Camillo Ricordi

Professor

  • 30687 Citations
1980 …2020

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Article
2020

Conformal Coating of Stem Cell-Derived Islets for β Cell Replacement in Type 1 Diabetes

Stock, A. A., Manzoli, V., De Toni, T., Abreu, M. M., Poh, Y. C., Ye, L., Roose, A., Pagliuca, F. W., Thanos, C., Ricordi, C. & Tomei, A. A., Jan 14 2020, In : Stem Cell Reports. 14, 1, p. 91-104 14 p.

Research output: Contribution to journalArticle

Open Access

Mesenchymal stem cells ameliorate β cell dysfunction of human type 2 diabetic islets by reversing β cell dedifferentiation

Wang, L., Liu, T., Liang, R., Wang, G., Liu, Y., Zou, J., Liu, N., Zhang, B., Liu, Y., Ding, X., Cai, X., Wang, Z., Xu, X., Ricordi, C., Wang, S. & Shen, Z., Jan 2020, In : EBioMedicine. 51, 102615.

Research output: Contribution to journalArticle

Open Access

Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche

Qadir, M. M. F., Álvarez-Cubela, S., Klein, D., van Dijk, J., Muñiz-Anquela, R., Moreno-Hernández, Y. B., Lanzoni, G., Sadiq, S., Navarro-Rubio, B., García, M. T., Díaz, Á., Johnson, K., Sant, D., Ricordi, C., Griswold, A., Pastori, R. L. & Domínguez-Bendala, J., May 19 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 20, p. 10876-10887 12 p.

Research output: Contribution to journalArticle

Open Access

The Effect of Recovery Warm-up Time Following Cold Storage on the Dynamic Glucose-stimulated Insulin Secretion of Isolated Human Islets

Alcazar, O., Alvarez, A., Ricordi, C., Linetsky, E. & Buchwald, P., Jan 1 2020, In : Cell transplantation. 29, p. 963689720908278

Research output: Contribution to journalArticle

Open Access
2019

A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells

Qadir, M. M. F., Álvarez-Cubela, S., Belle, K., Sapir, T., Messaggio, F., Johnson, K. B., Umland, O., Hardin, D., Klein, D., Pérez-Álvarez, I., Sadiq, F., Alcázar, O., Inverardi, L. A., Ricordi, C., Buchwald, P., Fraker, C. A., Pastori, R. L. & Domínguez-Bendala, J., Mar 5 2019, In : Stem Cell Reports. 12, 3, p. 611-623 13 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice

Abdulreda, M. H., Molano, R., Faleo, G., Lopez-Cabezas, M., Shishido, A., Ulissi, U., Fotino, C., Hernandez, L. F., Tschiggfrie, A., Aldrich, V. R., Tamayo-Garcia, A., Bayer, A. S., Ricordi, C., Caicedo, A., Buchwald, P., Pileggi, A. & Berggren, P-O. Y., Jul 1 2019, In : Diabetologia. 62, 7, p. 1237-1250 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Operational immune tolerance towards transplanted allogeneic pancreatic islets in mice and a non-human primate

Abdulreda, M. H., Berman, D. M., Shishido, A., Martin, C., Hossameldin, M., Tschiggfrie, A., Hernandez, L. F., Hernandez, A., Ricordi, C., Parel, J. M., Jankowska-Gan, E., Burlingham, W. J., Arrieta-Quintero, E. A., Perez Quinones, V. L., Kenyon, N. S. & Berggren, P-O. Y., May 1 2019, In : Diabetologia. 62, 5, p. 811-821 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Serum copper profile in patients with type 1 diabetes in comparison to other metals

Squitti, R., Negrouk, V., Perera, M., Llabre, M. M., Ricordi, C., Rongioletti, M. C. A. & Mendez, A. J., Dec 1 2019, In : Journal of Trace Elements in Medicine and Biology. 56, p. 156-161 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

The role of vitamin D and omega-3 PUFAs in islet transplantation

Infante, M., Ricordi, C., Padilla, N., Alvarez, A., Linetsky, E., Lanzoni, G., Mattina, A., Bertuzzi, F., Fabbri, A., Baidal, D. & Alejandro, R., Dec 2019, In : Nutrients. 11, 12, 2937.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

VITAL study: An incomplete picture?

