Molecular and Cellular Pharmacology

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Review article
2019
1 Scopus citations

Neuronal nitric oxide synthase (nNOS) splice variant function: Insights into nitric oxide signaling from skeletal muscle

Balke, J. E., Zhang, L. & Percival, J. M., Jan 1 2019, In : Nitric Oxide - Biology and Chemistry. 82, p. 35-47 13 p.

Research output: Contribution to journalReview article

4 Scopus citations
2018

Drug repositioning in glioblastoma: A pathway perspective

Tan, S. K., Jermakowicz, A., Mookhtiar, A. K., Nemeroff, C., Schuerer, S. C. & Ayad, N., Mar 16 2018, In : Frontiers in Pharmacology. 9, MAR, 218.

Research output: Contribution to journalReview article

15 Scopus citations
2 Scopus citations

Secretogranin III: a diabetic retinopathy-selective angiogenic factor

Li, W., Webster, K. A., LeBlanc, M. E. & Tian, H., Feb 1 2018, In : Cellular and Molecular Life Sciences. 75, 4, p. 635-647 13 p.

Research output: Contribution to journalReview article

4 Scopus citations

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., Kuleshov, M. V., Ma'ayan, A., Stathias, V., Terryn, R., Cooper, D., Forlin, M., Koleti, A., Vidovic, D., Chung, C., Schuerer, S. C. & 87 others, Vasiliauskas, J., Pilarczyk, M., Shamsaei, B., Fazel, M., Ren, Y., Niu, W., Clark, N. A., White, S., Mahi, N., Zhang, L., Kouril, M., Reichard, J. F., Sivaganesan, S., Medvedovic, M., Meller, J., Koch, R. J., Birtwistle, M. R., Iyengar, R., Sobie, E. A., Azeloglu, E. U., Kaye, J., Osterloh, J., Haston, K., Kalra, J., Finkbiener, S., Li, J., Milani, P., Adam, M., Escalante-Chong, R., Sachs, K., Lenail, A., Ramamoorthy, D., Fraenkel, E., Daigle, G., Hussain, U., Coye, A., Rothstein, J., Sareen, D., Ornelas, L., Banuelos, M., Mandefro, B., Ho, R., Svendsen, C. N., Lim, R. G., Stocksdale, J., Casale, M. S., Thompson, T. G., Wu, J., Thompson, L. M., Dardov, V., Venkatraman, V., Matlock, A., Van Eyk, J. E., Jaffe, J. D., Papanastasiou, M., Subramanian, A., Golub, T. R., Erickson, S. D., Fallahi-Sichani, M., Hafner, M., Gray, N. S., Lin, J. R., Mills, C. E., Muhlich, J. L., Niepel, M., Shamu, C. E., Williams, E. H., Wrobel, D., Sorger, P. K., Heiser, L. M., Gray, J. W., Korkola, J. E., Mills, G. B., LaBarge, M., Feiler, H. S., Dane, M. A., Bucher, E., Nederlof, M., Sudar, D., Gross, S., Kilburn, D. F., Smith, R., Devlin, K., Margolis, R., Derr, L., Lee, A. & Pillai, A., Jan 24 2018, In : Cell Systems. 6, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

71 Scopus citations
9 Scopus citations

Unexplored therapeutic opportunities in the human genome

Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., Von Mering, C., Muthas, D., Nguyen, D. T., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schuerer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidović, D., Waller, A., Westergaard, D., Yang, J. J. & Zahoránszky-Köhalmi, G., Apr 27 2018, In : Nature Reviews Drug Discovery. 17, 5, p. 317-332 16 p.

Research output: Contribution to journalReview article

48 Scopus citations
2017

Developing a data sharing community for spinal cord injury research

Callahan, A., Anderson, K. D., Beattie, M. S., Bixby, J., Ferguson, A. R., Fouad, K., Jakeman, L. B., Nielson, J. L., Popovich, P. G., Schwab, J. M. & Lemmon, V., Sep 1 2017, In : Experimental Neurology. 295, p. 135-143 9 p.

