Elina Linetsky

Research Assistant Professor

  • 576 Citations
19942017
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Research Output 1994 2017

  • 576 Citations
  • 23 Article
  • 1 Letter
2017
37 Citations (Scopus)

Bioengineering of an intraabdominal endocrine pancreas

Baidal, D., Ricordi, C., Berman-Weinberg, D., Alvarez, A., Padilla, N., Ciancio, G., Linetsky, E., Pileggi, A. & Alejandro, R., May 11 2017, In : New England Journal of Medicine. 376, 19, 19.

Research output: Contribution to journalLetter

Bioengineering
Islets of Langerhans Transplantation
Type 1 Diabetes Mellitus
Islets of Langerhans
Blood Glucose
2016
14 Citations (Scopus)

A multicenter study: North american islet donor score in donor pancreas selection for human islet isolation for transplantation

Wang, L. J., Kin, T., O’Gorman, D., Shapiro, A. M. J., Naziruddin, B., Takita, M., Levy, M. F., Posselt, A. M., Szot, G. L., Savari, O., Barbaro, B., McGarrigle, J., Yeh, C., Oberholzer, J., Lei, J., Chen, T., Lian, M., Markmann, J. F., Alvarez, A., Linetsky, E. & 16 others, Ricordi, C., Balamurugan, A. N., Loganathan, G., Wilhelm, J. J., Hering, B. J., Bottino, R., Trucco, M., Liu, C., Min, Z., Li, Y., Naji, A., Fernandez, L. A., Ziemelis, M., Danobeitia, J. S., Millis, J. M. & Witkowski, P., 2016, In : Cell Transplantation. 25, 8, p. 1515-1523 9 p.

Research output: Contribution to journalArticle

Donor Selection
Islets of Langerhans Transplantation
Multicenter Studies
Logistics
Pancreas
6 Citations (Scopus)

Fully automated islet cell counter (ICC) for the assessment of islet mass, purity, and size distribution by digital image analysis

Buchwald, P., Bernal, A., Echeverri, F., Tamayo-Garcia, A., Linetsky, E. & Ricordi, C., 2016, In : Cell Transplantation. 25, 10, p. 1747-1761 15 p.

Research output: Contribution to journalArticle

Weibull distribution
Islets of Langerhans
Image analysis
Distribution functions
Particle size
46 Citations (Scopus)

National institutes of health-sponsored clinical islet transplantation consortium phase 3 trial: Manufacture of a complex cellular product at eight processing facilities

Ricordi, C., Goldstein, J. S., Balamurugan, A. N., Szot, G. L., Kin, T., Liu, C., Czarniecki, C. W., Barbaro, B., Bridges, N. D., Cano, J., Clarke, W. R., Eggerman, T. L., Hunsicker, L. G., Kaufman, D. B., Khan, A., Lafontant, D. E., Linetsky, E., Luo, X., Markmann, J. F., Naji, A. & 14 others, Korsgren, O., Oberholzer, J., Turgeon, N. A., Brandhorst, D., Friberg, A. S., Lei, J., Wang, L. J., Wilhelm, J. J., Willits, J., Zhang, X., Hering, B. J., Posselt, A. M., Stock, P. G. & Shapiro, A. M. J., Nov 1 2016, In : Diabetes. 65, 11, p. 3418-3428 11 p.

Research output: Contribution to journalArticle

Islets of Langerhans Transplantation
National Institutes of Health (U.S.)
Islets of Langerhans
Type 1 Diabetes Mellitus
Pancreas
2008
5 Citations (Scopus)

Regulatory Challenges in Manufacturing of Pancreatic Islets

Linetsky, E. & Ricordi, C., Mar 1 2008, In : Transplantation Proceedings. 40, 2, p. 424-426 3 p.

Research output: Contribution to journalArticle

Islets of Langerhans
Investigational New Drug Application
United States Food and Drug Administration
Licensure
Type 1 Diabetes Mellitus
2005
34 Citations (Scopus)

Prolonged allogeneic islet graft survival by protoporphyrins

Pileggi, A., Molano, R., Berney, T., Ichii, H., San Jose, S., Zahr, E., Poggioli, R., Linetsky, E., Ricordi, C. & Inverardi, L. A., May 13 2005, In : Cell Transplantation. 14, 2-3, p. 85-96 12 p.

Research output: Contribution to journalArticle

Protoporphyrins
Graft Survival
Grafts
Transplants
Immunosuppression
2004
12 Citations (Scopus)

Targeted bone marrow radioablation with 153Samarium-Lexidronam promotes allogeneic hematopoietic chimerism and donor-specific immunologic hyporesponsiveness

Inverardi, L. A., Linetsky, E., Pileggi, A., Molano, R., Serafini, A. N., Paganelli, G. & Ricordi, C., Mar 15 2004, In : Transplantation. 77, 5, p. 647-655 9 p.

Research output: Contribution to journalArticle

Chimerism
Bone Marrow
Bone Marrow Transplantation
Transplantation Tolerance
T-Lymphocytes
1999
6 Citations (Scopus)

Interferon-gamma gene expression during acute graft-versus-host disease: Relationship to MHC induction and tissue injury

Parfrey, N. A., El-Sheikh, A., Monckton, E. A., Cockfield, S. M., Halloran, P. F. & Linetsky, E., Sep 6 1999, In : Journal of Pathology. 189, 1, p. 99-104 6 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Major Histocompatibility Complex
Interferons
Interferon-gamma
Gene Expression
1998
11 Citations (Scopus)

Endotoxin contamination of reagents used during isolation and purification of human pancreatic islets

Linetsky, E., Inverardi, L. A., Kenyon, N. S., Alejandro, R. & Ricordi, C., May 18 1998, In : Transplantation Proceedings. 30, 2, p. 345-346 2 p.

Research output: Contribution to journalArticle

Drug Contamination
Islets of Langerhans Transplantation
Macrophage Activation
Cell Separation
Homologous Transplantation
1997
7 Citations (Scopus)

Human islet isolation using a new enzyme blend

Linetsky, E., Lehmann, R., Li, H., Fernandez, L., Bottino, R., Selvaggi, G., Alejandro, R. & Ricordi, C., Jul 7 1997, In : Transplantation Proceedings. 29, 4, p. 1957-1958 2 p.

Research output: Contribution to journalArticle

Cell Separation
Automation
Collagenases
Islets of Langerhans
Reproducibility of Results
3 Citations (Scopus)

Human mixed lymphocyte-islet cultures: The influence of heterologous proteins on islet immunogenicity

Inverardi, L. A., Linetsky, E., Kenyon, N. S., Socci, C. & Ricordi, C., Jul 7 1997, In : Transplantation Proceedings. 29, 4

Research output: Contribution to journalArticle

Lymphocyte Activation
Coculture Techniques
Islets of Langerhans
Reproducibility of Results
Culture Media
249 Citations (Scopus)

Improved human islet isolation using a new enzyme blend, liberase

Linetsky, E., Bottino, R., Lehmann, R., Alejandro, R., Inverardi, L. A. & Ricordi, C., Jul 9 1997, In : Diabetes. 46, 7, p. 1120-1123 4 p.

Research output: Contribution to journalArticle

Collagenases
Enzymes
Pancreas
Digestion
Cold Ischemia
1 Citation (Scopus)
Mixed Lymphocyte Culture Test
Cell Separation
Bovine Serum Albumin
Human Body
Serum Albumin
2 Citations (Scopus)

Influence of variables on canine islet isolation results

Fernandez, L., Lehmann, R., Selvaggi, G., Kong, S. S., Bottino, R., Li, H., Linetsky, E., Kenyon, N. S., Alejandro, R. & Ricordi, C., Jul 7 1997, In : Transplantation Proceedings. 29, 4

Research output: Contribution to journalArticle

Organ Size
Cell Separation
Collagenases
Islets of Langerhans
Canidae
1 Citation (Scopus)

Variables affecting human vertebral body marrow yields

Linetsky, E., Li, H., Fernandez, L., Bottino, R., Lehmann, R., Selvaggi, G. & Ricordi, C., Jul 7 1997, In : Transplantation Proceedings. 29, 4

Research output: Contribution to journalArticle

Cell Separation
Human Body
Sex Characteristics
Bone Marrow Cells
Spine
1996
59 Citations (Scopus)

Identification by subtractive hybridization of a spectrum of novel and unexpected genes associated with in vitro differentiation of human cytotrophoblast cells

Morrish, D. W., Linetsky, E., Bhardwaj, D., Li, H., Dakour, J., Marsh, R. G., Paterson, M. C. & Godbout, R., Jan 1 1996, In : Placenta. 17, 7, p. 431-441 11 p.