Infante, M., Ricordi, C., Baidal, D. A., Alejandro, R., Lanzoni, G., Sears, B., Caprio, M. & Fabbri, A., Jan 1 2019, In : European review for medical and pharmacological sciences. 23, 7, p. 3142-3147 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Vitamin D and ω-3 Supplementations in Mediterranean Diet During the 1st Year of Overt Type 1 Diabetes: A Cohort Study

Cadario, F., Pozzi, E., Rizzollo, S., Stracuzzi, M., Beux, S., Giorgis, A., Carrera, D., Fullin, F., Riso, S., Rizzo, A. M., Montorfano, G., Bagnati, M., Dianzani, U., Caimmi, P., Bona, G. & Ricordi, C., Sep 9 2019, In : Nutrients. 11, 9

Research output: Contribution to journalArticle

Open Access
2018

Administration of Vitamin D and high dose of omega 3 to sustain remission of type 1 diabetes

Cadario, F., Savastio, S., Ricotti, R., Rizzo, A. M., Carrera, D., Maiuri, L. & Ricordi, C., Jan 1 2018, In : European review for medical and pharmacological sciences. 22, 2, p. 512-515 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Carnosine protects pancreatic beta cells and islets against oxidative stress damage

Miceli, V., Pampalone, M., Frazziano, G., Grasso, G., Rizzarelli, E., Ricordi, C., Casu, A., Iannolo, G. & Conaldi, P. G., Jan 1 2018, (Accepted/In press) In : Molecular and Cellular Endocrinology.

Research output: Contribution to journalArticle

11 Scopus citations

Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation

Miki, A., Ricordi, C., Sakuma, Y., Yamamoto, T., Misawa, R., Mita, A., Molano, R. D., Vaziri, N. D., Pileggi, A. & Ichii, H., May 2018, In : PloS one. 13, 5, e0196570.

Research output: Contribution to journalArticle

10 Scopus citations

Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke

Kerr, N., García-Contreras, M., Abbassi, S., Mejias, N. H., Desousa, B. R., Ricordi, C., Dietrich, W. D., Keane, R. W. & de Rivero Vaccari, J. P., Sep 4 2018, In : Frontiers in Molecular Neuroscience. 11, 309.

Research output: Contribution to journalArticle

14 Scopus citations

Insulin-mimetic effects of short-term rapamycin in type 1 diabetic patients prior to islet transplantation

Benedini, S., Ermetici, F., Briganti, S., Codella, R., Terruzzi, I., Maffi, P., Caldara, R., Secchi, A., Nano, R., Piemonti, L., Alejandro, R., Ricordi, C. & Luzi, L., Apr 13 2018, (Accepted/In press) In : Acta Diabetologica. p. 1-8 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Islet-derived EATP fuels autoreactive CD8 + T cells and facilitates the onset of type 1 diabetes

Tezza, S., Nasr, M. B., D'Addio, F., Vergani, A., Usuelli, V., Falzoni, S., Bassi, R., Dellepiane, S., Fotino, C., Rossi, C., Maestroni, A., Solini, A., Corradi, D., Giani, E., Mameli, C., Bertuzzi, F., Pezzolesi, M. G., Wasserfall, C. H., Atkinson, M. A., Füchtbauer, E. M. & 7 others, Ricordi, C., Folli, F., Virgilio, F. D., Pileggi, A., Dhe-Paganon, S., Zuccotti, G. V. & Fiorina, P., Oct 1 2018, In : Diabetes. 67, 10, p. 2038-2053 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

Islet-Like Structures Generated In Vitro from Adult Human Liver Stem Cells Revert Hyperglycemia in Diabetic SCID Mice

Navarro-Tableros, V., Gai, C., Gomez, Y., Giunti, S., Pasquino, C., Deregibus, M. C., Tapparo, M., Pitino, A., Tetta, C., Brizzi, M. F., Ricordi, C. & Camussi, G., Jan 1 2018, (Accepted/In press) In : Stem Cell Reviews and Reports.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolomic changes in human adipose tissue derived products following non-enzymatic microfacturing

Garcia-Contreras, M., Messaggio, F., Mendez, A. J. & Ricordi, C., Jan 1 2018, In : European Review for Medical and Pharmacological Sciences. 22, 10, p. 3249-3260 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin-diabetic non-human primates

Safley, S. A., Kenyon, N. S., Berman-Weinberg, D., Barber, G. F., Willman, M., Duncanson, S., Iwakoshi, N., Holdcraft, R., Gazda, L., Thompson, P., Badell, I. R., Sambanis, A., Ricordi, C. & Weber, C. J., Jan 1 2018, (Accepted/In press) In : Xenotransplantation.

Research output: Contribution to journalArticle

17 Scopus citations

Omega-3 PUFAs and vitamin D co-supplementation as a safe-effective therapeutic approach for core symptoms of autism spectrum disorder: case report and literature review

Infante, M., Sears, B., Rizzo, A. M., Mariani Cerati, D., Caprio, M., Ricordi, C. & Fabbri, A., Jan 1 2018, (Accepted/In press) In : Nutritional Neuroscience.

Research output: Contribution to journalArticle

5 Scopus citations

P2RY1/ALK3-Expressing Cells within the Adult Human Exocrine Pancreas Are BMP-7 Expandable and Exhibit Progenitor-like Characteristics

Qadir, M. M. F., Álvarez-Cubela, S., Klein, D., Lanzoni, G., García-Santana, C., Montalvo, A., Pláceres-Uray, F., Mazza, E. M. C., Ricordi, C., Inverardi, L. A., Pastori, R. & Dominguez-Bendala, J., Feb 27 2018, In : Cell Reports. 22, 9, p. 2455-2468 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

Rodriguez-Diaz, R., Molano, R., Weitz, J. R., Abdulreda, M. H., Berman, D. M., Leibiger, B., Leibiger, I. B., Kenyon, N. S., Ricordi, C., Pileggi, A., Caicedo, A. & Berggren, P-O. Y., Mar 6 2018, In : Cell Metabolism. 27, 3, p. 549-558.e4

Research output: Contribution to journalArticle

36 Scopus citations
2017

Active subjects with autoimmune type 1 diabetes have better metabolic profiles than sedentary controls

Adamo, M., Codella, R., Casiraghi, F., Ferrulli, A., Macrì, C., Bazzigaluppi, E., Terruzzi, I., Inverardi, L. A., Ricordi, C. & Luzi, L., 2017, In : Cell Transplantation. 26, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Can Type 1 diabetes progression be halted? Possible role of high dose vitamin D and omega 3 fatty acids

Cadario, F., Savastio, S., Rizzo, A. M., Carrera, D., Bona, G. & Ricordi, C., Apr 1 2017, In : European Review for Medical and Pharmacological Sciences. 21, 7, p. 1604-1609 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Comprehensive metabolomics study to assess longitudinal biochemical changes and potential early biomarkers in nonobese diabetic mice that progress to diabetes

Buchwald, P., Tamayo-Garcia, A., Ramamoorthy, S., Garcia-Contreras, M., Mendez, A. J. & Ricordi, C., Oct 6 2017, In : Journal of Proteome Research. 16, 10, p. 3873-3890 18 p.

Research output: Contribution to journalArticle

5 Scopus citations

Diabetes and Alzheimer's Disease: Can Elevated Free Copper Predict the Risk of the Disease?

Squitti, R., Mendez, A. J., Simonelli, I. & Ricordi, C., 2017, In : Journal of Alzheimer's Disease. 56, 3, p. 1055-1064 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Does the Mesenchymal Stem Cell Source Influence Smooth Muscle Regeneration in Tissue-Engineered Urinary Bladders?

Pokrywczynska, M., Jundzill, A., Warda, K., Buchholz, L., Rasmus, M., Adamowicz, J., Bodnar, M., Marszalek, A., Helmin-Basa, A., Michalkiewicz, J., Gagat, M., Grzanka, A., Frontczak-Baniewicz, M., Gastecka, A. M., Kloskowski, T., Nowacki, M., Ricordi, C. & Drewa, T., Nov 1 2017, In : Cell Transplantation. 26, 11, p. 1780-1791 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Engineering human renal epithelial cells for transplantation in regenerative medicine

Manzoli, V., Colter, D. C., Dhanaraj, S., Fornoni, A., Ricordi, C., Pileggi, A. & Tomei, A. A., Oct 2017, In : Medical Engineering and Physics. 48, p. 3-13 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol

Manzoli, V., Villa, C., Bayer, A. L., Morales, L. C., Molano, R., Torrente, Y., Ricordi, C., Hubbell, J. A. & Tomei, A. A., Jan 1 2017, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

20 Scopus citations

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

Garcia-Contreras, M., Tamayo-Garcia, A., Pappan, K. L., Michelotti, G. A., Stabler, C., Ricordi, C. & Buchwald, P., Jun 2 2017, In : Journal of Proteome Research. 16, 6, p. 2294-2306 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes

Garcia-Contreras, M., Shah, S. H., Tamayo, A., Robbins, P. D., Golberg, R. B., Mendez, A. J. & Ricordi, C., Dec 1 2017, In : Scientific Reports. 7, 1, 5998.

