Anthony J Capobianco

Professor

  • 4344 Citations
1990 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 4344 Citations
  • 78 Article
  • 1 Editorial

Notch signaling mediates G 1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

Joshi, I., Minter, L. M., Telfer, J., Demarest, R. M., Capobianco, A. J., Aster, J. C., Sicinski, P., Fauq, A., Golde, T. E. & Osborne, B. A., Feb 19 2009, In : Blood. 113, 8, p. 1689-1698 10 p.

Research output: Contribution to journalArticle

110 Scopus citations

Notch signalling in solid tumours: A little bit of everything but not all the time

Ranganathan, P., Weaver, K. L. & Capobianco, A. J., May 1 2011, In : Nature Reviews Cancer. 11, 5, p. 338-351 14 p.

Research output: Contribution to journalArticle

482 Scopus citations

p105, the NF-κB p50 precursor protein, is one of the cellular proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells

Capobianco, A. J., Chang, D., Mosialos, G. & Gilmore, T. D., Jun 1 1992, In : Journal of Virology. 66, 6, p. 3758-3767 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

p16INK4a suppresses BRCA1-deficient mammary tumorigenesis

Scott, A., Bai, F., Chan, H. L., Liu, S., Ma, J., Slingerland, J. M., Robbins, D. J., Capobianco, A. J. & Pei, X-H., 2016, In : Oncotarget. 7, 51, p. 84496-84507 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

p16 loss rescues functional decline of Brca1-deficient mammary stem cells

Scott, A., Bai, F., Chan, H. L., Liu, S., Slingerland, J. M., Robbins, D. J., Capobianco, A. J. & Pei, X-H., Mar 10 2017, (Accepted/In press) In : Cell Cycle. p. 1-6 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in NotchIC-induced T cell leukemogenesis

Beverly, L. J. & Capobianco, A. J., Jun 1 2003, In : Cancer Cell. 3, 6, p. 551-564 14 p.

Research output: Contribution to journalArticle

119 Scopus citations

Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner 06 Biological Sciences 0604 Genetics 11 Medical and Health Sciences 1114 Paediatrics and Reproductive Medicine

Winterbottom, E. F., Moroishi, Y., Halchenko, Y., Armstrong, D. A., Beach, P. J., Nguyen, Q. P., Capobianco, A. J., Ayad, N. G., Marsit, C. J., Li, Z., Karagas, M. R. & Robbins, D. J., Feb 28 2019, In : Environmental Health: A Global Access Science Source. 18, 1, 18.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Proto-oncogenes and plasticity in cell signaling

Bishop, J. M., Capobianco, A. J., Doyle, H. J., Finney, R. E., McMahon, M., Robbins, S. M., Samuels, M. L. & Vetter, M., Dec 1 1994, In : Cold Spring Harbor Symposia on Quantitative Biology. 59, p. 165-171 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pyrvinium attenuates hedgehog signaling downstream of smoothened

Li, B., Fei, D. L., Flaveny, C. A., Dahmane, N., Baubet, V., Wang, Z., Bai, F., Pei, X-H., Rodriguez-Blanco, J., Hang, B., Orton, D., Han, L., Wang, B., Capobianco, A. J., Lee, E. & Robbins, D. J., Sep 1 2014, In : Cancer Research. 74, 17, p. 4811-4821 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Repression of activator protein-1-mediated transcriptional activation by the notch-1 intracellular domain

Chu, J., Jeffries, S., Norton, J. E., Capobianco, A. J. & Bresnick, E. H., Mar 1 2002, In : Journal of Biological Chemistry. 277, 9, p. 7587-7597 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

Repression of the chicken c-rel promoter by vRel in chicken embryo fibroblasts is not mediated through a consensus NF-κB binding site

Capobianco, A. J. & Gilmore, T. D., Dec 1 1991, In : Oncogene. 6, 12, p. 2203-2210 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis

Li, B., Flaveny, C. A., Giambelli, C., Liang Fei, D., Han, L., Hang, B. I., Bai, F., Pei, X-H., Nose, V., Burlingame, O., Capobianco, A. J., Orton, D., Lee, E. & Robbins, D. J., Jul 8 2014, In : PLoS One. 9, 7, e101969.

Research output: Contribution to journalArticle

23 Scopus citations

Requirement for Rac1 in a K-ras-induced lung cancer in the mouse

Kissil, J. L., Walmsley, M. J., Hanlon, L., Haigis, K. M., Kim, C. F. B., Sweet-Cordero, A., Eckman, M. S., Tuveson, D. A., Capobianco, A. J., Tybulewicz, V. L. J. & Jacks, T., Sep 1 2007, In : Cancer Research. 67, 17, p. 8089-8094 6 p.

Research output: Contribution to journalArticle

126 Scopus citations

Sp100 as a potent tumor suppressor: Accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program

Negorev, D. G., Vladimirova, O. V., Kossenkov V, A., Nikonova V, E., Demarest, R. M., Capobianco, A. J., Showe, M. K., Rauscher, F. J., Showe, L. C. & Maul, G. G., Dec 1 2010, In : Cancer Research. 70, 23, p. 9991-10001 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Suppression of erythroid but not megakaryocytic differentiation of human K562 Erythroleukemic cells by Notch-1

Lam, L. T., Ronchini, C., Norton, J., Capobianco, A. J. & Bresnick, E. H., Jun 30 2000, In : Journal of Biological Chemistry. 275, 26, p. 19676-19684 9 p.