Research output: Contribution to journalReview article

16 Scopus citations

NMNAT: It's an NAD+ synthase… It's a chaperone… It's a neuroprotector

Brazill, J. M., Li, C., Zhu, Y. & Zhai, R. G., Jun 1 2017, In : Current Opinion in Genetics and Development. 44, p. 156-162 7 p.

Research output: Contribution to journalReview article

16 Scopus citations

Pseudophosphorylation of cardiac myosin regulatory light chain: a promising new tool for treatment of cardiomyopathy

Yadav, S. & Szczesna-Cordary, D., Feb 1 2017, In : Biophysical Reviews. 9, 1, p. 57-64 8 p.

Research output: Contribution to journalReview article

4 Scopus citations
2016
7 Scopus citations

Myosin light chain phosphorylation, novel targets to repair a broken heart?

Szczesna-Cordary, D. & De Tombe, P. P., 2016, In : Cardiovascular Research. 111, 1, p. 5-7 3 p.

Research output: Contribution to journalReview article

5 Scopus citations
2015

The role of EF-hand Ca2+/Mg2+-binding tescalcin protein in cell proliferation and differentiation

Kolobynina, K. G., Solovyeva, V. V., Slepak, V. Z. & Rizvanov, A. A., 2015, In : Genes and Cells. 10, 1, p. 28-34 7 p.

Research output: Contribution to journalReview article

1 Scopus citations
2014

An overview of the challenges in designing, integrating, and delivering BARD: A public chemical-biology resource and query portal for multiple organizations, locations, and disciplines

De Souza, A., Bittker, J. A., Lahr, D. L., Brudz, S., Chatwin, S., Oprea, T. I., Waller, A., Yang, J. J., Southall, N., Guha, R., Schürer, S. C., Vempati, U. D., Southern, M. R., Dawson, E. S., Clemons, P. A. & Chung, T. D. Y., Jun 2014, In : Journal of Biomolecular Screening. 19, 5, p. 614-627 14 p.

Research output: Contribution to journalReview article

19 Scopus citations

Development of a mouse model of menopausal ovarian cancer

Smith, E. R., Wang, Y. & Xu, X. X., Jan 1 2014, In : Frontiers in Oncology. 4 MAR, Article 36.

Research output: Contribution to journalReview article

9 Scopus citations

From Mechanosensitivity to Inflammatory Responses: New Players in the Pathology of Glaucoma

Križaj, D., Ryskamp, D. A., Tian, N., Tezel, G., Mitchell, C. H., Slepak, V. Z. & Shestopalov, V. I., Feb 1 2014, In : Current Eye Research. 39, 2, p. 105-119 15 p.

Research output: Contribution to journalReview article

75 Scopus citations

Molecular pathways of pannexin1-mediated neurotoxicity

Shestopalov, V. I. & Slepak, V. Z., Jan 1 2014, In : Frontiers in Physiology. 5 FEB, Article 23.

Research output: Contribution to journalReview article

26 Scopus citations

Recent advances in the design and development of soft drugs

Buchwald, P. & Bodor, N., Jun 2014, In : Pharmazie. 69, 6, p. 403-413 11 p.

Research output: Contribution to journalReview article

14 Scopus citations
2013

G protein co-signaling and challenges for translational research

Litosch, I., Mar 1 2013, In : Translational Neuroscience. 4, 1, p. 66-73 8 p.

Research output: Contribution to journalReview article

3 Scopus citations

MicroRNAs: A new piece in the paediatric cardiovascular disease puzzle

Omran, A., Elimam, D., Webster, K. A., Shehadeh, L. A. & Yin, F., Oct 1 2013, In : Cardiology in the young. 23, 5, p. 642-655 14 p.

