Molecular and Cellular Pharmacology

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MicroRNAs and neuronal development

Motti, D., Bixby, J. & Lemmon, V., Dec 1 2012, In : Seminars in Fetal and Neonatal Medicine. 17, 6, p. 347-352 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury

Hellal, F., Hurtado, A., Ruschel, J., Flynn, K. C., Laskowski, C. J., Umlauf, M., Kapitein, L. C., Strikis, D., Lemmon, V., Bixby, J., Hoogenraad, C. C. & Bradke, F., Feb 18 2011, In : Science. 331, 6019, p. 928-931 4 p.

Research output: Contribution to journalArticle

328 Scopus citations

Minimum information about a spinal cord injury experiment: A proposed reporting standard for spinal cord injury experiments

Lemmon, V., Ferguson, A. R., Popovich, P. G., Xu, X. M., Snow, D. M., Igarashi, M., Beattie, C. E. & Bixby, J., Aug 1 2014, In : Journal of Neurotrauma. 31, 15, p. 1354-1361 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

MiR-211/STAT5A Signaling Modulates Migration of Mesenchymal Stem Cells to Improve its Therapeutic Efficacy

Hu, X., Chen, P., Wu, Y., Wang, K., Xu, Y., Chen, H., Zhang, L., Wu, R., Webster, K. A., Yu, H., Zhu, W. & Wang, J., Jul 1 2016, In : Stem Cells. 34, 7, p. 1846-1858 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
34 Scopus citations
7 Scopus citations

Mitochondrial membrane permeabilization and cell death during myocardial infarction: Roles of calcium and reactive oxygen species

Webster, K. A., Nov 1 2012, In : Future Cardiology. 8, 6, p. 863-884 22 p.

Research output: Contribution to journalArticle

149 Scopus citations

Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation

Dougherty, C. J., Kubasiak, L. A., Frazier, D. P., Li, H., Xiong, W. C., Bishopric, N. & Webster, K. A., Jul 1 2004, In : FASEB Journal. 18, 10, p. 1060-1070 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice

Siegel, M. P., Kruse, S. E., Percival, J., Goh, J., White, C. C., Hopkins, H. C., Kavanagh, T. J., Szeto, H. H., Rabinovitch, P. S. & Marcinek, D. J., Oct 1 2013, In : Aging Cell. 12, 5, p. 763-771 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

Mob2p interacts with the protein kinase Orb6p to promote coordination of cell polarity with cell cycle progression

Hou, M. C., Wiley, D. J., Verde, F. & McCollum, D., Jan 1 2003, In : Journal of Cell Science. 116, 1, p. 125-135 11 p.

Research output: Contribution to journalArticle

63 Scopus citations

Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x

Ing, D. J., Zang, J., Dzau, V. J., Webster, K. A. & Bishopric, N., Jan 8 1999, In : Circulation Research. 84, 1, p. 21-33 13 p.

Research output: Contribution to journalArticle

222 Scopus citations

Modulation of neuronal nicotinic acetylcholine receptors by mercury

Mirzoian, A. & Luetje, C. W., Jul 30 2002, In : Journal of Pharmacology and Experimental Therapeutics. 302, 2, p. 560-567 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
5 Scopus citations

Molecular aspects and gene therapy prospects for diastolic failure

Webster, K. A. & Bishopric, N., Sep 19 2000, In : Cardiology Clinics. 18, 3, p. 621-635 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Molecular mechanism of muscle contraction: New perspectives and ideas

Matusovsky, O. S., Mayans, O. & Szczesna-Cordary, D., 2015, In : BioMed Research International. 2015, 694345.

Research output: Contribution to journalArticle

2 Scopus citations

Molecular mechanisms of axon growth and guidance

Bixby, J. & Harris, W. A., Jan 1 1991, In : Annual Review of Cell Biology. 7, p. 117-159 43 p.

Research output: Contribution to journalArticle

257 Scopus citations
15 Scopus citations

Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gβ5-RGS7

Sandiford, S. L., Wang, Q., Levay, K., Buchwald, P. & Slepak, V. Z., Jun 22 2010, In : Biochemistry. 49, 24, p. 4998-5006 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Molecular pathways of pannexin1-mediated neurotoxicity

Shestopalov, V. I. & Slepak, V. Z., Jan 1 2014, In : Frontiers in Physiology. 5 FEB, Article 23.

Research output: Contribution to journalArticle

26 Scopus citations

Molecular receptive range variation among mouse odorant receptors for aliphatic carboxylic acids

Repicky, S. E. & Luetje, C. W., Apr 1 2009, In : Journal of Neurochemistry. 109, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP

Yamashita, K., Discher, D. J., Hu, J., Bishopric, N. & Webster, K. A., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 12645-12653 9 p.

