Anthony J Capobianco

Professor

  • 4309 Citations
1990 …2019
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Research Output 1990 2019

  • 4309 Citations
  • 79 Article
  • 1 Editorial
Article
6 Citations (Scopus)

Acetylation of mastermind-like 1 by p300 drives the recruitment of NACK to initiate Notch-dependent transcription

Jin, K., Zhou, W., Han, X., Wang, Z., Li, B., Jeffries, S., Tao, W., Robbins, D. J. & Capobianco, A. J., Aug 15 2017, In : Cancer Research. 77, 16, p. 4228-4237 10 p.

Research output: Contribution to journalArticle

RNA Polymerase II
Acetylation
Adenocarcinoma
Phosphotransferases
Amino Acids
2 Citations (Scopus)

A CK1a Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma

Rodriguez-Blanco, J., Li, B., Long, J., Shen, C., Yang, F., Orton, D., Collins, S., Kasahara, N., Ayad, N., McCrea, H. J., Roussel, M. F., Weiss, W. A., Capobianco, A. J. & Robbins, D. J., Feb 15 2019, In : Clinical Cancer Research. 25, 4, p. 1379-1388 10 p.

Research output: Contribution to journalArticle

Casein Kinases
Medulloblastoma
Hedgehogs
Brain
Pharmaceutical Preparations
13 Citations (Scopus)

A conditional mutant of vRel containing sequences from the human estrogen receptor

Capobianco, A. J. & Gilmore, T. D., Jan 1 1993, In : Virology. 193, 1, p. 160-170 11 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Chickens
Embryonic Structures
Fibroblasts
247 Citations (Scopus)

Activation of Notch1 signaling is required for β-catenin-mediated human primary melanoma progression

Balint, K., Xiao, M., Pinnix, C. C., Soma, A., Veres, I., Juhasz, I., Brown, E. J., Capobianco, A. J., Herlyn, M. & Liu, Z-J., Nov 1 2005, In : Journal of Clinical Investigation. 115, 11, p. 3166-3176 11 p.

Research output: Contribution to journalArticle

Catenins
Melanoma
Growth
Transcriptional Activation
Neoplasms
88 Citations (Scopus)

Active Notch1 confers a transformed phenotype to primary human melanocytes

Pinnix, C. C., Lee, J. T., Liu, Z-J., McDaid, R., Balint, K., Beverly, L. J., Brafford, P. A., Xiao, M., Himes, B., Zabierowski, S. E., Yashiro-Ohtani, Y., Nathanson, K. L., Bengston, A., Pollock, P. M., Weeraratna, A. T., Nickoloff, B. J., Pear, W. S., Capobianco, A. J. & Herlyn, M., Jul 1 2009, In : Cancer Research. 69, 13, p. 5312-5320 9 p.

Research output: Contribution to journalArticle

Melanocytes
Melanoma
Phenotype
Oncogenes
Mitogen-Activated Protein Kinases
91 Citations (Scopus)

A Protein Kinase-A Recognition Sequence Is Structurally Linked to Transformation by p59v-rel and Cytoplasmic Retention of p68c-rel

Mosialos, G., Hamer, P., Capobianco, A. J., Laursen, R. A. & Gilmore, T. D., Dec 1 1991, In : Molecular and Cellular Biology. 11, 12, p. 5867-5877 11 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Protein Kinases
Chickens
Embryonic Structures
Fibroblasts
5 Citations (Scopus)

Arsenic attenuates gli signaling, increasing or decreasing its transcriptional program in a context-dependent manner

Li, B., Giambelli, C., Tang, B., Winterbottom, E., Long, J., Jin, K., Wang, Z., Fei, D. L., Nguyen, D. M., Athar, M., Wang, B., Pochi, S., Wang, L., Rai, P., Ardalan, B., Capobianco, A. J. & Robbins, D. J., Feb 1 2016, In : Molecular Pharmacology. 89, 2, p. 226-232 7 p.