Research output: Contribution to journalReview article

18 Scopus citations

NMNATs, evolutionarily conserved neuronal maintenance factors

Ali, Y. O., Li-Kroeger, D., Bellen, H. J., Zhai, R. G. & Lu, H. C., Nov 1 2013, In : Trends in Neurosciences. 36, 11, p. 632-640 9 p.

Research output: Contribution to journalReview article

33 Scopus citations
2012
24 Scopus citations

Lessons from yeast for clathrin-mediated endocytosis

Boettner, D. R., Chi, R. J. & Lemmon, S. K., Jan 1 2012, In : Nature Cell Biology. 14, 1, p. 2-10 9 p.

Research output: Contribution to journalReview article

74 Scopus citations

MicroRNAs and neuronal development

Motti, D., Bixby, J. L. & Lemmon, V. P., Dec 1 2012, In : Seminars in Fetal and Neonatal Medicine. 17, 6, p. 347-352 6 p.

Research output: Contribution to journalReview article

21 Scopus citations

Mitochondrial membrane permeabilization and cell death during myocardial infarction: Roles of calcium and reactive oxygen species

Webster, K. A., Nov 1 2012, In : Future Cardiology. 8, 6, p. 863-884 22 p.

Research output: Contribution to journalReview article

149 Scopus citations
2011

Effects of Combination of Proliferative Agents and Erythropoietin on Left Ventricular Remodeling Post-Myocardial Infarction

Kanashiro-Takeuchi, R. M., Takeuchi, L. M., Hatzistergos, K., Quevedo, H., Selem, S. M., Treuer, A. V., Premer, C., Balkan, W., Margitich, I., Song, Y., Hu, Q. & Hare, J. M., Jun 1 2011, In : Clinical and Translational Science. 4, 3, p. 168-174 7 p.

Research output: Contribution to journalReview article

2 Scopus citations

nNOS regulation of skeletal muscle fatigue and exercise performance

Percival, J. M., Dec 1 2011, In : Biophysical Reviews. 3, 4, p. 209-217 9 p.

Research output: Contribution to journalReview article

15 Scopus citations
34 Scopus citations
2010

Cardiac troponin mutations and restrictive cardiomyopathy

Potter, J. D., Parvatiyar, M. S., Pinto, J. R. & Dweck, D., Jul 19 2010, In : Journal of Biomedicine and Biotechnology. 2010, 350706.

Research output: Contribution to journalReview article

34 Scopus citations

Dealing with misfolded proteins: Examining the neuroprotective role of molecular chaperones in neurodegeneration

Ali, Y. O., Kitay, B. M. & Zhai, R. G., Oct 1 2010, In : Molecules. 15, 10, p. 6859-6887 29 p.

Research output: Contribution to journalReview article

30 Scopus citations

Mutations in Troponin that cause HCM, DCM AND RCM: What can we learn about thin filament function?

Willott, R. H., Gomes, A. V., Chang, A. N., Parvatiyar, M. S., Pinto, J. R. & Potter, J. D., May 1 2010, In : Journal of Molecular and Cellular Cardiology. 48, 5, p. 882-892 11 p.

Research output: Contribution to journalReview article

135 Scopus citations

Recent advances in retrometabolic drug design (RMDD) and development

Bodor, N. & Buchwald, P., Jun 1 2010, In : Pharmazie. 65, 6, p. 395-403 9 p.

Research output: Contribution to journalReview article

10 Scopus citations
67 Scopus citations
2009

Chapter 2 Human Diseases Associated with GPR54 Mutations

Gurgel Teles, M., Gontijo Silveira, L. F., Bianco, S. & Claudia Latronico, A., Dec 1 2009, In : Progress in Molecular Biology and Translational Science. 88, C, p. 33-56 24 p.

Research output: Contribution to journalReview article

Chapter 6 Structure, Function, and Localization of Gβ5-RGS Complexes

Slepak, V. Z., Dec 1 2009, In : Progress in Molecular Biology and Translational Science. 86, C, p. 157-203 47 p.