Research output: Contribution to journalArticle

261 Scopus citations

Molecular switches for regulating therapeutic genes

Webster, K. A., Jul 6 1999, In : Gene Therapy. 6, 6, p. 951-953 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Motor neurite outgrowth is selectively inhibited by cell surface MuSK and agrin

Dimitropoulou, A. & Bixby, J., Feb 1 2005, In : Molecular and Cellular Neuroscience. 28, 2, p. 292-302 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

MsrA protects cardiac myocytes against hypoxia/reoxygenation induced cell death

Prentice, H. M., Moench, I. A., Rickaway, Z. T., Dougherty, C. J., Webster, K. A. & Weissbach, H., Feb 15 2008, In : Biochemical and Biophysical Research Communications. 366, 3, p. 775-778 4 p.

Research output: Contribution to journalArticle

45 Scopus citations
89 Scopus citations

Multiple determinants of dihydro-β-erythroidine sensitivity on rat neuronal nicotinic receptor α subunits

Harvey, S. C., Maddox, F. N. & Luetje, C. W., Nov 1 1996, In : Journal of Neurochemistry. 67, 5, p. 1953-1959 7 p.

Research output: Contribution to journalArticle

144 Scopus citations

Multiple mechanisms for regulation of steroid hormone action

Burnstein, K. L. & Cidlowski, J. A., Feb 26 1993, In : Journal of Cellular Biochemistry. 51, 2, p. 130-134 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Mutagenesis and analysis of genetic mutations in the GC-rich KISS1 receptor sequence identified in humans with reproductive disorders

da Silva, L. M., Vandepas, L. & Bianco, S. D. C., Sep 1 2011, In : Journal of Visualized Experiments. 55, e2897.

Research output: Contribution to journalArticle

3 Scopus citations

Mutagenesis and analysis of genetic mutations in the GC-rich KISS1 receptor sequence identified in humans with reproductive disorders.

Madeira da Silva, L., Vandepas, L. & Bianco, S. D. C., Dec 1 2011, In : Journal of visualized experiments : JoVE. 55

Research output: Contribution to journalArticle

Mutant cycle analysis identifies a ligand interaction site in an odorant receptor of the malaria vector Anopheles gambiae

Rahman, S. & Luetje, C. W., Jan 1 2017, In : Journal of Biological Chemistry. 292, 46, p. 18916-18923 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mutations in ATP1A1 Cause Dominant Charcot-Marie-Tooth Type 2

Lassuthova, P., Rebelo, A. P., Ravenscroft, G., Lamont, P. J., Davis, M. R., Manganelli, F., Feely, S. M., Bacon, C., Brožková, D. Š., Haberlova, J., Mazanec, R., Tao, F., Saghira, C., Abreu, L., Courel, S., Powell, E., Buglo, E., Bis, D. M., Baxter, M. F., Ong, R. W. & 14 others, Marns, L., Lee, Y. C., Bai, Y., Isom, D. G., Barro-Soria, R., Chung, K. W., Scherer, S. S., Larsson, H. P., Laing, N. G., Choi, B. O., Seeman, P., Shy, M. E., Santoro, L. & Zuchner, S., Mar 1 2018, In : American Journal of Human Genetics. 102, 3, p. 505-514 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Mutations of the KISS1 gene in disorders of puberty

Silveira, L. G., Noel, S. D., Silveira-Neto, A. P., Abreu, A. P., Brito, V. N., Santos, M. G., Bianco, S. D. C., Kuohung, W., Xu, S., Gryngarten, M., Escobar, M. E., Arnhold, I. J. P., Mendonca, B. B., Kaiser, U. B. & Latronico, A. C., May 1 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2276-2280 5 p.

Research output: Contribution to journalArticle

179 Scopus citations

Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way

Zhu, J., Lu, K., Zhang, N., Zhao, Y., Ma, Q., Shen, J., Lin, Y., Xiang, P., Tang, Y., Hu, X., Chen, J., Zhu, W., Webster, K. A., Wang, J. & Yu, H., Nov 14 2017, (Accepted/In press) In : Artificial Cells, Nanomedicine and Biotechnology. p. 1-12 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Myocyte deficiency as a target in the treatment of cardiomyopathy

Rodrigues, C. D., Shehadeh, L., Webster, K. A. & Bishopric, N., Sep 1 2007, In : Progress in Pediatric Cardiology. 23, 1-2, p. 49-59 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Myosin essential light chain in health and disease

Hernandez, O. M., Jones, M., Guzman, G. & Szczesna-Cordary, D., Apr 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 4

Research output: Contribution to journalArticle

87 Scopus citations

Myosin regulatory light chain E22K mutation results in decreased cardiac intracellular calcium and force transients

