Claes R Wahlestedt


  • 24494 Citations
1976 …2021
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Epigenomics Medicine & Life Sciences
Brain Medicine & Life Sciences

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Projects 1976 2021

Alzheimer Disease
Long Noncoding RNA
Computational Biology
Phosphatidylinositol 3-Kinases
Drinking Behavior
Substance-Related Disorders
Neuronal Plasticity
Long Noncoding RNA
Cocaine-Related Disorders
Self Administration
Antisense RNA
Brain-Derived Neurotrophic Factor
Untranslated RNA
Rett Syndrome

Research Output 1982 2019

Enhancement of BDNF expression and memory by HDAC inhibition requires BET bromodomain reader proteins

Sartor, G. C., Malvezzi, A. M., Kumar, A., Andrade, N. S., Wiedner, H. J., Vilca, S. J., Janczura, K. J., Bagheri, A., Al-Ali, H., Powell, S. K., Brown, P. T., Volmar, C. H., Foster, T. C., Zeier, Z. R. & Wahlestedt, C. R., Jan 23 2019, In : Journal of Neuroscience. 39, 4, p. 612-626 15 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Brain-Derived Neurotrophic Factor
Histone Deacetylase Inhibitors
Messenger RNA

A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease

Timmons, J. A., Atherton, P. J., Larsson, O., Sood, S., Blokhin, I. O., Brogan, R. J., Volmar, C. H., Josse, A. R., Slentz, C., Wahlestedt, C. R., Phillips, S. M., Phillips, B. E., Gallagher, I. J. & Kraus, W. E., Jan 1 2018, In : Nucleic Acids Research. 46, 15, p. 7772-7792 21 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Insulin Resistance
Genome-Wide Association Study

BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT

Copsel, S. N., Lightbourn, C. O., Barreras, H., Lohse, I., Wolf, D., Bader, C. S., Manov, J., Kale, B. J., Shah, D., Brothers, S. P., Perez, V. L., Komanduri, K. V., Wahlestedt, C. R. & Levy, R. B., Jan 1 2018, In : Frontiers in immunology. 9, 1 p.

Research output: Contribution to journalArticle

Open Access
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Regulatory T-Lymphocytes
1 Citations (Scopus)

Cocaine exposure increases blood pressure and aortic stiffness via the mir-30c-5p-malic enzyme 1-reactive oxygen species pathway

Zhu, W., Wang, H., Wei, J., Sartor, G., Bao, M. M., Pierce, C. T., Wahlestedt, C. R., Dykxhoorn, D. M. & Dong, C., Jan 1 2018, In : Hypertension. 71, 4, p. 752-760 9 p.

Research output: Contribution to journalArticle

malate dehydrogenase (decarboxylating)
Vascular Stiffness
Reactive Oxygen Species
Blood Pressure

Developments in lncRNA drug discovery: where are we heading?

Blokhin, I., Khorkova, O., Hsiao, J. & Wahlestedt, C. R., Sep 2 2018, In : Expert Opinion on Drug Discovery. 13, 9, p. 837-849 13 p.

Research output: Contribution to journalReview article

Long Noncoding RNA
Drug Discovery
Clustered Regularly Interspaced Short Palindromic Repeats
Expert Testimony