, In : Journal of Neurosurgical Anesthesiology. 18, 4, 1 p.

Research output: Contribution to journalArticle

Sciatic Nerve
Constriction
Neuroglia
Pain
Wounds and Injuries
2005
3 Citations (Scopus)

Bispectral Index® and the incidence of apnea during monitored anesthesia care

Soto, R. G., Fu, E., Smith, R. A. & Miguel, R. V., Nov 1 2005, In : Ambulatory Surgery. 12, 2, p. 81-84 4 p.

Research output: Contribution to journalArticle

Apnea
Anesthesia
Consciousness
Capnography
Incidence
38 Citations (Scopus)
Spinal Cord Compression
Methylprednisolone
Spinal Cord Injuries
Interleukin-1
Interleukin-6
39 Citations (Scopus)

Neuroprotection in brain and spinal cord trauma

Fu, E. & Tummala, R. P., Apr 1 2005, In : Current Opinion in Anaesthesiology. 18, 2, p. 181-187 7 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Brain
Wounds and Injuries
Induced Hypothermia
Minocycline
2004
134 Citations (Scopus)

Capnography accurately detects apnea during monitored anesthesia care

Soto, R. G., Fu, E., Vila, H. & Miguel, R. V., Aug 1 2004, In : Anesthesia and Analgesia. 99, 2, p. 379-382 4 p.

Research output: Contribution to journalArticle

Capnography
Apnea
Anesthesia
Electric Impedance
Thorax
220 Citations (Scopus)

Supplement oxygen impairs detection of hypoventilation by pulse oximetry

Fu, E., Downs, J. B., Schweiger, J. W., Miguel, R. V. & Smith, R. A., Nov 1 2004, In : Chest. 126, 5, p. 1552-1558 7 p.

Research output: Contribution to journalArticle

Hypoventilation
Oximetry
Oxygen
Air
Ventilation
2003
98 Citations (Scopus)

Acute pain management for patients undergoing thoracotomy

Soto, R. G. & Fu, E., Apr 1 2003, In : Annals of Thoracic Surgery. 75, 4, p. 1349-1357 9 p.

Research output: Contribution to journalArticle

Acute Pain
Thoracotomy
Pain Management
Opiate Alkaloids
Postoperative Pain
33 Citations (Scopus)

Forearm compartment syndrome from intravenous mannitol extravasation during general anesthesia

Edwards, J. J., Samuels, D. & Fu, E., Jan 1 2003, In : Anesthesia and Analgesia. 96, 1, p. 245-246 2 p.

Research output: Contribution to journalArticle

Compartment Syndromes
Mannitol
Forearm
General Anesthesia
168 Citations (Scopus)

Human umbilical cord blood stem cells infusion in spinal cord injury: Engraftment and beneficial influence on behavior

Saporta, S., Kim, J. J., Willing, A. E., Fu, E., Davis, C. D. & Sanberg, P. R., Jun 1 2003, In : Journal of Hematotherapy and Stem Cell Research. 12, 3, p. 271-278 8 p.

Research output: Contribution to journalArticle

Fetal Blood
Spinal Cord Injuries
Blood Cells
Stem Cells
Spinal Cord
8 Citations (Scopus)

The therapeutic effects of epidural intercellular adhesion molecule-1 monoclonal antibody in a rabbit model: Involvement of the intercellular adhesion molecule-1 pathway in spinal cord ischemia

Naidu, K. A., Fu, E., Sutton, E. T., Prockop, L. D. & Cantor, A., Sep 1 2003, In : Anesthesia and Analgesia. 97, 3, p. 857-862 6 p.

Research output: Contribution to journalArticle

Spinal Cord Ischemia
Therapeutic Uses
Intercellular Adhesion Molecule-1
Monoclonal Antibodies
Rabbits
2002
3 Citations (Scopus)
Inulin
Autoimmune Experimental Encephalomyelitis
Mannitol
Spinal Cord
Rabbits
2000
2 Citations (Scopus)

Preemptive analgesia with ketamine [1] (multiple letters)

Miguel, R., Fu, E. & Adam, F., Mar 8 2000, In : Anesthesia and Analgesia. 90, 3

Research output: Contribution to journalArticle

Medical Ethics
Ketamine
Analgesia
Opioid Analgesics
1998

Effects of epidural epinephrine on the spinal cord accumulation of epidural clonidine in rabbits [1] (multiple letters)

Mori, K., Kato, H., Stevens, J., Kito, K., Naidu, K. A., Fu, E. & Prockop, L. D., May 13 1998, In : Anesthesia and Analgesia. 86, 5, p. 1145-1146 2 p.

