Carlos Singer, M.D., Central University of Venezuela School of Medicine, 1972

Professor

  • 6516 Citations
1989 …2019
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Research Output 1989 2019

2019

77 Long-term Valbenazine Treatment in Patients with Schizophrenia/Schizoaffective Disorder or Mood Disorder and Tardive Dyskinesia

Lindenmayer, J. P., Marder, S. R., Singer, C., Comella, C., Farahmand, K., Burke, J., Jimenez, R. & Siegert, S., Feb 1 2019, In : CNS spectrums. 24, 1, p. 214-215 2 p.

Research output: Contribution to journalArticle

Open Access
Mood Disorders
Psychotic Disorders
Schizophrenia
Psychiatry
Depression

Gender Disparities in Deep Brain Stimulation for Parkinson's Disease

Shpiner, D. S., Di Luca, D. G., Cajigas, I., Diaz, J. S., Margolesky, J., Moore, H. P., Levin, B. E., Singer, C., Jagid, J. & Luca, C. C., Jun 1 2019, In : Neuromodulation. 22, 4, p. 484-488 5 p.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Parkinson Disease
Lost to Follow-Up
Patient Preference
Analysis of Variance

Hemodynamic responses to an exercise stress test in Parkinson’s disease patients without orthostatic hypotension

Roberson, K. B., Signorile, J., Singer, C., Jacobs, K., Eltoukhy, M. M., Ruta, N., Mazzei, N. & Buskard, A. N. L., Jan 1 2019, In : Applied Physiology, Nutrition and Metabolism. 44, 7, p. 751-758 8 p.

Research output: Contribution to journalArticle

Orthostatic Hypotension
Exercise Test
Parkinson Disease
Hemodynamics
Exercise

Motivations for participation in Parkinson disease genetic research among hispanics versus non-hispanics

Nuytemans, K., Manrique, C. P., Uhlenberg, A., Scott, W. K., Cuccaro, M., Luca, C. C., Singer, C. & Vance, J. M., Jan 1 2019, In : Frontiers in Genetics. 10, JUN, 658.

Research output: Contribution to journalComment/debate

Open Access
Genetic Research
Hispanic Americans
Parkinson Disease
Research

Revisiting eligibility for deep brain stimulation: Do preoperative mood symptoms predict outcomes in Parkinson's disease patients?

Sarno, M., Gaztanaga, W., Banerjee, N., Bure-Reyes, A., Rooks, J., Margolesky, J., Luca, C. C., Singer, C., Moore, H. P., Jagid, J. & Levin, B., Jan 1 2019, In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Parkinson Disease
Anxiety
Depression
Cognition
1 Citation (Scopus)

Tandem gait abnormality in Parkinson disease: Prevalence and implication as a predictor of fall risk

Margolesky, J., Bette, S., Shpiner, D. S., Jordan, E. A., Dong, C., Rundek, T., Luca, C. C., Moore, H. P. & Singer, C., Jan 1 2019, In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

Gait
Parkinson Disease
Methylenebis(chloroaniline)
Freezing
England

Teaching NeuroImages: Severe spasms resembling status dystonicus as an unusual presentation of stiff-person syndrome

Di Luca, D. G., Bette, S., Singer, C. & Luca, C. C., Feb 12 2019, In : Neurology. 92, 7, p. e748

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Spasm
Teaching

The Parkinson's Disease Sleep Scale–2 (PDSS-2): Validation of the Spanish Version and Its Relationship With a Roommate-Based Version

Martinez-Martin, P., Wetmore, J. B., Rodríguez-Blázquez, C., Arakaki, T., Bernal, O., Campos-Arillo, V., Cerda, C., Estrada-Bellmann, I., Garretto, N., Ginsburg, L., Máñez-Miró, J. U., Martínez-Castrillo, J. C., Pedroso, I., Serrano-Dueñas, M., Singer, C., Rodríguez-Violante, M. & Vivancos, F., Jan 1 2019, In : Movement Disorders Clinical Practice.