Research output: Contribution to journalReview article

20 Scopus citations

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme

Zhai, R. G., Rizzi, M. & Garavaglia, S., Sep 1 2009, In : Cellular and Molecular Life Sciences. 66, 17, p. 2805-2818 14 p.

Research output: Contribution to journalReview article

47 Scopus citations

The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism

Bianco, S. D. C. & Kaiser, U. B., Oct 1 2009, In : Nature Reviews Endocrinology. 5, 10, p. 569-576 8 p.

Research output: Contribution to journalReview article

166 Scopus citations
2008

Mechanism of light-induced translocation of arrestin and transducin in photoreceptors: Interaction-restricted diffusion

Slepak, V. Z. & Hurley, J. B., Dec 1 2008, In : IUBMB life. 60, 1, p. 2-9 8 p.

Research output: Contribution to journalReview article

50 Scopus citations

Stress hyperglycemia and enhanced sensitivity to myocardial infarction

Webster, K. A., Feb 1 2008, In : Current Hypertension Reports. 10, 1, p. 78-84 7 p.

Research output: Contribution to journalReview article

17 Scopus citations

Thyroid-adrenergic interactions: Physiological and clinical implications

Silva, J. E. & Bianco, S. D. C., Feb 1 2008, In : Thyroid. 18, 2, p. 157-165 9 p.

Research output: Contribution to journalReview article

125 Scopus citations
2007

Computer-aided retrometabolic drug design: Soft drugs

Buchwald, P., Jul 1 2007, In : Expert Opinion on Drug Discovery. 2, 7, p. 923-933 11 p.

Research output: Contribution to journalReview article

5 Scopus citations

Golgi complex organization in skeletal Muscle: A role for Golgi-mediated Glycosylation in muscular dystrophies?

Percival, J. M. & Froehner, S. C., Mar 1 2007, In : Traffic. 8, 3, p. 184-194 11 p.

Research output: Contribution to journalReview article

21 Scopus citations

Hypoxia: Life on the edge

Webster, K. A., Sep 1 2007, In : Antioxidants and Redox Signaling. 9, 9, p. 1303-1307 5 p.

Research output: Contribution to journalReview article

20 Scopus citations

Mechanisms that regulate establishment, maintenance, and remodeling of dendritic fields

Parrish, J. Z., Emoto, K., Kim, M. D. & Yuh, N. J., Aug 13 2007, In : Annual Review of Neuroscience. 30, p. 399-423 25 p.

Research output: Contribution to journalReview article

187 Scopus citations

Myosin essential light chain in health and disease

Hernandez, O. M., Jones, M., Guzman, G. & Szczesna-Cordary, D., Apr 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 4, p. H1643-H1654

Research output: Contribution to journalReview article

87 Scopus citations

Programmed death as a therapeutic target to reduce myocardial infarction

Webster, K. A., Sep 1 2007, In : Trends in Pharmacological Sciences. 28, 9, p. 492-499 8 p.

Research output: Contribution to journalReview article

39 Scopus citations
2006

Antibodies and antibody-fusion proteins as anti-angiogenic, anti-tumor agents

Calfa, C. I., Rosenblatt, J. D., Cho, H. M., Webster, K. & Shin, S. U., Jun 1 2006, In : Update on Cancer Therapeutics. 1, 2, p. 159-173 15 p.

Research output: Contribution to journalReview article

6 Scopus citations

Brain-targeted delivery of estradiol: Therapeutic potential and results obtained with a chemical delivery system approach

Bodor, N. & Buchwald, P., Sep 12 2006, In : American Journal of Drug Delivery. 4, 3, p. 161-175 15 p.

Research output: Contribution to journalReview article

7 Scopus citations

Brain-targeted delivery of peptides

Bodor, N. & Buchwald, P., Jan 1 2006, In : American Pharmaceutical Review. 9, 1, p. 100-104 5 p.

Research output: Contribution to journalReview article

2 Scopus citations