Research output: Contribution to journalArticle

Trophoblasts
Genes
Epidermal Growth Factor
Placenta
3-Hydroxysteroid Dehydrogenases
1995
2 Citations (Scopus)

A simple method for depletion of bone fragments from human vertebral body marrow

Kong, S. S., Selvaggi, G., Kenyon, N. S., Bottino, R., Linetsky, E. & Ricordi, C., Dec 1 1995, In : Transplantation Proceedings. 27, 6

Research output: Contribution to journalArticle

Immunologic Graft Enhancement
Colony-Forming Units Assay
Cell Separation
Bone Marrow Transplantation
Centrifugation
1 Citation (Scopus)
Immunologic Graft Enhancement
CD34 Antigens
Colony-Forming Units Assay
Cell Separation
Hematopoietic Stem Cells
2 Citations (Scopus)

Automation of human vertebral body bone marrow isolation

Bottino, R., Linetsky, E., Selvaggi, G., Kong, S. S., Qian, T. & Ricordi, C., Dec 1 1995, In : Annals of the New York Academy of Sciences. 770, p. 364-365 2 p.

Research output: Contribution to journalArticle

Automation
Human Body
Bone Marrow
Isolation
15 Citations (Scopus)

Comparison of collagenase type P and liberase during human islet isolation using the automated method

Linetsky, E., Selvaggi, G., Bottino, R., Kong, S. S., Qian, T., Alejandro, R. & Ricordi, C., Dec 1 1995, In : Transplantation Proceedings. 27, 6

Research output: Contribution to journalArticle

Thermolysin
Islets of Langerhans Transplantation
Cell Separation
Collagenases
Islets of Langerhans
11 Citations (Scopus)

Enhanced allograft acceptance by multiple infusions of donor bone marrow in humans

Ricordi, C., Karatzas, T., Selvaggi, G., Neri, J., Fernandez, H., Ruiz, M. P., Linetsky, E., Kong, S. S., Webb, M., Bottino, R., Quian, T., Ciancio, G., Carreno, M., Cirocco, R., Garcia, R., Olsen, L., Esquinazi, V., Miller, J., Schiff, E. R. & Tzakis, A. G., Dec 1 1995, In : Transplantation Proceedings. 27, 6

Research output: Contribution to journalArticle

Immunologic Graft Enhancement
Islets of Langerhans Transplantation
Histocompatibility Testing
Graft Rejection
Graft Survival
2 Citations (Scopus)

Human vertebral body bone marrow harvest: Comparison between manual and automated methods

Bottino, R., Linetsky, E., Selvaggi, G., Kong, S. S., Qian, T. & Ricordi, C., Dec 1 1995, In : Transplantation Proceedings. 27, 6

Research output: Contribution to journalArticle

Transplantation Immunology
Immune Tolerance
Cell Separation
Human Body
Cadaver
7 Citations (Scopus)

Islet transplantation in type II diabetes

Ricordi, C., Angelico, M. C., Alejandro, R., Bottino, R., Linetsky, E., Selvaggi, G., Mintz, D. H. & Tzakis, A., Dec 1 1995, In : Transplantation Proceedings. 27, 6

Research output: Contribution to journalArticle

Islets of Langerhans Transplantation
Bone Marrow Transplantation
Liver Cirrhosis
Liver Transplantation
Kidney Transplantation
1994
43 Citations (Scopus)

Expression of c-fos protein in rat brain elicited by electrical and chemical stimulation of the hypothalamic paraventricular nucleus

Krukoff, T. L., Harris, K. H., Linetsky, E. & Jhamandas, J. H., Jan 1 1994, In : Neuroendocrinology. 59, 6, p. 590-602 13 p.

Research output: Contribution to journalArticle

Chemical Stimulation
Proto-Oncogene Proteins c-fos
Paraventricular Hypothalamic Nucleus
Electric Stimulation
Hypothalamus