Research output: Contribution to journalArticle

Parkinson Disease
Sleep
Proxy
Reproducibility of Results

Treatment of hemifacial spasm

Singer, C., Jan 1 2019, Current Clinical Neurology. Humana Press Inc., p. 327-328 2 p. (Current Clinical Neurology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Hemifacial Spasm
Synkinesis
Blepharospasm
Bell Palsy
Surgical Decompression
2018

A Co-occurrence of Trinucleotide Repeat Disorders

Margolesky, J., Starosta-Rubenstein, S., Verma, A. & Singer, C., Jan 1 2018, (Accepted/In press) In : Movement Disorders Clinical Practice.

Research output: Contribution to journalArticle

Trinucleotide Repeats
2 Citations (Scopus)

Author Correction to: Pooled Analyses of Phase III Studies of ADS-5102 (Amantadine) Extended-Release Capsules for Dyskinesia in Parkinson’s Disease

Elmer, L. W., Juncos, J. L., Singer, C., Truong, D. D., Criswell, S. R., Parashos, S., Felt, L., Johnson, R. & Patni, R., Apr 10 2018, (Accepted/In press) In : CNS Drugs. p. 1-2 2 p.

Research output: Contribution to journalArticle

Amantadine
Dyskinesias
Capsules
Parkinson Disease
3 Citations (Scopus)

Dancing Dorsal Quadrilaterals: A Novel Peripherally Induced Movement Disorder

Lizarraga, K. J., Thompson, P. D., Moore, H. P., Mizraji, G., Gershanik, O. S., Singer, C. & Lang, A. E., Jan 1 2018, (Accepted/In press) In : JAMA Neurology. p. E1-E4

Research output: Contribution to journalArticle

Dancing
Movement Disorders
Dyskinesias
Neuralgia
Spine
4 Citations (Scopus)

Extended-release oral capsule of carbidopa-levodopa in parkinson disease

Margolesky, J. & Singer, C., Jan 1 2018, In : Therapeutic Advances in Neurological Disorders. 11

Research output: Contribution to journalReview article

Levodopa
Capsules
Parkinson Disease
Pharmacokinetics
Safety

It is dopey to stop giving dopamine to hospitalized patients with Parkinson’s disease

Margolesky, J. & Singer, C., Jan 2 2018, In : Expert Review of Neurotherapeutics. 18, 1, p. 1-3 3 p.

Research output: Contribution to journalEditorial

Parkinson Disease
Dopamine
9 Citations (Scopus)

Pooled Analyses of Phase III Studies of ADS-5102 (Amantadine) Extended-Release Capsules for Dyskinesia in Parkinson’s Disease

Elmer, L. W., Juncos, J. L., Singer, C., Truong, D. D., Criswell, S. R., Parashos, S., Felt, L., Johnson, R. & Patni, R., Mar 12 2018, (Accepted/In press) In : CNS Drugs. p. 1-12 12 p.

Research output: Contribution to journalArticle

Amantadine
Dyskinesias
Capsules
Parkinson Disease
Placebos
6 Citations (Scopus)

Relationship between the MDS-UPDRS and Quality of Life: A large multicenter study of 3206 patients

Skorvanek, M., Martinez-Martin, P., Kovacs, N., Zezula, I., Rodriguez-Violante, M., Corvol, J. C., Taba, P., Seppi, K., Levin, O., Schrag, A., Aviles-Olmos, I., Alvarez-Sanchez, M., Arakaki, T., Aschermann, Z., Benchetrit, E., Benoit, C., Bergareche-Yarza, A., Cervantes-Arriaga, A., Chade, A., Cormier, F. & 25 others, Datieva, V., Gallagher, D. A., Garretto, N., Gdovinova, Z., Gershanik, O., Grofik, M., Han, V., Kadastik-Eerme, L., Kurtis, M. M., Mangone, G., Martinez-Castrillo, J. C., Mendoza-Rodriguez, A., Minar, M., Moore, H. P., Muldmaa, M., Mueller, C., Pinter, B., Poewe, W., Rallmann, K., Reiter, E., Rodriguez-Blazquez, C., Singer, C., Valkovic, P., Goetz, C. G. & Stebbins, G. T., Jan 1 2018, (Accepted/In press) In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