Research output: Contribution to journalArticle

Arsenic
Hedgehogs
Colorectal Neoplasms
Hedgehog Proteins
Metalloids
15 Citations (Scopus)

Assembly of a notch transcriptional activation complex requires multimerization

Vasquez-Del Carpio, R., Kaplan, F. M., Weaver, K. L., VanWye, J. D., Alves-Guerra, M. C., Robbins, D. J. & Capobianco, A. J., Apr 1 2011, In : Molecular and Cellular Biology. 31, 7, p. 1396-1408 13 p.

Research output: Contribution to journalArticle

Transcriptional Activation
Notch Receptors
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
DNA-Binding Proteins
Cell Communication
30 Citations (Scopus)

BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development

Bai, F., Chan, H. L., Scott, A., Smith, M. D., Fan, C., Herschkowitz, J. I., Perou, C. M., Livingstone, A., Robbins, D. J., Capobianco, A. J. & Pei, X-H., Nov 1 2014, In : Cancer Research. 74, 21, p. 6161-6172 12 p.

Research output: Contribution to journalArticle

Cell Dedifferentiation
Epithelial-Mesenchymal Transition
Mesenchymal Stromal Cells
Breast Neoplasms
Stem Cells
9 Citations (Scopus)

Characterization of a chicken cDNA encoding the retinoblastoma gene product

Feinstein, R., Bolton, W. K., Quinones, J. N., Mosialos, G., Sif, S., Huff, J. L., Capobianco, A. J. & Gilmore, T. D., May 17 1994, In : BBA - Gene Structure and Expression. 1218, 1, p. 82-86 5 p.

Research output: Contribution to journalArticle

Retinoblastoma Genes
Chickens
Complementary DNA
Genes
Proteins
125 Citations (Scopus)
T-Cell Leukemia
Molecular Weight
Cell Line
Neoplastic Cell Transformation
Notch Receptors
73 Citations (Scopus)

Cloning and expression of a chicken c-rel cDNA: Unlike p59v-rel, p68c-rel is a cytoplasmic protein in chicken embryo fibroblasts

Capobianco, A. J., Simmons, D. L. & Gilmore, T. D., Mar 1 1990, In : Oncogene. 5, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

Organism Cloning
Chickens
Embryonic Structures
Complementary DNA
Fibroblasts
5 Citations (Scopus)

Differential abundance of CK1a provides selectivity for pharmacological CK1a activators to target WNT-dependent tumors

Li, B., Orton, D., Neitzel, L. R., Astudillo, L., Shen, C., Long, J., Chen, X., Kirkbride, K. C., Doundoulakis, T., Guerra, M. L., Zaias, J., Fei, D. L., Rodriguez-Blanco, J., Thorne, C., Wang, Z., Jin, K., Nguyen, D., Sands, L., Marchetti, F., Abreu, M. T. & 4 others, Cobb, M. H., Capobianco, A. J., Lee, E. & Robbin, D. J., Jun 27 2017, In : Science Signaling. 10, 485, aak9916.

Research output: Contribution to journalArticle

Casein Kinases
Tumors
Pharmacology
Colorectal Neoplasms
Neoplasms

Editor's Choice: Epigenetic Pathways and Glioblastoma Treatment: Insights from Signaling Cascades

Allen, B. K., Stathias, V., Maloof, M. E., Vidovic, D., Winterbottom, E. F., Capobianco, A. J., Clarke, J., Schuerer, S. C., Robbins, D. J. & Ayad, N., Mar 1 2015, In : Journal of Cellular Biochemistry. 116, 3, p. iii

Research output: Contribution to journalArticle

131 Citations (Scopus)

Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

Carlson, T. R., Yan, Y., Wu, X., Lam, M. T., Tang, G. L., Beverly, L. J., Messina, L. M., Capobianco, A. J., Werb, Z. & Wang, R., Jul 12 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 28, p. 9884-9889 6 p.

