Claes R Wahlestedt

Professor

  • 27598 Citations
1976 …2021
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  • 16 Similar Profiles
Neuropeptide Y Medicine & Life Sciences
Long Noncoding RNA Medicine & Life Sciences
Genes Medicine & Life Sciences
Untranslated RNA Medicine & Life Sciences
Neuropeptide Y Receptors Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Small Interfering RNA Medicine & Life Sciences
Brain Medicine & Life Sciences

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Projects 1976 2021

Transcriptome
Alzheimer Disease
Long Noncoding RNA
Computational Biology
Phosphatidylinositol 3-Kinases
Epigenomics
Alcoholism
Alcohols
Reward
Drinking Behavior
MicroRNAs
Substance-Related Disorders
Cocaine
Neuronal Plasticity
Brain
Long Noncoding RNA
Cocaine-Related Disorders
Cocaine
Chromatin
Self Administration
Antisense RNA
Brain-Derived Neurotrophic Factor
Epigenomics
Untranslated RNA
Rett Syndrome

Research Output 1982 2019

CHAPTER 9: Oligonucleotide Targeting of Long Non-coding RNAs

Blokhin, I., Khorkova, O., Hsiao, J. & Wahlestedt, C. R., Jan 1 2019, Therapies for Retinal Degeneration: Targeting Common Processes. Agrawal, S. & Gait, M. J. (eds.). 68 ed. Royal Society of Chemistry, p. 181-205 25 p. (RSC Drug Discovery Series; vol. 2019-January, no. 68).

Research output: Chapter in Book/Report/Conference proceedingChapter

Long Noncoding RNA
Oligonucleotides
Untranslated RNA
Transcriptome
RNA Transport

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

Argemi, J., Latasa, M. U., Atkinson, S. R., Blokhin, I. O., Massey, V., Gue, J. P., Cabezas, J., Lozano, J. J., Van Booven, D., Bell, A., Cao, S., Vernetti, L. A., Arab, J. P., Ventura-Cots, M., Edmunds, L. R., Fondevilla, C., Stärkel, P., Dubuquoy, L., Louvet, A., Odena, G. & 20 others, Gomez, J. L., Aragon, T., Altamirano, J., Caballeria, J., Jurczak, M. J., Taylor, D. L., Berasain, C., Wahlestedt, C. R., Monga, S. P., Morgan, M. Y., Sancho-Bru, P., Mathurin, P., Furuya, S., Lackner, C., Rusyn, I., Shah, V. H., Thursz, M. R., Mann, J., Avila, M. A. & Bataller, R., Dec 1 2019, In : Nature communications. 10, 1, 3126.

Research output: Contribution to journalArticle

Open Access
hepatitis
Alcoholic Hepatitis
gene expression
Gene expression
Liver

Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways

Johnstone, A. L., Andrade, N. S., Barbier, E., Khomtchouk, B. B., Rienas, C. A., Lowe, K., Van Booven, D. J., Domi, E., Esanov, R., Vilca, S., Tapocik, J. D., Rodriguez, K., Maryanski, D., Keogh, M. C., Meinhardt, M. W., Sommer, W. H., Heilig, M., Zeier, Z. R. & Wahlestedt, C. R., Jan 1 2019, (Accepted/In press) In : Addiction Biology. e12816.

Research output: Contribution to journalArticle

Open Access
Histone Demethylases
Epigenomics
Alcoholism
Alcohols
Enzymes
2 Citations (Scopus)

Enhancement of BDNF expression and memory by HDAC inhibition requires BET bromodomain reader proteins

Sartor, G. C., Malvezzi, A. M., Kumar, A., Andrade, N. S., Wiedner, H. J., Vilca, S. J., Janczura, K. J., Bagheri, A., Al-Ali, H., Powell, S. K., Brown, P. T., Volmar, C. H., Foster, T. C., Zeier, Z. R. & Wahlestedt, C. R., Jan 23 2019, In : Journal of Neuroscience. 39, 4, p. 612-626 15 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Brain-Derived Neurotrophic Factor
Proteins
Histone Deacetylase Inhibitors
Messenger RNA

HDAC Inhibitors Induce BDNF Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons

Bagheri, A., Habibzadeh, P., Razavipour, S. F., Volmar, C. H., Chee, N. T., Brothers, S. P., Wahlestedt, C. R., Mowla, S. J. & Faghihi, M. A., Mar 5 2019, In : International journal of molecular sciences. 20, 5

Research output: Contribution to journalArticle

Open Access
Histone Deacetylase Inhibitors
Brain-Derived Neurotrophic Factor
neurons
inhibitors
Neurons