• 2422 Citations
1987 …2018
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RNA Medicine & Life Sciences
Escherichia coli Medicine & Life Sciences
Exoribonucleases Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Transfer RNA Medicine & Life Sciences
Pseudouridine Medicine & Life Sciences
Proteins Medicine & Life Sciences
Purification Chemical Compounds

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Projects 2001 2013

Exoribonucleases
Ribonucleases
Ribonuclease III
RNA
Escherichia coli

AN UNDULATOR RESOURCE FOR STRUCTURAL BIOLOGY

Malhotra, A., Ealick, S., Lippard, S., Deacon, A., Drennan, C., Crane, B., Baker, T., Verdine, G., Harrison, S. C., Sauer, R., Mathews, F. S., Scheraga, H. A., Miller, K., Brunzelle, J., Anderson, W., Xiaolin, H., Hong, L., Tong, L., Gaudet, R., Sicheri, F., Patel, D., Lima, C., Wu, H. A. O., Schwartz, T., Taylor, A., Clardy, J. O. N., Hogle, J., Lovell, S., Sakmar, T., Almo, S., Tanner, J., Perozo, E., Kent, S., Dong, Z., Christianson, D., Yeates, T., Spiller, B., Keating, A., Eisenberg, D., Tahirov, T., Schulman, B., Cate, J., Walker, S., Garman, S. C., Rajashankar, K., Sukumar, N., Rongsheng, J., Roux, B., Aihara, H., Herr, A., Khan, A., Hart, P., Dunham, C., Deivanayagam, C. C. S., Modis, Y., Fitzpatrick, P. F., Fang, L., Koide, S., Joseph, H., Ploegh, H., Agris, P., Toor, N. S., Clardy, J. O. N., Nikolov, D., Shapiro, L., Wang, J., Eck, M., Rajashankar, K., Blobel, G., Bartel, D., Sanders, D., Darst, S., Santarsiero, B. D., Ellenberger, T., Pyle, A. M., Sondermann, H., Lippard, S. J., Ailong, K., Edward, Y., Aggarwal, A. K., Jeruzalmi, D., Shuman, S., Yong-Hwan, L., Heldwein, E., Murphy, F., Jogl, G., Nikolov, D., Johnson, R., Shapiro, L., Baker, B., Santarsiero, B. D., Hogle, J., Modis, Y., Wucherpfennig, K., Newcomer, M. E., Dauter, Z., Cheng, X., Walter, M., Quiocho, F., Schlessinger, J., Cerione, R. A., Capel, M., Xavier, L., Yaffe, M., Misono, K., Golden, B. L., Ogata, C., Wimberly, B., Pavletich, N., Steitz, T. A., Rapoport, T., Fait, J., Nielsen, C., Breslow, E., Von Dreele, R., Decamilli, P., Phillips, G. N., Stauffacher, C., Keenan, R., Kang, C., Kissinger, C., Cabral, J., Dealwis, C., Lawrence, C. M., Strobel, S., Tong, H., Petsko, G., Chen, J. U. E., Rongbao, L., Furie, B., Howard, A. J., Hong, Y., Reinisch, K., Hendrickson, W. A., Ling, H., Mathews, S., Capel, M. S., Kissinger, C. R., Berger, J., Samanta, U., Jianhua, F., Kirchhausen, T. O. M., Morais-Cabral, J., Aaron, J., Cerione, R. A., Abramson, J., Cantley, L. C., Fan, Q., D'Aquino Ruiz, J. A., Brunger, A. T., De Camilli, P., Geiger, J., Goldberg, J., Caffrey, M. D., Wagner, G., H Eric, X., Fromme, J. C., Lacy, D. B., Anjana, R., Hunt, J., Feigon, J., Loll, P., Jardetzky, T., Stenkamp, R., Blacklow, S., Zhou, M., Springer, T., MacKinnon, R., Song, T., Laronde, N., Xiong, Y., Gouaux, J. E., Decamilli, P., Bochkarev, A., Vivien, Y., van Den Berg, B., Yuxin, M., Kamtekar, S., Nimigean, C., Silverstein, R. O. Y., Muesar, T., Hur, S. U. N., Ha, Y. A., Braddock, D., Strobel, S., Hardy, J., Degrado, W., Luecke, H., Sthanam, N., Feng, G., Hazen, S., Baxter, J., Dealwis, C., Choe, J., Chuan, H., Mancia, F., Lemmon, M. A., Lewis, M., Goldberg, J., Chen, B., Asojo, O. A., Hogbom, M., Konigsberg, W., Bhyravbhatla, B., van Duyne, G., Anjana, R. & Sazinsky, M.

National Institutes of Health

6/15/013/31/13

Project: Research project

Exoribonucleases
RNA
Escherichia coli
Uridine
Enzymes

Research Output 1987 2018

  • 2422 Citations
  • 61 Article
2 Citations (Scopus)

Combined functions of two RRMs in Dead-end1 mimic helicase activity to promote nanos1 translation in the germline

Aguero, T., Jin, Z., Owens, D., Malhotra, A., Newman, K., Yang, J. & King, M. L. L., Jan 1 2018, (Accepted/In press) In : Molecular Reproduction and Development.

Research output: Contribution to journalArticle

Messenger RNA
Zebrafish
Xenopus
Adenosine Triphosphatases
Open Reading Frames
1 Citation (Scopus)

Evidence of disulfide bond scrambling during production of an antibody-drug conjugate

Liu-Shin, L. P. Y., Fung, A., Malhotra, A. & Ratnaswamy, G., Nov 17 2018, In : mAbs. 10, 8, p. 1190-1199 10 p.

Research output: Contribution to journalArticle

Disulfides
Antibody Formation
Immunoglobulin G
Antibodies
Pharmaceutical Preparations
6 Citations (Scopus)

Influence of disulfide bond isoforms on drug conjugation sites in cysteine-linked IgG2 antibody-drug conjugates

Liu-Shin, L., Fung, A., Malhotra, A. & Ratnaswamy, G., May 19 2018, In : mAbs. 10, 4, p. 583-595 13 p.

Research output: Contribution to journalArticle

Disulfides
Cysteine
Protein Isoforms
Immunoglobulin G
Antibodies
1 Citation (Scopus)

Rapid, automated characterization of disulfide bond scrambling and IgG2 isoform determination

Resemann, A., Liu-Shin, L., Tremintin, G., Malhotra, A., Fung, A., Wang, F., Ratnaswamy, G. & Suckau, D., Nov 17 2018, In : mAbs. 10, 8, p. 1200-1213 14 p.

Research output: Contribution to journalArticle

Disulfides
Protein Isoforms
Immunoglobulin G
Peptides
Workflow
3 Citations (Scopus)

Structural Basis for the Bidirectional Activity of Bacillus nanoRNase NrnA

Schmier, B. J., Nelersa, C. M. & Malhotra, A., Dec 1 2017, In : Scientific Reports. 7, 1, 11085.

Research output: Contribution to journalArticle

Bacillus
RNA
Nucleotides
Exonucleases
Deoxyribonucleases