Research output: Contribution to journalArticle

Arteriovenous Malformations
Blood Vessels
Endothelium
Liver
Tetracycline
153 Citations (Scopus)

Enhanced tumor formation in mice heterozygous for Blm mutation

Goss, K. H., Risinger, M. A., Kordich, J. J., Sanz, M. H., Straughen, J. E., Slovek, L. E., Capobianco, A. J., German, J., Boivin, G. P. & Groden, J., Sep 20 2002, In : Science. 297, 5589, p. 2051-2053 3 p.

Research output: Contribution to journalArticle

Mutation
Neoplasms
RecQ Helicases
Bloom Syndrome
Haploinsufficiency
6 Citations (Scopus)

Epigenetic Pathways and Glioblastoma Treatment: Insights from Signaling Cascades

Allen, B. K., Stathias, V., Maloof, M. E., Vidovic, D., Winterbottom, E. F., Capobianco, A. J., Clarke, J., Schuerer, S. C., Robbins, D. J. & Ayad, N., Mar 1 2015, In : Journal of Cellular Biochemistry. 116, 3, p. 351-363 13 p.

Research output: Contribution to journalArticle

DNA sequences
Cell proliferation
Drug Combinations
Glioblastoma
Epigenomics
16 Citations (Scopus)

Epimorphic regeneration in mice is p53-independent

Arthur, L. M., Demarest, R. M., Clark, L., Gourevitch, D., Bedelbaeva, K., Anderson, R., Snyder, A., Capobianco, A. J., Lieberman, P., Feigenbaum, L. & Heber-Katz, E., Sep 15 2010, In : Cell Cycle. 9, 18, p. 3667-3673 7 p.

Research output: Contribution to journalArticle

Regeneration
Ear
DNA Damage
Cell Cycle
Ear Auricle
5 Citations (Scopus)

Exposure of Barrett’s and esophageal adenocarcinoma cells to bile acids activates EGFR–STAT3 signaling axis via induction of APE1

Bhat, A. A., Lu, H., Soutto, M., Capobianco, A. J., Rai, P., Zaika, A. & El-Rifai, W., Jul 10 2018, (Accepted/In press) In : Oncogene. p. 1-14 14 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Oxidation-Reduction
Adenocarcinoma
Barrett Esophagus
Phosphorylation
3 Citations (Scopus)

Expression of JAGGED1 in T-lymphocytes results in thymic involution by inducing apoptosis of thymic stromal epithelial cells

Beverly, L. J., Ascano, J. M. & Capobianco, A. J., Sep 1 2006, In : Genes and Immunity. 7, 6, p. 476-486 11 p.

Research output: Contribution to journalArticle

Stromal Cells
Epithelial Cells
Apoptosis
T-Lymphocytes
Thymus Gland

Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma

Lohse, I., Al-Ali, H., Volmar, C. H., Alvarez Trotta, A. D., Brothers, S. P., Capobianco, A. J. & Wahlestedt, C. R., Sep 1 2018, In : PLoS One. 13, 9, e0203173.

Research output: Contribution to journalArticle

Drug Repositioning
esophageal neoplasms
adenocarcinoma
Adenocarcinoma
Cells
3 Citations (Scopus)

Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis

Liu, S., Chan, H. L., Bai, F., Ma, J., Scott, A., Robbins, D. J., Capobianco, A. J., Zhu, P. & Pei, X-H., 2016, In : Oncotarget. 7, 39, p. 64007-64020 14 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Cell Proliferation
Haploidy
B-Cell Lymphoma
T-Lymphocytes
11 Citations (Scopus)

GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth

Winterbottom, E. F., Fei, D. L., Koestler, D. C., Giambelli, C., Wika, E., Capobianco, A. J., Lee, E., Marsit, C. J., Karagas, M. R. & Robbins, D. J., Jun 1 2015, In : EBioMedicine. 2, 6, p. 536-543 8 p.

Research output: Contribution to journalArticle

Environmental Exposure
Arsenic
Fetal Development
Health
Placenta
32 Citations (Scopus)

Hedgehog-producing cancer cells respond to and require autocrine hedgehog activity

Singh, S., Wang, Z., Fei, D. L., Black, K. E., Goetz, J. A., Tokhunts, R., Giambelli, C., Rodriguez-Blanco, J., Long, J., Lee, E., Briegel, K., Bejarano, P. A., Dmitrovsky, E., Capobianco, A. J. & Robbins, D. J., Jul 1 2011, In : Cancer Research. 71, 13, p. 4454-4463 10 p.

