Diego A Caicedo-Vierkant

Professor

  • 3629 Citations
1993 …2022

Research output per year

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Research Output

  • 3629 Citations
  • 57 Article
  • 1 Chapter
  • 1 Comment/debate
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Article
2019

In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice

Abdulreda, M. H., Molano, R. D., Faleo, G., Lopez-Cabezas, M., Shishido, A., Ulissi, U., Fotino, C., Hernandez, L. F., Tschiggfrie, A., Aldrich, V. R., Tamayo-Garcia, A., Bayer, A. L., Ricordi, C., Caicedo-Vierkant, D. A., Buchwald, P., Pileggi, A. & Berggren, P. O., Jan 1 2019, In : Diabetologia.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

Rodriguez Diaz, R., Molano, R., Weitz, J. R., Abdulreda, M. H., Berman-Weinberg, D., Leibiger, B., Leibiger, I. B., Kenyon, N. S., Ricordi, C., Pileggi, A., Caicedo-Vierkant, D. A. & Berggren, P. O., Mar 6 2018, In : Cell Metabolism. 27, 3, p. 549-558.e4

Research output: Contribution to journalArticle

27 Scopus citations

The Pericyte of the Pancreatic Islet Regulates Capillary Diameter and Local Blood Flow

Almaca, J., Weitz, J., Rodriguez Diaz, R., Pereira, E. & Caicedo-Vierkant, D. A., Mar 6 2018, In : Cell Metabolism. 27, 3, p. 630-644.e4

Research output: Contribution to journalArticle

17 Scopus citations
2017

Confocal imaging of neuropeptide Y-pHluorin: A technique to visualize insulin granule exocytosis in intact murine and human islets

Makhmutova, M., Liang, T., Gaisano, H., Caicedo-Vierkant, D. A. & Almaca, J., Sep 13 2017, In : Journal of Visualized Experiments. 2017, 127, e56089.

Research output: Contribution to journalArticle

4 Scopus citations

Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity

Weitz, J. R., Makhmutova, M., Almaca, J., Stertmann, J., Aamodt, K., Brissova, M., Speier, S., Rodriguez Diaz, R. & Caicedo-Vierkant, D. A., Sep 7 2017, (Accepted/In press) In : Diabetologia. p. 1-11 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
5 Scopus citations

Resealable, optically accessible, PDMS-free fluidic platform for ex vivo interrogation of pancreatic islets

Lenguito, G., Chaimov, D., Weitz, J. R., Rodriguez Diaz, R., Rawal, S. A. K., Tamayo-Garcia, A., Caicedo-Vierkant, D. A., Stabler, C. L., Buchwald, P. & Agarwal, A., 2017, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 17, 5, p. 772-781 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

β-Arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions

Zhu, L., Almaca, J., Dadi, P. K., Hong, H., Sakamoto, W., Rossi, M., Lee, R. J., Vierra, N. C., Lu, H., Cui, Y., McMillin, S. M., Perry, N. A., Gurevich, V. V., Lee, A., Kuo, B., Leapman, R. D., Matschinsky, F. M., Doliba, N. M., Urs, N. M., Caron, M. G. & 3 others, Jacobson, D. A., Caicedo-Vierkant, D. A. & Wess, J., Feb 1 2017, In : Nature Communications. 8, 14295.

Research output: Contribution to journalArticle

17 Scopus citations
2016

Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells

Almaca, J., Molina, J., Menegaz, D., Pronin, A. N., Tamayo, A., Slepak, V. Z., Berggren, P. O. & Caicedo-Vierkant, D. A., Dec 20 2016, In : Cell Reports. 17, 12, p. 3281-3291 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Liraglutide compromises pancreatic β cell function in a humanized mouse model

Abdulreda, M. H., Rodriguez Diaz, R., Caicedo-Vierkant, D. A. & Berggren, P. O., Mar 8 2016, In : Cell Metabolism. 23, 3, p. 541-546 6 p.

Research output: Contribution to journalArticle

32 Scopus citations
2015

Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets

Almaca, J., Liang, T., Gaisano, H. Y., Nam, H. G., Berggren, P. O. & Caicedo-Vierkant, D. A., Sep 16 2015, (Accepted/In press) In : Diabetologia.