Szczesna-Cordary, D., Jones, M., Moore, J. R., Watt, J., Kerrick, W. G., Xu, Y., Wang, Y., Wagg, C. & Lopaschuk, G. D., Dec 1 2007, In : FASEB Journal. 21, 14, p. 3974-3985 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Myosin regulatory light chain mutation found in hypertrophic cardiomyopathy patients increases isometric force production in transgenic mice

Kazmierczak, K., Muthu, P., Huang, W., Jones, M., Wang, Y. & Szczesna-Cordary, D., Feb 15 2012, In : Biochemical Journal. 442, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Myosin regulatory light chain phosphorylation enhances cardiac β-myosin in vitro motility under load

Karabina, A., Kazmierczak, K., Szczesna-Cordary, D. & Moore, J. R., Jul 6 2015, In : Archives of Biochemistry and Biophysics. 580, p. 14-21 8 p., 7007.

Research output: Contribution to journalArticle

16 Scopus citations

Na+ promotes the dissociation between GαGDP and Gβγ, activating G protein-gated K+ channels

Rishal, I., Keren-Raifman, T., Yakubovich, D., Ivanina, T., Dessauer, C. W., Slepak, V. Z. & Dascal, N., Feb 7 2003, In : Journal of Biological Chemistry. 278, 6, p. 3840-3845 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration

Zhai, R. G., Zhang, F., Hiesinger, P. R., Cao, Y., Haueter, C. M. & Bellen, H. J., Apr 17 2008, In : Nature. 452, 7189, p. 887-891 5 p.

Research output: Contribution to journalArticle

138 Scopus citations

Neonatal asphyxia induces the nitration of cardiac myosin light chain 2 that is associated with cardiac systolic dysfunction

Doroszko, A., Polewicz, D., Cadete, V. J. J., Sawicka, J., Jones, M., Szczesna-Cordary, D., Cheung, P. Y. & Sawicki, G., Dec 1 2010, In : Shock. 34, 6, p. 592-600 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism

Jo, S., Kalló, I., Bardóczi, Z., e Drigo, R. A., Zeöld, A., Liposits, Z., Oliva, A., Lemmon, V., Bixby, J., Gereben, B. & Bianco, A. C., Jun 20 2012, In : Journal of Neuroscience. 32, 25, p. 8491-8500 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity

Parker, M. J., Beck, A. & Luetje, C. W., Dec 1 1998, In : Molecular Pharmacology. 54, 6, p. 1132-1139 8 p.

Research output: Contribution to journalArticle

152 Scopus citations

Neuronal pentraxin with chromo domain (NPCD) is a novel class of protein expressed in multiple neuronal domains

Chen, B. & Bixby, J., Jan 24 2005, In : Journal of Comparative Neurology. 481, 4, p. 391-402 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor

Takeuchi, R., Szalontay, L., Schally, A. V., Takeuchi, L. M., Popovics, P., Jaszberenyi, M., Vidaurre, I., Zarandi, M., Cai, R. Z., Block, N. L., Hare, J. & Rick, F. G., 2015, In : Oncotarget. 6, 12, p. 9728-9739 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme

Zhai, R. G., Rizzi, M. & Garavaglia, S., Sep 1 2009, In : Cellular and Molecular Life Sciences. 66, 17, p. 2805-2818 14 p.

Research output: Contribution to journalArticle

47 Scopus citations

Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1α pathway

Ali, Y. O., McCormack, R., Darrand, A. & Zhai, R. G., May 27 2011, In : Journal of Biological Chemistry. 286, 21, p. 19089-19099 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Nicotinamide mononucleotide adenylyltransferase maintains active zone structure by stabilizing Bruchpilot

Zang, S., Ali, Y. O., Ruan, K. & Zhai, R. G., Jan 1 2013, In : EMBO Reports. 14, 1, p. 87-94 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling

Zhou, M. S., Chadipiralla, K., Mendez, A. J., Jaimes, E. A., Silverstein, R. L., Webster, K. A. & Raij, L., May 8 2013, In : American Journal of Physiology - Heart and Circulatory Physiology. 305, 4

Research output: Contribution to journalArticle

29 Scopus citations

Nitric Oxide Regulates Skeletal Muscle Fatigue, Fiber Type, Microtubule Organization, and Mitochondrial ATP Synthesis Efficiency Through cGMP-Dependent Mechanisms

Moon, Y., Balke, J. E., Madorma, D., Siegel, M. P., Knowels, G., Brouckaert, P., Buys, E. S., Marcinek, D. J. & Percival, J., Jun 10 2017, In : Antioxidants and Redox Signaling. 26, 17, p. 966-985 20 p.

Research output: Contribution to journalArticle

11 Scopus citations