Multicenter Studies
Quality of Life
Apathy
Bandages
Fatigue
5 Citations (Scopus)
Levodopa
Parkinson Disease
Disease
management
evidence
2017
28 Citations (Scopus)

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease

McGarry, A., McDermott, M., Kieburtz, K., DeBlieck, E. A., Beal, F., Marder, K., Ross, C., Shoulson, I., Gilbert, P., Mallonee, W. M., Guttman, M., Wojcieszek, J., Kumar, R., LeDoux, M. S., Jenkins, M., Rosas, H. D., Nance, M., Biglan, K., Como, P., Dubinsky, R. M. & 40 others, Shannon, K. M., O'Suilleabhain, P., Chou, K., Walker, F., Martin, W., Wheelock, V. L., McCusker, E., Jankovic, J., Singer, C., Sanchez-Ramos, J., Scott, B., Suchowersky, O., Factor, S. A., Higgins, D. S., Molho, E., Revilla, F., Caviness, J. N., Friedman, J. H., Perlmutter, J. S., Feigin, A., Anderson, K., Rodriguez, R., McFarland, N. R., Margolis, R. L., Farbman, E. S., Raymond, L. A., Suski, V., Kostyk, S., Colcher, A., Seeberger, L., Epping, E., Esmail, S., Diaz, N., Alan Fung, W. L., Diamond, A., Frank, S., Hanna, P., Hermanowicz, N., Dure, L. S. & Cudkowicz, M., Jan 10 2017, In : Neurology. 88, 2, p. 152-159 8 p.

Research output: Contribution to journalArticle

coenzyme Q10
Huntington Disease
Placebos
Medical Futility
Canada
5 Citations (Scopus)

Association of metabolic syndrome and change in Unified Parkinson's Disease Rating Scale scores

Leehey, M., Luo, S., Sharma, S., Wills, A. M. A., Bainbridge, J. L., Wong, P. S., Simon, D. K., Schneider, J., Zhang, Y., Pérez, A., Dhall, R., Christine, C. W., Singer, C., Cambi, F. & Boyd, J. T., Oct 24 2017, In : Neurology. 89, 17, p. 1789-1794 6 p.

Research output: Contribution to journalArticle

Parkinson Disease
National Institute of Neurological Disorders and Stroke
Creatine
Random Allocation
Uric Acid
3 Citations (Scopus)

Autonomic and electrocardiographic findings in Parkinson's disease

Gibbons, C. H., Simon, D. K., Huang, M., Tilley, B., Aminoff, M. J., Bainbridge, J. L., Brodsky, M., Freeman, R., Goudreau, J., Hamill, R. W., Luo, S. T., Singer, C., Videnovic, A., Bodis-Wollner, I. & Wong, P. S., Jul 1 2017, In : Autonomic Neuroscience: Basic and Clinical. 205, p. 93-98 6 p.

Research output: Contribution to journalArticle

Parkinson Disease
Heart Rate
Electrocardiography
Longitudinal Studies
Disease Progression
7 Citations (Scopus)

Caffeine, creatine, GRIN2A and Parkinson's disease progression

Simon, D. K., Wu, C., Tilley, B. C., Lohmann, K., Klein, C., Payami, H., Wills, A. M., Aminoff, M. J., Bainbridge, J., Dewey, R., Hauser, R. A., Schaake, S., Schneider, J. S., Sharma, S., Singer, C., Tanner, C. M., Truong, D., Wei, P., Wong, P. S. & Yang, T., Apr 15 2017, In : Journal of the Neurological Sciences. 375, p. 355-359 5 p.

Research output: Contribution to journalArticle

Creatine
Caffeine
Parkinson Disease
Disease Progression
Genotype

Dalfampridine in Parkinson's disease related gait dysfunction: A randomized double blind trial

Luca, C. C., Nadayil, G., Dong, C., Nahab, F. B., Field-Fote, E. & Singer, C., Aug 15 2017, In : Journal of the Neurological Sciences. 379, p. 7-11 5 p.