Research output: Contribution to journalArticle

14 Scopus citations
2014

Control of insulin secretion by cholinergic signaling in the human pancreatic islet

Molina, J., Rodriguez Diaz, R., Fachado, A., Jacques-Silva, M. C., Berggren, P. O. & Caicedo-Vierkant, D. A., Jan 1 2014, In : Diabetes. 63, 8, p. 2714-2726 13 p.

Research output: Contribution to journalArticle

62 Scopus citations

In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye

Kistler, A. D., Caicedo-Vierkant, D. A., Abdulreda, M. H., Faul, C. H., Kerjaschki, D., Berggren, P. O., Reiser, J. & Fornoni, A., Jan 27 2014, In : Scientific Reports. 4, 3872.

Research output: Contribution to journalArticle

14 Scopus citations

Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic β-cells and disrupts glucose homeostasis

Medina, M. C., Fonesca, T. L., Molina, J., Fachado, A., Castillo, M., Dong, L., Soares, R., Hernández, A., Caicedo-Vierkant, D. A. & Bianco, A. C., Jan 1 2014, In : Endocrinology. 155, 8, p. 3160-3171 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Neural control of the endocrine pancreas

Rodriguez Diaz, R. & Caicedo-Vierkant, D. A., Oct 1 2014, In : Best Practice and Research: Clinical Endocrinology and Metabolism. 28, 5, p. 745-756 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

Neurotransmitters act as paracrine signals to regulate insulin secretion from the human pancreatic islet

Rodriguez Diaz, R., Menegaz, D. & Caicedo-Vierkant, D. A., Aug 15 2014, In : Journal of Physiology. 592, 16, p. 3413-3417 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Young capillary vessels rejuvenate aged pancreatic islets

Almaca, J., Molina, J., Drigo, R. A., Abdulreda, M. H., Jeon, W. B., Berggren, P. O., Caicedo-Vierkant, D. A. & Nam, H. G., Dec 9 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 49, p. 17612-17617 6 p.

Research output: Contribution to journalArticle

37 Scopus citations
2013

Bone marrow transplantation transfers age-related susceptibility to neovascular remodeling in murine laser- induced choroidal neovascularization

Espinosa-Heidmann, D. G., Malek, G., Mettu, P. S., Caicedo-Vierkant, D. A., Saloupis, P., Gach, S., Dunnon, A. K., Hu, P., Spiga, M. G. & Cousins, S. W., Oct 17 2013, In : Investigative Ophthalmology and Visual Science. 54, 12, p. 7439-7449 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Coordination of hypothalamic and pituitary T3 production regulates TSH expression

Fonseca, T. L., Correa-Medina, M., Campos, M. P. O., Wittmann, G., Werneck-de-Castro, J. P., Drigo, R. A., Mora-Garzon, M., Ueta, C. B., Caicedo-Vierkant, D. A., Fekete, C., Gereben, B., Lechan, R. M. & Bianco, A. C., Apr 1 2013, In : Journal of Clinical Investigation. 123, 4, p. 1492-1500 9 p.

Research output: Contribution to journalArticle

83 Scopus citations
16 Scopus citations
72 Scopus citations
13 Scopus citations
2012

Non-invasive in vivo imaging of pancreatic β-cell function and survival - a perspective

Leibiger, I. B., Caicedo-Vierkant, D. A. & Berggren, P. O., Feb 1 2012, In : Acta Physiologica. 204, 2, p. 178-185 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

Rodriguez Diaz, R., Speier, S., Molano, R., Formoso, A., Gans, I., Abdulreda, M. H., Cabrera, O., Molina, J., Fachado, A., Ricordi, C., Leibiger, I., Pileggi, A., Berggren, P. O. & Caicedo-Vierkant, D. A., Dec 26 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 52, p. 21456-21461 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Real-time detection of acetylcholine release from the human endocrine pancreas

Rodriguez Diaz, R., Dando, R., Huang, Y. A., Berggren, P. O., Roper, S. D. & Caicedo-Vierkant, D. A., Jun 1 2012, In : Nature Protocols. 7, 6, p. 1015-1023 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

Rodriguez Diaz, R., Dando, R., Jacques-Silva, M. C., Fachado, A., Molina, J., Abdulreda, M. H., Ricordi, C., Roper, S. D., Berggren, P. O. & Caicedo-Vierkant, D. A., Jul 1 2011, In : Nature Medicine. 17, 7, p. 888-892 5 p.