Research output: Contribution to journalArticle

78 Scopus citations

Suppression of p53 by Notch in lymphomagenesis: Implications for initiation and regression

Beverly, L. J., Felsher, D. W. & Capobianco, A. J., Aug 15 2005, In : Cancer Research. 65, 16, p. 7159-7168 10 p.

Research output: Contribution to journalArticle

124 Scopus citations

Targeting promiscuous signaling pathways in cancer: Another Notch in the bedpost

Beverly, L. J. & Capobianco, A. J., Dec 1 2004, In : Trends in Molecular Medicine. 10, 12, p. 591-598 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression

Winterbottom, E. F., Koestler, D. C., Fei, D. L., Wika, E., Capobianco, A. J., Marsit, C. J., Karagas, M. R. & Robbins, D. J., Jun 14 2017, In : Environmental Health: A Global Access Science Source. 16, 1, 59.

Research output: Contribution to journalArticle

10 Scopus citations

The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers

Long, J., Li, B., Rodriguez-Blanco, J., Pastori, C., Volmar, C. H., Wahlestedt, C. R., Capobianco, A. J., Bai, F., Pei, X-H., Ayad, N. & Robbins, D. J., Dec 19 2014, In : Journal of Biological Chemistry. 289, 51, p. 35494-35502 9 p., A32.

Research output: Contribution to journalArticle

56 Scopus citations

The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (kcat/ Km) of CK1α

Shen, C., Li, B., Astudillo, L., Deutscher, M. P., Cobb, M. H., Capobianco, A. J., Lee, E. & Robbins, D. J., Dec 24 2019, In : Biochemistry. 58, 51, p. 5102-5106 5 p.

Research output: Contribution to journalArticle

The C-terminal PDZ-ligand of JAGGED1 is essential for cellular transformation

Ascano, J. M., Beverly, L. J. & Capobianco, A. J., Mar 7 2003, In : Journal of Biological Chemistry. 278, 10, p. 8771-8779 9 p.

Research output: Contribution to journalArticle

99 Scopus citations

The Hedgehog processing pathway is required for NSCLC growth and survival

Rodriguez-Blanco, J., Schilling, N. S., Tokhunts, R., Giambelli, C., Long, J., Liang Fei, D., Singh, S., Black, K. E., Wang, Z., Galimberti, F., Bejarano, P. A., Elliot, S., Glassberg Csete, M. K., Nguyen, D., Lockwood, W. W., Lam, W. L., Dmitrovsky, E., Capobianco, A. J. & Robbins, D. J., May 2 2013, In : Oncogene. 32, 18, p. 2335-2345 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

The notch signaling pathway in esophageal adenocarcinoma

Wang, Z., Chen, J. & Capobianco, A. J., 2015, In : Cellular and Molecular Biology. 61, 6, p. 24-32 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

Rustighi, A., Tiberi, L., Soldano, A., Napoli, M., Nuciforo, P., Rosato, A., Kaplan, F., Capobianco, A. J., Pece, S., Di Fiore, P. P. & Del Sal, G., Jan 19 2009, In : Nature Cell Biology. 11, 2, p. 133-142 10 p.

Research output: Contribution to journalArticle

116 Scopus citations

The small molecule IMR-1 inhibits the notch transcriptional activation complex to suppress tumorigenesis

Astudillo, L., Da Silva, T. G., Wang, Z., Han, X., Jin, K., VanWye, J., Zhu, X., Weaver, K., Oashi, T., Lopes, P. E. M., Orton, D., Neitzel, L. R., Lee, E., Landgraf, R., Robbins, D. J., MacKerell, A. D. & Capobianco, A. J., Jun 15 2016, In : Cancer Research. 76, 12, p. 3593-3603 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

The v-Rel oncoprotein increases expression from Sp1 site-containing promoters in chicken embryo fibroblasts

Sif, S., Capobianco, A. J. & Gilmore, T. D., Sep 1 1993, In : Oncogene. 8, 9

Research output: Contribution to journalArticle

38 Scopus citations

Transcriptome-wide analysis of changes in the fetal placenta associated with prenatal arsenic exposure in the New Hampshire Birth Cohort Study

Winterbottom, E. F., Ban, Y., Sun, X., Capobianco, A. J., Marsit, C. J., Chen, X., Wang, L., Karagas, M. R. & Robbins, D. J., Nov 21 2019, In : Environmental Health: A Global Access Science Source. 18, 1, 100.

Research output: Contribution to journalArticle

Open Access

Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

Azzam, D. J., Zhao, D., Sun, J., Minn, A. J., Ranganathan, P., Drews-Elger, K., Han, X., Picon-Ruiz, M., Gilbert, C. A., Wander, S. A., Capobianco, A. J., El-Ashry, D. & Slingerland, J. M., Oct 1 2013, In : EMBO Molecular Medicine. 5, 10, p. 1502-1522 21 p.

Research output: Contribution to journalArticle

42 Scopus citations

Whole Exome Sequencing of Lacrimal Gland Adenoid Cystic Carcinoma

Sant, D. W., Tao, W., Field, M. G., Pelaez, D., Jin, K., Capobianco, A. J., Dubovy, S., Tse, D. & Wang, G., May 1 2017, In : Investigative ophthalmology & visual science. 58, 6, p. BIO240-BIO246

Research output: Contribution to journalArticle

6 Scopus citations