Research output: Contribution to journalArticle

36 Scopus citations
2016

A multicenter study: North american islet donor score in donor pancreas selection for human islet isolation for transplantation

Wang, L. J., Kin, T., O’Gorman, D., Shapiro, A. M. J., Naziruddin, B., Takita, M., Levy, M. F., Posselt, A. M., Szot, G. L., Savari, O., Barbaro, B., McGarrigle, J., Yeh, C., Oberholzer, J., Lei, J., Chen, T., Lian, M., Markmann, J. F., Alvarez, A., Linetsky, E. & 16 others, Ricordi, C., Balamurugan, A. N., Loganathan, G., Wilhelm, J. J., Hering, B. J., Bottino, R., Trucco, M., Liu, C., Min, Z., Li, Y., Naji, A., Fernandez, L. A., Ziemelis, M., Danobeitia, J. S., Millis, J. M. & Witkowski, P., 2016, In : Cell Transplantation. 25, 8, p. 1515-1523 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Bioengineering the endocrine pancreas: Intraomental islet transplantation within a biologic resorbable scaffold

Berman, D. M., Molano, R., Fotino, C., Ulissi, U., Gimeno, J., Mendez, A. J., Kenyon, N. M., Kenyon, N. S., Andrews, D. M., Ricordi, C. & Pileggi, A., May 1 2016, In : Diabetes. 65, 5, p. 1350-1361 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

CD52-negative NK cells are abundant in the liver and less susceptible to alemtuzumab treatment

Hotta, R., Ohira, M., Matsuura, T., Muraoka, I., Tryphonopoulos, P., Fan, J., Tekin, A., Selvaggi, G., Levi, D., Ruiz, P., Ricordi, C., Vianna, R., Ohdan, H., Waldmann, H., Tzakis, A. G. & Nishida, S., Aug 2016, In : PloS one. 11, 8, e0161618.

Research output: Contribution to journalArticle

3 Scopus citations

Clinical pancreatic islet transplantation

Shapiro, A. M. J., Pokrywczynska, M. & Ricordi, C., Nov 11 2016, (Accepted/In press) In : Nature Reviews Endocrinology.

Research output: Contribution to journalArticle

174 Scopus citations
18 Scopus citations

Effects of Composition of Alginate-Polyethylene Glycol Microcapsules and Transplant Site on Encapsulated Islet Graft Outcomes in Mice

Villa, C., Manzoli, V., Abreu, M. M., Verheyen, C. A., Seskin, M., Najjar, M., Molano, R., Torrente, Y., Ricordi, C. & Tomei, A., Aug 12 2016, (Accepted/In press) In : Transplantation.

Research output: Contribution to journalArticle

19 Scopus citations

Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement

Markmann, J. F., Bartlett, S. T., Johnson, P., Korsgren, O., Hering, B. J., Scharp, D., Kay, T. W. H., Bromberg, J., Odorico, J. S., Weir, G. C., Bridges, N., Kandaswamy, R., Stock, P., Friend, P., Gotoh, M., Cooper, D. K. C., Park, C. G., O'Connell, P. J., Stabler, C., Matsumoto, S. & 14 others, Ludwig, B., Choudhary, P., Khovatchev, B., Rickels, M. R., Sykes, M., Wood, K., Kraemer, K., Hwa, A., Stanley, E., Ricordi, C., Zimmerman, M., Greenstein, J., Montanya, E. & Otonkoski, T., Jun 21 2016, In : Transplantation. 100, 7, p. e25-e31

Research output: Contribution to journalArticle

18 Scopus citations

Fully automated islet cell counter (ICC) for the assessment of islet mass, purity, and size distribution by digital image analysis

Buchwald, P., Bernal, A., Echeverri, F., Tamayo-Garcia, A., Linetsky, E. & Ricordi, C., 2016, In : Cell Transplantation. 25, 10, p. 1747-1761 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

G-CSF and exenatide might be associated with increased long-term survival of allogeneic pancreatic islet grafts

Zoso, A., Serafini, P., Lanzoni, G., Peixoto, E., Messinger, S., Mantero, A., Padilla-Téllez, N. D., Baidal, D. A., Alejandro, R., Ricordi, C. & Inverardi, L., Jun 2016, In : PloS one. 11, 6, e0157245.

Research output: Contribution to journalArticle

3 Scopus citations

Metformin restrains pancreatic duodenal homeobox-1 (PDX-1) function by inhibiting ERK signaling in pancreatic ductal adenocarcinoma

Zhou, G., Yu, J., Wang, A., Liu, S. H., Sinnett-Smith, J., Wu, J., Sanchez, R., Nemunaitis, J., Ricordi, C., Rozengurt, E. & Brunicardi, F. C., Jan 1 2016, In : Current Molecular Medicine. 16, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

National institutes of health-sponsored clinical islet transplantation consortium phase 3 trial: Manufacture of a complex cellular product at eight processing facilities

Ricordi, C., Goldstein, J. S., Balamurugan, A. N., Szot, G. L., Kin, T., Liu, C., Czarniecki, C. W., Barbaro, B., Bridges, N. D., Cano, J., Clarke, W. R., Eggerman, T. L., Hunsicker, L. G., Kaufman, D. B., Khan, A., Lafontant, D. E., Linetsky, E., Luo, X., Markmann, J. F., Naji, A. & 14 others, Korsgren, O., Oberholzer, J., Turgeon, N. A., Brandhorst, D., Friberg, A. S., Lei, J., Wang, L. J., Wilhelm, J. J., Willits, J., Zhang, X., Hering, B. J., Posselt, A. M., Stock, P. G. & Shapiro, A. M. J., Nov 2016, In : Diabetes. 65, 11, p. 3418-3428 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

Phase 3 trial of transplantation of human islets in type 1 diabetes complicated by severe hypoglycemia

Hering, B. J., Clarke, W. R., Bridges, N. D., Eggerman, T. L., Alejandro, R., Bellin, M. D., Chaloner, K., Czarniecki, C. W., Goldstein, J. S., Hunsicker, L. G., Kaufman, D. B., Korsgren, O., Larsen, C. P., Luo, X., Markmann, J. F., Naji, A., Oberholzer, J., Posselt, A. M., Rickels, M. R., Ricordi, C. & 5 others, Robien, M. A., Senior, P. A., James Shapiro, A. M., Stock, P. G. & Turgeon, N. A., Jul 1 2016, In : Diabetes care. 39, 7, p. 1230-1240 11 p.

Research output: Contribution to journalArticle

195 Scopus citations

Report from IPITA-TTS opinion leaders meeting on the future of β-cell replacement

Bartlett, S. T., Markmann, J. F., Johnson, P., Korsgren, O., Hering, B. J., Scharp, D., Kay, T. W. H., Bromberg, J., Odorico, J. S., Weir, G. C., Bridges, N., Kandaswamy, R., Stock, P., Friend, P., Gotoh, M., Cooper, D. K. C., Park, C. G., O'Connell, P., Stabler, C., Matsumoto, S. & 14 others, Ludwig, B., Choudhary, P., Kovatchev, B., Rickels, M. R., Sykes, M., Wood, K., Kraemer, K., Hwa, A., Stanley, E., Ricordi, C., Zimmerman, M., Greenstein, J., Montanya, E. & Otonkoski, T., 2016, In : Transplantation. 100, p. S1-S44

Research output: Contribution to journalArticle

35 Scopus citations

Umbilical Cord Mesenchymal Stromal Cell with Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion

Cai, J., Wu, Z., Xu, X., Liao, L., Chen, J., Huang, L., Wu, W., Luo, F., Wu, C., Pugliese, A., Pileggi, A., Ricordi, C. & Tan, J., Jan 2016, In : Diabetes care. 39, 1, p. 149-157 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
2015

BMP-7 induces adult human pancreatic exocrine-to-endocrine conversion

Klein, D., Álvarez-Cubela, S., Lanzoni, G., Vargas, N., Prabakar, K. R., Boulina, M., Ricordi, C., Inverardi, L. A., Pastori, R. & Dominguez-Bendala, J., Dec 1 2015, In : Diabetes. 64, 12, p. 4123-4134 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Controlled Release of Dexamethasone from Organosilicone Constructs for Local Modulation of Inflammation in Islet Transplantation

Weaver, J. D., Song, Y., Yang, E. Y., Ricordi, C., Pileggi, A., Buchwald, P. & Stabler, C., Aug 1 2015, In : Tissue Engineering - Part A. 21, 15-16, p. 2250-2261 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Development of an encapsulated stem cell-based therapy for diabetes

Tomei, A., Villa, C. & Ricordi, C., Sep 2 2015, In : Expert Opinion on Biological Therapy. 15, 9, p. 1321-1336 16 p.

Research output: Contribution to journalArticle

24 Scopus citations