Research output: Contribution to journalArticle

150 Scopus citations

Donor islet endothelial cells in pancreatic islet revascularization

Nyqvist, D., Speier, S., Rodriguez Diaz, R., Molano, R., Lipovsek, S., Rupnik, M., Dicker, A., Ilegems, E., Zahr-Akrawi, E., Molina, J., Lopez-Cabeza, M., Villate, S., Abdulreda, M. H., Ricordi, C., Caicedo-Vierkant, D. A., Pileggi, A. & Berggren, P. O., Oct 1 2011, In : Diabetes. 60, 10, p. 2571-2577 7 p.

Research output: Contribution to journalArticle

62 Scopus citations

High-resolution, noninvasive longitudinal live imaging of immune responses

Abdulreda, M. H., Faleo, G., Molano, R., Lopez-Cabezas, M., Molina, J., Tan, Y., Ron Echeverria, O. A., Zahr-Akrawi, E., Rodriguez Diaz, R., Edlund, P. K., Leibiger, I., Bayer, A. L., Perez Quinones, V. L., Ricordi, C., Caicedo-Vierkant, D. A., Pileggi, A. & Berggren, P. O., Aug 2 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 31, p. 12863-12868 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Innervation patterns of autonomic axons in the human endocrine pancreas

Rodriguez Diaz, R., Abdulreda, M. H., Formoso, A. L., Gans, I., Ricordi, C., Berggren, P. O. & Caicedo-Vierkant, D. A., Jul 6 2011, In : Cell Metabolism. 14, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

169 Scopus citations

The anterior chamber of the eye as a clinical transplantation site for the treatment of diabetes: A study in a baboon model of diabetes

Perez Quinones, V. L., Caicedo-Vierkant, D. A., Berman-Weinberg, D., Arrieta Quintero, E., Abdulreda, M. H., Rodriguez Diaz, R., Pileggi, A., Hernandez, E., Dubovy, S., Parel, J-M. A., Ricordi, C., Kenyon, N. M., Kenyon, N. S. & Berggren, P. O., May 1 2011, In : Diabetologia. 54, 5, p. 1121-1126 6 p.

Research output: Contribution to journalArticle

51 Scopus citations
2010

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic β cell

Jacques-Silva, M. C., Correa-Medina, M., Cabrera, O., Rodriguez Diaz, R., Makeeva, N., Fachado, A., Diez, J., Berman-Weinberg, D., Kenyon, N. S., Ricordi, C., Pileggi, A., Molano, R., Berggren, P. O. & Caicedo-Vierkant, D. A., Apr 6 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 14, p. 6465-6470 6 p.

Research output: Contribution to journalArticle

87 Scopus citations
2008

Automated, high-throughput assays for evaluation of human pancreatic islet function

Cabrera, O., Jacques-Silva, M. C., Berman-Weinberg, D., Fachado, A., Echeverri, F., Poo, R., Khan, A., Kenyon, N. S., Ricordi, C., Berggren, P. O. & Caicedo-Vierkant, D. A., May 30 2008, In : Cell Transplantation. 16, 10, p. 1039-1048 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Glutamate Is a Positive Autocrine Signal for Glucagon Release

Cabrera, O., Jacques-Silva, M. C., Speier, S., Yang, S. N., Köhler, M., Fachado, A., Vieira, E., Zierath, J. R., Kibbey, R., Berman-Weinberg, D., Kenyon, N. S., Ricordi, C., Caicedo-Vierkant, D. A. & Berggren, P. O., Jun 4 2008, In : Cell Metabolism. 7, 6, p. 545-554 10 p.

Research output: Contribution to journalArticle

105 Scopus citations

Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice

Kim, J. W., Roberts, C. D., Berg, S. A., Caicedo-Vierkant, D. A., Roper, S. D. & Chaudhari, N., May 7 2008, In : PLoS One. 3, 5, e2127.

Research output: Contribution to journalArticle

24 Scopus citations

Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye

Speier, S., Nyqvist, D., Köhler, M., Caicedo-Vierkant, D. A., Leibiger, I. B. & Berggren, P. O., Sep 2 2008, In : Nature Protocols. 3, 8, p. 1278-1286 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

Noninvasive in vivo imaging of pancreatic islet cell biology

Speier, S., Nyqvist, D., Cabrera, O., Yu, J., Molano, R., Pileggi, A., Moede, T., Köhler, M., Wilbertz, J., Leibiger, B., Ricordi, C., Leibiger, I. B., Caicedo-Vierkant, D. A. & Berggren, P. O., May 1 2008, In : Nature Medicine. 14, 5, p. 574-578 5 p.

Research output: Contribution to journalArticle

161 Scopus citations
2006
679 Scopus citations
2005

A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations

Ichii, H., Inverardi, L. A., Pileggi, A., Molano, R., Cabrera, O., Caicedo-Vierkant, D. A., Messinger, S., Kuroda, Y., Berggren, P. O. & Ricordi, C., Jul 1 2005, In : American Journal of Transplantation. 5, 7, p. 1635-1645 11 p.

Research output: Contribution to journalArticle

153 Scopus citations

Blood-derived macrophages infiltrate the retina and activate Muller glial cells under experimental choroidal neovascularization

Caicedo-Vierkant, D. A., Espinosa-Heidmann, D. G., Piña, Y., Hernandez, E. P. & Cousins, S. W., Jul 1 2005, In : Experimental Eye Research. 81, 1, p. 38-47 10 p.

Research output: Contribution to journalArticle

108 Scopus citations

Photoreceptor synapses degenerate early in experimental choroidal neovascularization

Caicedo-Vierkant, D. A., Espinosa-Heidmann, D. G., Hamasaki, D., Piña, Y. & Cousins, S. W., Mar 14 2005, In : Journal of Comparative Neurology. 483, 3, p. 263-277 15 p.

Research output: Contribution to journalArticle

17 Scopus citations

Quantitative enumeration of vascular smooth muscle cells and endothelial cells derived from bone marrow precursors in experimental choroidal neovascularization

Espinosa-Heidmann, D. G., Reinoso, M. A., Pina, Y., Csaky, K. G., Caicedo-Vierkant, D. A. & Cousins, S. W., Mar 1 2005, In : Experimental Eye Research. 80, 3, p. 369-378 10 p.

Research output: Contribution to journalArticle

66 Scopus citations
2004

Rat gustatory neurons in the geniculate ganglion express glutamate receptor subunits

Caicedo-Vierkant, D. A., Zucchi, B., Pereira, E. & Roper, S. D., Dec 1 2004, In : Chemical Senses. 29, 6, p. 463-471 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Transient Ca2+-permeable AMPA receptors in postnatal rat primary auditory neurons

Eybalin, M., Caicedo-Vierkant, D. A., Renard, N., Ruel, J. & Puel, J. L., Dec 1 2004, In : European Journal of Neuroscience. 20, 11, p. 2981-2989 9 p.

Research output: Contribution to journalArticle

43 Scopus citations
2003

Bone Marrow-Derived Progenitor Cells Contribute to Experimental Choroidal Neovascularization

Espinosa-Heidmann, D. G., Caicedo-Vierkant, D. A., Hernandez, E. P., Csaky, K. G. & Cousins, S. W., Nov 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 11, p. 4914-4919 6 p.

Research output: Contribution to journalArticle

121 Scopus citations

Role of the G-Protein Subunit α-Gustducin in Taste Cell Responses to Bitter Stimuli

Caicedo-Vierkant, D. A., Pereira, E., Margolskee, R. F. & Roper, S. D., Oct 29 2003, In : Journal of Neuroscience. 23, 30, p. 9947-9952 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Sour taste stimuli evoke Ca2+ and pH responses in mouse taste cells

Richter, T. A., Caicedo-Vierkant, D. A. & Roper, S. D., Mar 1 2003, In : Journal of Physiology. 547, 2, p. 475-483 9 p.

Research output: Contribution to journalArticle

89 Scopus citations
2002

Individual mouse taste cells respond to multiple chemical stimuli

Caicedo-Vierkant, D. A., Kim, K. N. & Roper, S. D., Oct 15 2002, In : Journal of Physiology. 544, 2, p. 501-509 9 p.

Research output: Contribution to journalArticle

93 Scopus citations
2001

Glutamate-induced cobalt uptake reveals non-NMDA receptors in developing rat taste buds

Kim, K. N., Caicedo-Vierkant, D. A. & Roper, S. D., Jun 13 2001, In : NeuroReport. 12, 8, p. 1715-1718 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Taste receptor cells that discriminate between bitter stimuli

Caicedo-Vierkant, D. A. & Roper, S. D., Feb 23 2001, In : Science. 291, 5508, p. 1557-1560 4 p.

Research output: Contribution to journalArticle

141 Scopus citations