Research output: Contribution to journalArticle

Neoplasms
Autocrine Communication
Stromal Cells
Growth
Antineoplastic Agents
28 Citations (Scopus)

Hedgehog signaling regulates bladder cancer growth and tumorigenicity

Fei, D. L., Sanchez-Mejias, A., Wang, Z., Flaveny, C., Long, J., Singh, S., Rodriguez-Blanco, J., Tokhunts, R., Giambelli, C., Briegel, K., Schulz, W. A., Gandolfi, A. J., Karagas, M., Zimmers, T. A., Jorda, M., Bejarano, P., Capobianco, A. J. & Robbins, D. J., Sep 1 2012, In : Cancer Research. 72, 17, p. 4449-4458 10 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Growth
Carcinoma
Cell Line
Tumor Suppressor Genes
28 Citations (Scopus)

Hierarchical phosphorylation within the ankyrin repeat domain defines a phosphoregulatory loop that regulates notch transcriptional activity

Ranganathan, P., Vasquez-Del Carpio, R., Kaplan, F. M., Wang, H., Gupta, A., VanWye, J. D. & Capobianco, A. J., Aug 19 2011, In : Journal of Biological Chemistry. 286, 33, p. 28844-28857 14 p.

Research output: Contribution to journalArticle

Ankyrin Repeat
Phosphorylation
Threonine
Casein Kinase II
Serine
18 Citations (Scopus)

Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties

Long, J., Tokhunts, R., Old, W. M., Houel, S., Rodgriguez-Blanco, J., Singh, S., Schilling, N., Capobianco, A. J., Ahn, N. G. & Robbins, D. J., Mar 3 2015, In : Cell Reports. 10, 8, p. 1280-1287 8 p.

Research output: Contribution to journalArticle

Hedgehog Proteins
Fatty Acids
Lipids
Palmitates
Proteins
7 Citations (Scopus)

Identification of a Paralog-Specific Notch1 Intracellular Domain Degron

Broadus, M. R., Chen, T. W., Neitzel, L. R., Ng, V. H., Jodoin, J. N., Lee, L. A., Salic, A., Robbins, D. J., Capobianco, A. J., Patton, J. G., Huppert, S. S. & Lee, E., May 31 2016, In : Cell Reports. 15, 9, p. 1920-1929 10 p.

Research output: Contribution to journalArticle

Zebrafish
Degradation
Mutation
Ovum
Cultured Cells
309 Citations (Scopus)
Cyclin D1
Cell Cycle
Proteins
bcl-1 Genes
Hormones
88 Citations (Scopus)

Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1

Liu, Z-J., Xiao, M., Balint, K., Soma, A., Pinnix, C. C., Capobianco, A. J., Velazquez, O. C. & Herlyn, M., May 1 2006, In : FASEB Journal. 20, 7

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Endothelial cells
phosphatidylinositol 3-kinase
Cell proliferation
Mitogen-Activated Protein Kinases
5 Citations (Scopus)

Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma

Rodriguez-Blanco, J., Pednekar, L., Penas, C., Li, B., Martin, V., Long, J., Lee, E., Weiss, W. A., Rodriguez, C., Nadji, M., Nguyen, D., Ayad, N., Rai, P., Capobianco, A. J. & Robbins, D. J., Nov 9 2017, In : Oncogene. 36, 45, p. 6306-6314 9 p.

Research output: Contribution to journalArticle

HhAntag691
Medulloblastoma
Neoplasms
Basal Cell Carcinoma
Recurrence
85 Citations (Scopus)

It's T-ALL about Notch

Demarest, R. M., Ratti, F. & Capobianco, A. J., Sep 1 2008, In : Oncogene. 27, 38, p. 5082-5091 10 p.

