Claes R Wahlestedt


  • 24190 Citations
1976 …2021
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  • 11 Similar Profiles
Neuropeptide Y Medicine & Life Sciences
Long Noncoding RNA Medicine & Life Sciences
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Untranslated RNA Medicine & Life Sciences
Neuropeptide Y Receptors Medicine & Life Sciences
Small Interfering RNA Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Brain Medicine & Life Sciences

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Projects 1976 2021

Epigenetic Signaling Pathways Contributing to Alcohol Dependence

Wahlestedt, C. R. & Heilig, M. A.

National Institutes of Health


Project: Research projectResearch Project

Drinking Behavior

Role of MicroRNAs in the Mechanisms of Drug Dependence

Wahlestedt, C. R. & Kenny, P.

National Institutes of Health


Project: Research projectResearch Project

Substance-Related Disorders
Neuronal Plasticity

Long noncoding RNAs and chromatin regulation in cocaine addiction

Wahlestedt, C. R.

National Institutes of Health


Project: Research projectExploratory/Developmental Grants

Long Noncoding RNA
Cocaine-Related Disorders
Self Administration
Antisense RNA
Brain-Derived Neurotrophic Factor
Untranslated RNA
Rett Syndrome
Cocaine-Related Disorders
Substance-Related Disorders
nociceptin receptor

Research Output 1982 2018

A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease

Timmons, J. A., Atherton, P. J., Larsson, O., Sood, S., Blokhin, I. O., Brogan, R. J., Volmar, C. H., Josse, A. R., Slentz, C., Wahlestedt, C. R., Phillips, S. M., Phillips, B. E., Gallagher, I. J. & Kraus, W. E., Jan 1 2018, In : Nucleic acids research. 46, 15, p. 7772-7792 21 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Insulin Resistance
Genome-Wide Association Study
1 Citations

Cocaine exposure increases blood pressure and aortic stiffness via the mir-30c-5p-malic enzyme 1-reactive oxygen species pathway

Zhu, W., Wang, H., Wei, J., Sartor, G., Bao, M. M., Pierce, C. T., Wahlestedt, C. R., Dykxhoorn, D. M. & Dong, C., Jan 1 2018, In : Hypertension. 71, 4, p. 752-760 9 p.

Research output: Contribution to journalArticle

malate dehydrogenase (decarboxylating)
Vascular Stiffness
Reactive Oxygen Species
Blood Pressure

Developments in lncRNA drug discovery: where are we heading?

Blokhin, I., Khorkova, O., Hsiao, J. & Wahlestedt, C. R., Sep 2 2018, In : Expert Opinion on Drug Discovery. 13, 9, p. 837-849 13 p.

Research output: Contribution to journalReview article

Long Noncoding RNA
Drug Discovery
Clustered Regularly Interspaced Short Palindromic Repeats
Expert Testimony

Drug and disease signature integration identifies synergistic combinations in glioblastoma

Stathias, V., Jermakowicz, A. M., Maloof, M. E., Forlin, M., Walters, W., Suter, R. K., Durante, M. A., Williams, S. L., Harbour, J. W., Volmar, C. H., Lyons, N. J., Wahlestedt, C. R., Graham, R. M., Ivan, M. E., Komotar, R. J., Sarkaria, J. N., Subramanian, A., Golub, T. R., Schuerer, S. C. & Ayad, N., Dec 1 2018, In : Nature communications. 9, 1, 5315.

Research output: Contribution to journalArticle

Gene expression

Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma

Lohse, I., Al-Ali, H., Volmar, C. H., Alvarez Trotta, A. D., Brothers, S. P., Capobianco, A. J. & Wahlestedt, C. R., Sep 1 2018, In : PloS one. 13, 9, e0203173.

Research output: Contribution to journalArticle

Drug Repositioning
esophageal neoplasms