Arba L Ager

Voluntary Associate Professor-Podack

  • 2213 Citations
1976 …2018
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Antimalarials Medicine & Life Sciences
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Plasmodium falciparum Medicine & Life Sciences
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Chloroquine Medicine & Life Sciences
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Research Output 1976 2018

  • 2213 Citations
  • 54 Article
  • 1 Chapter
  • 1 Review article
1 Citations

Characterization of the preclinical pharmacology of the new 2-aminomethylphenol, JPC-3210, for malaria treatment and prevention

Birrell, G. W., Heffernan, G. D., Schiehser, G. A., Anderson, J., Ager, A. L., Morales, P., MacKenzie, D., Van Breda, K., Chavchich, M., Jacobus, L. R., Shanks, G. D., Jacobus, D. P. & Edstein, M. D., Apr 1 2018, In : Antimicrobial Agents and Chemotherapy. 62, 4, e01335-17.

Research output: Contribution to journalArticle

Malaria
Pharmacology
Isoenzymes
Cytochrome P-450 Enzyme System
Biological Availability

The eIF2α kinase heme-regulated inhibitor protects the host from infection by regulating intracellular pathogen trafficking

Bahnan, W., Boucher, J. C., Gayle, P., Shrestha, N., Rosen, M., Aktas, B., Adkins, R. D., Ager, A. L., Khan, W. & Schesser, K., Mar 1 2018, In : Infection and Immunity. 86, 3, e00707-17.

Research output: Contribution to journalArticle

eIF-2 Kinase
Heme
Listeria monocytogenes
Infection
Listeriosis
5 Citations

Lead selection of a new aminomethylphenol, JPC-3210, for malaria treatment and prevention

Chavchich, M., Birrell, G. W., Ager, A. L., MacKenzie, D. O., Heffernan, G. D., Schiehser, G. A., Jacobus, L. R., Shanks, G. D., Jacobus, D. P. & Edstein, M. D., May 1 2016, In : Antimicrobial Agents and Chemotherapy. 60, 5, p. 3115-3118 4 p.

Research output: Contribution to journalArticle

Malaria
Antimalarials
Plasmodium falciparum
Structure-Activity Relationship
Phenol
7 Citations

JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium

Birrell, G. W., Chavchich, M., Ager, A. L., Shieh, H. M., Heffernan, G. D., Zhao, W., Krasucki, P. E., Saionz, K. W., Terpinski, J., Schiehser, G. A., Jacobus, L. R., Shanks, G. D., Jacobus, D. P. & Edstein, M. D., Jan 1 2015, In : Antimicrobial Agents and Chemotherapy. 59, 1, p. 170-177 8 p.

Research output: Contribution to journalArticle

Plasmodium
Antimalarials
Chloroquine
Plasmodium falciparum
Haplorhini

A Targeted and Adjuvanted Nanoparticle for Immunochemotherapy of Leishmania Infections

Daftarian, P. M., Ager, A. L. & Stone, G., Sep 1 2014, In : Current Tropical Medicine Reports. 1, 3, p. 148-153 6 p.

Research output: Contribution to journalReview article

Dendrimers
Leishmania
Nanoparticles
Phagocytes
Leishmaniasis