Research output: Contribution to journalArticle

Gait
Parkinson Disease
Placebos
Walking
Potassium Channel Blockers
3 Citations (Scopus)

Design of a cluster-randomized minority recruitment trial: RECRUIT

Tilley, B. C., Mainous, A. G., Smith, D. W., McKee, M. D., Amorrortu, R. P., Alvidrez, J., Diaz, V., Ford, M. E., Fernandez, M. E., Hauser, R. A., Singer, C., Landa, V., Trevino, A., DeSantis, S. M., Zhang, Y., Daniels, E., Tabor, D. & Vernon, S. W., Jun 1 2017, In : Clinical Trials. 14, 3, p. 286-298 13 p.

Research output: Contribution to journalArticle

Physicians
Quality Improvement
Research Personnel
Clinical Trials
Ethnic Groups
10 Citations (Scopus)

Differences in MDS-UPDRS Scores Based on Hoehn and Yahr Stage and Disease Duration

Skorvanek, M., Martinez-Martin, P., Kovacs, N., Rodriguez-Violante, M., Corvol, J. C., Taba, P., Seppi, K., Levin, O., Schrag, A., Foltynie, T., Alvarez-Sanchez, M., Arakaki, T., Aschermann, Z., Aviles-Olmos, I., Benchetrit, E., Benoit, C., Bergareche-Yarza, A., Cervantes-Arriaga, A., Chade, A., Cormier, F. & 27 others, Datieva, V., Gallagher, D. A., Garretto, N., Gdovinova, Z., Gershanik, O., Grofik, M., Han, V., Huang, J., Kadastik-Eerme, L., Kurtis, M. M., Mangone, G., Martinez-Castrillo, J. C., Mendoza-Rodriguez, A., Minar, M., Moore, H. P., Muldmaa, M., Mueller, C., Pinter, B., Poewe, W., Rallmann, K., Reiter, E., Rodriguez-Blazquez, C., Singer, C., Tilley, B. C., Valkovic, P., Goetz, C. G. & Stebbins, G. T., Jul 1 2017, In : Movement Disorders Clinical Practice. 4, 4, p. 536-544 9 p.

Research output: Contribution to journalArticle

Movement Disorders
Parkinson Disease
Analysis of Variance
Cross-Sectional Studies
Demography
5 Citations (Scopus)

How tandem gait stumbled into the neurological exam: a review

Margolesky, J. & Singer, C., Sep 11 2017, (Accepted/In press) In : Neurological Sciences. p. 1-7 7 p.

Research output: Contribution to journalArticle

Gait
Cerebellar Diseases
Parkinsonian Disorders
Peripheral Nervous System Diseases
History
2 Citations (Scopus)

Insomnia, sleep quality, and quality of life in mild to moderate parkinson's disease

Shafazand, S., Wallace, D., Arheart, K., Vargas, S., Luca, C. C., Moore, H. P., Katzen, H., Levin, B. & Singer, C., Mar 1 2017, In : Annals of the American Thoracic Society. 14, 3, p. 412-419 8 p.

Research output: Contribution to journalArticle

Sleep Initiation and Maintenance Disorders
Obstructive Sleep Apnea
Parkinson Disease
Sleep
Quality of Life
12 Citations (Scopus)

Multicenter observational study of abobotulinumtoxinA neurotoxin in cervical dystonia: The ANCHOR-CD registry

Trosch, R. M., Espay, A. J., Truong, D., Gil, R., Singer, C., LeWitt, P. A., Lew, M. F., Tagliati, M., Adler, C. H., Chen, J. J., Marchese, D. & Comella, C. L., May 15 2017, In : Journal of the Neurological Sciences. 376, p. 84-90 7 p.

Research output: Contribution to journalArticle

Torticollis
Neurotoxins
Multicenter Studies
Observational Studies
Registries
21 Citations (Scopus)

National randomized controlled trial of virtual house calls for Parkinson disease

Connect.Parkinson Investigators, Sep 12 2017, In : Neurology. 89, 11, p. 1152-1161 10 p.