Research output: Contribution to journalArticle

Adrenergic alpha-Agonists
Clonidine
Epinephrine
Spinal Cord
Rabbits

Evidence for leukocyte infiltration, ICAM-1 expression, permeability following ischemic paraplegia: Functional blocking of ICAM-1 as a new therapeutic target

Naidu, K. A., Sutton, E. T., Fu, E. & Prockop, L. D., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

Paraplegia
Intercellular Adhesion Molecule-1
Infiltration
spinal cord
Permeability
1997
2 Citations (Scopus)

Epinephrine increases spinal cord concentrations of [3H]-clonidine hydrochloride in rabbits after epidural infusion

Fu, E., Naidu, K. A. & Prockop, L. D., Aug 1 1997, In : Anesthesia and Analgesia. 85, 2, p. 324-327 4 p.

Research output: Contribution to journalArticle

Clonidine
Epinephrine
Spinal Cord
Rabbits
Exsanguination
186 Citations (Scopus)

Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery

Fu, E., Miguel, R. & Scharf, J. E., May 22 1997, In : Anesthesia and Analgesia. 84, 5, p. 1086-1090 5 p.

Research output: Contribution to journalArticle

Narcotics
Ketamine
Morphine
Postoperative Pain
Pain
1996
10 Citations (Scopus)

Effect of type of anesthesia and lowerabdominal laparotomy in mice on the cytokine response to acute stress

Fu, E., Norman, J. G., Scharf, J. E. & Burdash, N., Dec 1 1996, In : Regional Anesthesia. 21, 5, p. 470-473 4 p.

Research output: Contribution to journalArticle

Halothane
Laparotomy
Anesthesia
Cytokines
Interleukin-6
5 Citations (Scopus)
Inulin
Mannitol
Epinephrine
Permeability
Spinal Cord
26 Citations (Scopus)

Malignant hyperthermia involving the administration of desflurane

Fu, E., Scharf, J. E., Mangar, D. & Miller, W. D., Jul 1 1996, In : Canadian Journal of Anaesthesia. 43, 7, p. 687-690 4 p.

Research output: Contribution to journalArticle

Malignant Hyperthermia
Dantrolene
Anesthesia
Acidosis
Tachycardia

The effect of preemptive fentanyl and halothane on formalin pain in mice [5]

Martin, D. C., Introna, R. P. S., Fu, E. & Scharf, J. E., May 29 1996, In : Regional Anesthesia. 21, 3, p. 274-275 2 p.

Research output: Contribution to journalArticle

Fentanyl
Halothane
Formaldehyde
Pain
1995
5 Citations (Scopus)

Effect of anesthetic technique on acute formalin-induced pain in mice

Fu, E. & Scharf, J. E., Jan 1 1995, In : Regional Anesthesia. 20, 3, p. 217-221 5 p.

Research output: Contribution to journalArticle

General Anesthesia
Formaldehyde
Anesthetics
Spinal Anesthesia
Pain
2 Citations (Scopus)

The effect of pre-emptive fentanyl on formalin pain in mice

Fu, E. & Scharf, J. E., Jan 1 1995, In : Regional Anesthesia. 20, 4, p. 291-295 5 p.

Research output: Contribution to journalArticle

Fentanyl
Formaldehyde
Pain
Injections
Anesthesia
1994
67 Citations (Scopus)

A prospective, randomized, double-blind comparison of epidural and intravenous sufentanil infusions

Miguel, R., Barlow, I., Morrell, M., Scharf, J., Sanusi, D. & Fu, E., Oct 25 1994, In : Anesthesiology. 81, 2, p. 346-352 7 p.

Research output: Contribution to journalArticle

Sufentanil
Intravenous Infusions
Morphine
Pain
Nausea
23 Citations (Scopus)

Pneumothorax during laparoscopic Nissen fundoplication

Mangar, D., Kirchhoff, G. T., Leal, J. J., Laborde, R. & Fu, E., Sep 1 1994, In : Canadian Journal of Anaesthesia. 41, 9, p. 854-856 3 p.

Research output: Contribution to journalArticle

Fundoplication
Pneumothorax
Oxygen
Respiratory Sounds
Carbon Dioxide

The effect of pre- versus post-emptive narcotic administration on acute formalin pain in mice

Fu, E. & Scharf, J. E., Jan 1 1994, In : Regional Anesthesia. 19, 2 SUPPL.

Research output: Contribution to journalArticle

Narcotics
Acute Pain
Formaldehyde