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Apoptosis
Mutation
p53 Genes
Neoplasms
65 Citations (Scopus)

Mastermind-like 1 is a specific coactivator of β-catenin transcription activation and is essential for colon carcinoma cell survival

Alves-Guerra, M. C., Ronchini, C. & Capobianco, A. J., Sep 15 2007, In : Cancer Research. 67, 18, p. 8690-8698 9 p.

Research output: Contribution to journalArticle

Catenins
Transcriptional Activation
Cell Survival
Colon
Carcinoma
97 Citations (Scopus)

Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein

Zhang, X. Y., DeSalle, L. M., Patel, J. H., Capobianco, A. J., Yu, D., Thomas-Tikhonenko, A. & McMahon, S. B., Sep 27 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 39, p. 13968-13973 6 p.

Research output: Contribution to journalArticle

Oncogene Proteins
Neoplasm Metastasis
Nucleosomes
Proteins
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
13 Citations (Scopus)

NACK is an integral component of the notch transcriptional activation complex and is critical for development and tumorigenesis

Weaver, K. L., Alves-Guerra, M. C., Jin, K., Wang, Z., Han, X., Ranganathan, P., Zhu, X., DaSilva, T., Liu, W., Ratti, F., Demarest, R. M., Tzimas, C., Rice, M., Vasquez-Del Carpio, R., Dahmane, N., Robbins, D. J. & Capobianco, A. J., Sep 1 2014, In : Cancer Research. 74, 17, p. 4741-4751 11 p.

Research output: Contribution to journalArticle

Transcriptional Activation
Carcinogenesis
Phosphotransferases
Notch Receptors
Genes
98 Citations (Scopus)

Neoplastic transformation by Notch requires nuclear localization

Jeffries, S. & Capobianco, A. J., Jun 1 2000, In : Molecular and Cellular Biology. 20, 11, p. 3928-3941 14 p.

Research output: Contribution to journalArticle

Proto-Oncogenes
Kidney
Cell Membrane
Notch Receptors
Oncogene Proteins
208 Citations (Scopus)

Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2

Capobianco, A. J., Zagouras, P., Blaumueller, C. M., Artavanis-Tsakonas, S. & Bishop, J. M., Nov 1 1997, In : Molecular and Cellular Biology. 17, 11, p. 6265-6273 9 p.

Research output: Contribution to journalArticle

Alleles
Proteins
Notch Receptors
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Genetic Translocation
38 Citations (Scopus)

Notch(ic)-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation

Ronchini, C. & Capobianco, A. J., Aug 10 2000, In : Oncogene. 19, 34, p. 3914-3924 11 p.

Research output: Contribution to journalArticle

Phosphorylation
Hormones
Notch Receptors
Cell Nucleus
Oncogenes
191 Citations (Scopus)

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc

Sharma, V. M., Calvo, J. A., Draheim, K. M., Cunningham, L. A., Hermance, N., Beverly, L., Krishnamoorthy, V., Bhasin, M., Capobianco, A. J. & Kelliher, M. A., Nov 1 2006, In : Molecular and Cellular Biology. 26, 21, p. 8022-8031 10 p.

Research output: Contribution to journalArticle

T-Cell Leukemia
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Amyloid Precursor Protein Secretases
Notch1 Receptor
T-Lymphocytes
35 Citations (Scopus)

Notch1 co-opts lymphoid enhancer factor 1 for survival of murine T-cell lymphomas

Spaulding, C., Reschly, E. J., Zagort, D. E., Yashiro-Ohtani, Y., Beverly, L. J., Capobianco, A. J., Pear, W. S. & Kee, B. L., Oct 1 2007, In : Blood. 110, 7, p. 2650-2658 9 p.

Research output: Contribution to journalArticle

TCF Transcription Factors
T-cells
T-Cell Lymphoma
Survival
Cell death
101 Citations (Scopus)

Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma

Hanlon, L., Avila, J. L., Demarest, R. M., Troutman, S., Allen, M., Ratti, F., Rustgi, A. K., Stanger, B. Z., Radtke, F., Adsay, V., Long, F., Capobianco, A. J. & Kissil, J. L., Jun 1 2010, In : Cancer Research. 70, 11, p. 4280-4286 7 p.