Research output: Contribution to journalArticle

House Calls
Parkinson Disease
Randomized Controlled Trials
Quality of Health Care
Quality of Life

Neurovascular uncoupling after rapid glycemic control as a trigger of the diabetic-uremic striatopallidal syndrome

Lizarraga, K. J., Adams, D., Judith Post, M., Skyler, J. S. & Singer, C., 2017, (Accepted/In press) In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

Rapid Eye Movement Sleep Behavior Disorder Manifesting as Sign Language in a Patient with Dementia with Lewy Bodies

Margolesky, J., C Luca, C. & Singer, C., Jul 1 2017, In : Movement Disorders Clinical Practice. 4, 4, p. 623-624 2 p.

Research output: Contribution to journalArticle

REM Sleep Behavior Disorder
Sign Language
Lewy Body Disease
1 Citation (Scopus)

Subthalamic nucleus deep brain stimulation for the treatment of secondary dystonia: A case series and review of literature

Margolesky, J., Schoen, N., Jermakowicz, W., Sur, S., Cajigas, I., Singer, C., Jagid, J. & Luca, C. C., Jul 1 2017, In : Brain Stimulation. 10, 4, p. 870-872 3 p.

Research output: Contribution to journalLetter

2016
20 Citations (Scopus)

Clinical-genetic associations in the Prospective Huntington at Risk Observational Study (PHAROS) implications for clinical trials

The Huntington Study Group PHAROS Investigators, Jan 1 2016, In : JAMA Neurology. 73, 1, p. 102-110 9 p.

Research output: Contribution to journalArticle

Cytosine
Guanine
Adenine
Huntington Disease
Observational Studies
65 Citations (Scopus)

Effect of deutetrabenazine on chorea among patients with huntington disease: A randomized clinical trial

Frank, S., Testa, C. M., Stamler, D., Kayson, E., Davis, C., Edmondson, M. C., Kinel, S., Leavitt, B., Oakes, D., O'Neill, C., Vaughan, C., Goldstein, J., Herzog, M., Snively, V., Whaley, J., Wong, C., Suter, G., Jankovic, J., Jimenez-Shahed, J., Hunter, C. & 78 others, Claassen, D. O., Roman, O. C., Sung, V., Smith, J., Janicki, S., Clouse, R., Saint-Hilaire, M., Hohler, A., Turpin, D., James, R. C., Rodriguez, R., Rizer, K., Anderson, K. E., Heller, H., Carlson, A., Criswell, S., Racett, B. A., Revilla, F. J., Nucifora, F., Margolis, R. L., Ong, M. J., Mendis, T., Mendis, N., Singer, C., Quesada, M., Paulsen, J. S., Brashers-Krug, T., Miller, A., Kerr, J., Dubinsky, R. M., Gray, C., Factor, S. A., Sperin, E., Molho, E., Eglow, M., Evans, S., Kumar, R., Reeves, C., Samii, A., Chouinard, S., Beland, M., Scott, B. L., Hickey, P. T., Esmail, S., Fung, W. L. A., Gibbons, C., Qi, L., Colcher, A., Hackmyer, C., McGarry, A., Klos, K., Gudesblatt, M., Fafard, L., Graffitti, L., Schneider, D. P., Dhall, R., Wojcieszek, J. M., La Faver, K., Duker, A., Neefus, E., Wilson-Perez, H., Shprecher, D., Wall, P., Blindauer, K. A., Wheeler, L., Boyd, J. T., Houston, E., Farbman, E. S., Agarwal, P., Eberly, S. W., Watts, A., Tariot, P. N., Feigin, A., Evans, S., Beck, C., Orme, C., Edicola, J. & Christopher, E., Jul 5 2016, In : JAMA - Journal of the American Medical Association. 316, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

Chorea
Huntington Disease
Randomized Controlled Trials
Placebos
Therapeutics
12 Citations (Scopus)

National Randomized Controlled Trial of Virtual House Calls for People with Parkinson's Disease: Interest and Barriers

Dorsey, E. R., Achey, M. A., Beck, C. A., Beran, D. B., Biglan, K. M., Boyd, C. M., Schmidt, P. N., Simone, R., Willis, A. W., Galifianakis, N. B., Katz, M., Tanner, C. M., Dodenhoff, K., Ziman, N., Aldred, J., Carter, J., Jimenez-Shahed, J., Hunter, C., Spindler, M., Mari, Z. & 33 others, Morgan, J. C., McLane, D., Hickey, P., Gauger, L., Richard, I. H., Bull, M. T., Mejia, N. I., Bwala, G., Nance, M., Shih, L., Anderson, L., Singer, C., Zadikoff, C., Okon, N., Feigin, A., Ayan, J., Vaughan, C., Pahwa, R., Cooper, J., Webb, S., Dhall, R., Hassan, A., Weis, D., Demello, S., Riggare, S. S., Wicks, P., Smith, J., Keenan, H. T., Korn, R., Schwarz, H., Sharma, S., Stevenson, E. A. & Zhu, W., Jul 1 2016, In : Telemedicine and e-Health. 22, 7, p. 590-598 9 p.

Research output: Contribution to journalArticle

House Calls
Parkinson Disease
Randomized Controlled Trials
Personnel Selection
Videoconferencing
2015
38 Citations (Scopus)

Assessing the non-motor symptoms of Parkinson's disease: MDS-UPDRS and NMS Scale

Martinez-Martin, P., Chaudhuri, K. R., Rojo-Abuin, J. M., Rodriguez-Blazquez, C., Alvarez-Sanchez, M., Arakaki, T., Bergareche-Yarza, A., Chade, A., Garretto, N., Gershanik, O., Kurtis, M. M., Martinez-Castrillo, J. C., Mendoza-Rodriguez, A., Moore, H. P., Rodriguez-Violante, M., Singer, C., Tilley, B. C., Huang, J., Stebbins, G. T. & Goetz, C. G., Jan 1 2015, In : European Journal of Neurology. 22, 1, p. 37-43 7 p.

Research output: Contribution to journalArticle

Movement Disorders
Parkinson Disease
Nonparametric Statistics
Cross-Sectional Studies
12 Citations (Scopus)

Caffeine and progression of Parkinson disease: A deleterious interaction with creatine

Simon, D. K., Wu, C., Tilley, B. C., Wills, A. M., Aminoff, M. J., Bainbridge, J., Hauser, R. A., Schneider, J. S., Sharma, S., Singer, C., Tanner, C. M., Truong, D. & Wong, P. S., Oct 1 2015, In : Clinical Neuropharmacology. 38, 5, p. 163-169 7 p.

Research output: Contribution to journalArticle

Creatine
Caffeine
Parkinson Disease
Movement Disorders
Canada
16 Citations (Scopus)

Conversion to IPX066 from standard levodopa formulations in advanced Parkinson's disease: experience in clinical trials

Nausieda, P. A., Hsu, A., Elmer, L., Gil, R. A., Spiegel, J., Singer, C., Khanna, S., Rubens, R., Kell, S., Modi, N. B. & Gupta, S., Nov 21 2015, In : Journal of Parkinson's Disease. 5, 4, p. 837-845 9 p.

Research output: Contribution to journalArticle

Levodopa
Parkinson Disease
Clinical Trials
Dyskinesias
levodopa drug combination carbidopa
89 Citations (Scopus)

Effect of creatine monohydrate on clinical progression in patients with parkinson disease: A randomized clinical trial

Kieburtz, K., Tilley, B. C., Elm, J. J., Babcock, D., Hauser, R., Ross, G. W., Augustine, A. H., Augustine, E. U., Aminoff, M. J., Bodis-Wollner, I. G., Boyd, J., Cambi, F., Chou, K., Christine, C. W., Cines, M., Dahodwala, N., Derwent, L., Dewey, R. B., Hawthorne, K., Houghton, D. J. & 23 others, Kamp, C., Leehey, M., Lew, M. F., Lin Liang, G. S., Luo, S. T., Mari, Z., Morgan, J. C., Parashos, S., Pérez, A., Petrovitch, H., Rajan, S., Reichwein, S., Roth, J. T., Schneider, J. S., Shannon, K. M., Simon, D. K., Simuni, T., Singer, C., Sudarsky, L., Tanner, C. M., Umeh, C. C., Williams, K. & Wills, A. M., Feb 10 2015, In : JAMA - Journal of the American Medical Association. 313, 6, p. 584-593 10 p.

Research output: Contribution to journalArticle

Creatine
Parkinson Disease
Randomized Controlled Trials
Placebos
National Institute of Neurological Disorders and Stroke
1 Citation (Scopus)

Impact of Depression on Progression of Impairment and Disability in Early Parkinson's Disease

the NET PD LS1 investigators, Dec 1 2015, In : Movement Disorders Clinical Practice. 2, 4, p. 371-378 8 p.

Research output: Contribution to journalArticle

Parkinson Disease
Depression
Equipment and Supplies
Disease Progression
Multivariate Analysis
83 Citations (Scopus)

Pioglitazone in early Parkinson's disease: A phase 2, multicentre, double-blind, randomised trial

Simuni, T., Kieburtz, K., Tilley, B., J Elm, J., Ravina, B., Babcock, D., Emborg, M., Hauser, R., Kamp, C., Morgan, J. C., Webster Ross, G., K Simon, D., Bainbridge, J., Baker, L., Bodis-Wollner, I., Boyd, J., Cambi, F., Carter, J., Chou, K., Dahodwala, N. & 28 others, Dewey, R. B., Dhall, R., Fang, J., Farrow, B., Feigin, A., Glazman, S., Goudreau, J., LeBlanc, P., Lee, S., Leehey, M., Lew, M. F., Lowenhaupt, S., Luo, S., Pahwa, R., Perez, A., Schneider, J., Scott, B., Shah, B., Shannon, K. M., Sharma, S., Singer, C., Truong, D., Wagner, R., Williams, K., Marie Wills, A., Shieen Wong, P., Zadikoff, C. & Zweig, R., Aug 1 2015, In : The Lancet Neurology. 14, 8, p. 795-803 9 p.

Research output: Contribution to journalArticle

pioglitazone
Parkinson Disease
Placebos
Medical Futility
Nitromifene
21 Citations (Scopus)

Randomized, controlled pilot trial of solifenacin succinate for overactive bladder in Parkinson's disease

Non-Motor Working Group of the Parkinson Study Group (PSG), May 1 2015, In : Parkinsonism and Related Disorders. 21, 5, p. 514-520 7 p.

Research output: Contribution to journalArticle

Overactive Urinary Bladder
Parkinson Disease
Randomized Controlled Trials
Urinary Incontinence
Nocturia
49 Citations (Scopus)

Safety, tolerability, and efficacy of PBT2 in Huntington's disease: A phase 2, randomised, double-blind, placebo-controlled trial

Huntington Study Group Reach2HD Investigators, Jan 1 2015, In : The Lancet Neurology. 14, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Huntington Disease
Placebos
Safety
Trail Making Test
Cognition
2014
134 Citations (Scopus)

A randomized clinical trial of high-dosage coenzyme Q10 in early parkinson disease no evidence of benefit

The Parkinson Study Group QE3 Investigators, 2014, In : JAMA Neurology. 75, 1, p. 543-552 10 p.

Research output: Contribution to journalArticle

coenzyme Q10
Parkinson Disease
Randomized Controlled Trials
Placebos
Tremor

Corrigendum to "Rapid eye movement sleep behavior disorder: Devising controlled active treatment studies for symptomatic and neuroprotective therapy-a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group" [Sleep Med 14(8) (2013) 795-806]

Schenck, C. H., Montplaisir, J. Y., Frauscher, B., Hogl, B., Gagnon, J. F., Postuma, R., Sonka, K., Jennum, P., Partinen, M., Arnulf, I., de Cock, V. C., Dauvilliers, Y., Luppi, P. H., Heidbreder, A., Mayer, G., Sixel-Döring, F., Trenkwalder, C., Unger, M., Young, P., Wing, Y. K. & 19 others, Ferini-Strambi, L., Ferri, R., Plazzi, G., Zucconi, M., Inoue, Y., Iranzo, A., Santamaria, J., Bassetti, C., Möller, J. C., Boeve, B. F., Lai, Y. Y., Pavlova, M., Saper, C., Schmidt, P., Siegel, J. M., Singer, C., St Louis, E., Videnovic, A. & Oertel, W., Jan 1 2014, In : Sleep Medicine. 15, 1

