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Brian Marples

Research Professor

  • 3860 Citations
1992 …2019
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Fingerprint Dive into the research topics where Brian Marples is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Radiation Medicine & Life Sciences
Radiation Tolerance Medicine & Life Sciences
dosage Physics & Astronomy
Radiotherapy Medicine & Life Sciences
Ionizing Radiation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
radiation tolerance Physics & Astronomy
DNA Damage Medicine & Life Sciences

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Research Output 1992 2019

3 Citations (Scopus)

Targeting glioblastoma stem cells with 2-deoxy-d-glucose (2-DG) potentiates radiation-induced unfolded protein response (UPR)

Shah, S. S., Rodriguez, G. A., Musick, A., Walters, W. M., de Cordoba, N., Barbarite, E., Marlow, M. M., Marples, B., Prince, J. S., Komotar, R. J., Vanni, S. & Graham, R. M., Feb 1 2019, In : Cancers. 11, 2, 159.

Research output: Contribution to journal › Article

Open Access
Unfolded Protein Response
Glioblastoma
Stem Cells
Radiation
Glucose
2 Citations (Scopus)

A designer bow-tie combination therapeutic platform: An approach to resistant cancer treatment by simultaneous delivery of cytotoxic and anti-inflammatory agents and radiation

Pathak, R. K., Basu, U., Ahmad, A., Sarkar, S., Kumar, A., Surnar, B., Ansari, S., Wilczek, K., Ivan, M. E., Marples, B., Kolishetti, N. & Dhar, S., Dec 1 2018, In : Biomaterials. 187, p. 117-129 13 p.

Research output: Contribution to journal › Article

Oncology
Antigens
Prostatic Neoplasms
Anti-Inflammatory Agents
Radiation
1 Citation (Scopus)

Dual blockade of PI3K and MEK in combination with radiation in head and neck cancer

Blas, K., Wilson, T. G., Tonlaar, N., Galoforo, S., Hana, A., Marples, B. & Wilson, G. D., Jun 1 2018, In : Clinical and Translational Radiation Oncology. 11, p. 1-10 10 p.

Research output: Contribution to journal › Article

Open Access
Mitogen-Activated Protein Kinase Kinases
Head and Neck Neoplasms
Phosphatidylinositol 3-Kinases
Radiation
Cell Line
4 Citations (Scopus)

Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection

Surnar, B., Basu, U., Banik, B., Ahmad, A., Marples, B., Kolishetti, N. & Dhar, S., Dec 26 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. E12333-E12342

Research output: Contribution to journal › Article

Nanotechnology
Nanoparticles
Membranes
Brain
Astrocytes

Reduction of Cisplatin-Induced Ototoxicity without Compromising Its Antitumor Activity

Surnar, B., Kolishetti, N., Basu, U., Ahmad, A., Goka, E., Marples, B., Kolb, D., Lippman, M. E. & Dhar, S., Nov 20 2018, In : Biochemistry. 57, 46, p. 6500-6513 14 p.

Research output: Contribution to journal › Article

Cisplatin
Prodrugs
Nausea
Drug Approval
DNA