Research output: Contribution to journalArticle

Oncogenes
Adenocarcinoma
Notch Receptors
Tumor Suppressor Genes
Pancreatic Neoplasms
63 Citations (Scopus)

Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53

Licciulli, S., Avila, J. L., Hanlon, L., Troutman, S., Cesaroni, M., Kota, S., Keith, B., Simon, M. C., Puré, E., Radtke, F., Capobianco, A. J. & Kissil, J. L., Oct 1 2013, In : Cancer Research. 73, 19, p. 5974-5984 11 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Survival
Neoplasms
Oncogenes
Carcinogenesis
8 Citations (Scopus)

Notch1 pathway activity determines the regulatory role of cancer-associated fibroblasts in melanoma growth and invasion

Shao, H., Kong, R., Ferrari, M. L., Radtke, F., Capobianco, A. J. & Liu, Z-J., Nov 1 2015, In : PLoS One. 10, 11, e0142815.

Research output: Contribution to journalArticle

Fibroblasts
melanoma
fibroblasts
Melanoma
neoplasms
24 Citations (Scopus)

Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL

Pelullo, M., Quaranta, R., Talora, C., Checquolo, S., Cialfi, S., Felli, M. P. I., te Kronnie, G., Borga, C., Besharat, Z. M. E., Palermo, R., Di Marcotullio, L., Capobianco, A. J., Gulino, A., Screpanti, I. & Bellavia, D., Dec 1 2014, In : Neoplasia (United States). 16, 12, p. 1007-1017 11 p.

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Ligands
T-Cell Lymphoma
Transcriptional Activation
Lymphoma
30 Citations (Scopus)

Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia

Demarest, R. M., Dahmane, N. & Capobianco, A. J., Mar 10 2011, In : Blood. 117, 10, p. 2901-2909 9 p.

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
T-cells
Tumors
Neoplasms
Genes

Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia (Blood (2011) 117, 10, (2901-2909))

Demarest, R. M., Dahmane, N. & Capobianco, A. J., Jun 16 2011, In : Blood. 117, 24

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
1 Citation (Scopus)

Notch represses transcription by PRC2 recruitment to the ternary complex

Han, X., Ranganathan, P., Tzimas, C., Weaver, K. L., Jin, K., Astudillo, L., Zhou, W., Zhu, X., Li, B., Robbins, D. J. & Capobianco, A. J., Sep 1 2017, In : Molecular Cancer Research. 15, 9, p. 1173-1183 11 p.

Research output: Contribution to journalArticle

Epigenomics
Carcinogenesis
Gene Expression
Enzymes
Therapeutics
41 Citations (Scopus)

Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma

Wang, Z., Da Silva, T. G., Jin, K., Han, X., Ranganathan, P., Zhu, X., Sanchez-Mejias, A., Bai, F., Li, B., Fei, D. L., Weaver, K., Vasquez-Del Carpio, R., Moscowitz, A. E., Koshenkov, V. P., Sanchez, L., Sparling, L., Pei, X-H., Franceschi, D., Ribeiro, A., Robbins, D. J. & 2 others, Livingstone, A. & Capobianco, A. J., Nov 1 2014, In : Cancer Research. 74, 21, p. 6364-6374 11 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Amyloid Precursor Protein Secretases
Drug Therapy
Neoplastic Stem Cells
Heterografts
106 Citations (Scopus)

Notch signaling mediates G 1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

Joshi, I., Minter, L. M., Telfer, J., Demarest, R. M., Capobianco, A. J., Aster, J. C., Sicinski, P., Fauq, A., Golde, T. E. & Osborne, B. A., Feb 19 2009, In : Blood. 113, 8, p. 1689-1698 10 p.

Research output: Contribution to journalArticle

Cyclin D3
T-cells
Cell Cycle
Phosphotransferases
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma