Derek M Dykxhoorn

Research Associate Professor

  • 8024 Citations
19962020
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RNA Interference Medicine & Life Sciences
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RNA Chemical Compounds
Gene Silencing Medicine & Life Sciences
HIV Infections Medicine & Life Sciences
HIV-1 Medicine & Life Sciences

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Projects 2010 2020

Anti-Arrhythmia Agents
Unsaturated Fatty Acids
Cardiac Myocytes
Long QT Syndrome
Action Potentials

Genetics of Parkinsonism

Scott, W. K., Beecham, G. W., Vance, J. M., Wahlestedt, C. R., Wahlestedt, C. R., Dykxhoorn, D. M., Wahlestedt, C. R. & Dykxhoorn, D. M.

National Institutes of Health

9/15/108/31/18

Project: Research project

Parkinson Disease
Exome
Parkinsonian Disorders
Genes
Inborn Genetic Diseases
Anti-Infective Agents
Small Interfering RNA
HIV
Virus Diseases
Virus Integration

Research Output 1996 2019

  • 8024 Citations
  • 59 Article
  • 5 Chapter
  • 1 Comment/debate
  • 1 Review article

Tumor Suppressors RB1 and CDKN2a Cooperatively Regulate Cell-Cycle Progression and Differentiation During Cardiomyocyte Development and Repair

Hatzistergos, K. E., Williams, A. R., Dykxhoorn, D. M., Bellio, M. A., Yu, W. & Hare, J., Apr 12 2019, In : Circulation research. 124, 8, p. 1184-1197 14 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase Inhibitor p16
Cardiac Myocytes
Pluripotent Stem Cells
Cell Differentiation
Cell Cycle
1 Citation (Scopus)

Cocaine exposure increases blood pressure and aortic stiffness via the mir-30c-5p-malic enzyme 1-reactive oxygen species pathway

Zhu, W., Wang, H., Wei, J., Sartor, G., Bao, M. M., Pierce, C. T., Wahlestedt, C. R., Dykxhoorn, D. M. & Dong, C., Jan 1 2018, In : Hypertension. 71, 4, p. 752-760 9 p.

Research output: Contribution to journalArticle

malate dehydrogenase (decarboxylating)
Vascular Stiffness
Cocaine
Reactive Oxygen Species
Blood Pressure
3 Citations (Scopus)

Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons

Derosa, B. A., El Hokayem, J., Artimovich, E., Garcia-Serje, C., Phillips, A. W., Van Booven, D., Nestor, J. E., Wang, L., Cuccaro, M., Vance, J. M., Pericak-Vance, M. A., Cukier, H. N., Nestor, M. W. & Dykxhoorn, D. M., Dec 1 2018, In : Scientific Reports. 8, 1, 8423.

Research output: Contribution to journalArticle

Autistic Disorder
Neurons
Induced Pluripotent Stem Cells
Gene Expression Profiling
Genes
2 Citations (Scopus)

Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules

Asumda, F. Z., Hatzistergos, K. E., Dykxhoorn, D. M., Jakubski, S., Edwards, J., Thomas, E. & Schiff, E. R., May 1 2018, In : Differentiation. 101, p. 16-24 9 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Hepatocytes
Endoderm
Periodic Acid
Regenerative Medicine

Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia

Scott, W. K., Medie, F. M., Ruffin, F., Sharma-Kuinkel, B. K., Cyr, D. D., Guo, S., Dykxhoorn, D. M., Skov, R. L., Bruun, N. E., Dahl, A., Lerche, C. J., Petersen, A., Larsen, A. R., Lauridsen, T. K., Johansen, H. K., Ullum, H., Sørensen, E., Hassager, C., Bundgaard, H., Schønheyder, H. C. & 9 othersTorp-Pedersen, C., Østergaard, L. B., Arpi, M., Rosenvinge, F., Erikstrup, L. T., Chehri, M., Søgaard, P., Andersen, P. S. & Fowler, V. G., Oct 1 2018, In : PLoS Genetics. 14, 10, e1007667.

Research output: Contribution to journalArticle

Open Access
middle-aged adults
glutaminase
Glutaminase
Staphylococcal Infections
bacteremia