Eli Gilboa

Professor

  • 18162 Citations
1973 …2020
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Dendritic Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
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T-Lymphocytes Medicine & Life Sciences
Genes Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Moloney murine leukemia virus Medicine & Life Sciences

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Projects 1983 2020

Reversing HIV T cell dysfunction by aptamer targeting of therapeutic siRNAs

Gilboa, E.

National Institutes of Health

3/1/151/31/20

Project: Research projectNIH Director’s Pioneer Award (NDPA)

HIV
T-Lymphocytes
Small Interfering RNA
Ligands
Therapeutics
Immunologic Memory
Small Interfering RNA
T-Lymphocytes
Immunity
Vaccines
Nonsense Mediated mRNA Decay
Neoplasm Antigens
Neoplasms
Small Interfering RNA
Immune System

Oligonucleotide aptamer ligands to reverse T cell anergy in HIV-infected patients

Gilboa, E.

National Institutes of Health

6/15/105/31/13

Project: Research projectExploratory/Developmental Grants

Oligonucleotides
HIV
Ligands
T-Lymphocytes
Immunity

Development of Oligonucleotide-based CTLA-4 Inhibitors

Gilboa, E.

National Institutes of Health

4/1/043/31/10

Project: Research projectResearch Project

Oligonucleotides
Organized Financing
Immunotherapy
CD27 Antigens
Antigens

Research Output 1973 2018

1 Citations

An rna toolbox for cancer immunotherapy

Pastor, F., Berraondo, P., Etxeberria, I., Frederick, J., Sahin, U., Gilboa, E. & Melero, I., Oct 1 2018, In : Nature Reviews Drug Discovery. 17, 10, p. 751-767 17 p.

Research output: Contribution to journalReview article

Immunotherapy
RNA
Neoplasms
Cancer Vaccines
Nucleotide Aptamers

Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity

Schrand, B., Clark, E., Levay, A., Capote, A. R., Martinez, O., Brenneman, R., Castro, I. & Gilboa, E., Dec 1 2018, In : Nature communications. 9, 1, 3348.

Research output: Contribution to journalArticle

Neoplasm Antibodies
Haptens
immunity
antibodies
Tumors
2 Citations

NFκB in Pancreatic Stellate Cells Reduces Infiltration of Tumors by Cytotoxic T Cells and Killing of Cancer Cells, via Up-regulation of CXCL12

Garg, B., Giri, B., Modi, S., Sethi, V., Castro, I., Umland, O., Ban, Y., Lavania, S., Dawra, R., Banerjee, S., Vickers, S., Merchant, N., Chen, S. X., Gilboa, E., Ramakrishnan, S., Saluja, A. & Dudeja, V., Sep 1 2018, In : Gastroenterology. 155, 3, p. 880-891.e8

Research output: Contribution to journalArticle

Pancreatic Stellate Cells
Up-Regulation
T-Lymphocytes
Neoplasms
Inbred C57BL Mouse
2 Citations

Potentiating tumor immunity using aptamer-targeted RNAi to render CD8+ T cells resistant to TGFβ inhibition

Puplampu-Dove, Y., Gefen, T., Rajagopalan, A., Muheramagic, D., Schrand, B. & Gilboa, E., Feb 14 2018, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

RNA Interference
Immunity
T-Lymphocytes
Neoplasms
Small Interfering RNA
13 Citations

Aptamer-Targeted Attenuation of IL-2 Signaling in CD8+ T Cells Enhances Antitumor Immunity

Rajagopalan, A., Berezhnoy, A., Schrand, B., Puplampu-Dove, Y. & Gilboa, E., Jan 4 2017, In : Molecular Therapy. 25, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Interleukin-2
Immunity
Small Interfering RNA
T-Lymphocytes
Axin Signaling Complex