Research output: Contribution to journalArticle

23 Citations (Scopus)

Relationship between the MDS-UPDRS domains and the health-related quality of life of Parkinson's disease patients

Martínez-Martín, P., Rodríguez-Blázquez, C., Forjaz, M. J., Álvarez-Sánchez, M., Arakaki, T., Bergareche-Yarza, A., Chade, A., Garretto, N., Gershanik, O., Kurtis, M. M., Martínez-Castrillo, J. C., Mendoza-Rodríguez, A., Moore, H. P., Rodríguez-Violante, M., Singer, C., Tilley, B. C., Huang, J., Stebbins, G. T. & Goetz, C. G., Mar 1 2014, In : European Journal of Neurology. 21, 3, p. 519-524 6 p.

Research output: Contribution to journalArticle

Movement Disorders
Parkinson Disease
Quality of Life
Linear Models
Nonparametric Statistics
12 Citations (Scopus)

Severity of depression and anxiety are predictors of response to antidepressant treatment in Parkinson's disease

Moonen, A. J. H., Wijers, A., Leentjens, A. F. G., Christine, C. W., Factor, S. A., Juncos, J., Lyness, J. M., Marsh, L., Panisset, M., Pfeiffer, R., Rottenberg, D., Serrano Ramos, C., Shulman, L., Singer, C., Slevin, J., McDonald, W., Auinger, P. & Richard, I. H., Jan 1 2014, In : Parkinsonism and Related Disorders. 20, 6, p. 644-646 3 p.

Research output: Contribution to journalArticle

Antidepressive Agents
Parkinson Disease
Anxiety
Depression
Placebos
2013
5 Citations (Scopus)

4-Aminopyridine improves freezing of gait in Parkinson's disease

Luca, C. C. & Singer, C., Oct 1 2013, In : Journal of Neurology. 260, 10, p. 2662-2664 3 p.

Research output: Contribution to journalArticle

Neurologic Gait Disorders
Potassium Channel Blockers
4-Aminopyridine
Gait
Freezing
17 Citations (Scopus)

An accelerometry-based study of lower and upper limb tremor in Parkinson's disease

Scanlon, B. K., Levin, B., Nation, D. A., Katzen, H. L., Guevara-Salcedo, A., Singer, C. & Papapetropoulos, S., Jun 1 2013, In : Journal of Clinical Neuroscience. 20, 6, p. 827-830 4 p.

Research output: Contribution to journalArticle

Accelerometry
Tremor
Parkinson Disease
Lower Extremity
Movement Disorders
6 Citations (Scopus)

Can 4-aminopyridine modulate dysfunctional gait networks in Parkinson's disease?

Luca, C. C. & Singer, C., Sep 1 2013, In : Parkinsonism and Related Disorders. 19, 9, p. 777-782 6 p.

Research output: Contribution to journalArticle

4-Aminopyridine
Gait
Parkinson Disease
Neurotransmitter Agents
Cerebellar Ataxia
162 Citations (Scopus)

Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder

Boeve, B. F., Silber, M. H., Ferman, T. J., Lin, S. C., Benarroch, E. E., Schmeichel, A. M., Ahlskog, J. E., Caselli, R. J., Jacobson, S., Sabbagh, M., Adler, C., Woodruff, B., Beach, T. G., Iranzo, A., Gelpi, E., Santamaria, J., Tolosa, E., Singer, C., Mash, D. C., Luca, C. C. & 11 others, Arnulf, I., Duyckaerts, C., Schenck, C. H., Mahowald, M. W., Dauvilliers, Y., Graff-Radford, N. R., Wszolek, Z. K., Parisi, J. E., Dugger, B., Murray, M. E. & Dickson, D. W., Aug 1 2013, In : Sleep Medicine. 14, 8, p. 754-762 9 p.

Research output: Contribution to journalArticle

REM Sleep Behavior Disorder
Nervous System Diseases
Lewy Body Disease
Multiple System Atrophy
Parkinsonian Disorders